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1. 发明申请

WO2011089561A1 METHODS FOR PRODUCING AMINO-SUBSTITUTED GLYCOLIPID COMPOUNDS 审中-公开
标题翻译：制备氨基取代的甘氨酸化合物的方法
公开(公告)号：WO2011089561A1
公开(公告)日：2011-07-28
申请号：PCT/IB2011/050258
申请日：2011-01-20
申请人： Danisco A/S , SPARSØ, Flemming, Vang , KRAGH, Karsten, Matthias , WIEBE, Lars , MIKKELSEN, Rene , KJÆRSGAARD LAURSEN, Anne, Katherine
发明人： SPARSØ, Flemming, Vang , KRAGH, Karsten, Matthias , WIEBE, Lars , MIKKELSEN, Rene , KJÆRSGAARD LAURSEN, Anne, Katherine
IPC分类号： C07H5/06 , C07H15/06 , A23L1/09 , A61K31/7032 , C11D1/66 , A61P31/00
CPC分类号： C07H5/06 , A23K20/105 , A23K20/189 , A23L29/03 , A23L29/10 , A23L33/10 , A23L33/17 , A23L33/21 , A61K8/60 , A61K2800/524 , A61Q19/00 , C07H15/06 , C11D1/42 , C11D1/525 , C11D1/662 , C11D3/227 , C11D3/48 , C11D7/329
摘要： A method of preparing a compound of formula (I): wherein: a first group selected from R 1 , R 2 and R 3 is an amino- or N-acylamino monosaccharide moiety, the acyl group having 1 to 6 carbon atoms, or an oligosaccharide chain comprising 2 to 4 monosaccharide moieties, at least one of which is an amino- or N-acylamino monosaccharide moiety; a second group selected from R 1 , R 2 and R 3 is a saturated or unsaturated acyi group having 3 to 40 carbon atoms; and a third group selected from R 1 , R 2 and R 3 is hydrogen, the method comprising contacting a monoacylglycerol, the acyl moiety thereof being a saturated or unsaturated acyl group having 3 to 40 carbon atoms, or an activated derivative thereof, with a source of amino- or N-acylamino monosaccharide moiety, or an activated derivative thereof, and, if required, a source of unsubstituted monosaccharide moiety, or an activated derivative thereof, optionally in the presence of a suitable catalyst or activating agent, is described. Novel compounds, as well as In situ methods for producing the compounds,, and their use as emulsifiers, surfactants and antimicrobial agents, particularly in foodstuffs and detergent compositions, are also described.
摘要翻译：一种制备式（I）化合物的方法：其中：选自R 1，R 2和R 3的第一基团是氨基或N-酰基氨基单糖部分，具有1至6个碳原子的酰基或包含 2至4个单糖部分，其中至少一个是氨基或N-酰基氨基单糖部分; 选自R1，R2和R3的第二个基团是具有3-40个碳原子的饱和或不饱和的亚氨基; 并且选自R 1，R 2和R 3的第三基团是氢，所述方法包括使具有3-40个碳原子的饱和或不饱和酰基的酰基部分或其活化衍生物与单酰基甘油与氨基来源 - 或N-酰基氨基单糖部分或其活化衍生物，并且如果需要，可任选地在合适的催化剂或活化剂存在下，描述未取代的单糖部分源或其活化衍生物。还描述了新颖的化合物，以及用于生产化合物的原位方法，以及它们在乳化剂，表面活性剂和抗微生物剂中的用途，特别是在食品和洗涤剂组合物中的用途。

2. 发明申请

WO2011021107A9 PROCESS 审中-公开
公开(公告)号：WO2011021107A9
公开(公告)日：2011-02-24
申请号：PCT/IB2010/002992
申请日：2010-08-19
申请人： DANISCO A/S , WIEBE, Lars , SCHMIDT, Thomas
发明人： WIEBE, Lars , SCHMIDT, Thomas
摘要： There is provided a process for the preparation of a compound having the formula (I) wherein R 1 , R 2 and R 3 are independently selected from hydrogen and acyl groups, wherein at least one of R 1 , R 2 and R 3 is a branched chain long acyl group of the formula (II) wherein n is from 9 to 21 and m is 2n, and wherein p is from 0 to 4 wherein the other of R 1 , R 2 and R 3 are selected from short acyl groups of the formula (III) wherein q is from 0 to 4 the process comprising the steps of: (1 ) providing an unsaturated compound having the formula (I) wherein R 1 , R 2 and R 3 are independently selected from (a) hydrogen, (b) unsaturated long acyl group of the formula (IV) wherein x is from 0 to 3, and wherein n is from 9 to 21 and m is 2n-1-x, 2n-3-x or 2n-5-x;and (c) short acyl groups of the formula (III) wherein q is from 0 to 4 wherein at least one of R 1 , R 2 and R 3 is an unsaturated long acyl group; and (2) if at least one of R 1 , R 2 and R 3 is hydrogen, optionally acylating the compound; and (3a) (i) hydroxylating the unsaturated long acyl group, to provide a hydroxy long acyl group of the formula (V) wherein y is from 1 to 4, n is from 9 to 21 and m is 2n+1-y, 2n-1-y or 2n-3-y, and (ii) acylating the hydroxy long acyl group to provide a branched long acyl group of the formula (VI) wherein z is from 1 to 4, n is from 9 to 21 and m is 2n+1-z, 2n-1-z or 2n-3-z, and wherein p is from 0 to 4; or (3b) reacting the unsaturated long acyl group with a carboxylic acid of the formula (VII) to provide a branched long acyl group of the formula (VI) wherein z is from 1 to 4, n is from 9 to 21 and m is 2n+1-z, 2n-1-z or 2n-3-z, and wherein p is from 0 to 4.

3. 发明申请

WO2006046140A3 PROCESS FOR THE PREPARATION OF LACTONES 审中-公开
公开(公告)号：WO2006046140A3
公开(公告)日：2006-05-04
申请号：PCT/IB2005/003436
申请日：2005-10-25
申请人： DANISCO A/S , WIEBE, Lars , SCHMIDT, Thomas
发明人： WIEBE, Lars , SCHMIDT, Thomas
IPC分类号： C07D315/00
摘要： The present invention relates to a process for preparing a lactone. The process comprises the steps of reacting an aldehyde with an organic halide in a carbon chain extension reaction to form an alcohol compound comprising a functional group capable of allowing for carbonylation of said alcohol compound, and then reacting said alcohol compound in a carbonylation reaction to form an hydroxycarboxylic acid; and cyclising the hydroxycarboxylic acid to produce the lactone.

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