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    • 2. 发明申请
    • ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS
    • 用于控制反相胶束的ISOXAZOLINES
    • WO2007070606A3
    • 2007-08-02
    • PCT/US2006047628
    • 2006-12-13
    • DU PONTPATEL KANU MAGANBHAI
    • PATEL KANU MAGANBHAI
    • A01N43/80C07D413/04C07D413/14
    • C07D413/04A01N43/80C07D413/14
    • Disclosed are compounds of Formula (1), including all geometric and stereoisomers, N-oxides and salts thereof, wherein A is selected from the group consisting of CR 3 and N; each R 3 is independently H, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfÊnyl, C 1 -C 6 haloalkylsulfÊnyl, C 1 -C 6 alkylsulfonyl C 1 -C 6 haloalkylsulfonyl, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, -CN, -NO 2 or -CR 9 =NOR 10 ; or a phenyl or a pyridinyl ring, each ring optionally substituted with one to three substituents independently selected from R 8 ; Q is a 5- or 6-membered saturated or unsaturated heterocyclic ring optionally substituted with one or more substituents independently selected from halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -CN, -NO 2 , -N(R 11 )R 12 . -C(W)N(R 13 )RH 14 , -C(O)OR 15 and R 16 ; or Q is -CO=W)NR 4 R 5 ; and R 1 , R 2 , R 4 . R 5 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 ; R l4 , R 15 , R 16 , W and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods f controlling an invertebrate pest comprising contacting the invertebrate pest or i environment with a biologically effective amount of a compound or a composition of the invention.
    • 公开了式(1)的化合物,其包括所有几何和立体异构体的N-氧化物及其盐,其中A选自CR 3和N; 每个R 3独立地为H,卤素,C 1 -C 6烷基,C 1 -C 6亚烷基,C 1 -C 6 卤代烷基,C 3 -C 6环烷基,C 3 -C 6卤代环烷基,C 3 -C 6环烷基,C 3 -C 6环烷基, C 1 -C 6烷氧基,C 1 -C 6卤代烷氧基,C 1〜 C 1 -C 6烷硫基,C 1 -C 6卤代烷硫基,C 1 -C 6烷基, C 1 -C 6烷基亚磺酰基,C 1 -C 6卤代烷基亚磺酰基,C 1 -C 6烷基磺酰基C 1 -C 6烷基磺酰基, C 1 -C 6烷基磺酰基,C 1 -C 6烷基氨基,C 2 -C 3烷基氨基,C 1 -C 6烷基氨基,C 1 -C 6烷基氨基, -N 2 - , - N 2 - , - N 2 - , - N 2 - , - N 2 - 或苯基或吡啶环,每个环任选被一至三个独立地选自R 8的取代基取代; Q是任选被一个或多个独立地选自卤素,C 1 -C 6烷基,C 1 -C 6烷基的取代基取代的5或6元饱和或不饱和杂环 C 1 -C 6卤代烷基,C 3 -C 6 -C 6环烷基,C 3 -C 卤代环烷基,C 1 -C 6烷氧基,C 1 -C 6烷基,C 1 -C 6烷基,C 1 -C 6 - 卤代烷氧基,C 1 -C 6烷硫基,C 1 -C 6卤代烷硫基,C 1 -C 6烷基, C 1 -C 6烷基亚磺酰基,C 1 -C 6卤代烷基亚磺酰基,C 1 -C 3烷基亚磺酰基,C 1 -C 6烷基亚磺酰基, C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基,-CN,-NO 2,-N(R 11) )R 12 。 -C(W)N(R 13)RH 14,-C(O)OR 15和R 16 >; 或Q是-CO = W)NR 4 R 5; 和R 1,R 2,R 4,和R 4。 R 5,R 8,R 9,R 10,R 11, R 12,R 13; R 14,R 15,R 16,W和n如本公开所定义。 还公开了含有式1化合物的组合物和控制无脊椎动物害虫的方法f,包括使无脊椎害虫或环境与生物有效量的本发明化合物或组合物接触。
    • 5. 发明申请
    • 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS
    • 用于控制反相胶束的5-ARYL ISOXAZOLINES
    • WO2007075459A3
    • 2008-01-31
    • PCT/US2006047999
    • 2006-12-15
    • DU PONTLAHM GEORGE PHILIPPATEL KANU MAGANBHAIPAHUTSKI THOMAS FRANCIS JRSMITH BENJAMIN KENNETHLONG JEFFREY KEITH
    • LAHM GEORGE PHILIPPATEL KANU MAGANBHAIPAHUTSKI THOMAS FRANCIS JRSMITH BENJAMIN KENNETHLONG JEFFREY KEITH
    • C07D413/10A01N43/80A61K31/42
    • C07D413/14A01N43/80C07D261/04C07D413/04C07D413/10C07D413/12C07D417/10C07D417/14
    • Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A 1 , A 2 and A 3 are independently selected from the group consisting of CR 3 and N; B 1 B 2 and B 3 are independently selected from the group consisting of CR 2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -CN, -NO 2 , -N(R 4 )R 5 , -C(W)N(R4)R 5 , -C(O)OR 5 and R 8 ; or -S(O) 2 N(R 2I )R 22 , -S(O) p R 25 or -S(O)(=NR 28 )R 29 ; and R l , R 2 , R 3 , R 4 , R 5 , R 8 , R 21 , R 22 , R 25 , R 28 , R 29 ; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition' of the invention.
    • 公开了式1的化合物,包括所有几何和立体异构体,N-氧化物及其盐,其中A 1,A 2和A 3 >独立地选自CR 3和N; B 1,B 2,B 3和B 3独立地选自CR 2和N; Q是苯环或5或6元饱和或不饱和杂环,每个环任选地被一个或多个独立地选自卤素,C 1 -C 6 - C 1 -C 6烷基,C 1 -C 6卤代烷基,C 3 -C 6环烷基,C 1 -C 6烷基, C 3 -C 6卤代环烷基,C 1 -C 6烷氧基,C 1 -C 6烷基,C 1 -C 6烷基, C 1 -C 6卤代烷氧基,C 1 -C 6烷硫基,C 1 -C 6卤代烷硫基 C 1 -C 6烷基亚磺酰基,C 1 -C 6卤代烷基亚磺酰基,C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基亚磺酰基, C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基,-CN,-NO 2 - , - N(R 4)R 5,-C(W)N(R 4)R 5,-C(O)OR 5< 8>; 或-S(O)2 N(R 2 2)R 22,-S(O)p R 或-S(O)(= NR 28)R 29; 和R 1,R 2,R 3,R 4,R 5, R 8,R 21,R 22,R 25,R 28, R 29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物,其包括使无脊椎害虫或其环境与生物有效量的本发明的化合物或组合物接触。