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    • 1. 发明申请
    • CYCLIC DIPEPTIDES AS FEEDSTUFF ADDITIVES
    • 环二肽作为饲料添加剂
    • WO2011147881A3
    • 2012-05-24
    • PCT/EP2011058577
    • 2011-05-25
    • EVONIK DEGUSSA GMBHKOBLER CHRISTOPHHAEUSSNER THOMASWECKBECKER CHRISTOPH
    • KOBLER CHRISTOPHHAEUSSNER THOMASWECKBECKER CHRISTOPH
    • C07D241/08A23K1/16
    • C07D241/08A23K20/105A23K20/147A23K50/10A23K50/80
    • The invention relates to feedstuff additives, containing at least one diketopiperazine having the following general formula (IV), or a salt thereof, where R1 and R2 independently of each other are an amino acid residue R (preferably in the L configuration), selected from the group consisting of methionine (R = - (CH2) 2SCH3), lysine (R = -(CH2)4NH2), threonine (R = -CH (OH) (CH3)), tryptophan (R = -indolyl), histidine (R = -imidazoyl), valine (R = -CH(CH3)2), leucine (R = -CH2CH ( (CH3) 2), isoleucine (R = -CH (CH3) CH2CH3), phenylalanine (R = -CH2Ph), arginine (R = - (CH2) 3NHC (=NH) CH2), cysteine (R = -CH2SH), wherein optionally R1 can be equal to R2; or containing at least one compound having the following general formula (V), or a salt thereof, where R1 and R2 are as defined above; and to the diketopiperazine itself and to a method for producing same.
    • 本发明涉及一种饲料,其包含具有以下通式的至少二酮哌嗪的添加剂(IV)或选自甲硫氨酸(或其盐,其中R1和R2独立地为氨基酸残基,R表示(优选的L构型)R = - (CH 2 )2 SCH 3),赖氨酸(R = - (CH 2)4 NH 2),苏氨酸(R = -CH(OH)(CH 3)),色氨酸(R =吲哚基),组氨酸(R = -imidazoyl),缬氨酸(R = - CH(CH3)2),亮氨酸(R = -CH 2 CH((CH 3)2),异亮氨酸(R = -CH(CH 3)CH 2 CH 3),苯丙氨酸(R = -CH 2 PH),精氨酸(R = - ((CH 2)3 NHC = NH)CH 2),半胱氨酸(R = -CH 2 SH),其中任选R 1可以是等于R2;或者其包含具有下述通式(V)的化合物或其盐,其中R1和R2如上所定义的至少一种化合物;以及 该哌嗪本身及其制造方法。