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1. 发明申请

WO2005011506A3 URETERAL BACKSTOP FILTER AND RETRIEVAL DEVICE 审中-公开
标题翻译： URETERAL BACKSTOP过滤器和检索设备
公开(公告)号：WO2005011506A3
公开(公告)日：2005-07-21
申请号：PCT/US2004024430
申请日：2004-07-29
申请人： COOK UROLOGICAL INC , COOK IRELAND LTD , LITHOTECH MEDICAL LTD , LAVELLE SHAY , ANDREWS MARVIN O , FISCHER FRANK J JR , RYAN WALTER N , DIAMANT VALERY , KHACHIN STEPAN , YASKO NADEZDA , KHACHIN VLADIMIR
发明人： LAVELLE SHAY , ANDREWS MARVIN O , FISCHER FRANK J JR , RYAN WALTER N , DIAMANT VALERY , KHACHIN STEPAN , YASKO NADEZDA , KHACHIN VLADIMIR
IPC分类号： A61B17/22 , A61B17/32 , A61B19/00
CPC分类号： A61B17/221 , A61B17/32056 , A61B90/39 , A61B2017/2212
摘要： A retrieval device for use in renal, biliary, vascular or other systems of a body includes a collapsible basket (15) in a narrow sheath (33). A surgeon advances the device beyond an object (14) to be removed from a body, such as a kidneystone, a gallstone, or a thrombus. The surgeon then retracts the sheath or advances the basket from the sheath. The basket deploys only to one side of the sheath. In some embodiments, the periphery of the basket has a flex point to enable the basket to easily collapse into the sheath. If the sheath is adjacent a body vessel, such as a blood vessel or a ureter (12), the sheath remains adjacent the wall, while the device deploys in such a manner as to seal against the walls of the vessel and block the flow of fragments, emboli, thrombi, or other undesirable objects.
摘要翻译：在身体的肾，胆管，血管或其他系统中使用的检索装置包括在狭窄护套（33）中的可折叠篮（15）。外科医生将装置推进超过物体（14）以从身体移除，例如儿童骨髓，胆结石或血栓。外科医生然后使护套缩回或者将筐从护套推进。篮子仅部署到护套的一侧。在一些实施例中，篮的周边具有弯曲点，以使篮能够容易地折入鞘中。如果鞘与身体容器（例如血管或输尿管（12））相邻，则护套保持邻近壁，同时装置以如下方式展开，以密封容器的壁并阻止碎片，栓塞，血栓或其他不良物品。

2. 发明申请

WO2005013855A3 IMPLANT DELIVERY DEVICE 审中-公开
标题翻译：植入式装置
公开(公告)号：WO2005013855A3
公开(公告)日：2005-04-28
申请号：PCT/US2004021095
申请日：2004-06-30
申请人： COOK UROLOGICAL INC , WARD JOHN H , ANDREWS MARVIN O , FISCHER FRANK J JR
发明人： WARD JOHN H , ANDREWS MARVIN O , FISCHER FRANK J JR
IPC分类号： A61F2/06 , A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A delivery device for placing an implant or prosthesis inside a body is described. The device is useful for placing a variety of stents or implants (11) when used with a cystoscope or other visualization or placement device. An inner sheath (10) is relatively stiff and an outer sheath (12) is relatively pliable or soft compared to the inner sheath. The sheaths are assembled to a connector (15) and a positioner (20) is then inserted through the center of the assembly, the inner sheath. The implant is placed near the distal end of the outer sheath, and the assembled device with the implant is backloaded onto a cystoscope or endoscope for placement. The inner sheath may be used to tailor the stiffness or rigidity of the assembled delivery device.
摘要翻译：描述了用于将植入物或假体放置在体内的递送装置。当与膀胱镜或其他可视化或放置装置一起使用时，该装置可用于放置各种支架或植入物（11）。内护套（10）相对较硬，并且与护套相比，外护套（12）相对柔软或柔软。将护套组装到连接器（15）上，然后将定位器（20）穿过组件的中心，内护套插入。将植入物放置在外护套的远端附近，并将具有植入物的组装装置装载到用于放置的膀胱镜或内窥镜上。内护套可用于定制组装的输送装置的刚度或刚性。

3. 发明申请

WO2004091444A3 IMPLANTABLE MEDICAL DEVICE COMPRISING THERAPEUTIC AGENTS WITH DIFFERENT DIFFUSION RATES 审中-公开
标题翻译：包含具有不同扩张率的治疗药物的可植入医疗装置
公开(公告)号：WO2004091444A3
公开(公告)日：2004-12-16
申请号：PCT/US2004010323
申请日：2004-04-02
申请人： COOK INC , FISCHER FRANK J JR
发明人： FISCHER FRANK J JR
IPC分类号： A61F2/00 , A61F2/82 , A61K51/12 , A61L29/08 , A61L29/16 , A61L31/16 , A61M25/00 , A61M31/00
CPC分类号： A61F2/82 , A61F2250/0035 , A61F2250/0067 , A61K51/1282 , A61L29/085 , A61L29/16 , A61L31/16 , A61L2300/406 , A61L2300/42 , A61L2300/45 , A61M25/0045 , A61M31/002 , C08L83/04
摘要： A medical device comprises first and second members and first and second therapeutic agents. The agents have different diffusion rates through at least one of the members, and are positioned within the medical device based on the diffusion rates. The therapeutic agent having the greater diffusion rate is positioned in the device at a location that is a greater distance from a treatment site than that of the location of the therapeutic agent having the lesser diffusion rate. Methods of making medical devices include placing two or more therapeutic agents within a device based on the diffusion rates of the agents through at least one portion of the device.
摘要翻译：医疗装置包括第一和第二构件以及第一和第二治疗剂。这些试剂通过至少一个构件具有不同的扩散速率，并且基于扩散速率定位在医疗装置内。具有较大扩散速率的治疗剂位于与治疗部位相比处于具有较小扩散速率的治疗剂位置的距离更远的位置。制造医疗装置的方法包括基于药剂通过装置的至少一部分的扩散速率将两种或更多种治疗剂置于装置内。

4. 发明申请

WO0187166A3 Medical device handle 审中-公开
标题翻译：医疗器械手柄
公开(公告)号：WO0187166A3
公开(公告)日：2002-04-25
申请号：PCT/US0116295
申请日：2001-05-18
申请人： COOK UROLOGICAL INC
发明人： HONEY R JOHN D A , ANDREWS MARVIN O , FISCHER FRANK J JR , WARD JOHN H
IPC分类号： A61B17/00 , A61B17/22 , A61B17/28
CPC分类号： A61B17/2909 , A61B17/221 , A61B2017/0046 , A61B2017/00469 , A61B2017/2212 , A61B2017/292
摘要： A replaceable handle (14) for side loading the proximal end of a medical device (12) therein, which is typically inserted with the operating lumen of an endoscope. The replaceable handle can side-load the proximal end of the device into the handle for added manipulation of the distal end such as in removing a stone from the kidney or ureter leading therefrom. An inner housing (52) is rotatable within an outer housing (50) of the handle to secure the medical device in the housing passageway, and is spring biased to then move proximally with respect to the outer housing, moving the inner control rod (22) of the medical device proximally to withdraw the stone basket (16) mostly into the outer cannula (24) and capture the stone (18) for removal from the patient. A push button (70) in the proximal end portion (68) of the inner housing (52) is depressible to permit insertion or withdrawal of the proximal end (34) of the inner control rod (22) of the stone retriever (12) within the inner housing, and is releasable to secure the inner control rod in the handle.

5. 发明申请

WO0004953A2 BRACHYTHERAPY DEVICE INCLUDING AN ANTI-STATIC HANDLE 审中-公开
标题翻译：包括防静电手柄的BRACHYTHERAPY设备
公开(公告)号：WO0004953A2
公开(公告)日：2000-02-03
申请号：PCT/US9915981
申请日：1999-07-15
申请人： COOK UROLOGICAL INC
发明人： ANDREWS MARVIN O , FISCHER FRANK J JR , WARD JOHN W
IPC分类号： A61M36/04 , A61M36/12 , A61N5/10
CPC分类号： A61N5/1027 , A61N2005/1011
摘要： A brachytherapy device (10) for exposing to radioactivity a patient includes an elongate member such as a needle or cannula (12) adapted for introduction into the patient and also includes a stylet (14) slidably receivable in a longitudinal throughbore (16) in the needle (12). The device (10) also includes a portion (64) near either the proximal end (18) of the needle (12) or the distal end (24) of the stylet (14) which provides a local, defined amount of friction between the needle (12) and the stylet (14). The device (10) further includes an anti-static handle (34) connected to the needle (12). The handle (34) has an interior ramp surface (40) in communication with the throughbore (16) of the needle (12), frustoconical in shape and possessing an included apical angle of at least about 16 DEG . The localized friction portion (64) can be a crimp or flange (48) on the stylet (14), or a crimp (44) or deformation (46) in or of the needle (12). The handle (34) is preferably composed of a polycarbonate, acrylic or acetal resin (such resins preferably being carbon-filled, or otherwise electro static dissipative), or a hydroscopic nylon blend. The device (10) is particularly advantageous in that the preferred ramp surface (40) in the handle (34) facilitates the insertion of seeds (26) of radioactive material and inert spacers (28) into the needle (12). The anti-static handle (34) eliminates, for practical purposes, the previously encountered risks of static interference, static cling of the spacers (28) and ignition spark generation. Finally, the localized friction portion (64) provides a controlled and predetermined amount of friction between the needle (12) and the stylet (14), preventing the stylet (14) from falling from the needle (12), while also preventing or reducing the risk of unintended ejection of the radioactive seeds (26) and spacers (28). Such friction is advantageously provided virtually the entire time any portion of the stylet (14) is received in the needle (12).
摘要翻译：用于暴露于放射性的患者的近距离放射治疗装置（10）包括适于引入患者的细长构件，例如针或套管（12），并且还包括可滑动地容纳在纵向通孔（16）中的探针针（12）。装置（10）还包括靠近针头（12）的近端（18）或探针（14）的远端（24）附近的部分（64），该部分提供了在第针（12）和探针（14）。装置（10）还包括连接到针（12）的防静电手柄（34）。手柄（34）具有与针（12）的通孔（16）连通的内部坡道表面（40），其具有截头圆锥形形状并且具有至少约16°的包含顶角。局部摩擦部分（64）可以是探针（14）上的压接或凸缘（48），或针（12）中的压接（44）或变形（46）。手柄（34）优选由聚碳酸酯，丙烯酸或缩醛树脂（优选碳填充或其它电静电耗散的树脂）或吸湿性尼龙混合物组成。装置（10）的特别有利之处在于，手柄（34）中的优选斜面（40）有助于将放射性材料和惰性间隔物（28）的种子（26）插入针（12）中。为了实际目的，防静电手柄（34）消除了先前遇到的静态干扰的风险，间隔件（28）的静态粘附和点火火花产生。最后，局部摩擦部分（64）在针（12）和探针（14）之间提供受控和预定量的摩擦，防止探针（14）从针头（12）掉落，同时也防止或减少放射性种子（26）和间隔物（28）意外喷射的风险。这样的摩擦有利地提供了探针（14）的任何部分被接纳在针（12）中的整个时间。

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