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1. 发明申请

WO2012135459A1 APPARATUS AND METHOD FOR VENTING GAS FROM A LIQUID 审中-公开
标题翻译：用于从液体中喷出气体的装置和方法
公开(公告)号：WO2012135459A1
公开(公告)日：2012-10-04
申请号：PCT/US2012/031153
申请日：2012-03-29
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC. , CRNKOVICH, Martin, Joseph , WEAVER, Colin
发明人： CRNKOVICH, Martin, Joseph , WEAVER, Colin
IPC分类号： B01D19/00 , B01D36/00 , B01D36/04
CPC分类号： A61M1/16 , A61M1/14 , A61M1/3624 , A61M1/3627 , A61M2205/123 , A61M2205/3382 , A61M2205/3386 , B01D19/0063 , Y10T137/0318 , Y10T137/309
摘要： The present invention relates to an apparatus and method for venting a gas from a liquid, which are applicable to a wide variety of medical liquid delivery systems. The apparatus includes level detectors, a clamp, and a control apparatus operably connected to the level detectors and the clamp. The method includes detecting whether liquid or gas is present at the level detectors, and opening and closing a clamp to vent gas.
摘要翻译：本发明涉及一种用于从液体排出气体的装置和方法，其适用于各种各样的医用液体输送系统。该装置包括液位检测器，夹具和可操作地连接到液位检测器和夹具的控制装置。该方法包括检测液位检测器中是否存在液体或气体，以及打开和关闭夹具以排出气体。

2. 发明申请

WO2012166377A1 METHOD AND SYSTEM FOR INLET TEMPERATURE MONITORING FOR CENTRALIZED HEAT DISINFECTION OF DIALYSIS MACHINE INLET LINES 审中-公开
标题翻译：吸水机进线集中热消毒入口温度监测方法及系统
公开(公告)号：WO2012166377A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/038329
申请日：2012-05-17
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC. , KOTSOS, Michael, Emmanuel , WANG, Fei , CRNKOVICH, Martin, Joseph
发明人： KOTSOS, Michael, Emmanuel , WANG, Fei , CRNKOVICH, Martin, Joseph
IPC分类号： A61M1/16
CPC分类号： A61M1/1686 , A61M2205/3368 , A61M2205/3561 , A61M2205/3584 , A61M2205/3592
摘要： A method for inlet temperature monitoring for centralized heat disinfection of dialysis machine inlet lines is described. The method can be used, for example, for a dialysis system which has a central water processing system used at a multiple patient dialysis treatment clinic or center. A central water processing system and a plurality of dialysis machines having fluid inlets are fluidly connected to a water supply loop which circulates heated water from the central water processing system to the dialysis machines and back to the central water processing system. Water temperatures are sensed with temperature sensors at the fluid inlets of the dialysis machines on the loop, and data on the sensed temperatures is communicated to a process controller capable of comparing the sensed temperatures to a predetermined value or value range selected for disinfection, and resolving any discrepancies by issuing an alarm and/or controlling a temperature controller to adjust water temperature of water at the central water processing system. A dialysis system for centralized heat disinfection of dialysis machine inlet lines of dialysis machines supplied with water by a central water processing system also is provided.
摘要翻译：介绍了透析机入口管线集中热消毒入口温度监测方法。该方法可以用于例如具有在多个患者透析治疗诊所或中心使用的中央水处理系统的透析系统。具有流体入口的中央水处理系统和多个透析机流体地连接到将加热的水从中央水处理系统循环到透析机并返回到中央水处理系统的供水回路。在循环中的透析机的流体入口处用温度传感器感测水温，并且将感测到的温度的数据传送到能够将感测到的温度与选择用于消毒和解决的预定值或值范围进行比较的过程控制器通过发出报警和/或控制温度控制器来调节中央水处理系统的水温的任何差异。还提供了一种用于通过中央水处理系统提供水的透析机的透析机入口管线的集中热消毒的透析系统。

3. 发明申请

WO2009039225A1 AUTOMATIC PRIME OF AN EXTRACORPOREAL BLOOD CIRCUIT 审中-公开
标题翻译：超声波血液循环的自动化
公开(公告)号：WO2009039225A1
公开(公告)日：2009-03-26
申请号：PCT/US2008/076751
申请日：2008-09-18
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC. , FOLDEN, Thomas, Irvin , CRNKOVICH, Martin, Joseph
发明人： FOLDEN, Thomas, Irvin , CRNKOVICH, Martin, Joseph
IPC分类号： A61M1/36
CPC分类号： A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649
摘要： A system for priming an extracorporeal blood circuit is described. The system includes a fluid circuit (200) with an air venting mechanism, a reversible pump (222), arterial and venous lines, a prime waste bag (285) and a switchable coupler (220) selectively connecting the arterial and venous lines to the waste bag or alternatively interconnecting the arterial and venous lines. A priming fluid is connected to the circuit and circulated in the circuit under different configurations of the arterial and venous line connections.
摘要翻译：描述了用于引发体外血液回路的系统。该系统包括具有排气机构的流体回路（200），可逆泵（222），动脉和静脉线，主要废物袋（285）和可切换耦合器（220），其选择性地将动脉和静脉线连接到废物袋或交替地连接动脉和静脉线。启动流体连接到电路，并在电路中在动脉和静脉线连接的不同配置下循环。

4. 发明申请

WO2013074635A2 REMOTE CONTROL OF DIALYSIS MACHINES 审中-公开
标题翻译：透析机的远程控制
公开(公告)号：WO2013074635A2
公开(公告)日：2013-05-23
申请号：PCT/US2012/065021
申请日：2012-11-14
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC. , WANG, Aiyuan , CRNKOVICH, Martin, Joseph , WANG, Fei , LEE, Sue-Jane , YUDS, David , LEUNG, Hak Kan , TAM, Jeffrey
发明人： WANG, Aiyuan , CRNKOVICH, Martin, Joseph , WANG, Fei , LEE, Sue-Jane , YUDS, David , LEUNG, Hak Kan , TAM, Jeffrey
IPC分类号： G06F15/16 , G06F21/00
CPC分类号： H04L67/125 , A61M1/1601 , A61M2205/18 , A61M2205/3553 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , G06F19/00 , G06F19/3418 , G06F19/3456 , G06F19/3481 , G16H20/10 , G16H40/67 , H04L63/10 , H04L67/141
摘要： This disclosure relates to remote control of dialysis machines (102). In certain aspects, a method includes receiving a request for a network connection from a dialysis machine (402) and establishing the network connection with the dialysis machine (404, 406, 408). The method also includes receiving, from a client device, a request to access the dialysis machine (412), authorizing the client device to access the dialysis machine (414, 416), receiving, from the dialysis machine, information pertaining to an operation of the dialysis machine (422), and providing, to the client device, the received information (424).
摘要翻译：本公开涉及透析机（102）的远程控制。在某些方面，一种方法包括从透析机（402）接收对网络连接的请求并建立与透析机（404,406,408）的网络连接。该方法还包括从客户端设备接收访问透析机（412）的请求，授权客户端设备访问透析机（414,416），从透析机接收与操作相关的信息透析机（422），并向客户端设备提供所接收的信息（424）。

5. 发明申请

WO2007050211A2 EXTRACORPOREAL FLUID CIRCUIT 审中-公开
标题翻译：超声波流体电路
公开(公告)号：WO2007050211A2
公开(公告)日：2007-05-03
申请号：PCT/US2006/036802
申请日：2006-09-20
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC. , FOLDEN, Thomas, Irvin , CRNKOVICH, Martin, Joseph , SCHLAEPER, Christian , JENSEN, Lynn , REIHANIFAM, Mohsen
发明人： FOLDEN, Thomas, Irvin , CRNKOVICH, Martin, Joseph , SCHLAEPER, Christian , JENSEN, Lynn , REIHANIFAM, Mohsen
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M1/3643 , A61M2205/123 , A61M2205/7536 , A61M2205/7563
摘要： A chamber is described for use in an extracorporeal fluid system. The chamber has a bottom entry port and a bottom exit port. A microporous filter at the top of the chamber allows air in the fluid to vent from the chamber. In use, the chamber is filled with saline. Blood is then introduced into the chamber. A layer of saline is above a layer of blood in the chamber. The saline stagnates as the blood flows through the chamber. The saline keeps the blood from contacting the filter and depositing protein on the filter.
摘要翻译：描述了一个用于体外流体系统的腔室。该室具有底部入口和底部出口。在室的顶部的微孔过滤器允许流体中的空气从腔室排出。在使用中，室内充满盐水。然后将血液引入腔室。一层盐水在腔室中的一层血液之上。当血液流过腔室时，盐水停滞。盐水保持血液不接触过滤器并将蛋白质沉积在过滤器上。

6. 发明申请

WO2021067247A1 DRAIN APPARATUS FOR HEMODIALYSIS MACHINES 审中-公开
公开(公告)号：WO2021067247A1
公开(公告)日：2021-04-08
申请号：PCT/US2020/053235
申请日：2020-09-29
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC.
发明人： CRNKOVICH, Martin, Joseph , WEAVER, Colin , YUDS, David
IPC分类号： A61M1/16 , A61M1/36
摘要： This disclosure relates to dialysis systems and methods. In some implementations, a dialysis system includes a dialysis machine with a fluid line and a drain line, a blood line set configured to be connected to the dialysis machine, and a drain apparatus coupled to the dialysis machine. The drain apparatus includes a chamber configured to receive an end of a patient line of the blood line set, an inlet line, an outlet line, and a valve. The inlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the fluid line of the dialysis machine. The outlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the drain line of the dialysis machine. The valve is configured to control flow of fluid through the outlet line.

7. 发明申请

WO2021021389A1 INTEGRATED CROSS CONTAMINATION SENSORS 审中-公开
公开(公告)号：WO2021021389A1
公开(公告)日：2021-02-04
申请号：PCT/US2020/040855
申请日：2020-07-06
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC. , FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
发明人： CRNKOVICH, Martin, Joseph , WEAVER, Colin , SCHLAEPER, Christian
IPC分类号： A61M1/16 , A61M1/28
摘要： In some embodiments, a medical system includes a dialysis machine having at least one outer surface to be disinfected at a given location, at least one disinfection sensor connected to the dialysis machine at the given location, the disinfection sensor including two or more electrode in fluid contact with the outside surface of the dialysis machine, and a conductivity sensor component in electrical contact with the two or more electrodes, the conductivity sensor component configured to send an electrical signal indicating a conductivity of a liquid on an outside surface of the dialysis machine and in contact with the two or more electrodes, a processor configured to receive the electrical signal and thereby determine a disinfection status of the given location, and a user interface configured to indicate the disinfection status of the given location.

8. 发明申请

WO2019099157A1 REMOVAL OF MICROBUBBLES THROUGH DRIP CHAMBER NUCLEATION SITES 审中-公开
公开(公告)号：WO2019099157A1
公开(公告)日：2019-05-23
申请号：PCT/US2018/057196
申请日：2018-10-24
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC.
发明人： YUDS, David , CRNKOVICH, Martin, Joseph , WEAVER, Colin
IPC分类号： A61M1/36 , B01D19/00 , A61M5/14
摘要： A drip chamber is provided that includes a hollow body and a nucleation column extending into the interior of the hollow body. The nucleation column can be formed with, or treated by a treatment to include, microfeatures or other surface properties that provide nucleation sites for the nucleation and amalgamation of microbubbles. The drip chamber can include a bubble catcher in the bottom of the hollow body and the nucleation column can extend from the bubble catcher into the interior of the hollow body. Methods of making such drip chambers are also provided.

9. 发明申请

WO2013138233A1 APPARATUS AND METHOD FOR VENTING GAS FROM A LIQUID 审中-公开
标题翻译：用于从液体中喷出气体的装置和方法
公开(公告)号：WO2013138233A1
公开(公告)日：2013-09-19
申请号：PCT/US2013/030182
申请日：2013-03-11
申请人： FRESENIUS MEDICAL CARE HOLDINGS, INC.
发明人： CRNKOVICH, Martin, Joseph , WEAVER, Colin
IPC分类号： A61M1/16
CPC分类号： A61M1/16 , A61M1/3624 , A61M1/3627 , A61M1/3639 , A61M1/3641 , A61M2205/123 , A61M2205/3331 , A61M2205/3382 , A61M2205/3386 , F04C2270/041 , Y10T137/3087
摘要： The present invention relates to an apparatus and method for venting a gas from a liquid, which are applicable to a wide variety of medical liquid delivery systems. The apparatus includes level detectors, a clamp, and a control apparatus operably connected to the level detectors and the clamp. The method includes detecting whether liquid or gas is present at the level detectors, and opening and closing a clamp to vent gas. The present invention also relates to an apparatus and method for controlling pressure differential across a semipermeable membrane by using a pressure sensor, a gas source, a valve, and a membrane.
摘要翻译：本发明涉及一种用于从液体排出气体的装置和方法，其适用于各种各样的医用液体输送系统。该装置包括液位检测器，夹具和可操作地连接到液位检测器和夹具的控制装置。该方法包括检测液位检测器中是否存在液体或气体，以及打开和关闭夹具以排出气体。本发明还涉及一种通过使用压力传感器，气体源，阀和膜来控制半透膜上的压差的装置和方法。

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