专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009007785A3 STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES 审中-公开
标题翻译：稳定的非酒精泡沫药物组合物与联合动物及其用途
公开(公告)号：WO2009007785A3
公开(公告)日：2009-06-04
申请号：PCT/IB2007004683
申请日：2007-11-14
申请人： FOAMIX LTD , BERMAN TAL , TAMARKIN DOV , EINI MEIR , FRIEDMAN DORON , SCHUZ DAVID
发明人： BERMAN TAL , TAMARKIN DOV , EINI MEIR , FRIEDMAN DORON , SCHUZ DAVID
IPC分类号： A61K9/113 , A61K9/12
CPC分类号： A61K9/0014 , A61K8/046 , A61K8/39 , A61K8/731 , A61K8/86 , A61K9/1075 , A61K9/122 , A61Q7/00 , A61Q19/00
摘要： A stable non-alcoholic foamable pharmaceutical emulsion composition includes an unctuous emollient, at a concentration of about 0.5% to about 49% by weight; at least one multi-active agent; at a concentration of about 0.5% to about 15% by weight; water; an effective amount of an active pharmaceutical agent having a degree of solubility in the emulsion composition; and at least one liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition; wherein the unctuous emollient comprises a petrolatum alone or in combination with other unctuous agents; wherein the multi active agent is selected from the group consisting of (a) two or more complex emulgators wherein there is a difference of about 4 or more units between the HLB values of two of the emulgators or there is a significant difference in the chemical nature or structure of two of the emulgators; (b) a surfactant and a foam adjuvant or co surfactant, wherein the surfactant has a HLB close to the required HLB of the oil phase; (c) a surfactant and a liquid wax, wherein the surfactant has a HLB close to the required HLB of the oil phase; (d) a surfactant and a polymeric agent other than starch or a modified starch ester, wherein the surfactant has a HLB close to the required HLB of the oil phase; (e) a polymeric agent and a foam adjuvant or co surfactant, which can cooperate to stabilize the emulsion; (f) a single surfactant without a long polymeric side chain that is composed of a mixture of esters having a HLB close to the required HLB of the oil phase; combinations of any of the above, and wherein the composition is substantially flowable is stored in an pressurized container and upon release expands to form a breakable foam.
摘要翻译：稳定的非醇可发泡药物乳液组合物包含浓度为约0.5％至约49％（重量）的单一润肤剂; 至少一种多活性剂; 浓度为约0.5％至约15％重量; 水; 有效量的在乳液组合物中具有溶解度的活性药剂; 和至少一种浓度为总组合物重量的约3％至约25％的液化或压缩气体推进剂; 其中所述柔性润肤剂单独或与其它浮游剂组合包含凡士林; 其中所述多活性剂选自（a）两种或更多种复合乳化剂，其中在两个所述乳化剂的HLB值之间存在约4个或更多个单元的差异，或者化学性质存在显着差异或结构的两个emulgators; （b）表面活性剂和泡沫助剂或助表面活性剂，其中表面活性剂具有接近油相所需HLB的HLB; （c）表面活性剂和液体蜡，其中所述表面活性剂具有接近所述油相所需HLB的HLB; （d）表面活性剂和除淀粉或改性淀粉酯以外的聚合物，其中表面活性剂具有接近油相所需HLB的HLB; （e）聚合剂和泡沫助剂或助表面活性剂，其可以配合以稳定乳液; （f）不含长聚合物侧链的单一表面活性剂，其由具有接近油相所需HLB的HLB的酯的混合物组成; 并且其中组合物基本可流动的组合物储存在加压容器中并且当释放时膨胀以形成可破裂的泡沫。

2. 发明申请

WO2007054818A3 FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF 审中-公开
标题翻译：可燃性车辆及其药用组合物
公开(公告)号：WO2007054818A3
公开(公告)日：2008-10-23
申请号：PCT/IB2006003519
申请日：2006-05-09
申请人： FOAMIX LTD , TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX
发明人： TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX
IPC分类号： A61K9/12 , A61K47/10 , A61K47/38
CPC分类号： A61K9/122 , A61K8/046 , A61K8/39 , A61K8/60 , A61K8/988 , A61K9/0014 , A61K9/7015 , A61K47/26 , A61K47/38 , A61Q19/00 , Y10S514/945
摘要： A hygroscopic pharmaceutical composition includes at least one hygroscopic substance at a concentration sufficient to provide an Aw value of at least 0.9 and an antiinfective agent. A foamble pharmaceutical carrier includes about 50% to about 98% of a polar solvent selected from the group consisting of a polyol and PEG; 0% to about 48% of a secondary polar solvent; about 0.2% to about 5% by weight of a surface-active agent; about 0.01% to about 5% by weight of at least one polymeric agent; and a liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition.
摘要翻译：吸湿性药物组合物包括至少一种浓度足以提供至少0.9的Aw值的吸湿物质和抗感染剂。起泡药物载体包括约50％至约98％的选自多元醇和PEG的极性溶剂; 0％至约48％的第二极性溶剂; 约0.2重量％至约5重量％的表面活性剂; 约0.01重量％至约5重量％的至少一种聚合物; 和以总组合物重量计约3％至约25％浓度的液化或压缩气体推进剂。

3. 发明申请

WO2007119099A3 APPARATUS AND METHOD FOR RELEASING A MEASURE OF CONTENT FROM A PLURALITY OF CONTAINERS 审中-公开
标题翻译：释放大量容器内容的测量装置和方法
公开(公告)号：WO2007119099A3
公开(公告)日：2008-05-02
申请号：PCT/IB2006003705
申请日：2006-09-12
申请人： FOAMIX LTD , EINI MEIR , FRIEDMAN DORON , TAMARKIN DOV , SCHUZ DAVID
发明人： EINI MEIR , FRIEDMAN DORON , TAMARKIN DOV , SCHUZ DAVID
IPC分类号： B65D83/68 , B67D7/70
CPC分类号： B65D83/68 , B05B11/3084
摘要： A dispenser head for use with a plurality of containers, each of the containers having a hollow stem through which contents are dispensed when the stem is activated, includes (a) a flow guide structured and positioned to receive a plurality of pressurized containers; (b) a plurality of flow conduits disposed within the flow guide, each of the plurality of flow conduits comprising an inlet and an outlet and each said inlet capable of engagement with a respective container stem; and (c) an actuator connected to the flow guide, wherein the actuator is structured and positioned to allow simultaneous flow communication between each of the plurality of flow conduits and a respective hollow stem, allowing substantially contemporaneously dispensing and/or combining of the content from a plurality of containers.
摘要翻译：一种用于多个容器的分配器头，每个容器具有中空杆，当所述杆被致动时通过所述中空杆分配内装物，所述分配头包括：（a）构造并定位成容纳多个加压容器的流动引导件; （b）设置在所述流动引导件内的多个流动管道，所述多个流动管道中的每一个包括入口和出口，并且每个所述入口能够与相应的容器杆接合; 和（c）连接到流动引导件的致动器，其中所述致动器被构造和定位成允许所述多个流动管道中的每一个与相应的中空杆之间的同时流动连通，从而允许基本上同时分配和/或组合所述内容物多个容器。

4. 发明申请

WO2006003481A2 OLEAGINOUS PHARMACEUTICAL AND COSMETIC FOAM 审中-公开
标题翻译： OLEAGOOUS PHARMACEUTICAL和COSMETIC FOAM
公开(公告)号：WO2006003481A2
公开(公告)日：2006-01-12
申请号：PCT/IB2004004464
申请日：2004-12-16
申请人： FOAMIX LTD , TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX
发明人： TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX
IPC分类号： A61K9/00 , A61L9/04 , A61Q90/00
CPC分类号： A61K9/122 , A01N25/16 , A61K8/046 , A61K9/0034 , A61K9/107 , A61K9/12 , A61K31/351 , A61K31/436 , A61K31/496 , A61K31/522 , A61K31/573 , A61K38/13 , A61K47/10 , A61K47/14 , A61Q19/00
摘要： The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes at least one solvent selected from the group consisting of: a hydrophobic solvent, a silicone oil, an emollient, a co-solvent, and mixtures thereof, wherein the solvent is present at a concentration of about 70% to about 96.5% by weight of the total composition, at least a non-ionic surface-active agent at a concentration of about 0.1 % to less than about 10% by weight of the total composition; at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition; a therapeutically effective amount of at least one active agent; and at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition.
摘要翻译：本发明涉及含有某些活性剂的稳定的含油化妆品或治疗性泡沫组合物，具有独特的治疗性质和使用这种组合物的治疗方法。可发泡组合物包括选自以下的至少一种溶剂：疏水性溶剂，硅油，软化剂，助溶剂及其混合物，其中溶剂的浓度为约70％至约96.5 至少一种非离子表面活性剂，其浓度为总组合物重量的约0.1％至小于约10％; 浓度为总组合物重量的约0.1％至约5％的至少一种胶凝剂; 治疗有效量的至少一种活性剂; 和至少一种液化或压缩气体推进剂，其浓度为总组合物重量的约3％至约25％。

5. 发明申请

WO2009072007A3 CARRIERS, FORMULATIONS, METHODS FOR FORMULATING UNSTABLE ACTIVE AGENTS FOR EXTERNAL APPLICATION AND USES THEREOF 审中-公开
标题翻译：载体，配方，用于配制用于外用药物的不稳定活性剂的方法及其用途
公开(公告)号：WO2009072007A3
公开(公告)日：2009-11-12
申请号：PCT/IB2008003932
申请日：2008-12-08
申请人： FOAMIX LTD , TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX , SHIFRIN HELEN
发明人： TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX , SHIFRIN HELEN
IPC分类号： A61K9/12 , A61K8/04 , A61K31/65 , A61K47/06 , A61K47/14 , A61P31/04
CPC分类号： A61K9/12 , A61K8/046 , A61K9/0014 , A61K9/122 , A61K31/20 , A61K31/355 , A61K31/522 , A61K31/59 , A61K31/65 , A61K31/7056 , A61K45/06 , A61K47/06 , A61K47/14 , A61K47/24 , A61K47/34 , A61K47/44 , Y10S514/871 , Y10S514/945
摘要： The present disclosure teaches unique formulations for topical administration of tetracycline antibiotics, in which the tetracycline antibiotics remain stable.
摘要翻译：本公开教导了用于局部施用四环素抗生素的独特制剂，其中四环素抗生素保持稳定。

6. 发明申请

WO2007085902A3 FOAMABLE COMPOSITION COMBINING A POLAR SOLVENT AND A HYDROPHOBIC CARRIER 审中-公开
标题翻译：组合极性溶剂和疏水性载体的可发泡组合物
公开(公告)号：WO2007085902A3
公开(公告)日：2007-11-29
申请号：PCT/IB2006004119
申请日：2006-07-19
申请人： FOAMIX LTD , TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX
发明人： TAMARKIN DOV , FRIEDMAN DORON , EINI MEIR , BESONOV ALEX
IPC分类号： A61K9/12 , A61K8/04 , A61K9/107
CPC分类号： A61K8/046 , A61K8/31 , A61K8/34 , A61K8/345 , A61K8/361 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/46 , A61K8/4913 , A61K8/4973 , A61K8/86 , A61K8/891 , A61K8/922 , A61K8/925 , A61K9/122 , A61Q19/00
摘要： The present invention relates to a foamable vehicle or cosmetic or pharmaceutical composition, comprising: (1) an organic carrier, at a concentration of 10% to 70% by weight, wherein said organic carrier concurrently comprises: (i) at least one hydrophobic organic carrier, and (ii) at least one polar solvent; (2) at least one surface-active agent; (3) water; and (4) at least one liquefied or compressed gas propellant at a concentration of 3% to 25% by weight of the total composition. The present invention further provides a method of treating, alleviating or preventing a disorder of mammalian subject, comprising administering the above-mentioned compositions to an afflicted target site.
摘要翻译：本发明涉及可发泡载体或化妆品或药物组合物，其包含：（1）浓度为10重量％至70重量％的有机载体，其中所述有机载体同时包含：（i）至少一种疏水有机载体，和（ii）至少一种极性溶剂; （2）至少一种表面活性剂; （3）水; 和（4）至少一种浓度为全部组合物的3重量％至25重量％的液化或压缩气体推进剂。本发明进一步提供了治疗，缓解或预防哺乳动物受试者病症的方法，其包括将上述组合物施用于患病目标部位。

7. 发明申请

WO2007099396A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF 审中-公开
标题翻译：抗生物工具包及其组合物及其用途
公开(公告)号：WO2007099396A2
公开(公告)日：2007-09-07
申请号：PCT/IB2006003975
申请日：2006-06-07
申请人： FOAMIX LTD , FRIEDMAN DORON , BESONOV ALEX , TAMARKIN DOV , EINI MEIR
发明人： FRIEDMAN DORON , BESONOV ALEX , TAMARKIN DOV , EINI MEIR
CPC分类号： A61K9/122 , A61K9/0014 , A61K9/107
摘要： The present invention relates to a therapeutic kit to provide a safe and effective dosage of an antibiotic agent, including an aerosol packaging assembly including: a container accommodating a pressurized product; and an outlet capable of releasing the pressurized product as a foam, wherein the pressurized product comprises a foamable composition including: an antibiotic agent; at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, an organic polar solvent, an emollient and mixtures thereof, at a concentration of about 2 % to about 50 % by weight, a surface- active agent, about 0.01 % to about 5 % by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent, water; and liquefied or compressed gas propellant at a concentration of about 3 % to about 25 % by weight of the total composition.
摘要翻译：本发明涉及提供安全有效剂量的抗生素的治疗试剂盒，其包括气溶胶包装组件，其包括：容纳加压产品的容器; 以及能够释放作为泡沫的加压产品的出口，其中所述加压产品包括可发泡组合物，其包含：抗生素; 选自浓度为约2％至约50％重量的至少一种选自疏水性有机载体，有机极性溶剂，软化剂及其混合物的有机载体，表面活性剂，约0.01％至约5重量％的至少一种选自生物粘合剂，胶凝剂，成膜剂和相变剂的聚合物添加剂，水; 和液化或压缩气体推进剂，其浓度为总组合物重量的约3％至约25％。

8. 发明申请

WO2007007208A3 NONSTEROIDAL IMMUNOMODULATING KIT AND COMPOSITION AND USES THEREOF 审中-公开
标题翻译：非间质免疫调节试剂盒及组合物及其用途
公开(公告)号：WO2007007208A3
公开(公告)日：2007-08-30
申请号：PCT/IB2006002755
申请日：2006-03-10
申请人： FOAMIX LTD , TAMARKIN DOV , EINI MEIR , FRIEDMAN DORON
发明人： TAMARKIN DOV , EINI MEIR , FRIEDMAN DORON
IPC分类号： A61K9/12 , A61K8/04 , A61K8/67 , A61K31/07 , A61K31/203 , A61L9/04 , A61M11/00 , A61Q19/00
CPC分类号： A61K9/122 , A61K8/046 , A61K8/671 , A61K9/0014 , A61K9/10 , A61K31/07 , A61K31/203 , A61Q19/00
摘要： A composition and therapeutic kit including an aerosol packaging assembly including a container accommodating a pressurized product and an outlet capable of releasing a foamable composition, including a nonsteroidal immunomodulating agent as a foam. The foamable composition includes: i. a nonsteroidal immunomodulating agent; ii. at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, a polar solvent, an emollient and mixtures thereof, at a concentration of about 2% to about 50% by weight; iii. a surface-active agent; iv. about 0.1 % to about 5% by weight of a therapeutically active foam adjuvant, selected from the group consisting of a fatty alcohol, a fatty acid, a hydroxyl fatty acid; and mixtures thereof; v. about 0.01 % to about 5% by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent; vi. water; and vii. liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition.
摘要翻译：一种组合物和治疗套件，其包括气雾剂包装组件，该气雾剂包装组件包括容纳加压产品的容器和能够释放可发泡组合物的出口，所述可发泡组合物包括作为泡沫的非甾体免疫调节剂。可发泡组合物包含：i。非甾体免疫调节剂; II。至少一种选自疏水性有机载体，极性溶剂，润肤剂及其混合物的有机载体，浓度为约2％至约50％重量; III。表面活性剂; IV。约0.1重量％至约5重量％的治疗活性泡沫佐剂，所述治疗活性泡沫佐剂选自脂肪醇，脂肪酸，羟基脂肪酸; 及其混合物; v。约0.01重量％至约5重量％的至少一种选自生物粘附剂，胶凝剂，成膜剂和相变剂的聚合物添加剂; 六。水; 和vii。液化或压缩气体推进剂，浓度为全部组合物的约3重量％至约25重量％。

9. 发明申请

WO2009098595A3 SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES 审中-公开
标题翻译：基本上不含水的可发泡油基药物和化妆品组合物及其用途
公开(公告)号：WO2009098595A3
公开(公告)日：2009-11-12
申请号：PCT/IB2009005032
申请日：2009-02-04
申请人： FOAMIX LTD , TAMARKIN DOV , FRIEDMAN DORON , ZIV ENBAL , EINI MEIR , BERMAN TAL , DANZIGER JORGE , KEYNAN RITA , SCHUZ DAVID
发明人： TAMARKIN DOV , FRIEDMAN DORON , ZIV ENBAL , EINI MEIR , BERMAN TAL , DANZIGER JORGE , KEYNAN RITA , SCHUZ DAVID
IPC分类号： A61K9/12 , A61K8/04 , A61K47/06
CPC分类号： A61K8/046 , A61K8/31 , A61K9/0014 , A61K9/107 , A61K9/122 , A61K47/06 , A61K2800/31 , A61Q19/00 , Y10S514/859
摘要： The present invention relates to stable substantially non-aqueous, non-alcoholic, non-silicone, foamable carrier compositions comprising petrolatum or mixtures thereof, at least one foam agent, at least one propellant, and with and without the addition of an active agent. The formulations may contain a solvent substantially miscible therein. The present invention further provides a method of treating, alleviating or preventing a disorder of mammalian subject in need thereof, comprising administering the above-mentioned compositions to an afflicted target site of said mammalian subject.
摘要翻译：本发明涉及包含凡士林或其混合物，至少一种泡沫剂，至少一种推进剂以及添加和不添加活性剂的稳定的基本上非水，非醇，非硅酮，可发泡载体组合物。制剂可以含有其中基本上可混溶的溶剂。本发明进一步提供了治疗，缓解或预防有需要的哺乳动物受试者病症的方法，其包括将上述组合物施用于所述哺乳动物受试者的患病靶位点。

10. 发明申请

WO2008020268A3 APPARATUS AND METHOD FOR RELEASING A MEASURED AMOUNT OF CONTENT FROM A CONTAINER 审中-公开
标题翻译：从容器中释放测量的内容物的装置和方法
公开(公告)号：WO2008020268A3
公开(公告)日：2008-08-21
申请号：PCT/IB2006004290
申请日：2006-04-18
申请人： FOAMIX LTD , EINI MEIR , TAMARKIN DOV , FRIEDMAN DORON
发明人： EINI MEIR , TAMARKIN DOV , FRIEDMAN DORON
IPC分类号： B65D83/14
CPC分类号： B65D83/36 , A45D34/04 , A45D2200/057 , A45D2200/1018 , B65D83/285 , B65D83/303 , B65D83/54
摘要： Apparatus and method for delivering a predetermined quantity of content (14) from a pressurized container include a container (10) for housing a pressurized gas (12) and a content (14); a valve (26) for releasing content from the container (10); a metering chamber (16) in fluid communication with the container (10) and the valve (26) and having an upper wall and a lower wall, the metering chamber (16) defining a volume proportionate to a predetermined quantity of content (14) to be delivered; and a movable partition (28) comprising a seal (30) positioned in the chamber (16) and capable of moving from a first resting position to a second sealing position, the sealing position sealing fluid communication of the chamber (16) with the valve (26). When the valve (26) is opened to deliver content (14) from the container (10), the movable partition (28) moves from a first resting position to a second sealing position.
摘要翻译：用于从加压容器输送预定量的内容物（14）的装置和方法包括用于容纳加压气体（12）和内容物（14）的容器（10）; 用于从容器（10）释放内容物的阀（26）; 与容器（10）和阀（26）流体连通并具有上壁和下壁的计量室（16），所述计量室（16）限定与预定量的内容物成比例的容积（14）交付; 以及可移动分隔件（28），其包括定位在所述腔室（16）中并且能够从第一静止位置移动到第二密封位置的密封件（30），所述密封位置密封所述腔室（16）与所述阀（26）。当阀（26）打开以从容器（10）输送内容物（14）时，可移动分隔件（28）从第一静止位置移动到第二密封位置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式