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1. 发明申请

WO2009085743A1 ENZYMATIC PREVENTION AND CONTROL OF BIOFILM 审中-公开
标题翻译：生物技术的预防和控制
公开(公告)号：WO2009085743A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/086959
申请日：2008-12-16
申请人： DANISCO US INC., GENENCOR DIVISION , BARNETT, Christopher , KUMAR, Manoj , WHITED, Gregory M.
发明人： BARNETT, Christopher , KUMAR, Manoj , WHITED, Gregory M.
IPC分类号： C11D3/386
CPC分类号： A01N63/02 , C11D3/386 , C11D3/38636
摘要： The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.
摘要翻译：本发明提供从表面去除生物膜的方法，组合物和试剂盒。本文描述的方法包括同时或顺序地将表面上的生物膜同时或顺序施用过水解酶和其它酶（例如蛋白酶，葡聚糖酶，酯酶，甘露聚糖酶，磷脂酶，纤维素酶和/或淀粉酶）的混合物，以去除生物膜。

2. 发明申请

WO2008088472A2 MILK PROTEIN HYDROLYZATES WITH REDUCED IMMUNOGENIC POTENTIAL 审中-公开
标题翻译：乳蛋白水解产物具有降低的免疫原性潜力
公开(公告)号：WO2008088472A2
公开(公告)日：2008-07-24
申请号：PCT/US2007/024723
申请日：2007-12-03
申请人： DANISCO US, INC., GENENCOR DIVISION , KUMAR, Manoj , WONG, David
发明人： KUMAR, Manoj , WONG, David
IPC分类号： A23J3/34 , A23L1/305 , A23C9/12 , A23C21/02
CPC分类号： A23J3/343 , A23C9/1209 , A23C21/02 , A23L33/18 , A61K8/64 , A61Q19/02 , C12Y304/21019
摘要： Hydrolyzate compositions comprising at least one milk protein or whey hydrolyzed with at least one proteolytic enzyme are provided. The hydrolyzates reduce the immunogenicity of the milk or whey protein in a subject predisposed to having an immune reaction to the protein. Methods for making the compositions are also provided, as food products and nonfood products comprising the compositions.
摘要翻译：提供了包含至少一种乳蛋白或用至少一种蛋白水解酶水解的乳清的水解产物组合物。水解产物降低易于对蛋白质产生免疫反应的受试者中的乳或乳清蛋白的免疫原性。还提供了制备组合物的方法，作为食品和包含该组合物的非食品产品。

3. 发明申请

WO2008005571A2 DETERGENTS WITH STABILIZED ENZYME SYSTEMS 审中-公开
标题翻译：具有稳定酶系统的洗涤剂
公开(公告)号：WO2008005571A2
公开(公告)日：2008-01-10
申请号：PCT/US2007/015672
申请日：2007-07-06
申请人： DANISCO US, INC., GENENCOR DIVISION , KUMAR, Manoj , POULOSE, Ayrookaran J.
发明人： KUMAR, Manoj , POULOSE, Ayrookaran J.
IPC分类号： C11D3/386 , C11D3/39
CPC分类号： C11D3/38663 , C11D3/046 , C11D3/122 , C11D3/30 , C11D3/3463
摘要： The present invention provides methods and compositions for the stabilization of oxidase enzymes during storage. In some preferred embodiments, the oxidase is a component of liquid detergent compositions. In some particularly preferred embodiments, the oxidase is stabilized by the addition of a reversible inhibitor of the oxidase to a liquid detergent. In some particularly preferred embodiments, the oxidase is stabilized with bisulfite. In further preferred embodiments, the use of a reversible inhibitor also prevents premature generation of peroxide during storage of liquid detergent. In additional embodiments, liquid detergent formulations comprised of oxidase enzyme, its substrate, and its reversible inhibitor produce active oxygen species (peroxide) upon dilution of the liquid detergent in laundry wash liquor.
摘要翻译：本发明提供了用于在储存期间稳定氧化酶的方法和组合物。在一些优选的实施方案中，氧化酶是液体洗涤剂组合物的组分。在一些特别优选的实施方案中，通过将氧化酶的可逆抑制剂加入到液体洗涤剂中来稳定氧化酶。在一些特别优选的实施方案中，氧化酶用亚硫酸氢盐稳定。在进一步优选的实施方案中，使用可逆抑制剂还防止在液体洗涤剂储存过程中过早产生过氧化氢。在另外的实施方案中，由氧化酶，其底物和其可逆抑制剂组成的液体洗涤剂制剂在洗涤液洗涤液中稀释液体洗涤剂时产生活性氧物质（过氧化物）。

4. 发明申请

WO2008021050A1 NATIVE GRAIN AMYLASES IN ENZYME COMBINATIONS FOR GRANULAR STARCH HYDROLYSIS 审中-公开
标题翻译：颗粒淀粉水解酶组合中的原料颗粒
公开(公告)号：WO2008021050A1
公开(公告)日：2008-02-21
申请号：PCT/US2007/017485
申请日：2007-08-03
申请人： DANISCO US, INC., GENENCOR DIVISION , KUMAR, Manoj
发明人： KUMAR, Manoj
IPC分类号： C12P7/06 , C12P19/14
CPC分类号： C12P7/06 , C12P19/14 , Y02E50/17
摘要： Described herein are starch hydrolysis processes for obtaining fermentable sugars from starch in milled plant material at temperatures below the starch gelatinization temperature and using exogenous plant alpha amylases further to the fermentation of the sugars to produce end products, such as ethanol.
摘要翻译：本文描述的是淀粉水解方法，用于在低于淀粉糊化温度的温度下在研磨的植物材料中从淀粉中获得可发酵糖，并且使用外源植物α-淀粉酶进一步进行糖的发酵以产生最终产物如乙醇。

5. 发明申请

WO2010018105A1 DEGRADATION OF LIGNOCELLULOSIC MATERIAL 审中-公开
标题翻译：纤维素材料的降解
公开(公告)号：WO2010018105A1
公开(公告)日：2010-02-18
申请号：PCT/EP2009/060098
申请日：2009-08-04
申请人： DSM IP ASSETS B.V. , LAAT, DE, Wilhelmus Theodorus Antonius Maria , KUMAR, Manoj , SCHOONEVELD-BERGMANS, Margot, Elisabeth, Francoise
发明人： LAAT, DE, Wilhelmus Theodorus Antonius Maria , KUMAR, Manoj , SCHOONEVELD-BERGMANS, Margot, Elisabeth, Francoise
IPC分类号： C12P7/10 , C12P19/02 , C12R1/66
CPC分类号： C12P7/10 , C12P19/02 , C12P19/14 , C13K1/02 , Y02E50/16 , Y02E50/17
摘要： The present invention describes a method for the treatment of lignocellulosic material which method comprises contacting said lignocellulosic material with a composition comprising two or more enzyme activities, said enzyme activities being cellulase and/or hemicellulase activities, wherein the pH during the treatment is about 4.5 or lower, and the treatment is carried out at a dry matter content of 15% or more.
摘要翻译：本发明描述了一种用于处理木质纤维素材料的方法，该方法包括使所述木质纤维素材料与包含两种或多种酶活性的组合物接触，所述酶活性是纤维素酶和/或半纤维素酶活性，其中处理期间的pH为约4.5或更低，处理以干物质含量为15％以上进行。

6. 发明申请

WO2005065084A2 SYSTEM AND METHOD FOR PROVIDING ENCRYPTION IN PIPELINED STORAGE OPERATIONS IN A STORAGE NETWORK 审中-公开
标题翻译：在存储网络中管理存储操作中提供加密的系统和方法
公开(公告)号：WO2005065084A2
公开(公告)日：2005-07-21
申请号：PCT/US2004/038190
申请日：2004-11-15
申请人： COMMVAULT SYSTEMS, INC. , KUMAR, Manoj , PRASAD, Arun , KOTTOMTHARAYIL, Rajiv
发明人： KUMAR, Manoj , PRASAD, Arun , KOTTOMTHARAYIL, Rajiv
IPC分类号： G06F20060101 , G06F11/14 , G06F12/16
CPC分类号： G06F11/1469 , G06F11/1458 , G06F11/1464
摘要： In accordance with embodiments of the invention, a method is provided for performing a storage operation in a pipeline storage system in which one or more data streams containing data to be stored are written into data chunks. The method includes generating an encryption key associated with a first archive file to be stored when encryption is requested for the storage operation, encrypting the archive data from the data stream using the encryption key to create an encrypted data chunk when a data stream containing the archive file is processed in the pipeline storage system, storing the encrypted data chunk on a storage medium, and storing the encryption key in a manner accessible during a restore operation of the encrypted data chunk.
摘要翻译：根据本发明的实施例，提供了一种在流水线存储系统中执行存储操作的方法，其中将一个或多个包含要存储的数据的数据流写入数据块。该方法包括：当为存储操作请求加密时生成与要存储的第一归档文件相关联的加密密钥，使用加密密钥从数据流加密归档数据，以在包含存档的数据流时创建加密的数据块文件在流水线存储系统中处理，将加密的数据块存储在存储介质上，并且以加密数据块的恢复操作期间可访问的方式存储加密密钥。

7. 发明申请

WO2012137088A1 SYSTEM AND METHOD FOR HIERARCHICAL RECOVERY OF A CLUSTER FILE SYSTEM 审中-公开
标题翻译：用于分类文件系统的分层恢复的系统和方法
公开(公告)号：WO2012137088A1
公开(公告)日：2012-10-11
申请号：PCT/IB2012/051337
申请日：2012-03-21
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , IBM UNITED KINGDOM LIMITED , IBM (China) Investment Company Limited , GJERTSEN, Robert, Kenneth , KUMAR, Manoj , CRAFT, David, Jones , KANDIRAJU, Gokul, Bhargava
发明人： GJERTSEN, Robert, Kenneth , KUMAR, Manoj , CRAFT, David, Jones , KANDIRAJU, Gokul, Bhargava
IPC分类号： G06F15/173
CPC分类号： G06F17/30008 , G06F11/2025 , G06F11/2035
摘要： Hierarchical recovery of failed computing nodes to operative computing nodes within a cluster of computing nodes is managed by initiating a recovery leader at an operative node that retrieves management information from the operative nodes and applies the management information to recover filesets of a meta-fileset in a hierarchical filesystem. The use of hierarchical filesets throughout the cluster provides more rapid failover by 10 distributing recovery load across computing nodes and supporting recovery of nodes in parallel.
摘要翻译：通过启动在操作节点检索管理信息的操作节点处的恢复引导来管理故障计算节点到计算节点的集群内的操作计算节点的分级恢复，并应用管理信息来恢复元文件集的文件集分层文件系统。整个集群中使用分层文件集通过10个分布在计算节点之间的恢复负载并支持并行恢复节点来提供更快速的故障切换。

8. 发明申请

WO2009024998A1 NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL 审中-公开
标题翻译： PARACETAMOL的氮氧化物释放衍生物
公开(公告)号：WO2009024998A1
公开(公告)日：2009-02-26
申请号：PCT/IN2008/000514
申请日：2008-08-14
申请人： COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH , BHARDWAJ, Tilak, Raj , KUMAR, Manoj , MEHTA, Neeraj , DHINGRA, Neelima
发明人： BHARDWAJ, Tilak, Raj , KUMAR, Manoj , MEHTA, Neeraj , DHINGRA, Neelima
IPC分类号： C07C233/25 , A61P25/04 , A61P25/00 , A61K31/167
CPC分类号： C07C233/25
摘要： The present invention particularly relates to novel nitrate esters of paracetamol. The nitrate esters of paracetamol are prepared by reacting the paracetamol with dihaloalkyl compound and followed by reaction with silver nitrate to obtain the corresponding nitrate ester derivatives. The nitrate esters of paracetamol are useful as analgesic, anti-inflammatory agents.
摘要翻译：本发明特别涉及新型的扑热息痛的硝酸酯。对乙酰氨基酚的硝酸酯通过使对乙酰氨基酚与二卤代烷基化合物反应，随后与硝酸银反应得到相应的硝酸酯衍生物。对乙酰氨基酚的硝酸酯可用作止痛剂，抗炎剂。

9. 发明申请

WO2008051491A2 POLYOL OXIDASES 审中-公开
标题翻译：多环氧化物
公开(公告)号：WO2008051491A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/022372
申请日：2007-10-19
申请人： DANISCO US, INC. GENENCOR DIVISION , MADRID, Susan , KUMAR, Manoj , MCDONALD, Hugh, C. , POULOSE, Ayrookaran, J. , RAND, Thomas , WANG, Huaming
发明人： KUMAR, Manoj , MCDONALD, Hugh, C. , POULOSE, Ayrookaran, J. , RAND, Thomas , WANG, Huaming
IPC分类号： C12N1/00
CPC分类号： C12N9/0006 , C07K2319/00 , C07K2319/02 , C11D3/38636 , C11D3/38654 , C12N9/0004 , C12N9/0069
摘要： The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting.
摘要翻译：本发明提供用于在微生物中生产多元醇氧化酶的组合物和方法，以及在清洁组合物中使用多元醇氧化酶。本发明包括含有两种或更多种POx氧化酶的组合的清洁组合物和含有两种或更多种POx氧化酶和过水解酶的组合的清洁组合物。特别地，本发明提供了用于在洗涤剂应用中用于清洁，漂白和消毒的细菌宿主中表达多元氧化酶的方法。

10. 发明申请

WO2007024618A1 COMPOSITES OF REPEAT SEQUENCE PROTEINS AND THEIR PREPARATION 审中-公开
标题翻译：重复序列蛋白的复合物及其制备
公开(公告)号：WO2007024618A1
公开(公告)日：2007-03-01
申请号：PCT/US2006/032114
申请日：2006-08-17
申请人： GENENCOR INTERNATIONAL, INC. , KUMAR, Manoj
发明人： KUMAR, Manoj
IPC分类号： C08K5/00 , C08K3/22 , C08L89/00 , C08J5/18
CPC分类号： C08K5/0016 , C08J3/215 , C08J5/10 , C08J2389/00 , C08L71/02 , C08L89/00 , Y10T428/249921 , C08L2666/22
摘要： A composite of one or more repeat sequence protein polymers and either one or more metal oxides or one or more plasticizers alters material properties of the repeat sequence protein polymers, including the morphology of the polymers as well as the elastic modulus and tensile strength. The morphology of the composite is aligned, generally parallel nanofibers.
摘要翻译：一种或多种重复序列蛋白质聚合物和一种或多种金属氧化物或一种或多种增塑剂的复合物改变重复序列蛋白质聚合物的材料性质，包括聚合物的形态以及弹性模量和拉伸强度。将复合材料的形态对准，一般平行的纳米纤维。

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