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1. 发明申请

WO2007072424A3 OPTICAL PROBE DESIGN 审中-公开
标题翻译：光学探针设计
公开(公告)号：WO2007072424A3
公开(公告)日：2007-10-25
申请号：PCT/IB2006054951
申请日：2006-12-19
申请人： CRITISENSE LTD , PEWZNER ELIAHU , DEUTSCH ASSAF , BLUM YORAM , MAYEVSKY AVRAHAM
发明人： PEWZNER ELIAHU , DEUTSCH ASSAF , BLUM YORAM , MAYEVSKY AVRAHAM
IPC分类号： A61B5/00
CPC分类号： A61B5/0261 , A61B5/0059 , A61B5/0084 , A61B5/14546 , A61B5/1455 , A61B5/412 , A61B5/7214 , A61B2562/0242 , A61B2562/08
摘要： An optical probe, for acquiring measurements of material in a surface, the probe comprising: a probe body; at least one illuminating optical fiber that transmits light to a distal end thereof to illuminate a region of the surface and interact with the material; and at least one receiving optical fiber, positioned to receive light that has been transmitted by the illuminating fiber to the region and has interacted with the material, which received light is used for acquiring the measurements, the receiving fiber thereby being defined as associated with the illuminating fiber; wherein at least one of the fibers has a portion inside the probe body with a bend.
摘要翻译：一种用于获取表面中的材料的测量的光学探针，所述探针包括：探针体; 至少一个照明光纤，其将光透射到其远端以照亮所述表面的区域并与所述材料相互作用; 并且至少一个接收光纤被定位成接收已经被照明光纤传输到该区域并且与接收光的材料相互作用的光已被用于获取测量值，因此接收光纤被定义为与照明纤维; 其中所述纤维中的至少一个在所述探针体内具有弯曲部分。

2. 发明申请

WO2012176071A2 METHODS AND APPARATUS FOR REDUCING COUNT OF INFECTIOUS AGENTS IN INTRAVENOUS ACCESS SYSTEMS 审中-公开
标题翻译：用于减少感染系统中感染细胞数量的方法和装置
公开(公告)号：WO2012176071A2
公开(公告)日：2012-12-27
申请号：PCT/IB2012001898
申请日：2012-05-11
申请人： HAYTMAN EYAL , DEUTSCH ASSAF , PEWZNER ELIAHU , BACTRIBLUE LTD
发明人： HAYTMAN EYAL , DEUTSCH ASSAF , PEWZNER ELIAHU
IPC分类号： A61N5/06
CPC分类号： A61N5/0624 , A61N2005/0645 , A61N2005/0662 , A61N2005/0663
摘要： An apparatus for preventing infection at a catheter insertion site. The apparatus has a U-shaped housing comprising a cross-bar and a pair of arms extending from said cross-bar, and light-emitting elements for irradiating a catheter insertion site with light having wavelengths in an anti-microbial range. The U-shaped housing has a diagonal surface from which one or more of the light-emitting elements extend, and the light-emitting elements are positioned such that they emit light in a direction below the housing while operational. The device may be affixed over a transparent dressing overlying the catheter entry point. The device may be affixed to the catheter insertion site using an adhesive or fastening band, or through other methods. The light sources may be positioned such that light from the light sources overlaps at one or more areas on the skin, especially the catheter entry point.
摘要翻译：一种用于防止导管插入部位感染的装置。该装置具有U形外壳，其包括横杆和从所述横杆延伸的一对臂以及用于用具有抗微生物范围波长的光照射导管插入位点的发光元件。 U形壳体具有一个或多个发光元件从该对角表面延伸，并且发光元件被定位成使得它们在操作时沿着壳体下方的方向发光。该装置可以固定在覆盖导管入口点的透明敷料上。该装置可以使用粘合剂或紧固带或通过其它方法固定到导管插入部位。光源可以被定位成使得来自光源的光在皮肤上的一个或多个区域重叠，特别是导管入口点。

3. 发明申请

WO2007074449A3 SUBSTANTIALLY INVISIBLE THREE-DIMENSIONAL STRUCTURE FOR THE STUDY OF CELLS 审中-公开
标题翻译：实质研究细胞的三维结构
公开(公告)号：WO2007074449A3
公开(公告)日：2007-11-15
申请号：PCT/IL2006001487
申请日：2006-12-26
申请人： SENG ENTPR LTD , DEUTSCH MORDECHAI , DEUTSCH ASSAF
发明人： DEUTSCH MORDECHAI , DEUTSCH ASSAF
IPC分类号： G01N33/50 , B01L3/00 , C12M3/00
CPC分类号： B01L3/5085 , B01L2200/12 , B01L2300/0654 , B01L2300/069 , B01L2300/0829 , B01L2300/12 , G01N33/5005
摘要： A device (10) for the study of cells comprising a structure (18) with an index of refraction similar to that of water having a three-dimensional arrangement of fluid channels is disclosed. Also disclosed is a method for studying cells comprising seeding a structure (18) with an index of refraction similar to that of water having a three-dimensional arrangement of fluid channels with viable cells, immersing the structure (18) in a physiological medium (14), and observing the development of the seeded cells inside the structure.
摘要翻译：公开了一种用于研究细胞的装置（10），其包括具有类似于具有流体通道的三维布置的水的折射率的结构（18）。还公开了一种用于研究细胞的方法，包括将折射率类似于具有活细胞的三维排列流体通道的水的结构（18）接种，将结构（18）浸入生理介质（14）），观察结构内种子细胞的发育情况。

4. 发明申请

WO2008078326A3 DEVICE FOR STUDYING CELLS OF THIXOTROPIC MATERIAL AND METHOD OF MANUFACURE THEREOF 审中-公开
标题翻译：用于研究双相材料的细胞的装置及其制造方法
公开(公告)号：WO2008078326A3
公开(公告)日：2008-08-14
申请号：PCT/IL2007001607
申请日：2007-12-25
申请人： SENG ENTPR LTD , DEUTSCH MORDECHAI , DEUTSCH ASSAF
发明人： DEUTSCH MORDECHAI , DEUTSCH ASSAF
IPC分类号： B01L3/00
CPC分类号： B01L3/5085 , B01L2200/12 , B01L2300/0809 , B01L2300/0829 , B01L2300/0887 , B01L2300/0893
摘要： Provided in some embodiments are novel planar well-bearing components made of a thixotropic material, the components having a relatively homogeneous thickness, and on which a surface is located an array of wells, where the bottoms of the individual wells of a component being relatively coplanar, each well of a size and shape suitable for retaining a cell therein. Provided in some embodiments are novel methods for producing a planar well-bearing component useful for holding and studying living cells including impressing a well-array into a surface of a thixotropic material.
摘要翻译：在一些实施例中提供了由触变材料制成的新颖的平面承载部件，所述部件具有相对均匀的厚度，并且其上的表面位于孔阵列上，其中部件的各个孔的底部相对共面每个孔的尺寸和形状适合于在其中保留电池。在一些实施方案中提供了用于生产用于保持和研究活细胞的平面有益部件的新颖方法，包括将阵列施加到触变材料的表面中。

5. 发明申请

WO2009063462A3 PICO LITER WELL HOLDING DEVICE AND METHOD OF MAKING THE SAME 审中-公开
标题翻译： PICO LITER井保持装置及其制造方法
公开(公告)号：WO2009063462A3
公开(公告)日：2010-03-11
申请号：PCT/IL2008001492
申请日：2008-11-13
申请人： SENG ENTPR LTD , DEUTSCH MORDECHAI , DEUTSCH ASSAF
发明人： DEUTSCH MORDECHAI , DEUTSCH ASSAF
IPC分类号： C12M3/00
CPC分类号： B01L3/5027 , B01L3/502715 , B01L3/5085 , B01L2200/027 , B01L2200/0668 , B01L2300/041 , B01L2300/0809 , B01L2300/0822 , B01L2300/0887 , B01L2300/0893 , B01L2300/123 , B01L2400/0406 , C12M23/12 , C12M23/22 , Y10T29/49826
摘要： Described herein are embossing methods for forming pico liter well arrays (and other structures), arrangements of such pico liter well arrays, for example, in arrays of pico liter well areas, and methods of forming templates for such embossing. Also described as wells with a refractive index similar to that of an aqueous medium used for supporting cells in the wells.
摘要翻译：这里描述的是用于形成微微公升阵列（和其它结构）的压花方法，这种pico升阵列的布置，例如以pico升井区域阵列，以及形成用于这种压花的模板的方法。还描述为具有类似于用于支撑孔中的细胞的水性介质的折射率的孔。

6. 发明申请

WO2006021959A2 METHOD AND DEVICE FOR ISOLATING CELLS 审中-公开
标题翻译：用于分离细胞的方法和装置
公开(公告)号：WO2006021959A2
公开(公告)日：2006-03-02
申请号：PCT/IL2005000914
申请日：2005-08-24
申请人： MOLECULAR CYTOMICS LTD , DEUTSCH ASSAF , DEUTSCH MORDECHAI
发明人： DEUTSCH ASSAF , DEUTSCH MORDECHAI
IPC分类号： B01J19/00 , G01N15/14
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00317 , B01J2219/00441 , B01J2219/00711 , B01J2219/00716 , B01J2219/00743 , B01L3/502761 , B01L2200/0668 , B01L2300/0877 , B01L2300/16 , G01N35/00029 , G01N2035/00158
摘要： A method for selecting specific cells from amongst a group of cells and a device for implementing the method, the method including the use of a radiation sensitive medium having a first state that does not immobilize cells and a second state that immobilizes cells wherein the radiation sensitive medium locally transforms from the first state to the second state upon exposure to radiation.
摘要翻译：一种用于从一组细胞中选择特定细胞的方法和一种用于实施该方法的装置，该方法包括使用具有不固定细胞的第一状态的辐射敏感介质和固定细胞的第二状态，其中辐射敏感的当暴露于辐射时，介质从第一状态局部转变为第二状态。

7. 发明申请

WO2009081409A3 DEVICE FOR THE STUDY OF LIVING CELLS 审中-公开
标题翻译：活体细胞研究装置
公开(公告)号：WO2009081409A3
公开(公告)日：2009-11-05
申请号：PCT/IL2008001678
申请日：2008-12-25
申请人： SENG ENTPR LTD , DEUTSCH MORDECHAI , DEUTSCH ASSAF
发明人： DEUTSCH MORDECHAI , DEUTSCH ASSAF
IPC分类号： B01L3/00
CPC分类号： B01L3/5027 , B01L3/502715 , B01L3/5085 , B01L2200/027 , B01L2200/0668 , B01L2300/041 , B01L2300/0809 , B01L2300/0822 , B01L2300/0887 , B01L2300/0893 , B01L2300/123 , B01L2400/0406 , C12M23/12 , C12M23/22 , Y10T29/49826
摘要： A cell study device, comprising, a base layer, a planar conduit defining layer, including a conduit cut out of the layer; and a planar cover layer which defines a capillary flow channel in said conduit layer, said conduit layer and said cover layer acting as side walls for said capillary flow channel, wherein said layers are formed of materials that do not interfere with cell behavior over a period of at least 5 hours when loaded with aqueous solution.
摘要翻译：一种细胞研究装置，包括：基层，平面导管限定层，包括从所述层切出的导管; 以及在所述导管层中限定毛细管流动通道的平面覆盖层，所述导管层和所述覆盖层用作所述毛细管流动通道的侧壁，其中所述层由在一段时间内不干扰细胞行为的材料形成在装载水溶液时至少5小时。

8. 发明申请

WO2006021959A9 Method and device for isolating cells 审中-公开
标题翻译：隔离细胞的方法和装置
公开(公告)号：WO2006021959A9
公开(公告)日：2006-05-11
申请号：PCT/IL2005000914
申请日：2005-08-24
申请人： DEUTSCH ASSAF , DEUTSCH MORDECHAI , MOLECULAR CYTOMICS LTD
发明人： DEUTSCH ASSAF , DEUTSCH MORDECHAI
IPC分类号： B01J19/00 , G01N15/14
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00317 , B01J2219/00441 , B01J2219/00711 , B01J2219/00716 , B01J2219/00743 , B01L3/502761 , B01L2200/0668 , B01L2300/0877 , B01L2300/16 , G01N35/00029 , G01N2035/00158
摘要： A method for selecting specific cells from amongst a group of cells and a device for implementing the method, the method including the use of a radiation sensitive medium having a first state that does not immobilize cells and a second state that immobilizes cells wherein the radiation sensitive medium locally transforms from the first state to the second state upon exposure to radiation.
摘要翻译：一种用于从一组细胞中选择特定细胞的方法和用于实施该方法的装置，所述方法包括使用具有不固定细胞的第一状态的辐射敏感介质和固定细胞的第二状态，其中辐射敏感介质在暴露于辐射时从第一状态转换到第二状态。

9. 发明申请

WO2005007796A3 IMPROVED MULTIWELL PLATE 审中-公开
标题翻译：改进的多层板
公开(公告)号：WO2005007796A3
公开(公告)日：2005-04-14
申请号：PCT/IL2004000661
申请日：2004-07-20
申请人： MOLECULAR CYTOMICS LTD , DEUTSCH MORDECHAI , HERZBERG MAX , TIROSH REUVEN , DEUTSCH ASSAF
发明人： DEUTSCH MORDECHAI , HERZBERG MAX , TIROSH REUVEN , DEUTSCH ASSAF
IPC分类号： C12M20060101 , C12M3/00 , C12N5/00
CPC分类号： B01L3/5085 , B01L3/5027 , B01L2200/0668 , B01L2200/12 , B01L2300/0636 , B01L2300/069 , B01L2300/0829 , B01L2300/0851 , C12M23/12
摘要： A multiwell plate (52) having a plurality of picowells (46) on the bottom of the wells of the plate as well as methods of producing the multiwell plate are provided. Provided is also a method of handling living cells (48) by providing an ordered array of living cells immobilized in a non-fluid matrix, contacting the living cells with a stimulus; and detecting a response to the stimulus. The present invention is also of a method of producing an ordered array of living cells.
摘要翻译：提供了在板的孔的底部具有多个小皮毛（46）的多孔板（52）以及制造多孔板的方法。还提供了通过提供固定在非流体基质中的活细胞的有序阵列来接触活细胞与刺激物来处理活细胞（48）的方法; 并检测对刺激的响应。本发明也是生产活细胞有序阵列的方法。

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