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1. 发明申请

WO2003070275A1 USE OF AN INHIBITOR OR ANTAGONIST AGAINST TISSUE FACTOR 审中-公开
标题翻译：使用抗组织蛋白酶抑制剂或拮抗剂
公开(公告)号：WO2003070275A1
公开(公告)日：2003-08-28
申请号：PCT/SE2003/000289
申请日：2003-02-21
申请人： FORSKARPATENT I UPPSALA AB , KORSGREN, Olle , NILSSON, Bo
发明人： KORSGREN, Olle , NILSSON, Bo
IPC分类号： A61K39/395
CPC分类号： C07K16/36 , A61K38/1709 , A61K2039/505
摘要： The present invention relates to use of an inhibitor or antagonist against tissue factor, TF, in the production of a drug for treatment or prevention of diabetes or diabetes related diseases. The inhibitor or antagonist is mainly intended for treatment of diabetic patients suffering from type I or type II diabetes, respectively, as well as the metabolic syndrome preceding type II diabetes. The inhibitor or antagonist is an agent which completely or partially inhibits TF productions, such as an anti-TF antibody or an antisense construct acting on the TF gene.
摘要翻译：本发明涉及抗组织因子TF的抑制剂或拮抗剂在制备用于治疗或预防糖尿病或糖尿病相关疾病的药物中的用途。抑制剂或拮抗剂主要用于治疗分别患有I型或II型糖尿病的糖尿病患者以及II型糖尿病前的代谢综合征。抑制剂或拮抗剂是完全或部分抑制TF产生的试剂，例如抗TF抗体或作用于TF基因的反义构建体。

2. 发明申请

WO2005030283A1 BIOARTIFICIAL IMPLANT AND ITS USE AND METHOD OF REDUCING THE RISK FOR FORMATION OF CONNECTIVE TISSUE AFTER IMPLANTATION 审中-公开
标题翻译：生物植入物及其使用和减少在植入后形成连接组织的风险的方法
公开(公告)号：WO2005030283A1
公开(公告)日：2005-04-07
申请号：PCT/SE2004/001418
申请日：2004-10-04
申请人： TIKOMED AB , BRUCE, Adam , BRUCE, Lars , NILSSON, Bo , KORSGREN, Olle
发明人： BRUCE, Adam , BRUCE, Lars , NILSSON, Bo , KORSGREN, Olle
IPC分类号： A61L27/50
CPC分类号： A61L27/306 , A61L27/50
摘要： A bioartificial implant comprises a semipermeable barrier designed from one side to allow diffusion or prevent diffusion of predetermined substances/materials/molecules/cells/cell lines produced in the human body to the other opposite side of the barrier, and from said other opposite side to allow diffusion or prevent diffusion of predetermined substances which are the same as or different from the first mentioned substances/materials/molecules/cells/cell lines. The semipermeable barrier has a surface coating at least on said one side a bioactive metal, such as titanium, which surface coating is permeable to allow said diffusions. In a method for reducing the risk of formation/growth of connective tissue in connection with an implant which comprises a semipermeable barrier, the barrier is provided at least on one side with a permeable coating of bioactive metal. An example of the use of the implant is bioartificial pancreas.
摘要翻译：生物人造植入物包括从一侧设计的半透膜，以允许扩散或防止在人体中产生的预定物质/材料/分子/细胞/细胞系扩散到屏障的另一相对侧，并且从所述另一相对侧扩散允许扩散或防止与前述物质/材料/分子/细胞/细胞系相同或不同的预定物质的扩散。所述半渗透屏障至少在所述一侧上具有生物活性金属（例如钛）的表面涂层，所述表面涂层是可渗透的，以允许所述扩散。在减少与包括半透性屏障的植入物相关的结缔组织形成/生长的风险的方法中，至少在一侧上设置有可渗透的生物活性金属涂层的屏障。使用植入物的实例是生物人造胰腺。

3. 发明申请

WO2012008908A1 CELL THERAPY 审中-公开
标题翻译：细胞治疗
公开(公告)号：WO2012008908A1
公开(公告)日：2012-01-19
申请号：PCT/SE2011/050928
申请日：2011-07-08
申请人： TX MEDIC AB , KORSGREN, Olle , NILSSON, Bo
发明人： KORSGREN, Olle , NILSSON, Bo
IPC分类号： A61K31/737 , A61K35/12 , A61P35/04
CPC分类号： A61K31/737 , A61K35/26
摘要： Dextran sulfate is used in order to reduce pulmonary uptake of intravenously injected Dextran sulfate is capable of reducing the pulmonary uptake of the intravenously injected cells to the levels obtained for intraarterial injection of the cells but without the accompanying risks and side effects of using intraarterial cell injection. The dextran sulfate can therefore be used in a composition together with tumor infiltrating T-lymphocytes to treat metastatic cancer in a subject.
摘要翻译：使用硫酸葡聚糖以减少静脉内注射的硫酸葡聚糖的肺吸收能够将静脉内注射的细胞的肺吸收降低至动脉内注射细胞获得的水平，但不伴随使用动脉内细胞注射的风险和副作用。因此，硫酸葡聚糖因此可以与肿瘤浸润性T淋巴细胞一起用于组合物中以治疗受试者的转移性癌症。

4. 发明申请

WO2004047848A1 NEW USE OF DEXTRAN SULFATE 审中-公开
标题翻译：新西兰硫酸锌的使用
公开(公告)号：WO2004047848A1
公开(公告)日：2004-06-10
申请号：PCT/SE2003/001830
申请日：2003-11-26
申请人： PROPHYMED AB , NILSSON, Bo , KORSGREN, Olle
发明人： NILSSON, Bo , KORSGREN, Olle
IPC分类号： A61K31/721
CPC分类号： A61K31/737 , A61K31/721 , A61K35/39 , A61L27/3804 , A61L27/3839 , A61L27/54 , A61L2300/232 , A61L2300/41 , A61L2300/45 , A61L2300/64
摘要： The present invention refers to use of dextran sulfate, or a pharmaceutically acceptable derivate thereof, for manufacturing of a medicament for treatment of Instant Blood-Mediated Inflammatory Reaction (IBMIR). In addition, the invention refers to the use of dextran sulfate, or a pharmaceutically acceptable derivate thereof, for manufacturing of a medicament for treatment of morphological disruption of cell transplants and graft-rejection of cell transplants caused by IBMIR. The invention may be applied to patients suffering from type I diabetes, in which porcine islets of Langerhans are transplanted in their portal vein. Administration of dextran sulfate according to the invention inhibits and prevents rejection and destruction of the transplanted islets and makes normoglycemia in the patients possible.
摘要翻译：本发明涉及硫酸葡聚糖或其药学上可接受的衍生物在制备用于治疗即时血液介导的炎性反应（IBMIR）的药物中的用途。此外，本发明涉及硫酸葡聚糖或其药学上可接受的衍生物在制备用于治疗由IBMIR引起的细胞移植的形态学破坏和细胞移植的移植排斥的药物中的用途。本发明可以应用于患有I型糖尿病的患者，其中在其门静脉中移植了朗格汉斯猪胰岛。根据本发明的硫酸葡聚糖的施用抑制并防止移植胰岛的排斥和破坏，并使患者的血糖异常成为可能。

5. 发明申请

WO2003061682A1 THE USE OF MELAGATRAN FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS 审中-公开
标题翻译： MELAGATRAN用于制造治疗1型糖尿病的药物的用途
公开(公告)号：WO2003061682A1
公开(公告)日：2003-07-31
申请号：PCT/SE2003/000087
申请日：2003-01-21
申请人： ASTRAZENECA AB , KORSGREN, Olle , NILSSON, Bo
发明人： KORSGREN, Olle , NILSSON, Bo
IPC分类号： A61K38/05
CPC分类号： A61K35/39 , A61K31/397 , A61K2300/00
摘要： According to the invention there is provided the use of melagatran, or a pharmaceutically-acceptable derivative thereof, for the manufacture of a medicament for the treatment of Type I diabetes
摘要翻译：根据本发明，提供了用于制备用于治疗I型糖尿病的药物的利拉曲坦或其药学上可接受的衍生物的用途

6. 发明申请

WO2010085198A1 CONVEX WOODCHIP BOARD 审中-公开
标题翻译： CONVEX木工板
公开(公告)号：WO2010085198A1
公开(公告)日：2010-07-29
申请号：PCT/SE2010/050034
申请日：2010-01-14
申请人： SWEDWOOD INTERNATIONAL AB , NILSSON, Bo
发明人： NILSSON, Bo
IPC分类号： B32B21/02 , B27N3/02 , B27N3/14 , B27N5/00
CPC分类号： B27N3/14 , B27N3/02 , B32B7/02 , B32B21/02 , B32B21/13 , B32B2307/54 , B32B2307/718 , B32B2479/00 , E04C2/16 , E04C2/328
摘要： The invention relates to a method for manufacturing a woodchip board (3) comprising a first (21) and second (23) woodchip layer sandwiching an intermediate layer (12) comprising woodchips of other chip size than the first (21) and second (23) woodchip layer. The method comprises the steps involving application of a first quantity (5) of glued woodchips (7) to a lower tool face (9) of a pressing tool (1, 31); application of a filler quantity (11) of glued woodchips (7') to the first quantity (5); application of a second quantity (13) of glued woodchips (7) to the filler quantity (11); compression of said quantities (5, 11, 13) by means of the lower (9) tool face and an upper tool face (15); realization of differentiated times when the glue of the glued woodchips (7) hardens in the first (5) and second quantity (13) respectively, by virtue of the production of these quantities with different thickness and/or by heating of the respective quantities (5, 13) to different temperatures; and removal of the hardened woodchip board (3) from the pressing tool (1, 31).
摘要翻译：本发明涉及一种用于制造木片板（3）的方法，所述木片板（3）包括夹着中间层（12）的第一（21）和第二（23）木芯层，所述中间层包括除了第一（21）和第二（23））木片层。该方法包括以下步骤：将第一数量（5）胶合的木片（7）施加到压制工具（1）的下工具面（9）上; 将粘合的木片（7'）的填料量（11）施加到第一数量（5）; 将第二数量（13）的胶合木片（7）施加到填料量（11）; 通过下（9）工具面和上工具面（15）压缩所述量（5,11,13）; 当粘合的木片（7）的胶水分别在第一（5）和第二数量（13）中硬化时，通过产生具有不同厚度的这些量和/或通过加热各自的量来实现差异化时间（ 5,13）到不同的温度; 以及从加压工具（1,31）中取出硬化的木片板（3）。

7. 发明申请

WO2003094769A1 DEVICE COMPRISING A PIN SUPPORT MEMBER AND INSULATION MEANS FOR FIXATION TO A PATIENS SKULL DURING NEUROLOGICAL DIAGNOSIS, AND A METHOD FOR ASSEMBLING SAID DEVICE. 审中-公开
标题翻译：包含PIN支持成员的装置和用于在神经病学诊断期间固定到患者的绝缘手段，以及用于组装上述装置的方法。
公开(公告)号：WO2003094769A1
公开(公告)日：2003-11-20
申请号：PCT/SE2003/000723
申请日：2003-05-06
申请人： ELEKTA AB , ARNDT, Jürgen , NILSSON, Bo , OLSSON, Jan-Erik
发明人： ARNDT, Jürgen , NILSSON, Bo , OLSSON, Jan-Erik
IPC分类号： A61B19/00
CPC分类号： A61B90/14
摘要： The present invention relates to a device for fixation to a patient during neurological diagnosis, therapy or surgery, in particular during MRI diagnosis. The device comprises at least one fixation pin being made of a non-magnetic, electrically conductive material for fixation to a patient, and at least one pin support member for supporting said fixation pin. An insulation means is arranged so as to restrict the electrical coupling between said pin support member and fixation pin. Said insulation means is sleeve shaped and arranged to at least partly surround said fixation pin. The invention also relates to an insulation means, a pin support member and to a method for assembling a fixation device.
摘要翻译：本发明涉及一种用于在神经系统诊断，治疗或手术期间固定到患者的装置，特别是在MRI诊断期间。该装置包括至少一个固定销，其由用于固定到患者的非磁性导电材料制成，以及用于支撑所述固定销的至少一个销支撑构件。绝缘装置被布置成限制所述销支撑构件和固定销之间的电耦合。所述绝缘装置是套筒形的并且布置成至少部分地围绕所述固定销。本发明还涉及绝缘装置，销支撑构件以及用于组装固定装置的方法。

8. 发明申请

WO2002076267A1 ADJUSTABLE BED 审中-公开
标题翻译：可调节床
公开(公告)号：WO2002076267A1
公开(公告)日：2002-10-03
申请号：PCT/SE2001/002698
申请日：2001-12-06
申请人： PROTON INDUSTRIES AB , LUNDREN, Mats , NILSSON, Bo , WALLEFORS, Fredrik , KENNERYD, Bengt , HELLUND, Pertti , ROOS, Tommy
发明人： LUNDREN, Mats , NILSSON, Bo , WALLEFORS, Fredrik , KENNERYD, Bengt , HELLUND, Pertti , ROOS, Tommy
IPC分类号： A47C20/04
CPC分类号： A61G7/015 , A47C20/041 , B60P3/39
摘要： A bed has a fixed frame section. In the frame section, there is secured a raisable back rest unit (12), a raisable leg rest unit (22) and an operating device. The operating device is intended for positional adjustment of the back rest unit (12) and the leg rest unit (22) and is placed substantially above the underside of the frame section. The operating device further includes a drive motor which is connected, on the one hand, to the frame section and, on the other hand, to both back rest unit (12) and the leg rest unit. The connection between the drive motor and the back rest unit (12) and leg rest unit (22), respectively, includes a number of linkage arms.
摘要翻译：床有一个固定的框架部分。在框架部分中，固定有可升高的靠背单元（12），可升高的腿部单元（22）和操作装置。所述操作装置用于所述靠背单元（12）和所述支脚单元（22）的位置调节，并且基本上位于所述框架部分的下侧。操作装置还包括驱动马达，其一方面连接到框架部分，另一方面连接到后靠单元（12）和支腿单元两者。驱动马达和靠背单元（12）和腿托单元（22）之间的连接分别包括多个联动臂。

9. 发明申请

WO2009017451A1 METHOD FOR MANUFACTURING A WOOD-BASED FURNITURE COMPONENT COMPRISING AN INTEGRAL SPACER 审中-公开
标题翻译：用于制造包含整体间隔件的基于木制家具组件的方法
公开(公告)号：WO2009017451A1
公开(公告)日：2009-02-05
申请号：PCT/SE2008/050885
申请日：2008-07-23
申请人： SWEDWOOD INTERNATIONAL AB , NILSSON, Bo
发明人： NILSSON, Bo
IPC分类号： B27N3/02 , A47B96/20 , B27N3/08 , B32B21/02 , B27N5/00
CPC分类号： B27N3/08 , A47B13/04 , A47B96/20 , B27N5/00 , B30B5/06 , B32B3/30 , B32B21/02 , B32B2479/00
摘要： The present invention relates to a method for manufacturing a wood-based furniture component (24). The method comprises steps in which chips (7) are distributed forming a chip mat (13), the chip mat (13) is compressed by means of a tool surface (19) comprising one or more gaps (21) for forming one or more projecting chip segments (53), forming spacers (5, 63, 71), the finish- pressed chipboard (3) is fed out and the projecting chip segments (53) of the finish-pressed chipboard (53) are joined to another furniture component structural element (3', 47, 49, 73).
摘要翻译：本发明涉及木制家具部件（24）的制造方法。该方法包括其中芯片（7）分布形成芯片垫（13）的步骤，芯片垫（13）通过包括一个或多个间隙（21）的工具表面（19）压缩，用于形成一个或多个突出的切屑段（53），形成间隔件（5,63,71），精加工的刨花板（3）被送出，精加工的刨花板（53）的突出的切屑段（53）与另一个家具部件结构元件（3'，47,49,73）。

10. 发明申请

WO2003095167A1 A CHIP BOARD AND A PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：一个芯片板及其准备工艺
公开(公告)号：WO2003095167A1
公开(公告)日：2003-11-20
申请号：PCT/IB2003/001895
申请日：2003-05-07
申请人： INTER IKEA SYSTEMS B.V. , ISAKSSON, Jan , NILSSON, Bo
发明人： ISAKSSON, Jan , NILSSON, Bo
IPC分类号： B27N3/14
CPC分类号： B27N3/14 , Y10T428/253 , Y10T428/31942 , Y10T428/31957 , Y10T428/31971 , Y10T428/31982 , Y10T428/31986 , Y10T428/31989
摘要： A chip board including an intermediary layer (1) and a layer (2) of large chips positioned on both sides of said intermediary layer. An outer layer (3) is provided on the 5 outer surface of each layer of large chips. In addition to the chips, the layers include an adhesive. The intermediary layer (1) includes a mixture of wood chips having chip fractions of a chip size of 0.1 to 20 mm, and the chips of this layer are randomly oriented. The individual chip in the layer (2) of large chips presents the following characteristics: a length of approx. 50 to approx. 130 mm, a width of approx. 4 to approx. 40 mm and a thickness of approx. 0.2 to approx. 2.0 mm. The chips within each layer (2) of large chips are all oriented in one and the same direction. As a result, a chip board is obtained which demonstrates a significantly higher E- module and stiffness in flexure than hitherto known despite a reduced consumption of material.
摘要翻译：一种芯片板，包括中间层（1）和位于所述中间层两侧的大芯片层（2）。外层（3）设置在每个大芯片层的外表面上。除了芯片之外，层包括粘合剂。中间层（1）包括具有芯片尺寸为0.1至20mm的芯片部分的木片的混合物，并且该层的芯片是随机取向的。大芯片层（2）中的单个芯片具有以下特征： 50到大约 130毫米，宽约 4到约 40毫米，厚约约 0.2〜 2.0毫米。大芯片每层（2）内的芯片均朝同一方向取向。结果，获得了尽管材料消耗减少的芯片板，其表现出比以前已知的更高的E模块和弯曲刚度。

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