专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012076124A3 ANTIBACTERIAL COATING FOR AN IMPLANT AND METHOD FOR PRODUCING SAID COATING 审中-公开
标题翻译：抗菌涂料用于生产这种涂层的植入体和方法
公开(公告)号：WO2012076124A3
公开(公告)日：2012-09-27
申请号：PCT/EP2011005963
申请日：2011-11-28
申请人： DOT GMBH , NEUMANN HANS-GEORG , PRINZ CORNELIA , LEMBKE ULRICH
发明人： NEUMANN HANS-GEORG , PRINZ CORNELIA , LEMBKE ULRICH
IPC分类号： A61L27/30 , A61L27/54
CPC分类号： A61L27/306 , A61L27/06 , A61L27/54 , A61L2300/102 , A61L2300/404 , A61L2300/608 , C09D5/14 , Y10T428/12785 , Y10T428/265 , Y10T428/31678
摘要： The invention relates to the antibacterial coating for an implant, which is characterized in that the coating contains copper. The invention also relates to a method for producing an antibacterial coating for an implant, wherein the coating is applied by means of a PVD process, said method being characterized in that the layer produced contains a proportion of copper.
摘要翻译：本发明涉及抗菌涂层的植入物，其特征在于，所述涂层包含铜。本发明还涉及一种用于制造上的抗菌涂层用于植入物，其中所述涂层通过PVD工艺来施加并且其特征在于，所产生的层中含有的铜含量

2. 发明申请

WO2007082810A3 MODULAR REVISION SOCKET FOR HIP-JOINT PROSTHESIS AND ANCHORING PIN THEREFOR 审中-公开
标题翻译：模块化修订泛为髋关节置换术与锚杆锥THEREFOR
公开(公告)号：WO2007082810A3
公开(公告)日：2008-02-21
申请号：PCT/EP2007050145
申请日：2007-01-08
申请人： DOT GMBH , NEUMANN HANS-GEORG , KLINKENBERG ERNST-DIETER
发明人： NEUMANN HANS-GEORG , KLINKENBERG ERNST-DIETER
IPC分类号： A61F2/34 , A61B17/68 , A61F2/30
CPC分类号： A61F2/30721 , A61B17/68 , A61B17/8038 , A61B17/86 , A61F2/30749 , A61F2/30767 , A61F2/34 , A61F2/4609 , A61F2002/30326 , A61F2002/30367 , A61F2002/30378 , A61F2002/30403 , A61F2002/30433 , A61F2002/30484 , A61F2002/30538 , A61F2002/30578 , A61F2002/30604 , A61F2002/30616 , A61F2002/3069 , A61F2002/30785 , A61F2002/30787 , A61F2002/30794 , A61F2002/30906 , A61F2002/3401 , A61F2002/3404 , A61F2002/3454 , A61F2002/3458 , A61F2002/3491 , A61F2002/4629 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2250/0006 , A61F2250/0037 , A61F2310/00023 , A61F2310/00407 , A61F2310/00796
摘要： The invention relates to a modular revision socket for hip-joint prosthesis, which can be adapted during revision surgery to the defects found intraoperatively in the acetabulum. The modular revision socket according to the invention consists of a socket base (1), a fixing plate (3), one or more anchoring pins (2) and an inlay. The socket base (1) is an oval press-fit shell comprising two polyaxial expansion press-fit bearings (6) for the anchoring pins (2), a mounting bearing (13) for the fixing plate (3) and a recess (12) for expanding the range of movement and preventing an impingement. The fixing plate (3) is fixed to the socket base (1) to form a block. The positive fit assembly allows pitching moments in the mounting bearing (13) to be absorbed, thus ensuring a high degree of stability in the implant. The anchoring pins (2) comprise several functional regions. A tip region (17) acts as a guide when the prosthesis is pressed in, a guide region (18) acts as a rotational lock and compresses the spongiose bone when the prosthesis is pressed in, a retaining region (19) ensures mechanical stability in the bone and a head region (20) fixes the prosthesis in the revision socket and allows said prosthesis to be locked in its polyaxial alignment.
摘要翻译：本发明涉及一种模块化髋关节修正关节成形术泛为其可以根据在翻修手术过程中髋臼缺损术中遇到被适配。根据本发明的模块化杯修订包括一个插座基体（1），一个紧固带（3），一个或若干个锚定销（2）和插座插入件。泛基体（1）被成形为卵形Pressfitschale并且具有两个多轴Spreizpressfitlager（6）用于锚定销（2），用于定影标签（3）和用于扩展移动和防止冲击的范围内的凹部（12）的安装轴承（13）。紧固片（3）是在块安装在秤盘上基体（1）。由于它们的形状配合的安装倾斜力矩在安装轴承（13）被接收，并确保植入物的高稳定性。锚固销（2）具有多个功能区。的前端部（17）用于在驱动期间引导，引导部（18），用于防止插入期间扭曲和松质骨的压缩，保持部（19）确保了在骨的机械稳定性和头部部分（20）用于固定在修订杯并可实现锁定多轴方向。

3. 发明申请

WO2005087284A3 COMPOSITE MATERIALS BASED ON POLYSILICIC ACID AND METHOD FOR THE PRODUCTION THEREOF 审中-公开
标题翻译： COMPOSITE基于聚硅酸和聚合物
公开(公告)号：WO2005087284A3
公开(公告)日：2006-05-11
申请号：PCT/EP2005051012
申请日：2005-03-07
申请人： DOT GMBH , TELLER MARIANNE , NEUMANN HANS-GEORG
发明人： TELLER MARIANNE , NEUMANN HANS-GEORG
IPC分类号： A61L27/30 , A61L27/32 , A61L27/44 , A61L27/46 , A61L27/56
CPC分类号： A61L27/306 , A61L27/32 , A61L27/446 , A61L27/46 , A61L27/56 , A61L2420/04 , A61L2430/02
摘要： The invention relates to composite materials based on polysilicic acid, said materials containing novel compositions which have improved material properties and can be in the form of dispersions, pastes, powders, granulated materials, layers or compact moulded bodies. The aim of the invention is to produce composite materials based on polysilicic acid with improved mechanical properties. To this end, the composite materials contain polysilicic acid, between 0.01 and 20 mass % of an organic polymer, more than 15 mass % of at least one calcium phosphate phase, and optionally a use-specific additive. The material produced according to the invention can be implanted or injected. The composition of the composite material with the resulting properties enables the composite material to be used for bone substitution and/or bone regeneration in both human medicine and animal medicine. The inventive material can also be used to heal wounds.
摘要翻译：本发明涉及一种基于聚硅酸的复合材料，其具有具有改进的新的组合物的材料特性，并且可以是在分散体，糊，粉末，颗粒，压缩层或模制品的形式。基于聚硅酸生产复合材料的这一任务具有改进的机械性能得以实现是因为该复合材料的聚硅酸，在0.01〜20质量％的比例的有机聚合物，至少一种Calciumphosphalphase超过15个质量中所占的比例％，并且任选地包含一个应用程序特定的添加剂。根据本发明制得的材料是可植入的或injezierbar。用所得性质的复合材料的组合物，使得有可能使用用于骨置换的复合材料和/或用于在人类和兽医应用的骨再生。此外，该材料可用于伤口愈合的目的。

4. 发明申请

WO2010072606A4 MODULAR HIP JOINT ENDOPROSTHESIS 审中-公开
标题翻译：模块化髋关节
公开(公告)号：WO2010072606A4
公开(公告)日：2010-08-12
申请号：PCT/EP2009067057
申请日：2009-12-14
申请人： DOT GMBH , KLINKENBERG ERNST-DIETER , NEUMANN HANS-GEORG
发明人： KLINKENBERG ERNST-DIETER , NEUMANN HANS-GEORG
IPC分类号： A61F2/34 , A61F2/00 , A61F2/30
CPC分类号： A61F2/34 , A61F2002/305 , A61F2002/30604 , A61F2002/3064 , A61F2002/3448 , A61F2220/0025
摘要： The invention relates to a modular hip joint endoprosthesis having a rolling-friction-supported prosthesis head. The aim of the invention is to develop a modular hip joint endoprosthesis that has a significantly reduced frictional resistance between the implant socket sliding surface and the joint ball and that allows a nearly natural range of movement. According to the invention, the aim is achieved by inserting sliding bodies (running balls) in order to transmit the movement between the articulation surfaces of the joint ball and of the socket, wherein said sliding bodies in addition to reducing the friction also cause an effective enlargement of the joint ball diameter and thus permit a greater range of movement. The sliding-body cage is designed in such a way that collisions with the implant stem under load conditions that occur periodically do not impair the function of the joint.
摘要翻译：本发明涉及一种具有假体头rollreibungsgelagertem模块化髋关节内假体。本发明的目的是开发与Implantatpfannengleitfläche和球窝接头，其允许运动的接近自然的范围之间显著降低摩擦阻力模块化髋关节。根据本发明，该目的是通过引入滑块（运行球）用于切换所述接合球窝的关节表面，导致除了摩擦的减少和关节球直径的有效放大，并且因此允许运动的更大的范围之间的运动来实现的。滑动体被设计成使得与周期性地发生的负载条件下的植入物柄碰撞，关节的功能不干扰。

5. 发明申请

WO2007082807A3 POLYAXIALLY ALIGNABLE STABILISING ELEMENT FOR ENDOPROSTHESES 审中-公开
标题翻译：多轴定向的稳定元件FOR用假体
公开(公告)号：WO2007082807A3
公开(公告)日：2007-10-18
申请号：PCT/EP2007050140
申请日：2007-01-08
申请人： DOT GMBH , NEUMANN HANS-GEORG , KLINKENBERG ERNST-DIETER
发明人： NEUMANN HANS-GEORG , KLINKENBERG ERNST-DIETER
IPC分类号： A61F2/30
CPC分类号： A61F2/30721 , A61B17/68 , A61B17/8038 , A61F2/30749 , A61F2/30767 , A61F2002/30154 , A61F2002/30171 , A61F2002/3028 , A61F2002/30332 , A61F2002/30367 , A61F2002/30378 , A61F2002/30403 , A61F2002/30484 , A61F2002/30507 , A61F2002/30538 , A61F2002/3069 , A61F2002/30797 , A61F2002/3401 , A61F2220/0025 , A61F2220/0033 , A61F2230/0021 , A61F2230/005 , A61F2230/0063 , A61F2250/0006 , A61F2310/00023 , A61F2310/00407 , A61F2310/00796
摘要： The invention relates to a polyaxially alignable stabilising element for endoprostheses. The aim of the invention is to develop a stabilising element, which preferably can be assembled after the optimal positioning of the implant and is distinguished by an adapted form and functional regions. The element is characterised by the following: a semi-spherical guide tip (1a) is designed to guide the stabilising pin (1), whilst the latter is pressed into prepared under-dimensioned bores in the bones; a guide region, which adjoins the guide tip (1a), consists of conical, polyhedral propelling surfaces (1b) that are designed to act as rotational locks and compress the spongiose bone as the element is pressed in; an osteointegrative region that adjoins the guide region, has a functionally modified surface and secures the mechanical stability of the stabilising pin (1) once the bones have fused; an expansion region (1e) that terminates the element and is configured to resemble a plug with spherical sub-surfaces for fixing the stabilising pin (1) in the implant; and a region with a spherical surface (1f) in the expansion region of the stabilising pin (1) allows the polyaxial alignment of the latter (1).
摘要翻译：本发明描述了一种用于内置假体稳定化元素的多轴可调性。任务是开发一种稳定元件，其优选地安装到所述植入物和其特征在于一个适于形状及功能区域的最佳定位。它的特征在于，半球形导端（1a）中的压入在骨中制备的矮小孔期间稳定销（1）的引导被使用时，引导部，其引导末端（1a）的从驱动面（1b）中，邻接该锥形是由多面体，并用于防止在压制过程中的松质骨的扭曲和压缩，其具有经官能改性的表面，并通过粘附在骨中的稳定销（1）的机械稳定性的后续osteointegrativer区域确保了最终的膨胀区域（1e）的这与球形部分表面类似地构造销钉，用于稳定销的固定（1）的在植入物和稳定销（1）的方法通过在所述销（1）的膨胀区（1e）的球形表面（1F）的区域的多轴位置成为可能使用。

6. 发明申请

WO03052164A2 METHOD FOR COATING A SUBSTRATE WITH CALCIUM PHOSPHATE 审中-公开
标题翻译：法涂层与钙磷酸盐衬底
公开(公告)号：WO03052164A2
公开(公告)日：2003-06-26
申请号：PCT/EP0213819
申请日：2002-12-06
申请人： DOT GMBH , BECKER PETRA , BUHRMEISTER MISCHA , NEUMANN HANS-GEORG , TELLER MARIANNE
发明人： BECKER PETRA , BUHRMEISTER MISCHA , NEUMANN HANS-GEORG , TELLER MARIANNE
IPC分类号： A61L27/00 , A61F2/00 , A61F2/28 , A61F2/30 , A61L24/02 , A61L27/32 , C23C18/00 , C23C20/08 , C23C24/08 , C23C30/00
CPC分类号： A61L24/02 , A61F2/28 , A61F2/30767 , A61F2310/00023 , A61F2310/00796 , A61F2310/0097 , A61F2310/00976 , A61L27/32 , A61L2430/02 , C23C18/00 , C23C24/08 , C23C30/00
摘要： The invention relates to a novel method for coating substrates with calcium phosphate. Prior art methods do not permit temperature-sensitive substrates or particles to be coated with calcium phosphates or it requires several method steps for carrying out this coating. The aim of the novel method is to be able to carry out a simple coating for all materials as well as for particles. To this end, the invention provides that the substrate to be coated is placed in a calcium phosphate gel, whereupon this substrate that is coated with the gel is dried. Afterwards, the calcium phosphate particles not adhering to the substrate are removed. According to the invention, the substrate can also be placed inside a colloidal solution of SiO2 containing a calcium phosphate, whereupon the mixture is constantly set in motion, the solvent is removed, and the substrate is provided with a calcium phosphate layer by condensing the colloidal SiO2 on the surface of the substrate. The coated substrates can, particularly when it concerns coated particles, be used as bone substitute material.
摘要翻译：本发明涉及一种用磷酸钙涂覆基材的新方法。与已知方法，它是不可能涂覆温度敏感的基材或与钙磷酸盐或用于涂覆多个工艺步骤的颗粒，它是必需的。随着新的方法，对所有材料以及用于颗粒的简单的涂布是可行的。根据本发明，用于涂层中的基板被带入磷酸钙凝胶，和干燥与凝胶涂覆的基底。随后，将非粘附到磷酸盐底钙颗粒被去除。根据本发明，可以被引入到在SiO 2的含磷酸盐的钙胶体溶液，然后将混合物不停地移动，除去溶剂的衬底和衬底由胶体二氧化硅的缩合设置有磷酸钙层的基板的表面上。经涂覆的基材可以，尤其是当它被涂覆的颗粒，被用作骨替代材料。

7. 发明申请

WO2010142621A1 STABILIZING ELEMENT FOR HIP JOINT PROSTHETICS 审中-公开
标题翻译：稳定装置髋关节置换术
公开(公告)号：WO2010142621A1
公开(公告)日：2010-12-16
申请号：PCT/EP2010057874
申请日：2010-06-07
申请人： DOT GMBH , KLINKENBERG ERNST-DIETER , NEUMANN HANS-GEORG
发明人： KLINKENBERG ERNST-DIETER , NEUMANN HANS-GEORG
IPC分类号： A61F2/34 , A61B17/68
CPC分类号： A61F2/34 , A61F2/30721 , A61F2/30734 , A61F2/30749 , A61F2002/30387 , A61F2002/30507 , A61F2002/30578 , A61F2002/3069 , A61F2002/30787 , A61F2002/3093 , A61F2002/3401 , A61F2002/3404 , A61F2002/3454 , A61F2220/0025
摘要： The invention relates to a stabilizing element for the socket of a hip joint prosthesis that can improve the primary stable seat of the socket in the implant bed. The problem of the invention is to develop a stabilizing element for a modular oval revision socket in such a way that the stabilizing element can be set intraoperatively when the revision socket is already pressed into the implant bed depending on the defect situation. According to the invention, the mounting link (3) is inserted into a link bearing (13) of the socket base body (1), which link bearing has a dovetail-shaped groove (15). The end face (15a) of the link is wedge-shaped in the mounting area, and wedge-shaped studs (15b) are arranged on both side faces at a distance from the end face of the link. The wedge-shaped studs are dimensioned so that a short insertion path into the bearing is enabled and the wedge-shaped studs do not protrude from the bearing after mounting.
摘要翻译：本发明涉及一种用于能够提高座椅底板在植入位点的初级稳定性的髋关节的插座中的稳定元件。本发明的目的是开发，使得它可以在术中在卷曲植入修订杯响应于所述缺陷的情况放置用于模块化卵形修订杯稳定元件。根据本发明，在具有燕尾形槽（15）的插座基体（1）的拉片备料（13），引入的紧固片（3）。的标签的端面（15A）形成在固定区域楔形并在两侧面楔形销（15B）被布置成它们从突片的端面间隔开。它们尺寸，使得一个简短的介绍路径在营地成为可能，他们不从安装后的营地突出。

8. 发明申请

WO2007090880A3 REABSORABABLE CALCIUM PHOSPHATE BASED BIOPOLYMER-CROSS-LINKED BONE REPLACEMENT MATERIAL 审中-公开
标题翻译：吸收钙磷酸盐基BIOPOLYMERVERNETZTES骨替代材料
公开(公告)号：WO2007090880A3
公开(公告)日：2008-06-26
申请号：PCT/EP2007051251
申请日：2007-02-09
申请人： DOT GMBH , NEUMANN HANS-GEORG , KLINKENBERG ERNST-DIETER , SCHAUER FRIEDER , LINDEQUIST ULRIKE , JUELICH WOLF-DIETER , MIKOLASCH ANNETT , MANDA KATRIN
发明人： NEUMANN HANS-GEORG , KLINKENBERG ERNST-DIETER , SCHAUER FRIEDER , LINDEQUIST ULRIKE , JUELICH WOLF-DIETER , MIKOLASCH ANNETT , MANDA KATRIN
IPC分类号： A61L24/02 , A61L24/04 , A61L27/44
CPC分类号： C09J175/04 , A61L24/043 , C08G18/10 , C08G18/428 , C08G18/6446 , C08L89/00 , C09J189/00 , Y10T428/2982 , C08L67/04 , C08G18/64
摘要： The invention relates to a reabsorbable bone replacement material made of calcium phosphate particles of different phases which are embedded in an inventive-specific cross-linked collagen matrix. The aim of the invention is to form a non-brittle, bone replacement moulded body having a positive fit, i.e. having a shape which is anatomic and/or correspondes to the defect, which perfectly fills the bone defect and can be reabsorbed thereby. Said aim is achieved by producing the bone replacement material made of a mixture of calcium phosphate particles which is embedded in an inventive cross-linked collagen matrix. In particular, the collagen cross-linking is achieved by a Laccase-induced peptide cross-linking and suitable bridge molecules. Essentially substituted dihydroxyarmotes and/or substrates of the lignolytic polyphenoloxidases, such as Laccases, are suitable as bridge molecules. Also, monocyclic ortho-dihydroxyaromates, monocyclic para-dihydroxyaromates, bicyclic monohydroxyaromates, polycyclisc monohydroxyaromates, bicyclic dihydroxyaromates, polycyclic dihydroxyaromates, bicyclic trihydroxyaromates, polycyclic trihydroxyaromates, or mixtures thereof are used. The inventive hydroxyaromates are not part of a polymer chain as opposed to the known conchal adhesive.
摘要翻译：本发明涉及包含不同相的磷酸钙颗粒，其特定于嵌入在交联的胶原基质的本发明可再吸收的骨替代材料。本发明的任务是提供一种正的，即产生解剖学上或完全填充骨缺损，也是可再吸收的缺陷相应形状的非脆性骨替代形主体。对象的溶液通过生产从Calciumphoshatpartikeln的混合物骨替代材料的嵌入在根据本发明的交联的胶原蛋白基质来实现。特别地，所述胶原交联是由漆酶诱导的交联和肽合适的桥接分子来实现的。由于桥接分子基本上取代dihydroxyaromates和/或木质素降解多酚氧化酶的底物如漆酶是。因此单环的邻二羟基芳族化合物，单环对位二羟基的，双环monohydroxyaromates多环monohydroxyaromates双环芳族二羟基化合物，多环芳族二羟基化合物，三羟基双环，多环trihydroxyaromates，或它们的混合物。羟基芳发明不在与已知的贻贝的粘合剂的聚合物链的一部分。

9. 发明申请

WO0205862A8 BIOACTIVE CALCIUM PHOSPHATE COMPOSITE LAYERS ELECTROCHEMICALLY DEPOSITED ON IMPLANTS 审中-公开
标题翻译：电镀，生物活性磷酸钙复合层植入物上
公开(公告)号：WO0205862A8
公开(公告)日：2002-05-30
申请号：PCT/EP0006838
申请日：2000-07-17
申请人： DOT GMBH , NEUMANN HANS GEORG , ZEGGEL PETER , BECKER PETRA
发明人： NEUMANN HANS-GEORG , ZEGGEL PETER , BECKER PETRA
IPC分类号： A61L27/00 , A61F2/28 , A61L20060101 , A61L27/32
CPC分类号： A61F2/30767 , A61F2002/3092 , A61F2310/00796 , A61L27/32 , A61L27/56 , A61L2430/02
摘要： The invention relates to calcium phosphate composite layers which are electrochemically deposited on bone implants. Implants which are coated in such a way are implanted without cement and are characterised by improved growing-in behaviour. Said highly porous composite layers on implants are made of at least two calcium phosphate phases of different solubility. The highly porous structure of said layers facilitates the immobilisation of cells from which new bone tissue can be made. The different solubility of the individual layer components ensures local concentration of calcium and phosphate ions which accelerates the incorporation process and which adapts to said process over the course of time.
摘要翻译：本发明涉及一种电化学沉积在骨植入物的磷酸钙复合层。这种涂层的植入物被植入无水泥和通过改进的向内生长的特征。上植入物宣布Erfinding高度多孔性复合体层由不同溶解度的两种或更多种磷酸钙相的。这些层的高度多孔的结构有利于细胞，其中之一，起始形式新的骨组织的固定。各个层组分的不同溶解度保证了愈合过程加速并超过钙和磷酸根离子的时间局部浓度适于这一过程。

10. 发明申请

WO9714964A2 PATIENT-SPECIFIC IMMUNOADSORBENTS FOR EXTRACORPORAL APHERESIS AND METHODS OF PRODUCING SAID IMMUNO-ADSORBERS 审中-公开
标题翻译：用于体外单采和方法患者特异性的immunoadsorber生产同样
公开(公告)号：WO9714964A2
公开(公告)日：1997-04-24
申请号：PCT/DE9601910
申请日：1996-10-03
申请人： PRIVATES INST BIOSERV GMBH , HEINRICH HANS WERNER , RAMLOW WOLFGANG , BOEDEN HANS FRIEDRICH , NEUMANN HANS GEORG , MEYER UDO AQUACONSULT GMBH , TELLER JOACHIM
发明人： HEINRICH HANS-WERNER , RAMLOW WOLFGANG , BOEDEN HANS-FRIEDRICH , NEUMANN HANS-GEORG , MEYER UDO , TELLER JOACHIM
IPC分类号： G01N33/564 , A61K35/14 , A61K39/00 , A61K39/395 , A61M1/34 , A61M1/36 , A61P37/06 , B01J20/22 , B01J20/26 , G01N33/569 , G01N33/543 , G01N33/548
CPC分类号： A61M1/3679 , A61M1/3486 , B01J20/3212 , B01J20/3274 , B01J2220/4856 , C07K17/02 , Y10S436/824 , Y10S530/868
摘要： The invention relates to the production of multiple-application patient-specific immunoadsorbents which can be used for extracorporal apheresis in patients suffering from disorders caused by dysregulation of the immune system. Conventional methods are used to isolate the immune complexes from the patient's blood and appropriate methods are applied to separate the immune complexes into antigens and antibodies. The antigens and antibodies thus reactivated are coupled individually or as a mixture covalently to suitable carriers which are used as immunoadsorbents for the patient from whom the immune complexes originate. This facilitates production of specific immunoadsorbents even for patients suffering from rare auto-immune diseases.
摘要翻译：本发明涉及制备适用通用的，特定于患者的免疫吸附器，其可以在从该被免疫系统失调引起的疾病的患者使用用于体外血液分离到。通过常规方法来分离从患者的血液，其通过适当的方法抗原和抗体分离的免疫复合物。这样再活化抗原和抗体可以单独或作为混合物耦合共价合适的载体，其用作免疫用于从谁免疫复合物衍生的患者。因此特异性作用immunoadsorber也可以为从罕见的自身免疫性疾病的患者进行。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式