会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 9. 发明申请
    • NOVEL PROTEINS AND NUCLEIC ACIDS ENCODING SAME
    • 新蛋白质和编码相同的核酸
    • WO03004687A8
    • 2003-05-08
    • PCT/US0221361
    • 2002-07-03
    • CURAGEN CORPANDERSON DAVID WBERGHS CONSTANCEBOLDOG FERENC LBURGESS CATHERINE ECASMAN STACIE JCATTERTON ELINA
    • ANDERSON DAVID WBERGHS CONSTANCEBOLDOG FERENC LBURGESS CATHERINE ECASMAN STACIE JCATTERTON ELINA
    • C07K14/47C12Q
    • C07K14/47
    • The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    • 本发明提供了由多核苷酸编码的新的分离的多核苷酸和小分子靶多肽。 公开了免疫特异性结合新型小分子靶多肽或该多肽,多核苷酸或抗体的任何衍生物,变体,突变体或片段的抗体,其中小分子靶多肽,多核苷酸和抗体用于检测和 治疗广泛的病理状态。 更具体地,本发明公开了在各种筛选过程中使用重组表达的和/或内源表达的蛋白质以鉴定治疗性抗体和与疾病相关的治疗性小分子的方法。 本发明还公开了与疾病相关的治疗性小分子。 本发明进一步公开了用于诊断,治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗,诊断和研究方法。