专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012078741A2 NOVEL FUNGAL ESTERASES 审中-公开
标题翻译：新鲜真菌
公开(公告)号：WO2012078741A2
公开(公告)日：2012-06-14
申请号：PCT/US2011063716
申请日：2011-12-07
申请人： DYADIC INTERNAT USA INC , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
发明人： VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
IPC分类号： C12N15/55 , C07K19/00 , C12N9/16 , C12N15/62 , C12N15/63
CPC分类号： C12N9/16 , C12Y301/01011 , C12Y301/01072 , C12Y301/01073 , C12Y301/01074 , C12Y301/01086
摘要： This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to convert lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass. The invention also relates to a method to release cellular content by degradation of cell walls. The invention also relates to methods to use the novel enzymes and compositions of such enzymes to improve the digestability of animal feed and in a variety of other processes, including food and beverage processing, baking, washing of clothing, detergent processes, biorefining, deinking and biobleaching of paper and pulp, and treatment of waste streams.
摘要翻译：本发明涉及新型酶及其生产方法。更具体地，本发明涉及各种真菌酶。描述了编码这种酶，组合物，重组和遗传修饰的宿主细胞的核酸分子和使用方法。本发明还涉及将木质纤维素生物质转化为可发酵糖的方法，其中酶可降解木质纤维素材料和酶的新组合，包括提供来自植物生物质的糖的协同释放的酶。本发明还涉及通过细胞壁降解释放细胞内容物的方法。本发明还涉及使用新型酶和这些酶的组合物来提高动物饲料和各种其它方法的消化能力的方法，包括食品和饮料加工，烘烤，洗涤衣物，洗涤剂方法，生物精炼，脱墨和纸和纸浆的生物漂白以及废物流的处理。

2. 发明申请

WO2012027374A3 NOVEL FUNGAL CARBOHYDRATE HYDROLASES 审中-公开
标题翻译：新型FUNGAL CARBOHYDRATE HYDROLASES
公开(公告)号：WO2012027374A3
公开(公告)日：2012-08-16
申请号：PCT/US2011048817
申请日：2011-08-23
申请人： DYADIC INTERNAT USA INC , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
发明人： VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
IPC分类号： C12N15/56 , A23K1/165 , C11D3/386 , C12N9/24 , C12P7/06
CPC分类号： C11D3/38636 , A21D8/042 , A23K20/189 , C12N9/2402 , C12N9/2434 , C12Y302/01055 , Y02E50/17
摘要： This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to convert lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass. The invention also relates to a method to release cellular content by degradation of cell walls. The invention also relates to methods to use the novel enzymes and compositions of such enzymes to improve digestability of animal feed and in a variety of other processes, including food and beverage processing, baking, washing of clothing, detergent processes, biorefining, deinking and biobleaching of paper and pulp, and treatment of waste streams.
摘要翻译：本发明涉及新型酶及其生产方法。更具体地，本发明涉及各种真菌酶。描述了编码这种酶，组合物，重组和遗传修饰的宿主细胞的核酸分子和使用方法。本发明还涉及将木质纤维素生物质转化为可发酵糖的方法，该酶用于降解木质纤维素材料和酶的新组合，包括提供来自植物生物质的糖的协同释放的酶。本发明还涉及通过细胞壁降解释放细胞内容物的方法。本发明还涉及使用新型酶和这些酶的组合物来改善动物饲料的消化能力和各种其它方法的方法，包括食品和饮料加工，烘烤，衣服洗涤，洗涤剂方法，生物精炼，脱墨和生物漂白的纸和纸浆，以及废物流的处理。

3. 发明申请

WO2012048334A3 NOVEL FUNGAL PROTEASES 审中-公开
标题翻译：新的真菌蛋白
公开(公告)号：WO2012048334A3
公开(公告)日：2013-01-10
申请号：PCT/US2011055703
申请日：2011-10-11
申请人： DYADIC INTERNAT USA INC , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
发明人： VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
IPC分类号： C12N9/58 , A23B4/20 , A23C19/032 , A61K38/48 , C11D3/386 , C12N15/57
CPC分类号： C12N9/58 , A23C19/0326 , A61K38/48 , C11D3/38609
摘要： This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to the degradation of protein and novel combinations of enzymes, including those that provide a synergistic release of amino acids or lower molecular weight proteins. The invention also relates to methods to use the novel enzymes and compositions of such enzymes in a variety of other processes, including washing or treating of clothing or fabrics, detergent processes, cleaning of carpets, leather treatment, animal feed, food processing, baking, increasing the protein yield of food, modification of food taste, processing of proteins in protein production, processing of beverages, medical treatment, and cosmetic treatment, and bio fuels.
摘要翻译：本发明涉及新型酶及其生产方法。更具体地，本发明涉及各种真菌酶。描述了编码这种酶，组合物，重组和遗传修饰的宿主细胞的核酸分子和使用方法。本发明还涉及降解蛋白质和酶的新型组合的方法，包括提供氨基酸或低分子量蛋白质的协同释放的酶的方法。本发明还涉及在各种其它方法中使用新型酶和这些酶的组合物的方法，包括衣物或织物的洗涤或处理，洗涤剂方法，地毯的清洁，皮革处理，动物饲料，食品加工，烘烤，增加食物的蛋白质产量，改变食物味道，蛋白质生产中的蛋白质加工，饮料加工，医疗和美容处理以及生物燃料。

4. 发明申请

WO2012068236A2 NOVEL FUNGAL OXIDOREDUCTASES 审中-公开
标题翻译：新型真菌氧化剂
公开(公告)号：WO2012068236A2
公开(公告)日：2012-05-24
申请号：PCT/US2011060970
申请日：2011-11-16
申请人： DYADIC INTERNAT USA INC , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
发明人： VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
IPC分类号： C12N15/53 , A61K38/44 , C02F3/00 , C07K14/37 , C07K16/14 , C07K19/00 , C12P7/04
CPC分类号： C07K14/37 , A61K38/00 , C12N9/0004 , C12P7/10 , C12P19/02 , C12P19/14 , C12P2203/00 , Y02E50/16
摘要： This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to enzymes of fungal origin classified as oxidoreductases and produced by fungi. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to methods to use the novel enzymes and compositions of such enzymes in a variety of other processes, including disinfection food, deinking and biobleaching of flour, cotton, paper and pulp, and the treatment of pollution. The invention also relates to a method to aid in the conversion of lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass.
摘要翻译：本发明涉及新型酶及其生产方法。更具体地，本发明涉及分类为氧化还原酶并由真菌产生的真菌来源的酶。描述了编码这种酶，组合物，重组和遗传修饰的宿主细胞的核酸分子和使用方法。本发明还涉及在各种其他方法中使用新型酶和这些酶的组合物的方法，包括消毒食品，面粉，棉花，纸和纸浆的脱墨和生物漂白以及污染的处理。本发明还涉及一种帮助将木质纤维素生物质转化为可发酵糖的方法，其中酶降解木质纤维素材料和酶的新型组合，包括提供来自植物生物质的糖的协同释放的酶。

5. 发明申请

WO2012018691A3 NOVEL FUNGAL ENZYMES 审中-公开
标题翻译：新型真菌酶
公开(公告)号：WO2012018691A3
公开(公告)日：2012-05-03
申请号：PCT/US2011045949
申请日：2011-07-29
申请人： DYADIC INTERNATIONAL INC , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
发明人： VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN , EMALFARB MARK
IPC分类号： C07H21/04 , C12N9/30 , C12N9/58
CPC分类号： C12P19/02 , A23K10/14 , A23K20/189 , A23L29/06 , C11D3/386 , C11D3/38636 , C11D3/38645 , C12N9/2402 , C12P7/10 , C12P2203/00 , C12Y302/01055 , D06L1/14 , D06L4/40 , D06M16/003 , D06P1/228 , D06P5/13 , D06P5/137 , D06P5/15 , D06P5/158 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： This invention relates to novel fungal enzymes, nucleic acid molecules encoding such enzymes, and methods for producing the same. The invention further relates to a method to convert lignocellulosic biomass to fermentable sugars with the enzymes, novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass, release of cellular content by degradation of cell walls, improve digestability of animal feed, and use of the enzymes in food and beverage processing, baking, washing of clothing, detergent processes, biorefining, deinking and biobleaching of paper and pulp, and treatment of waste streams.
摘要翻译：本发明涉及新型真菌酶，编码这些酶的核酸分子及其制备方法。本发明进一步涉及一种将木质纤维素生物质转化为酶的可发酵糖的方法，酶的新型组合，包括提供植物生物质协同释放糖，通过细胞壁降解释放细胞含量，提高动物消化能力食品和饮料加工中的酶的进料和使用，烘焙，洗涤衣物，洗涤剂方法，生物精炼，纸和纸浆的脱墨和生物漂白以及废物流的处理。

6. 发明申请

WO2012021883A3 NOVEL FUNGAL ENZYMES 审中-公开
标题翻译：新型真菌酶
公开(公告)号：WO2012021883A3
公开(公告)日：2012-05-10
申请号：PCT/US2011047734
申请日：2011-08-15
申请人： DYADIC INTERNATIONAL INC , EMALFARB MARK , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN
发明人： EMALFARB MARK , VISSER JOHANNES , HINZ SANDRA , WERIJ JAN , VISSER JACOB , JOOSTEN VIVI , KOETSIER MARTIJN
IPC分类号： C07H21/04 , C12N9/30 , C12N9/58
CPC分类号： C12N9/2402
摘要： This invention relates to novel fungal enzymes and methods for producing the same. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to convert lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes promoting the synergistic release of sugars from plant biomass. The invention also relates to a method to release cellular content by degradation of cell walls. The invention also relates to methods to use the novel enzymes and compositions of such enzymes to improve digest ability of animal feed and in a variety of other processes, including food and beverage processing, baking, washing of clothing, detergent processes, biorefining, deinking and biobleaching of paper and pulp, and treatment of waste streams.
摘要翻译：本发明涉及新颖的真菌酶及其制备方法。描述了编码这种酶，组合物，重组和遗传修饰的宿主细胞的核酸分子和使用方法。本发明还涉及将木质纤维素生物质转化成可降解木质纤维素材料的酶和促进植物生物质中糖的协同释放的酶的新组合的可发酵糖的方法。本发明还涉及通过细胞壁降解释放细胞内容物的方法。本发明还涉及使用新型酶和这些酶的组合物来提高动物饲料的消化能力和各种其它方法的方法，包括食品和饮料加工，烘烤，洗涤衣物，洗涤剂方法，生物精炼，脱墨和纸和纸浆的生物漂白以及废物流的处理。

7. 发明申请

WO2013159005A3 A METHOD OF IMPROVING THE ACTIVITY OF CELLULASE ENZYME MIXTURES IN THE SACCHARIFICATION OF (LIGNO)CELLULOSIC MATERIAL 审中-公开
标题翻译：改善（LIGNO）纤维素材料分离中纤维素酶酶混合物活性的方法
公开(公告)号：WO2013159005A3
公开(公告)日：2014-01-16
申请号：PCT/US2013037390
申请日：2013-04-19
申请人： DYADIC INTERNAT USA LTD , EMALFARB MARK , SINITSYN ARKADY , JUNDZIL RICHARD , WERY JAN , VISSER JACOB , JOOSTEN ROB , KOETSIER MARTIJN
发明人： EMALFARB MARK , SINITSYN ARKADY , JUNDZIL RICHARD , WERY JAN , VISSER JACOB , JOOSTEN ROB , KOETSIER MARTIJN
IPC分类号： C12N1/15
CPC分类号： C12N9/2437 , C12N9/0006 , C12N15/80 , C12P19/14 , C12Y101/99018
摘要： The present invention relates to modified filamentous fungal organisms having improved activity profiles with respect to the conversion of complex carbohydrates into simple sugars from cellulosic materials, including fungal organisms belonging to a genus selected from the group consisting of: Chrysosporium, Thielavia, Talaromyces, Thermomyces, Thermoascus, Neurospora, Aureobasidium, Filibasidium, Piromyces, Corynascus, Cryplococcus, Acremonium, Tolypocladium, Scytalidium, Schizophyllum, Sporotrichum, Penicillium, Gibberella, Myceliophthora, Mucor, Aspergillus, Fusarium, Humicola, Trichoderma, and Talaromyces, plus anamorphs and teleomorphs thereof. Filamentous fungal organisms having improved activity profiles are obtained by modifying genes encoding enzymes involved in the production of cellobionolactone, cellobionic acid, gluconolactone, gluconic acid, and related products, by a variety of mutagenic methods, resulting in nucleotide substitutions, insertions, and deletions, increasing the level of saccharification in enzyme mixtures obtained from the modified organisms.
摘要翻译：本发明涉及关于将复合碳水化合物转化为纤维素材料的简单糖的改进的活性谱的改良的丝状真菌生物，包括属于选自以下的属的真菌生物：Chrysosporium，Thielavia，Talaromyces，Thermomyces，嗜热链球菌，丝状芽孢杆菌，白喉菌，丝状菌属，丝状芽孢杆菌属，Corynascus，Cryplococcus，Acremonium，Tolypocladium，Scytalidium，Schizophyllum，Sporotrichum，Penicillium，Gibberella，Myceliophthora，Mucor，Aspergillus，Fusarium，Humicola，Trichoderma和Talaromyces，以及其变形和远视。通过各种诱变方法修饰参与生产纤维二糖内酯，纤维二糖酸，葡萄糖酸内酯，葡萄糖酸和相关产品的酶的基因，得到具有改善的活性谱的丝状真菌生物，得到核苷酸取代，插入和缺失，增加从改性生物获得的酶混合物中的糖化水平。

8. 发明申请

WO2010107303A3 CHRYSOSPORIUM LUCKNOWENSE PROTEIN PRODUCTION SYSTEM 审中-公开
标题翻译：木质素蛋白质蛋白质生产系统
公开(公告)号：WO2010107303A3
公开(公告)日：2010-12-16
申请号：PCT/NL2010000045
申请日：2010-03-16
申请人： DYADIC NEDERLAND B V , PUNT PETER J , BURLINGAME RICHARD PAUL , PYNNONEN CHRISTINE M , VERDOES JACOBA , OLSON PHILLIP T , WERY JAN , VISSER JOHANNES HEINRICH , EMALFARB MARK A , VISSER JACOB
发明人： PUNT PETER J , BURLINGAME RICHARD PAUL , PYNNONEN CHRISTINE M , OLSON PHILLIP T , WERY JAN , VISSER JOHANNES HEINRICH , EMALFARB MARK A , VISSER JACOB , VERDOES JAN CORMELIS
IPC分类号： C12N15/00 , C12N15/09 , C12P21/02 , C12R1/645
CPC分类号： C12N15/80 , C12N1/14 , C12N9/1205 , C12N9/2402 , C12N9/2428 , C12N9/2437 , C12N9/2442 , C12N9/248 , C12N15/01 , C12P21/02 , C12Q1/40 , C12R1/645 , C12Y302/01003 , C12Y302/01004 , C12Y302/01006 , C12Y302/01008 , C12Y302/01014 , C12Y302/01015 , C12Y302/01091 , C12Y304/21062 , C12Y304/23025 , G01N2333/93
摘要： The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20 % of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ß- glucanase and endogenous cellobiohydrolase is less than 20 % of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75 %, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed. Finally a method for simplified screening of strains functionally expressing a desired enzyme by application of said strains have been provided.
摘要翻译：本发明提供了一种新的真菌生产系统，其包含真菌宿主菌株Chrysosporium lucknowense，其中内源性纤维素酶分泌少于Chrysosporium lucknowense菌株UV18-25的内源性纤维素酶分泌的20％。优选地，内源性蛋白酶，内源性β-葡聚糖酶和内源性纤维二糖水解酶的分泌也小于Chrysosporium lucknowense菌株UV 18-25的分泌的20％。此外，提供真菌宿主菌株，其中几个基因已被破坏。根据本发明的另一方面，已经描述了用于纯化高于75％的纯蛋白质的同源和/或异源产生方法，其包括在本发明的菌株中表达编码所述蛋白质的基因。此外，已经公开了生产人造蛋白质混合物的方法，其包括在根据本发明的菌株中表达编码每种所述蛋白质的基因。已经提供了通过应用所述菌株来功能性表达所需酶的菌株的简化筛选的方法。

9. 发明申请

WO9713853A3 PROTEIN DETECTION 审中-公开
标题翻译：蛋白质检测
公开(公告)号：WO9713853A3
公开(公告)日：1997-06-19
申请号：PCT/EP9604510
申请日：1996-10-14
申请人： GIST BROCADES BV , DEN BROECK HENRIETTE CATHARINA , GRAAFF LEENDERT HENDRIK DE , VISSER JACOB , OOYEN ALBERT JOHANNES JOSEPH V
发明人： VAN DEN BROECK HENRIETTE CATHA , DE GRAAFF LEENDERT HENDRIK , VISSER JACOB , VAN OOYEN ALBERT JOHANNES JOSE
IPC分类号： C12N15/09 , C07K14/38 , C07K14/39 , C12N1/21 , C12N9/24 , C12N9/42 , C12N15/00 , C12N15/10 , C12N15/56 , C12N15/70 , C12R1/19 , C12R1/66
CPC分类号： C12N15/1086 , C12N9/2437 , C12N9/248 , C12Y302/01004 , C12Y302/01008 , C12Y302/01032 , C12Y302/01055
摘要： The present invention provides a method for identifying a DNA fragment encoding a protein of interest, wherein a cDNA library in the form of bacterial host cells transformed with DNA obtainable from an eukaryotic organism capable of producing said protein is screened for expression of said protein using a test which is indicative for its presence, characterised in that screening of the host cells is performed after the transforming DNA has become part of a plasmid. The cDNA library is preferably from an eukaryotic organism. The eukaryotic organism is preferably a fungus or a yeast cell, more preferably an Aspergillus species, most preferred is a member of the Aspergillus niger group. The enzymes screened for are preferably enzymes which show cellulase, endoxylanase or arabinoxylan degrading activity.

10. 发明申请

WO2011059329A3 PENTOSE TRANSPORTERS AND USES THEREOF 审中-公开
标题翻译： PENTOSE TRANSPORTERS及其用途
公开(公告)号：WO2011059329A3
公开(公告)日：2011-09-01
申请号：PCT/NL2010050755
申请日：2010-11-12
申请人： UNIV UTRECHT HOLDING BV , VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG , STICHTING TECH WETENSCHAPP , UNIV LEIDEN , VANKUYK PATRICIA ANN , DE VRIES RONALD PETER , VISSER JACOB , RAM ARTHUR FRANCISCUS JOHANNES , VAN DEN HONDEL CORNELIS ANTONIUS MARIA JACOBUS JOH , BATTAGLIA EVY , VIVAS DUARTE DIANA ALEXANDRA
发明人： VANKUYK PATRICIA ANN , DE VRIES RONALD PETER , VISSER JACOB , RAM ARTHUR FRANCISCUS JOHANNES , VAN DEN HONDEL CORNELIS ANTONIUS MARIA JACOBUS JOH , BATTAGLIA EVY , VIVAS DUARTE DIANA ALEXANDRA
IPC分类号： C07K14/38
CPC分类号： C07K14/38 , Y02E50/16
摘要： The invention relates to the production of biofuels, proteins, peptides and other value-added compounds from crude carbon sources. The inventors identified genes encoding novel pentose transporters, in particular transporters of L-arabinose and/or D-xylose. Regulation of the Aspergillus niger genes by xlnR and araR was instrumental in the identification of these genes and their substrate specificities. Provided are novel pentose transporters and their encoding nucleic acids. Also provided are host cells (over)expressing a transporter, and industrial applications thereof, for instance in biofuel production.
摘要翻译：本发明涉及从粗碳源生产生物燃料，蛋白质，肽和其他增值化合物。发明人确定了编码新戊糖转运蛋白的基因，特别是L-阿拉伯糖和/或D-木糖的转运蛋白。通过xlnR和araR调节黑曲霉基因有助于鉴定这些基因及其底物特异性。提供新的戊糖转运蛋白及其编码核酸。还提供了表达转运蛋白的宿主细胞（以上）及其工业应用，例如在生物燃料生产中。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式