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1. 发明申请

WO2008057463A2 PEPTIDE-BASED CONDITIONERS 审中-公开
标题翻译：基于肽的调节剂
公开(公告)号：WO2008057463A2
公开(公告)日：2008-05-15
申请号：PCT/US2007023219
申请日：2007-11-02
申请人： DU PONT , FAHNESTOCK STEPHEN R , O'BRIEN JOHN P , WANG HONG
发明人： FAHNESTOCK STEPHEN R , O'BRIEN JOHN P , WANG HONG
CPC分类号： C07K7/08 , A61K8/64 , A61K2800/94 , A61Q3/00 , A61Q5/12 , A61Q19/00 , C07K7/06 , C07K14/001 , C07K2319/01
摘要： Peptides have been identified that bind with high affinity to hair, skin, and nails. The peptide-based conditioners consist of a body surface-binding peptide coupled to a conditioning peptide. Conditioning peptides are typically derived from proteins and peptide having repeating amino acid sequences. Personal care compositions containing these peptide- based conditioners are also described.
摘要翻译：已经鉴定出以高亲和力结合头发，皮肤和指甲的肽。基于肽的调理剂由与调理肽偶联的体表面结合肽组成。调理肽通常衍生自具有重复氨基酸序列的蛋白质和肽。还描述了含有这些基于肽的调理剂的个人护理组合物。

2. 发明申请

WO2007117564A3 CLAY-BINDING PEPTIDES AND METHODS OF USE 审中-公开
标题翻译：粘合蛋白和使用方法
公开(公告)号：WO2007117564A3
公开(公告)日：2008-02-07
申请号：PCT/US2007008526
申请日：2007-04-05
申请人： DU PONT , ITTEL STEVEN DALE , CUNNINGHAM SCOTT D , ROUVIERE PIERRE E , FAHNESTOCK STEPHEN R , O'BRIEN JOHN P
发明人： ITTEL STEVEN DALE , CUNNINGHAM SCOTT D , ROUVIERE PIERRE E , FAHNESTOCK STEPHEN R , O'BRIEN JOHN P
IPC分类号： C07K7/08 , C07K14/00
CPC分类号： C07K7/06 , C07K7/08 , C07K14/001 , C07K17/14
摘要： Combinatorially generated peptides are provided that have binding affinity for clay. The peptides may be used to deliver benefit agents to various clay surfaces.
摘要翻译：提供了对粘土具有结合亲和力的组合产生的肽。肽可以用于将有益剂递送到各种粘土表面。

3. 发明申请

WO2006094093A2 A METHOD FOR IDENTIFYING SKIN CARE COMPOSITION-RESISTANT SKIN-BINDING PEPTIDES 审中-公开
标题翻译：鉴定皮肤护理组合物抗皮肤粘连肽的方法
公开(公告)号：WO2006094093A2
公开(公告)日：2006-09-08
申请号：PCT/US2006007362
申请日：2006-02-28
申请人： DU PONT , WANG HONG , WU YING , O'BRIEN JOHN P
发明人： WANG HONG , WU YING , O'BRIEN JOHN P
CPC分类号： A61K8/64 , A61K2800/57 , A61K2800/94 , A61Q1/02 , A61Q5/065 , A61Q19/00 , G01N33/6845
摘要： A method for identifying skin care composition-resistant skin-binding peptides is described. The skin care composition-resistant skin-binding peptides bind strongly to skin from a skin care composition matrix and are stable therein. Peptide-based skin benefit agents, such as skin conditioners and skin colorants, based on the skin care composition-resistant skin binding peptides are described. The peptide-based skin conditioners and skin colorants consist of skin care composition-resistant skin-binding peptide coupled to a skin conditioning agent or a coloring agent, either directly or through an optional spacer. Skin care and skin coloring product compositions comprising these peptide-based skin conditioners and colorants are also described.
摘要翻译：描述了一种鉴定皮肤护理组合物抗性皮肤结合肽的方法。皮肤护理组合物抗性皮肤结合肽从皮肤护理组合物基质强烈地与皮肤结合并且在其中是稳定的。描述了基于皮肤护理组合物抗性皮肤结合肽的基于肽的皮肤有益剂，例如皮肤调理剂和皮肤着色剂。基于肽的皮肤调理剂和皮肤着色剂由直接或通过任选的间隔物与皮肤调理剂或着色剂偶联的护肤组合物抗性皮肤结合肽组成。还描述了包含这些基于肽的皮肤调理剂和着色剂的皮肤护理和皮肤着色产品组合物。

4. 发明申请

WO2007035531A2 METHOD FOR ENHANCING THE EFFECT OF PARTICULATE BENEFIT AGENTS 审中-公开
标题翻译：提高颗粒状有益剂的效果的方法
公开(公告)号：WO2007035531A2
公开(公告)日：2007-03-29
申请号：PCT/US2006036108
申请日：2006-09-15
申请人： DU PONT , BECK WILLIAM A , O'BRIEN JOHN P , WANG HONG
发明人： BECK WILLIAM A , O'BRIEN JOHN P , WANG HONG
CPC分类号： A61K8/64 , A61K8/11 , A61K8/8111 , A61K8/8117 , A61K8/8123 , A61K8/8152 , A61K8/88 , A61Q5/02 , A61Q5/065 , A61Q5/12 , C07K7/08
摘要： A method for applying a particulate benefit agent to a body surface is provided. The method employs a particulate benefit agent coated with a polymer. The polymer-coated benefit agent is applied to a body surface such as hair or skin, in the presence of a composition comprising a peptide having affinity for the polymer. The presence of the polymer-binding peptide in the application serves to extend the binding longevity of the coated particulate benefit agent on the body surface.
摘要翻译：提供了一种用于将颗粒有益剂施用于身体表面的方法。该方法使用涂覆有聚合物的颗粒有益剂。在包含对聚合物具有亲和性的肽的组合物存在下，将聚合物涂覆的有益剂施用于身体表面如头发或皮肤。本申请中聚合物结合肽的存在用于延长涂覆的颗粒有益剂在体表上的结合寿命。

5. 发明申请

WO2006094094A2 A METHOD FOR IDENTIFYING HAIR CONDITIONER-RESISTANT HAIR-BINDING PEPTIDES AND HAIR BENEFIT AGENTS THEREFROM 审中-公开
标题翻译：用于鉴定头发耐受性头发结合肽和头发有益剂的方法
公开(公告)号：WO2006094094A2
公开(公告)日：2006-09-08
申请号：PCT/US2006007364
申请日：2006-02-28
申请人： DU PONT , WANG HONG , WU YING , O'BRIEN JOHN P
发明人： WANG HONG , WU YING , O'BRIEN JOHN P
CPC分类号： A61Q1/10 , A61K8/64 , A61Q5/065 , C07K7/06 , C07K7/08 , C07K14/001 , C12Q1/6809
摘要： A method for identifying hair conditioner-resistant hair-binding peptides is described. The hair conditioner-resistant hair-binding peptides bind strongly to hair from a hair conditioner matrix and are stable therein. Peptide-based benefit agents, such as hair conditioners and hair colorants, based on the hair conditioner-resistant hair binding peptides are described. The peptide-based hair conditioners and hair colorants consist of a hair conditioner-resistant hair-binding peptide coupled to a hair conditioning agent or a coloring agent, either directly or through an optional spacer. Hair care and hair coloring product compositions comprising these peptide-based hair conditioners and colorants are also described.
摘要翻译：描述了一种用于鉴定头发护发素抗性的头发结合肽的方法。头发护发素的头发结合肽强力地与头发调理剂基质的头发结合并且在其中是稳定的。描述了基于护发素抗性头发结合肽的基于肽的有益剂，例如头发调理剂和头发着色剂。基于肽的护发素和头发着色剂由直接或通过任选的间隔物与头发调理剂或着色剂偶联的头发护发素抗性发束结合肽组成。还描述了包含这些基于肽的头发调理剂和着色剂的头发护理和头发着色产品组合物。

6. 发明申请

WO2013036918A3 HIGH TITER PRODUCTION OF HIGHLY LINEAR POLY (alpha 1, 3 GLUCAN) 审中-公开
标题翻译：高度线性聚合物的高产（α1,3葡萄糖）
公开(公告)号：WO2013036918A3
公开(公告)日：2013-11-07
申请号：PCT/US2012054435
申请日：2012-09-10
申请人： DU PONT , O'BRIEN JOHN P , PAYNE MARK S
发明人： O'BRIEN JOHN P , PAYNE MARK S
IPC分类号： C08B37/00 , C08L5/00 , C12P19/18
CPC分类号： C12P19/18 , C08B37/0009 , C08L5/00 , C12N9/1051 , C12P19/04
摘要： A process for enzymatic preparation of a highly linear poly (alpha 1, 3 glucan) from sucrose is disclosed. The glucosyltransferase enzyme (gtfJ) from Streptococcus salivarius is used to convert sucrose to a highly linear poly (alpha 1, 3 glucan) in high titers. Hydrolyzed poly (alpha 1, 3 glucan) is used as the primer for the gtfJ enzyme reaction resulting in the formation of highly linear poly (alpha 1, 3 glucan).
摘要翻译：公开了从蔗糖酶制备高度线性的聚（α1,3葡聚糖）的方法。来自唾液链球菌的葡糖基转移酶（gtfJ）用于以高滴度将蔗糖转化为高度线性的聚（α1,3葡聚糖）。水解的聚（α1,3葡聚糖）用作gtfJ酶反应的引物，导致形成高度线性的聚（α1,3葡聚糖）。

7. 发明申请

WO2005023836A2 PEPTIDE-BASED DIBLOCK AND TRIBLOCK DISPERSANTS AND DIBLOCK POLYMERS 审中-公开
标题翻译：基于肽的二嵌段和三嵌段分散体和二嵌段聚合物
公开(公告)号：WO2005023836A2
公开(公告)日：2005-03-17
申请号：PCT/US2004029513
申请日：2004-09-08
申请人： DU PONT , O'BRIEN JOHN P , YANG JIANJUN
发明人： O'BRIEN JOHN P , YANG JIANJUN
IPC分类号： B01F17/00 , C07K7/06 , C07K7/08 , C09D5/02 , C09D7/02 , C09D11/00 , C09D11/02 , C07K
CPC分类号： C07K7/06 , B01F17/005 , B01F17/0057 , C07K7/08 , C09D5/027 , C09D7/45 , C09D11/037
摘要： Peptides have been identified that bind with high affinity to common ink pigments and to various print media, including paper and fabrics. These peptides were used to prepare diblock and triblock dispersants for coating applications, including ink jet printing, and diblock polymers for treating paper and fabrics. The diblock dispersants consist of a pigment-binding peptide coupled to a hydrophilic linker, a pigment-binding peptide coupled to a print medium-binding peptide or a print medium-binding peptide coupled to a hydrophobic linker. The diblock polymers consist of a print medium-binding peptide coupled to a hydrophilic linker or a benefit agent. The triblock dispersants consist of a pigment-binding peptide coupled to a hydrophilic linker, which is coupled to a print medium-binding peptide.
摘要翻译：已经鉴定了与常见的油墨颜料和各种印刷介质（包括纸和织物）以高亲和力结合的肽。这些肽用于制备用于涂布应用的二嵌段和三嵌段分散剂，包括喷墨印刷和用于处理纸和织物的二嵌段聚合物。二嵌段分散剂由耦合到亲水接头的颜料结合肽，偶联至印刷介质结合肽的颜料结合肽或与疏水性连接体偶联的印刷介质结合肽组成。二嵌段聚合物由与亲水接头或有益试剂偶联的印迹介质结合肽组成。三嵌段分散剂由与亲水接头偶联的颜料结合肽组成，其与印刷介质结合肽偶联。

8. 发明申请

WO2007016583A3 COLORING COMPOSITIONS WITH PEPTIDE-BASED DISPERSANTS AND BINDERS 审中-公开
标题翻译：用肽基分散剂和粘合剂着色组合物
公开(公告)号：WO2007016583A3
公开(公告)日：2007-09-07
申请号：PCT/US2006029974
申请日：2006-08-01
申请人： DU PONT , O'BRIEN JOHN P
发明人： O'BRIEN JOHN P
IPC分类号： C07K7/00
CPC分类号： C07K7/08 , C07K7/06 , C07K14/001
摘要： Coloring compositions comprising peptide-based dispersants and/or binders are provided. The compositions are particularly useful for the coloring or dyeing of substrates such as paper and textile fabrics. The peptide-based dispersant and/or binder compositions are distinguished by the presence of at least one positively charged terminal amino acid on the peptide portion of the composition which enhances binding to the substrate.
摘要翻译：提供了包含基于肽的分散剂和/或粘合剂的着色组合物。该组合物特别适用于基材如纸和织物的着色或染色。基于肽的分散剂和/或粘合剂组合物的特征在于组合物的肽部分上存在至少一个带正电荷的末端氨基酸，其增强了与底物的结合。

9. 发明申请

WO2007059076A3 PEPTIDE-BASED ORGANIC SUNSCREENS 审中-公开
标题翻译：基于肽的有机防晒霜
公开(公告)号：WO2007059076A3
公开(公告)日：2007-11-29
申请号：PCT/US2006044082
申请日：2006-11-14
申请人： DU PONT , LOWE DAVID J , O'BRIEN JOHN P , WILKINS ANTOINETTE E
发明人： LOWE DAVID J , O'BRIEN JOHN P , WILKINS ANTOINETTE E
IPC分类号： A61Q17/04 , A61K8/30 , A61K8/64 , A61K8/70 , C07K7/08
CPC分类号： A61Q17/04 , A61K8/64 , A61K2800/57 , C07K7/06 , C07K7/08
摘要： Peptide-based organic sunscreens, formed by coupling a skin- binding peptide with an organic sunscreen agent, are described. The skin- binding peptide part of the peptide-based organic sunscreen binds strongly to the skin, thus keeping the organic sunscreen agent attached to the skin for long lasting protection. Sunscreen compositions comprising the peptide-based organic sunscreens are also provided.
摘要翻译：描述了通过将皮肤结合肽与有机防晒剂偶联形成的基于肽的有机防晒剂。基于肽的有机防晒剂的皮肤结合肽部分与皮肤强烈结合，因此保持有机防晒剂附着于皮肤以获得持久保护。还提供了包含基于肽的有机防晒剂的防晒组合物。

10. 发明申请

WO2008105948A3 ROBOTIC VEHICLE WITH TRACKS AND FLIPPERS 审中-公开
标题翻译：机动车用履带和拖鞋
公开(公告)号：WO2008105948A3
公开(公告)日：2009-08-06
申请号：PCT/US2007080138
申请日：2007-10-02
申请人： IROBOT CORP , COUTURE ADAM P , PAGE RICHARD , O'BRIEN JOHN P , FILIPPOV MIKHAIL , SHEIN ANDREW
发明人： COUTURE ADAM P , PAGE RICHARD , O'BRIEN JOHN P , FILIPPOV MIKHAIL , SHEIN ANDREW
IPC分类号： B25J5/00 , B62D55/075 , B62D57/024
CPC分类号： B62D55/075 , B25J5/005 , B25J11/0025 , B62D55/065 , B62D57/024 , Y10S901/01
摘要： A robotic vehicle (10,100,150A,150B150C,160,1000,1000A,1000B,1000C) includes a chassis (20,106,152,162) having front and rear ends (20A,152A,20B,152B) and supported on right and left driven tracks (34,44,108,165). Right and left elongated flippers (50,60,102,154,164) are disposed on corresponding sides of the chassis and operable to pivot. A linkage (70,156,166) connects a payload deck assembly (D1,D2,D3,80,158,168,806), configured to support a removable functional payload, to the chassis. The linkage has a first end (70A) rotatably connected to the chassis at a first pivot (71), and a second end (70B) rotatably connected to the deck at a second pivot (73). Both of the first and second pivots include independently controllable pivot drivers (72,74) operable to rotatably position their corresponding pivots (71,73) to control both fore-aft position and pitch orientation of the payload deck (D1,D2,D3,80,158,168,806) with respect to the chassis (20,106,152,162).
摘要翻译：机器人车辆（10,100,150A，150B150C，160,1000,1000A，1000B，1000C）包括具有前端和后端（20A，152A，20B，152B）并支撑在左右驱动轨道（34）上的底盘（20,106,152,162） 44108165）。右和左细长鳍状物（50,60,102,154,164）设置在底盘的相应侧上并且可操作以枢转。连杆（70,156,166）将配置成支撑可移动功能有效载荷的有效载荷甲板组件（D1，D2，D3,80,158,168,806）连接到底盘。连杆具有在第一枢轴（71）处可转动地连接到底架的第一端（70A）和在第二枢轴（73）处可旋转地连接到甲板的第二端（70B）。第一和第二枢轴都包括可独立控制的枢转驱动器（72,74），其可操作以可旋转地定位其对应的枢轴（71,73），以控制有效载荷甲板（D1，D2，D3，D3）的前后位置和俯仰方向， 80,158,168,806）相对于底盘（20,106,152,162）。

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