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1. 发明申请

WO2013055515A1 METHODS AND DEVICES FOR MANIPULATING TISSUE IN VIVO 审中-公开
标题翻译：用于在体液中操作组织的方法和装置
公开(公告)号：WO2013055515A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/056890
申请日：2012-09-24
申请人： ETHICON ENDO-SURGERY, INC. , NOBIS, Rudolph H. , TRUSTY, Robert M. , SPIVEY, James T. , HESS, Christopher J. , VAKHARIA, Omar J. , PARK, Per Ola
发明人： NOBIS, Rudolph H. , TRUSTY, Robert M. , SPIVEY, James T. , HESS, Christopher J. , VAKHARIA, Omar J. , PARK, Per Ola
IPC分类号： A61B17/29 , A61B17/00 , A61B17/072
CPC分类号： A61B17/29 , A61B17/07207 , A61B2017/00473 , A61B2017/00477
摘要： Methods and devices are provided for manipulating tissue in a body cavity, i.e., in vivo. In general, the methods and devices allow an end effector to engage tissue, be detached from a shaft used to control the end effector (380) to engage the tissue, and then be moved to another location in the body cavity by a separate component, such as an external control unit. In some embodiments the end effector can include one or more deployable hooks (382) that allow the end effector to remain at a surgical site independent of any shafts or external control units. Still further, in other embodiments the end effector can include a transverse bore (484) to allow a second shaft (422) to connect to the end effector to manipulate the tissue. Additional exemplary devices, kits, and methods related to manipulating tissue in vivo are also provided.
摘要翻译：提供了用于操作体腔中的组织，即体内的方法和装置。通常，方法和装置允许端部执行器接合组织，从用于控制末端执行器（380）的轴分离以接合组织，然后通过单独的部件移动到体腔中的另一位置，例如外部控制单元。在一些实施例中，末端执行器可以包括一个或多个可展开的钩（382），其允许末端执行器独立于任何轴或外部控制单元而保持在手术位置。此外，在其他实施例中，端部执行器可以包括横向孔（484），以允许第二轴（422）连接到端部执行器以操纵组织。还提供了与在体内操作组织相关的附加的示例性装置，试剂盒和方法。

2. 发明申请

WO2013048953A1 METHODS AND DEVICES FOR REMOTELY CONTROLLING MOVEMENT OF SURGICAL TOOLS 审中-公开
标题翻译：用于远程控制外科手术运动的方法和装置
公开(公告)号：WO2013048953A1
公开(公告)日：2013-04-04
申请号：PCT/US2012/056867
申请日：2012-09-24
申请人： ETHICON ENDO-SURGERY, INC. , STOKES, Michael J. , PLESCIA, David N. , STEFANCHIK, David , VAKHARIA, Omar J. , YOO, Andrew , SPIVEY, James T. , HESS, Christopher J.
发明人： STOKES, Michael J. , PLESCIA, David N. , STEFANCHIK, David , VAKHARIA, Omar J. , YOO, Andrew , SPIVEY, James T. , HESS, Christopher J.
IPC分类号： A61B19/00
CPC分类号： A61B34/37 , A61B34/30 , A61B34/70 , A61B2017/00022 , A61B2017/00207
摘要： Methods and devices are provided for controlling movement of a distal end of a surgical instrument. In general, the methods and devices can allow for controlling movement of surgical tools, and in particular for causing mimicked motion between an external control unit and a surgical tool positioned within a patient's body. In one embodiment, a surgical system is provided having a master assembly including an input tool and a slave assembly including a surgical instrument. The master assembly and the slave assembly can be configured to be electronically coupled together such that movement of the master assembly can be electronically communicated to the slave assembly to cause mimicked movement of the slave assembly.
摘要翻译：提供了用于控制手术器械的远端的运动的方法和装置。通常，所述方法和装置可以允许控制手术工具的移动，并且特别是用于在外部控制单元和位于患者体内的外科手术工具之间引起模拟的运动。在一个实施例中，提供具有主组件的外科系统，所述主组件包括输入工具和包括外科器械的从属组件。主组件和从组件可以被配置为电子耦合在一起，使得主组件的运动可以电子地传递到从组件以引起从组件的模拟运动。

3. 发明申请

WO2008128051A2 FLUORESCENT NANOPARTICLE COMPOSITIONS, METHODS, AND DEVICES 审中-公开
标题翻译：荧光纳米材料组合物，方法和装置
公开(公告)号：WO2008128051A2
公开(公告)日：2008-10-23
申请号：PCT/US2008/060045
申请日：2008-04-11
申请人： ETHICON ENDO-SURGERY, INC , VOEGELE, James W. , TRUSTY, Robert M. , GILL, Robert M. , DLUGOS, Daniel F. , MURRAY, Michael A. , HESS, Christopher J.
发明人： VOEGELE, James W. , TRUSTY, Robert M. , GILL, Robert M. , DLUGOS, Daniel F. , MURRAY, Michael A. , HESS, Christopher J.
IPC分类号： A61K49/00 , A61K41/00 , A61B1/05 , A61B1/313
CPC分类号： A61K41/0052 , A61B1/043 , A61B1/3132 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/415 , A61B5/418 , A61K49/0017 , A61K49/0093
摘要： Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect.
摘要翻译：提供使用可用作标记物，指示剂和光源的荧光纳米颗粒的各种组合物，方法和装置。荧光纳米颗粒可以由包围生物相容的外壳如二氧化硅壳的荧光团芯形成。在一个实施方案中，荧光纳米颗粒可以被递送到组织以标记组织，使得能够识别和定位组织，和/或照亮组织周围的区域。在另一个实施方案中，荧光纳米颗粒可用于装置或植入物以将装置或植入物定位在体内，指示装置或植入物的取向，和/或照亮装置或植入物周围的区域。荧光纳米颗粒也可用于提供治疗效果。

4. 发明申请

WO2013004267A1 A CATHETER, PARTICULARLY FOR DIRECTING BILIOPANCREATIC SECRETIONS 审中-公开
标题翻译：特别指导双极化分泌物的导管
公开(公告)号：WO2013004267A1
公开(公告)日：2013-01-10
申请号：PCT/EP2011/061115
申请日：2011-07-01
申请人： ETHICON ENDO-SURGERY, INC. , PASTORELLI, Alessandro , ORTIZ, Mark Steven , HESS, Christopher J. , D'ARCANGELO, Michele , DALESSANDRO, David A.
发明人： PASTORELLI, Alessandro , ORTIZ, Mark Steven , HESS, Christopher J. , D'ARCANGELO, Michele , DALESSANDRO, David A.
IPC分类号： A61F2/04 , A61F5/00
CPC分类号： A61F2/07 , A61F2/90 , A61F5/0076 , A61F2002/072 , A61F2220/0075
摘要： A catheter (11) for directing biliopancreatic secretions, the catheter (11) comprising an elongate tubular wall (17) defining an internal fluid channel (25) and extending between a proximal end portion (12) and a distal end portion (13) of the catheter (11), the proximal end portion (12) having a proximal fastening means adapted to fasten the proximal end portion (12) within a biliary tree and the distal end portion (13) having an elongate distal anchor (18) adapted to anchor the distal end portion (13) within an intestine, wherein the distal end portion (13) is T-shaped and the elongate anchor (18) extends transversally to a longitudinal direction (19) of the catheter at the distal end portion (13).
摘要翻译：一种用于引导胰腺分泌物的导管（11），所述导管（11）包括限定内部流体通道（25）并且在近端部分（12）和远端部分（13）之间延伸的细长管状壁（17）所述导管（11），所述近端部分（12）具有适于将所述近端部分（12）紧固在胆汁树内的近端紧固装置，所述远端部分（13）具有细长远端锚固件（18）将所述远端部分（13）锚定在肠内，其中所述远端部分（13）是T形的，并且所述细长锚固件（18）在所述远端部分（13）处横向延伸到所述导管的纵向方向（19））。

6. 发明申请

WO2012007047A1 A DEVICE AND METHOD FOR DIRECTING BILE FROM THE GALLBLADDER IN THE INTESTINE 审中-公开
标题翻译：用于从INTESTINE中的GALLBLADDER引导BILE的装置和方法
公开(公告)号：WO2012007047A1
公开(公告)日：2012-01-19
申请号：PCT/EP2010/060275
申请日：2010-07-16
申请人： ETHICON ENDO-SURGERY, INC. , STOKES, Michael J. , D'ARCANGELO, Michele , PASTORELLI, Alessandro , HESS, Christopher J. , ZEINER, Mark S. , ORTIZ, Mark Steven , GALVAO NETO, Manoel
发明人： STOKES, Michael J. , D'ARCANGELO, Michele , PASTORELLI, Alessandro , HESS, Christopher J. , ZEINER, Mark S. , ORTIZ, Mark Steven , GALVAO NETO, Manoel
IPC分类号： A61B17/11 , A61F5/00 , A61M39/24
CPC分类号： A61B17/1114 , A61B2017/0649 , A61B2017/1139 , A61F5/0076 , A61M27/002 , A61M39/24
摘要： A device (11) for diverting bile from a gall bladder (8) to a portion of an intestine (3,4,5) comprises a first portion (12) adapted to be attached to a first lumen (13) of the biliary tree and gallbladder (7, 8), a second portion (14) adapted to be attached to second lumen (15) of a portion of intestine (3,4,5), a bile conduit portion (16) connected with at least one of the first (12) and second portion (14) and adapted to define a flow path between the first lumen (13) and the second lumen (15), a unidirectional valve (17) arranged in the flow path of the bile conduit portion (16) and adapted to prevent a flow from the second lumen (15) to the first lumen (13).
摘要翻译：用于将胆汁从胆囊（8）转移到肠（3,4,5）的一部分的装置（11）包括适于附接到胆道的第一内腔（13）的第一部分（12）和胆囊（7,8），适于附接到一部分肠（3,4,5）的第二腔（15）的第二部分（14），胆管导管部分（16），其与至少一个肠所述第一部分（12）和第二部分（14）并且适于限定所述第一管腔（13）和所述第二管腔（15）之间的流动路径;布置在所述胆管导管部分的流动路径中的单向阀（17） 16）并且适于防止从第二内腔（15）流到第一管腔（13）。

7. 发明申请

WO2013004264A1 A METHOD AND DEVICE FOR CREATING AN ALTERNATIVE BILE FLOW PATH 审中-公开
标题翻译：一种用于创建替代性流动路径的方法和装置
公开(公告)号：WO2013004264A1
公开(公告)日：2013-01-10
申请号：PCT/EP2011/061107
申请日：2011-07-01
申请人： ETHICON ENDO-SURGERY, INC. , PASTORELLI, Alessandro , HESS, Christopher J. , ORTIZ, Mark Steven
发明人： PASTORELLI, Alessandro , HESS, Christopher J. , ORTIZ, Mark Steven
IPC分类号： A61F2/04 , A61B17/11 , A61B17/00 , A61F5/00
CPC分类号： A61F2/04 , A61B17/0487 , A61B17/1114 , A61B2017/00818 , A61B2017/00867 , A61B2017/00876 , A61B2017/0417 , A61B2017/1103 , A61B2017/1135 , A61F2002/041
摘要： The present invention relates, in general, to devices and methods for surgically influencing the digestion of a patient with the aim to treat metabolic disorders, such as morbid obesity, related co-morbidities such as diabetes, heart disease, stroke, pulmonary disease, neoplastic diseases and accidents. In particular, the invention comprises a method for diverting biliary fluid from a biliary fluid flow path by putting into flow communication a selected location of the biliary tree to a selected location of the intestine distal to a duodenal papilla of Vater, the method comprising the steps of: - accessing endoluminally a portion of the gastrointestinal tract of a patient with an endoscope device; - gaining visual access of the abdominal cavity of the patient; - accessing transluminal the abdominal cavity; - creating a connection between a selected location of the biliary tree and a selected location of the intestine; - putting into flow communication the selected location of the biliary tree with the selected location of the intestine. The method provides for the use of a catheter device for putting into flow communication two target organs or of an anchoring and approximating device for approximating two target organs that must be anastomosed, as described in the application.
摘要翻译：本发明一般涉及用于手术影响患者消化的装置和方法，其目的是治疗代谢紊乱，例如病态肥胖，相关并发症如糖尿病，心脏病，中风，肺部疾病，肿瘤疾病和事故。特别地，本发明包括一种通过将胆汁树的选定位置与远端十二指肠乳头的选定位置进行流动连通而将胆汁流体从胆汁流动路径分流的方法，所述方法包括步骤 - 用内窥镜装置接近患者的胃肠道的一部分; - 获得患者腹腔的视觉通路; - 进入腹腔腹腔; - 在胆汁树的选定位置和肠的选定位置之间建立连接; - 将所选择的胆道的位置与选定的肠道位置进行流通。该方法提供使用导管装置将两个目标器官或用于近似两个必须吻合的目标器官的锚定和近似装置进行流通，如本申请所述。

8. 发明申请

WO2012007053A1 A LENGTH ADJUSTABLE CATHETER FOR DIRECTING BILIOPANCREATIC SECRETIONS 审中-公开
标题翻译：一种用于指导双极化分泌物的长度可调节导管
公开(公告)号：WO2012007053A1
公开(公告)日：2012-01-19
申请号：PCT/EP2010/060294
申请日：2010-07-16
申请人： ETHICON ENDO-SURGERY, INC. , ZEINER, Mark S. , ALBRECHT, Thomas Edward , ORTIZ, Mark Steven , D'ARCANGELO, Michele , PASTORELLI, Alessandro , STOKES, Michael J. , HESS, Christopher J.
发明人： ZEINER, Mark S. , ALBRECHT, Thomas Edward , ORTIZ, Mark Steven , D'ARCANGELO, Michele , PASTORELLI, Alessandro , STOKES, Michael J. , HESS, Christopher J.
IPC分类号： A61F5/00
CPC分类号： A61F5/0076 , A61M27/002 , A61M2025/0175
摘要： A catheter (11) for directing biliopancreatic secretions comprises a first flexible tube (12) having a first longitudinal axis, the first flexible tube (12) having a wall and first outlet holes (13) formed in the wall, and a second flexible tube (14) having a second longitudinal axis substantially parallel to the first longitudinal axis, wherein one of the first and second flexible tube is slidingly translatable within the other one of the first and second flexible tube.
摘要翻译：用于引导胰液分泌物的导管（11）包括具有第一纵向轴线的第一柔性管（12），所述第一柔性管（12）具有壁和形成在所述壁中的第一出口孔（13）和第二柔性管（14）具有基本上平行于所述第一纵向轴线的第二纵向轴线，其中所述第一和第二柔性管中的一个在所述第一和第二柔性管的另一个之间滑动地平移。

9. 发明申请

WO2012007044A1 A DEVICE FOR TRANSLUMENAL DIVERSION OF BILE 审中-公开
标题翻译：一个用于双向转换的设备
公开(公告)号：WO2012007044A1
公开(公告)日：2012-01-19
申请号：PCT/EP2010/060268
申请日：2010-07-16
申请人： ETHICON ENDO-SURGERY, INC. , PASTORELLI, Alessandro , HESS, Christopher J. , ORTIZ, Mark Steven , BILOTTI, Federico , AREZZO, Alberto
发明人： PASTORELLI, Alessandro , HESS, Christopher J. , ORTIZ, Mark Steven , BILOTTI, Federico , AREZZO, Alberto
IPC分类号： A61F2/04
CPC分类号： A61B17/1114 , A61B17/08 , A61B17/10 , A61B17/115 , A61B2017/00557 , A61B2017/00818 , A61B2017/00986 , A61B2017/1135 , A61B2017/1139 , A61B2017/22054 , A61B2017/22069 , A61F2002/041
摘要： A device (6) for diverting biliary fluid comprises a catheter (13) and an anastomotic coupler (32) connected to the catheter (13), the anastomotic coupler (32) having an expandable first compression portion (33) and an expandable second compression portion (34) adapted to clamp a first portion (17) of a hollow organ and a target portion (18) of the intestine to each other to cause anastomosis of the first portion (17) and the target portion (18), thereby immobilizing the catheter (13) with respect to the anastomosis.
摘要翻译：用于转移胆汁的装置（6）包括连接到导管（13）的导管（13）和吻合器（32），所述吻合联接器（32）具有可扩张的第一压缩部分（33）和可扩张的第二压缩适于将中空器官的第一部分（17）和肠的目标部分（18）彼此夹紧以使第一部分（17）和目标部分（18）吻合的部分（34），从而固定导管（13）相对于吻合。

10. 发明申请

WO2008082955A2 SUTURE ANCHORING SYSTEM 审中-公开
标题翻译： SUTURE锚固系统
公开(公告)号：WO2008082955A2
公开(公告)日：2008-07-10
申请号：PCT/US2007/087933
申请日：2007-12-18
申请人： ETHICON ENDO-SURGERY, INC , WEISENBURGH, II, William Bruce , CROPPER, Michael S. , GILL, Robert P. , MARTIN, David T. , HESS, Christopher J. , VOEGELE, James W.
发明人： WEISENBURGH, II, William Bruce , CROPPER, Michael S. , GILL, Robert P. , MARTIN, David T. , HESS, Christopher J. , VOEGELE, James W.
IPC分类号： A61B17/04 , A61B17/064 , A61B17/06 , A61B17/00
CPC分类号： A61B17/0401 , A61B17/06004 , A61B2017/00004 , A61B2017/00526 , A61B2017/0403 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0458 , A61B2017/06052 , A61B2017/06057
摘要： A first extruded member in joined to a molded member to form an integrated component. In one exemplary form, a surgical anchor is overmolded onto the end of an extruded suture to form a suture/anchor system.
摘要翻译：第一挤压构件，其连接到模制构件以形成集成部件。在一个示例性形式中，手术锚固件被包覆模制到挤压缝合线的端部上以形成缝线/锚定系统。

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