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1. 发明申请

WO2007072424A3 OPTICAL PROBE DESIGN 审中-公开
标题翻译：光学探针设计
公开(公告)号：WO2007072424A3
公开(公告)日：2007-10-25
申请号：PCT/IB2006054951
申请日：2006-12-19
申请人： CRITISENSE LTD , PEWZNER ELIAHU , DEUTSCH ASSAF , BLUM YORAM , MAYEVSKY AVRAHAM
发明人： PEWZNER ELIAHU , DEUTSCH ASSAF , BLUM YORAM , MAYEVSKY AVRAHAM
IPC分类号： A61B5/00
CPC分类号： A61B5/0261 , A61B5/0059 , A61B5/0084 , A61B5/14546 , A61B5/1455 , A61B5/412 , A61B5/7214 , A61B2562/0242 , A61B2562/08
摘要： An optical probe, for acquiring measurements of material in a surface, the probe comprising: a probe body; at least one illuminating optical fiber that transmits light to a distal end thereof to illuminate a region of the surface and interact with the material; and at least one receiving optical fiber, positioned to receive light that has been transmitted by the illuminating fiber to the region and has interacted with the material, which received light is used for acquiring the measurements, the receiving fiber thereby being defined as associated with the illuminating fiber; wherein at least one of the fibers has a portion inside the probe body with a bend.
摘要翻译：一种用于获取表面中的材料的测量的光学探针，所述探针包括：探针体; 至少一个照明光纤，其将光透射到其远端以照亮所述表面的区域并与所述材料相互作用; 并且至少一个接收光纤被定位成接收已经被照明光纤传输到该区域并且与接收光的材料相互作用的光已被用于获取测量值，因此接收光纤被定义为与照明纤维; 其中所述纤维中的至少一个在所述探针体内具有弯曲部分。

2. 发明申请

WO2007072424A2 PROBE DESIGN 审中-公开
标题翻译：探索设计
公开(公告)号：WO2007072424A2
公开(公告)日：2007-06-28
申请号：PCT/IB2006/054951
申请日：2006-12-19
申请人： CRITISENSE LTD. , PEWZNER, Eliahu , DEUTSCH, Assaf , BLUM, Yoram , MAYEVSKY, Avraham
发明人： PEWZNER, Eliahu , DEUTSCH, Assaf , BLUM, Yoram , MAYEVSKY, Avraham
IPC分类号： A61B5/026 , A61B5/00
CPC分类号： A61B5/0261 , A61B5/0059 , A61B5/0084 , A61B5/14546 , A61B5/1455 , A61B5/412 , A61B5/7214 , A61B2562/0242 , A61B2562/08
摘要： An optical probe, for acquiring measurements of material in a surface, the probe comprising: a probe body; at least one illuminating optical fiber that transmits light to a distal end thereof to illuminate a region of the surface and interact with the material; and at least one receiving optical fiber, positioned to receive light that has been transmitted by the illuminating fiber to the region and has interacted with the material, which received light is used for acquiring the measurements, the receiving fiber thereby being defined as associated with the illuminating fiber; wherein at least one of the fibers has a portion inside the probe body with a bend.
摘要翻译：一种用于获取表面中的材料的测量的光学探针，所述探针包括：探针体; 至少一个照明光纤，其将光透射到其远端以照亮所述表面的区域并与所述材料相互作用; 并且至少一个接收光纤被定位成接收已经被照明光纤传输到该区域并且与接收光的材料相互作用的光已被用于获取测量值，因此接收光纤被定义为与照明纤维; 其中所述纤维中的至少一个在所述探针体内具有弯曲部分。

3. 发明申请

WO2003026503A1 MULTIPARAMETRIC APPARATUS FOR MONITORING MULTIPLE TISSUE VITALITY PARAMETERS 审中-公开
标题翻译：用于监测多组织健康参数的多功能装置
公开(公告)号：WO2003026503A1
公开(公告)日：2003-04-03
申请号：PCT/IL2001/000900
申请日：2001-09-25
申请人： VITAL MEDICAL LTD. , PEWZNER, Eliahu , MAYEVSKY, Avraham , JARONKIN, Alexander Vasilievitch , DERZY, Igor
发明人： PEWZNER, Eliahu , MAYEVSKY, Avraham , JARONKIN, Alexander Vasilievitch , DERZY, Igor
IPC分类号： A61B5/026
CPC分类号： A61B5/14546 , A61B5/0261 , A61B5/1455 , A61B5/14551
摘要： Apparatus for monitoring a plurality of tissue viability parameters of a substantially identical tissue element, in which a single illumination laser source provides illumination radiation at a wavelength such as to enable monitoring of blood flow rate and NADH or flavoprotein concentration, together with blood volume and also blood oxygenation state. In preferred embodiments, an external cavity laser diode system is used to ensure that the laser operates in single mode or at else in two or three non-competing modes, each mode comprising a relatively narrow bandwidth. A laser stabilisation control system is provided to ensure long term operation of the laser source at the desired conditions.
摘要翻译：用于监测基本上相同的组织元件的多个组织活力参数的装置，其中单个照明激光源提供波长的照射辐射，以便能够监测血液流速和NADH或黄素蛋白浓度以及血液体积，并且还血氧饱和状态。在优选实施例中，使用外腔激光二极管系统来确保激光器以单个模式操作，或者以两个或三个非竞争模式操作，每个模式包括相对窄的带宽。提供激光稳定控制系统以确保激光源在期望条件下的长期操作。

4. 发明申请

WO0224048A2 APPARATUS AND METHOD FOR MONITORING TISSUE VITALITY PARAMETERS 审中-公开
标题翻译：用于监测组织活力参数的装置和方法
公开(公告)号：WO0224048A2
公开(公告)日：2002-03-28
申请号：PCT/IL0100906
申请日：2001-09-25
申请人： VITAL MEDICAL LTD , PEWZNER ELIAHU , MAYEVSKY AVRAHAM
发明人： PEWZNER ELIAHU , MAYEVSKY AVRAHAM
IPC分类号： A61B5/00 , A61B5/026 , A61B
CPC分类号： A61B5/14546 , A61B5/0261 , A61B5/14553 , A61B2562/0242
摘要： Apparatus for monitoring a plurality of tissue viability parameters of a tissue layer element, in which two different illumination sources are used via a common illumination element in contact with the tissue. One illumination source is used for monitoring blood flow rate and optionally flavoprotein concentration, and collection fibers are provided to receive the appropriate radiation from the tissue. The other illuminating radiation is used for monitoring any one of and preferably all of NADH, blood volume and blood oxygenation state of the tissue element, and collection fibers are provided to receive the appropriate radiation from the tissue. In one embodiment, the wavelengths of the two illumination sources are similar, and common collection fibers for the two illuminating radiations are used. In another embodiment, the respective collection fibers are distanced from the illumination point at different distances correlated to the ratio of the first and second illuminating wavelengths.
摘要翻译：用于监测组织层元件的多个组织层存活性参数的设备，其中两个不同的照明源经由与组织接触的共同照明元件被使用。一个照明源用于监测血流速度和任选的黄素蛋白浓度，并且提供收集纤维以从组织接收适当的辐射。其他照射辐射用于监测组织元件的NADH，血容量和血液氧合状态中的任何一个，优选全部，并且提供收集纤维以从组织接收适当的辐射。在一个实施例中，两个照射源的波长相似，并且使用两个照射射线的公共收集光纤。在另一个实施例中，各个收集光纤在与第一和第二照射波长的比率相关的不同距离处与照射点间隔开。

5. 发明申请

WO2003077746A3 DIAGNOSIS OF BODY METABOLIC EMERGENCY STATE 审中-公开
公开(公告)号：WO2003077746A3
公开(公告)日：2003-09-25
申请号：PCT/IL2003/000188
申请日：2003-03-06
申请人： VITAL MEDICAL LTD. , MAYEVSKY, Avraham , PEWZNER, Eliahu , DEUTSCH, Assaf , MANOR, Tamar
发明人： MAYEVSKY, Avraham , PEWZNER, Eliahu , DEUTSCH, Assaf , MANOR, Tamar
IPC分类号： A61B5/00
摘要： AbstractAn apparatus, system and method are provided for diagnosing the degree of body metabolic emergency state. A non-vital organ with respect to the metabolic emergency state is first chosen. One or more tissue viability parameters including at least one of NADH and Flavoprotein (Fp) concentration are monitored in the non-vital organ, whereupon the degree of body metabolic emergency state may be determined based on the monitored tissue viability parameters.

6. 发明申请

WO2003077746A2 APPARATUS AND METHOD FOR MONITORING TISSUE VITALITY PARAMETERS FOR THE DIAGNOSIS OF BODY METABOLIC EMERGENCY STATE 审中-公开
标题翻译：身体代谢状态诊断
公开(公告)号：WO2003077746A2
公开(公告)日：2003-09-25
申请号：PCT/IL2003/000188
申请日：2003-03-06
申请人： VITAL MEDICAL LTD. , MAYEVSKY, Avraham , PEWZNER, Eliahu , DEUTSCH, Assaf , MANOR, Tamar
发明人： MAYEVSKY, Avraham , PEWZNER, Eliahu , DEUTSCH, Assaf , MANOR, Tamar
IPC分类号： A61B5/00
CPC分类号： A61B5/4519 , A61B5/0059 , A61B5/0084 , A61B5/14546 , A61B5/412
摘要： AbstractAn apparatus, system and method are provided for diagnosing the degree of body metabolic emergency state. A non-vital organ with respect to the metabolic emergency state is first chosen. One or more tissue viability parameters including at least one of NADH and Flavoprotein (Fp) concentration are monitored in the non-vital organ, whereupon the degree of body metabolic emergency state may be determined based on the monitored tissue viability parameters.
摘要翻译：摘要提供了一种用于诊断身体代谢紧急状态程度的装置，系统和方法。首先选择关于代谢紧急状态的非重要器官。在非重要器官中监测包括NADH和黄素蛋白（Fp）浓度中的至少一种浓度的一种或多种组织生存力参数，从而可以基于所监测的组织存活力参数来确定身体代谢紧急状态的程度。

7. 发明申请

WO1995032664A1 TISSUE MONITOR 审中-公开
标题翻译：组织监护仪
公开(公告)号：WO1995032664A1
公开(公告)日：1995-12-07
申请号：PCT/US1995006827
申请日：1995-05-26
申请人： FRIEDMAN, Mark, M. , MAYEVSKY, Avraham
发明人： FRIEDMAN, Mark, M.
IPC分类号： A61B01/06
CPC分类号： A61B5/14553
摘要： A single signal-single probe multiparameter analyzer apparatus for monitoring various parameters of the identical volume element of body tissue, which includes an input signal generator, a single signal guide which transmits input signal in, and transmits output signal out, constituting a single signal-single probe, a signal splitter which splits output signal into two or more parts, filters which separate various components of output signal, detectors which measure the different components of the output signal, a computer and an analog-to-digital convertor; and algorithms to evaluate the data.
摘要翻译：一种用于监测身体组织的相同体积元件的各种参数的单个信号 - 单探针多参数分析仪装置，其包括输入信号发生器，将输入信号传输并传输输出信号的单个信号引导器，构成单个信号 - 单个探针，将输出信号分离成两个或更多个部分的信号分离器，分离输出信号的各个分量的滤波器，测量输出信号的不同分量的检测器，计算机和模数转换器; 和算法来评估数据。

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