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1. 发明申请

WO2016179094A1 RAPID MAPPING OF LANGUAGE FUNCTION AND MOTOR FUNCTION WITHOUT SUBJECT PARTICIPATION 审中-公开
标题翻译：无参与语言功能和电机功能的快速映射
公开(公告)号：WO2016179094A1
公开(公告)日：2016-11-10
申请号：PCT/US2016/030418
申请日：2016-05-02
申请人： HEALTH RESEARCH, INC. , ALBANY MEDICAL COLLEGE
发明人： SCHALK, Gerwin , RITACCIO, Anthony L. , DE PESTERS, Adriana , TAPLIN, AmiLyn
IPC分类号： A61B5/04 , A61B5/00 , A61F2/00 , A61F2/72 , A61N1/18 , G06F19/00
CPC分类号： A61N1/36082 , A61B5/04845 , A61B5/4064 , A61B5/4094 , A61B2505/05 , A61N1/0531 , A61N1/32 , G06F19/3481
摘要： Provided is a method for mapping a neural area involved in speech processing, including applying a plurality of recording electrodes to a surface of a cortex of a human subject, presenting a plurality of auditory stimuli to the subject wherein some of the plurality of stimuli are speech sounds and others of the plurality of auditory stimuli are non-speech sounds, recording brain activity during the presenting of the plurality of auditory stimuli, and identifying one or more brain areas wherein activity changes more after presentation of speech sounds than it does after presentation of non-speech sounds, wherein the human subject does not speak during the presenting and the recording. Also provided is a method for mapping a neural area involved in speech production wherein the human subject does not speak during presenting speech stimuli and recording neural activity.
摘要翻译：提供了一种用于映射涉及语音处理的神经区域的方法，包括将多个记录电极施加到人类对象的皮质表面，向对象呈现多个听觉刺激，其中多个刺激中的一些是语音多个听觉刺激中的声音和其他声音是非语音的，在呈现多个听觉刺激期间记录脑活动，以及识别一个或多个脑区域，其中在呈现语音之后活动在演讲之后更多地比在呈现非语音，其中人物在呈现和记录期间不说话。还提供了一种用于映射涉及语音制作的神经区域的方法，其中人类对象在呈现言语刺激和记录神经活动期间不会说话。

2. 发明申请

WO2016149538A1 IMPROVED MEASUREMENT OF CORTICAL EXCITABILITY 审中-公开
标题翻译：改进了光栅性能的测量
公开(公告)号：WO2016149538A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022946
申请日：2016-03-17
申请人： HEALTH RESEARCH, INC.
发明人： SCHALK, Gerwin , BRUNNER, Peter , COON, William G. , DE PESTERS, Adriana
IPC分类号： A61N1/36
CPC分类号： A61B5/0484 , A61B5/04001 , A61B5/04017 , A61B5/0478 , A61B5/4836 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36139
摘要： The present invention includes a responsive neural stimulator having electrodes, a filter, a processor, a recording medium, an extractor for extracting instantaneous voltage amplitudes of biased oscillatory activity with asymmetrically distributed peak/trough amplitudes, and a neural stimulator connected to the processor configured to apply neural stimulation via the neural stimulator when a predetermined state of neuronal excitability is detected, a state of relatively higher neuronal excitability corresponding to a relatively lower instantaneous voltage amplitude extracted by the extractor. Also provided is a system for providing neurofeedback including electrodes, a filter, a processor, a recording medium, an extractor for extracting instantaneous voltage amplitudes of biased oscillatory activity with asymmetrically distributed peak/trough amplitudes, and an output device configured to communicate changes in, increases in, decreases in, or maintenance of instantaneous voltage amplitudes, or any combination, to a participant in a neurofeedback session.
摘要翻译：本发明包括具有电极，滤波器，处理器，记录介质，用于以非对称分布的峰/谷幅度提取偏置振荡活动的瞬时电压振幅的提取器的响应性神经刺激器，以及连接到处理器的神经刺激器，当检测到神经元兴奋性的预定状态时，通过神经刺激器施加神经刺激，对应于由提取器提取的相对较低的瞬时电压振幅的相对较高的神经元兴奋性的状态。还提供了一种用于提供神经反馈的系统，包括电极，滤波器，处理器，记录介质，用于提取具有不对称分布的峰/谷幅度的偏置振荡活动的瞬时电压幅度的提取器，以及输出设备，向神经反馈会话中的参与者增加，减少或维持瞬时电压幅度或任何组合。

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