专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2004035798A2 IDENTIFICATION OF NOVEL E2F TARGET GENES AND USE THEREOF 审中-公开
标题翻译：鉴定E2F目标基因及其用途
公开(公告)号：WO2004035798A2
公开(公告)日：2004-04-29
申请号：PCT/EP0311658
申请日：2003-10-20
申请人： CROPDESIGN NV , INZE DIRK , DE VEYLDER LIEVEN , VLIEGHE KOBE
发明人： INZE DIRK , DE VEYLDER LIEVEN , VLIEGHE KOBE
IPC分类号： A01H1/04 , A01H5/00 , A61K31/713 , A61K38/16 , C07K14/415 , C12N15/82
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The present invention concerns a method for altering characteristics of a plant. The invention describes the identification of genes that are upregulated or downregulated in transgenic plants overexpressing E2Fa/DPa and the use of such sequences to alter plant characteristics. A preferred way for altering characteristics of a plant comprises modifying expression of one or more nucleic acid sequences and or modifying level and/or activity of one or more proteins, which nucleic acids and/or proteins are essentially similar to any one or more of SEQ ID NO 1 to 2755. Some of the genes identified in the present invention have an E2Fa target consensus sequence in their 5' upstream region. The identified genes play a role in a variety of biological processes, such as DNA replication, cell wall biosynthesis, nitrogen and/or carbon metabolism, transcription factors etc.
摘要翻译：本发明涉及改变植物特性的方法。本发明描述了在过表达E2Fa / DPa的转基因植物中上调或下调的基因的鉴定，以及使用这种序列改变植物特征。用于改变植物特征的优选方法包括修饰一个或多个核酸序列的表达和/或修饰一种或多种蛋白质的水平和/或活性，所述核酸和/或蛋白质基本上类似于SEQ ID NO： ID NO 1至2755.本发明中鉴定的一些基因在其5'上游区具有E2Fa靶共有序列。鉴定的基因在多种生物过程中起作用，如DNA复制，细胞壁生物合成，氮和/或碳代谢，转录因子等。

2. 发明申请

WO02053589A3 NUCLEIC ACID MOLECULES ENCODING DIM INTERACTORS AND USES THEREFOR 审中-公开
标题翻译：编码DIM相互作用的核酸分子及其用途
公开(公告)号：WO02053589A3
公开(公告)日：2002-11-07
申请号：PCT/EP0200073
申请日：2002-01-07
申请人： CROPDESIGN NV , DE VEYLDER LIEVEN , BOUDOLF VERONIQUE KATELIJNE CE , INZE DIRK , FRANKARD VALERIE MARIE-NOELLE , TERRAS FRANKY
发明人： DE VEYLDER LIEVEN , BOUDOLF VERONIQUE KATELIJNE CE , INZE DIRK , FRANKARD VALERIE MARIE-NOELLE , TERRAS FRANKY
IPC分类号： C07K14/415 , C12N15/82 , C07K16/16 , C12N5/10 , C12N15/11 , C12N15/62 , C12Q1/68 , G01N33/50
CPC分类号： C12N15/8261 , C07K14/415 , C12N15/8271 , C12N15/8279 , Y02A40/146
摘要： The invention provides isolated nucleic acids molecules, designated DIM1 interacting molecules (DIMIC) molecules, which encode novel cell cycle associated polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DIMIC nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which a DIMIC gene has been introduced or disrupted. The invention still further provides isolated DIMIC proteins, fusion proteins, antigenic peptides and anti-DIMIC antibodies. Agricultural, and screening methods utilizing molecules and compositions of the invention are also provided. The invention further provides methods for modulating overall growth and yield in a plant, enhancing stress tolerance of a plant, conferring enhanced resistance to pathogens to a plant, modulating pre-mRNA splicing in a plant cell, or modulating vesicle transport/processing in a plant cell, comprising introducing into the plant or plant cell a DIMIC molecule or DIMIC modulator, alone or in combination with a DIM1 molecule.
摘要翻译：本发明提供了编码新的细胞周期相关多肽的分离的核酸分子，称为DIM1相互作用分子（DIMIC）分子。本发明还提供反义核酸分子，含有DIMIC核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及引入或破坏DIMIC基因的转基因植物。本发明还进一步提供了分离的DIMIC蛋白，融合蛋白，抗原肽和抗DIMIC抗体。还提供了利用本发明的分子和组合物的农业和筛选方法。本发明还提供调节植物总体生长和产量的方法，增强植物的胁迫耐受性，赋予对植物病原体的增强的抗性，调节植物细胞中的mRNA前剪接或调节植物中的囊泡转运/加工包括单独或与DIM1分子组合引入到植物或植物细胞中的DIMIC分子或DIMIC调节剂。

3. 发明申请

WO03018818A8 METHOD AND MEANS FOR MODULATING PLANT CELL CYCLE PROTEINS AND THEIR USE IN PLANT CELL GROWTH CONTROL 审中-公开
公开(公告)号：WO03018818A8
公开(公告)日：2003-05-22
申请号：PCT/EP0209504
申请日：2002-08-26
申请人： CROPDESIGN NV , DE VEYLDER LIEVEN , INZE DIRK , MIRONOV VLADIMIR , SEGERS GERDA
发明人： DE VEYLDER LIEVEN , INZE DIRK , MIRONOV VLADIMIR , SEGERS GERDA
IPC分类号： C07K14/415 , C12N15/82 , A01H5/00
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The present invention relates to modulation of endoreduplication in a plant or part thereof which may be achieved by modifying expression or activity of E2F or E2F in combination with DP.Modulation of endoreduplication has an advantageous influence on plant cell size and storage capacity of plant cells.

4. 发明申请

WO03018818A3 METHOD AND MEANS FOR MODULATING PLANT CELL CYCLE PROTEINS AND THEIR USE IN PLANT CELL GROWTH CONTROL 审中-公开
标题翻译：调节植物细胞周期蛋白的方法和手段及其在植物细胞生长控制中的用途
公开(公告)号：WO03018818A3
公开(公告)日：2003-09-04
申请号：PCT/EP0209504
申请日：2002-08-26
申请人： CROPDESIGN NV , DE VEYLDER LIEVEN , INZE DIRK , MIRONOV VLADIMIR , SEGERS GERDA
发明人： DE VEYLDER LIEVEN , INZE DIRK , MIRONOV VLADIMIR , SEGERS GERDA
IPC分类号： C07K14/415 , C12N15/82 , A01H5/00
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The present invention relates to modulation of endoreduplication in a plant or part thereof which may be achieved by modifying expression or activity of E2F or E2F in combination with DP.Modulation of endoreduplication has an advantageous influence on plant cell size and storage capacity of plant cells.
摘要翻译：本发明涉及通过修饰E2F或E2F与DP组合的表达或活性而实现的植物或其部分中的内部复制的调节。内部复制的调节对植物细胞的大小和储存能力具有有利的影响。

5. 发明申请

WO0185946A3 NUCLEIC ACID MOLECULES ENCODING PLANT CELL CYCLE PROTEINS AND USES THEREFOR 审中-公开
标题翻译：核酸分子编码植物细胞周期蛋白及其用途
公开(公告)号：WO0185946A3
公开(公告)日：2003-03-13
申请号：PCT/IB0101307
申请日：2001-05-14
申请人： CROPDESIGN NV , INZE DIRK , BOUDOLF VERONIQUE , DE VEYLDER LIEVEN , ACOSTA JUAN ANTONIO TORRES , MAGYAR ZOLTAN
发明人： INZE DIRK , BOUDOLF VERONIQUE , DE VEYLDER LIEVEN , ACOSTA JUAN ANTONIO TORRES , MAGYAR ZOLTAN
IPC分类号： A01H5/00 , C07K14/415 , C07K16/16 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/29 , C12N15/82 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/53 , G01N33/68
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The invention provides isolated nucleic acids molecules, designated CCP nucleic acid molecules, which encode novel cell cycle associated polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CCP nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which a CCP gene has been introduced or disrupted. The invention still further provides isolated CCP proteins, fusion proteins, antigenic peptides and anti-CCP antibodies. Agricultural, diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的细胞周期相关多肽的分离的核酸分子，命名为CCP核酸分子。本发明还提供了反义核酸分子，含有CCP核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及CCP基因被引入或破坏的转基因植物。本发明还进一步提供了分离的CCP蛋白，融合蛋白，抗原肽和抗CCP抗体。还提供了利用本发明组合物的农业，诊断，筛选和治疗方法。

6. 发明申请

WO0036124A3 PLANT CELL CYCLE GENES AND USES THEREOF 审中-公开
标题翻译：植物细胞周期基因及其用途
公开(公告)号：WO0036124A3
公开(公告)日：2000-11-23
申请号：PCT/EP9910084
申请日：1999-12-17
申请人： CROPDESIGN NV , VEYLDER LIEVEN DE , BOUDOLF VERONIQUE KATELIJNE CE , TORRES ACOSTA JUAN ANTONIO , INZE DIRK
发明人： DE VEYLDER LIEVEN , BOUDOLF VERONIQUE KATELIJNE CE , TORRES ACOSTA JUAN ANTONIO , INZE DIRK
IPC分类号： A01H5/00 , A61K38/00 , A61K38/16 , A61K39/00 , C07K14/415 , C07K16/16 , C12N1/20 , C12N15/11 , C12N15/82 , C12Q1/68 , G01N33/50
CPC分类号： C12N15/8229 , A61K38/00 , C07K14/415 , C12N15/8241
摘要： Provided are DNA sequences encoding cell cycle interacting proteins as well as methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences preferably are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cell cycle regulatory proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Also provided are regulatory sequences controling the expression of the above described cell cycle interacting proteins. Method for the identification of compounds being capable of activating or inhibiting the cell cycle are described as well. Furhter described are diagnostic compositions comprising the aforementioned DNA sequences, regulatory sequences, proteins, antibodies, inhibitors and activators. Furthermore, transgenic plant cells, plant tissue and plants containing the above-described DNA sequences and vectors are described as well as the use of the aforementioned DNA sequences, vectors, proteins, regulatory sequences, antibodies and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.
摘要翻译：提供编码细胞周期相互作用蛋白质的DNA序列以及获得该DNA序列的方法。此外，描述了包含所述DNA序列的载体，其中所述DNA序列优选可操作地连接到允许在原核和/或真核宿主细胞中表达的调节元件。此外，提供了由所述DNA序列编码的蛋白质，对所述蛋白质的抗体及其生产方法。还描述了一种用于控制或改变植物和/或植物细胞的生长特性的方法，包括在植物或其部分中引入和/或表达一种或多种功能的细胞周期调节蛋白和/或编码这样的蛋白质。还提供了控制上述细胞周期相互作用蛋白的表达的调节序列。还描述了用于鉴定能够激活或抑制细胞周期的化合物的方法。描述的是包含上述DNA序列，调节序列，蛋白质，抗体，抑制剂和激活剂的诊断组合物。此外，描述了含有上述DNA序列和载体的转基因植物细胞，植物组织和植物以及上述DNA序列，载体，蛋白质，调节序列，抗体和/或通过在植物细胞和组织培养，植物育种和/或农业中的发明。

7. 发明申请

WO0120020A3 METHOD TO IDENTIFY HERBICIDES, FUNGICIDES OR PLANT GROWTH REGULATORS 审中-公开
标题翻译：鉴定除草剂，杀真菌剂或植物生长调节剂的方法
公开(公告)号：WO0120020A3
公开(公告)日：2001-09-27
申请号：PCT/EP0008797
申请日：2000-09-08
申请人： CROPDESIGN NV , BOUNAGA SAKINA , INZE DIRK , VEYLDER LIEVEN DE , MIRONOV VLADIMIR
发明人： BOUNAGA SAKINA , INZE DIRK , DE VEYLDER LIEVEN , MIRONOV VLADIMIR
IPC分类号： C07K14/415 , C12N15/81 , C12Q1/02 , C12Q1/18 , A01H5/00 , A01N65/00 , C07K14/39 , C12N15/29 , C12N15/82
CPC分类号： C07K14/415 , C12N15/81 , C12Q1/025 , C12Q1/18
摘要： The present invention relates to a method for screening and identification of compounds or compositions useful as herbicides, growth regulators or fungicides involving at least the following steps of addition of the compound or composition to be screened or identified to a culture or culture area of a yeast strain transformed with and expressing one or more plant cell cycle control genes or mutants thereof (phytoyeast) as well as to a control yeast strain; and, determining the effect on the phenotype (growth and/or cell division and/or cell size/shape) of said phytoyeast compared to said control yeast. The invention further relates to a bilogical screening assay (high throughput system) comprising the use of said phytoyeast expressing plant cell cycle control proteins to identify novel compounds or compositions that affect control yeast or phytoyeast phenotype. The present invention also relates to methods for producing a pesticide, herbicide, plant growth regulator or fungicide, comprising the steps of (a) identifying a compound or composition as defined above or a derivative or homologue thereof, and, (b) mixing said compound, composition, derivative or homologue thereof with an acceptable carrier. The invention also relates to the use of said compounds or compositions for inhibiting or stimulating plant growth and/or for increasing crop yield and/or for preventive or curative protection of the plant against fungal infection.
摘要翻译：本发明涉及用于筛选和鉴定用作除草剂，生长调节剂或杀真菌剂的化合物或组合物的方法，该方法至少包括以下步骤：将要筛选或鉴定的化合物或组合物添加到酵母的培养或培养区域用一种或多种植物细胞周期控制基因或其突变体（植物药）转化并表达的菌株以及对照酵母菌株; 并且与所述对照酵母相比，确定对所述植物淀粉的表型（生长和/或细胞分裂和/或细胞大小/形状）的影响。本发明还涉及生物筛选测定（高通量系统），其包括使用表达植物树脂的植物细胞周期控制蛋白来鉴定影响对照酵母或植物性表型的新化合物或组合物。本发明还涉及生产农药，除草剂，植物生长调节剂或杀真菌剂的方法，其包括以下步骤：（a）鉴定上述化合物或组合物或其衍生物或同系物，和（b）将所述化合物，组合物，衍生物或同系物与可接受的载体。本发明还涉及所述化合物或组合物用于抑制或刺激植物生长和/或增加作物产量和/或预防或治疗保护植物免受真菌感染的用途。

8. 发明申请

WO2004065596A3 USE OF THE REGULATORY SEQUENCE OF THE RICE GOS2 GENE FOR THE GENE EXPRESSION IN DICOTYLEDONOUS PLANTS OR PLANT CELLS 审中-公开
标题翻译：使用稻米GOS2基因在二倍体植物或植物细胞中的基因表达的调节序列
公开(公告)号：WO2004065596A3
公开(公告)日：2004-09-30
申请号：PCT/EP2004000645
申请日：2004-01-21
申请人： CROPDESIGN NV , HATZFELD YVES , INZE DIRK
发明人： HATZFELD YVES , INZE DIRK
IPC分类号： C12N15/82
CPC分类号： C12N15/8216
摘要： The present invention relates to the field of plant molecular biology. In particular, it describes the use of a regulatory nucleic acid sequence of the rice gene GOS2 for the regulation of gene expression in plant cells derived from plants other than monocotyledonous plants. The use of the regulatory sequence of the present invention results in constitutive expression with expression levels similar to that of CaMV 35S. The present invention also relates to vectors and host cells comprising these nucleic acid sequences. The invention further relates to transgenic cells and plants comprising these sequences and to methods for obtaining such cells and plants.
摘要翻译：本发明涉及植物分子生物学领域。特别地，其描述了水稻基因GOS2的调节性核酸序列用于调节来自除单子叶植物以外的植物的植物细胞中的基因表达的用途。使用本发明的调节序列导致表达水平与CaMV 35S相似的组成型表达。本发明还涉及包含这些核酸序列的载体和宿主细胞。本发明还涉及包含这些序列的转基因细胞和植物以及获得这种细胞和植物的方法。

9. 发明申请

WO0228893A2 NOVEL PLANT CYCLIN-DEPENDENT KINASE INHIBITORS 审中-公开
标题翻译：新型植物依赖性激酶抑制剂
公开(公告)号：WO0228893A2
公开(公告)日：2002-04-11
申请号：PCT/IB0101492
申请日：2001-06-29
申请人： CROPDESIGN NV , FRANKARD VALERIE MARIE NOELLE , PERES BOTA ADRIAN MARIUS , DROUAL ANNE MARIE , MIRONOV VLADIMIR , INZE DIRK , HATZFELD YVES
发明人： FRANKARD VALERIE MARIE-NOELLE , PERES BOTA ADRIAN MARIUS , DROUAL ANNE-MARIE , MIRONOV VLADIMIR , INZE DIRK , HATZFELD YVES
IPC分类号： C07K14/415 , C12N15/54 , C12N15/82 , C07K14/47 , A01H5/00 , C07K16/40 , C12N9/12 , G01N33/573
CPC分类号： C07K14/415 , C12N15/8261 , C12N15/8273 , Y02A40/146
摘要： The invention provides isolated nucleic acids molecules, designated ICK nucleic acid molecules, which encode novel plant cyclin-dependent kinase inhibitors. The invention also provides antisense nucleic acid molecules, gene silencing and recombinant expression vectors containing ICK nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which an ICK gene has been introduced or disrupted. The invention still further provides isolated ICK proteins, fusion proteins, antigenic peptides and anti-ICK antibodies. Agricultural, diagnostic, and screening methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的植物细胞周期蛋白依赖性激酶抑制剂的分离的核酸分子，称为ICK核酸分子。本发明还提供了含有ICK核酸分子的反义核酸分子，基因沉默和重组表达载体，其中引入了表达载体的宿主细胞，以及引入或破坏ICK基因的转基因植物。本发明还进一步提供了分离的ICK蛋白，融合蛋白，抗原肽和抗ICK抗体。还提供了利用本发明组合物的农业，诊断和筛选方法。

10. 发明申请

WO9913083A9 METHOD AND MEANS FOR MODULATING PLANT CELL CYCLE PROTEINS AND THEIR USE IN CONTROLLING PLANT CELL GROWTH 审中-公开
标题翻译：调节植物细胞周期蛋白的方法和手段及其在控制植物细胞生长中的应用
公开(公告)号：WO9913083A9
公开(公告)日：2001-03-29
申请号：PCT/EP9805673
申请日：1998-09-07
申请人： CROPDESIGN NV , INZE DIRK , SEGERS GERDA , VEYLDER LIEVEN DE
发明人： INZE DIRK , SEGERS GERDA , DE VEYLDER LIEVEN
IPC分类号： A01H5/00 , A01N61/00 , A01N65/08 , C07K14/415 , C07K16/16 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/29 , C12N15/82 , C12P21/02 , G01N33/15 , G01N33/50 , G01N33/53 , A01N65/00
CPC分类号： A01N65/08 , A01N65/00 , C07K14/415 , C12N15/8261 , Y02A40/146 , A01N2300/00
摘要： Provided are DNA sequences encoding cell cycle interacting proteins as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cell cycle regulatory proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Also provided is a process for disruption plant cell division by interfering in the expression of a substrate for cyclin-dependent protein kinase using a DNA sequence according to the invention wherein said plant cell is part of a transgenic plant. Further described are diagnostic compositions comprising the aforementioned DNA sequences, proteins and antibodies. Methods for the identification of compounds being capable of activating or inhibiting the cell cycle are described as well. Furthermore, transgenic plant cells, plant tissue and plants containing the above-described DNA sequences and vectors are described as well as the use of the aforementioned DNA sequences, vectors, proteins, antibodies and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.
摘要翻译：提供编码细胞周期相互作用蛋白质的DNA序列以及获得该DNA序列的方法。此外，描述了包含所述DNA序列的载体，其中所述DNA序列可操作地连接到允许在原核和/或真核宿主细胞中表达的调节元件。此外，提供了由所述DNA序列编码的蛋白质，对所述蛋白质的抗体及其生产方法。还描述了一种用于控制或改变植物和/或植物细胞的生长特性的方法，包括在植物或其部分中引入和/或表达一种或多种功能的细胞周期调节蛋白和/或编码这样的蛋白质。还提供了使用根据本发明的DNA序列干扰细胞周期蛋白依赖性蛋白激酶底物的表达来破坏植物细胞分裂的方法，其中所述植物细胞是转基因植物的一部分。进一步描述包括上述DNA序列，蛋白质和抗体的诊断组合物。还描述了用于鉴定能够激活或抑制细胞周期的化合物的方法。此外，描述了含有上述DNA序列和载体的转基因植物细胞，植物组织和植物以及通过本发明的方法鉴定的上述DNA序列，载体，蛋白质，抗体和/或化合物在植物中的用途细胞和组织培养，植物育种和/或农业。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式