专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2003022790A2 BIPHENYLENE COMPOUNDS 审中-公开
标题翻译：联苯化合物
公开(公告)号：WO2003022790A2
公开(公告)日：2003-03-20
申请号：PCT/EP2002/009627
申请日：2002-08-29
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , HÜGLIN, Dietmar
发明人： WAGNER, Barbara , HÜGLIN, Dietmar
IPC分类号： C07C49/235
CPC分类号： C07D453/02 , A61K8/35 , A61Q17/04 , C07C45/74 , C07C49/683 , C07C49/755 , C07C49/796 , C07C49/813 , C07C67/343 , C07C69/738 , C07C317/44 , C07C2602/08 , C07D239/62
摘要： There are described biphenylene compounds of formula (I) wherein R 1 is a C 1 -C 18 alkyl, C 2 -C 18 alkenyl, C 6 -C 10 aryl or C 6 -C 10 aryl or C 6 -C 10 heteroaryl radical each unsubstituted or mono- or poly-substituted by hydroxy, halogen, C 1 -C 18 alkyl, C 1 -C 18 alkoxy, amino, C 1 -C 5 monoalkylamino or by di-C 1 -C 5 alkylamino; C 5 -C 7 cycloalkyl or C 5 -C 7 cycloalkenyl each unsubstituted or substituted by C 1 -C 5 alkyl; -OR'; or NR'R"; R 2 is a C 1 -C 18 alkyl, C 2 -C 18 alkenyl, C 6 -C 10 aryl or C 6 -C 10 heteroaryl radical each unsubstituted or mono- poly-substituted by hydroxy, hadroxy, C 1 -C 18 alkoxy, amino, C 1 -C 5 monoalkylamino or by di-C 1 -C 5 alkylamino; -OR'; -NR'R"; or R 1 and R 2 together form a 5- to 7- membered monocyclic carbocyclic or heterocyclic ring; R 3 is hydrogen; C 1 -C 6 alkyl or C 1 -C 6 alkoxy; R' and R" are each independently of the other hydrogen; unsubstituted or mono- or poly-hydroxy-, halo-, C 1 -C 18 alkyl-, C 1 -C 18 alkoxy-, amino- or quaternary ammonium groupsubstituted C 1 -C 18 alkyl, C 5 -C 7 cycloalkyl or phenyl; and n is 0 or 1; wherein, when R 2 is OR' or NR'R" and n=1, R 1 is not simultaneously OR'; or NR'R". The compounds according to the invention are suitable especially as sun protection agents in cosmetic, pharmaceutical and veterinary medicine preparations.
摘要翻译：描述了式（I）的亚联苯基化合物，其中R 1是C 1 -C 18烷基 C 2 -C 18链烯基，C 6 -C 10芳基或C 6-12芳基，亚芳基或C 6 -C 10芳杂基各自未被取代或被羟基，卤素，C C 1 -C 18烷基，C 1 -C 18烷氧基，氨基，C 1 -C 18烷基，C 1 -C 18烷氧基， C 5 -C 5单烷基氨基或被C 1 -C 5烷基氨基取代; C 5 -C 7环烷基或C 5 -C 7环烯基各自未被取代或被C 1 -C 6烷基取代， 1 -C <子> 5 烷基; -要么'; 或NR'R“; R 2是C 1 -C 18烷基，C 2 -C 18 - / - 亚烷基每个未被取代或被一个或多个取代基取代的C 1 -C 6烷基，C 6 -C 10芳基或C 6 -C 10芳基，多取代的羟基，甲氧基，C 1 -C 18烷氧基，氨基，C 1 -C 5 - 单烷基氨基或二-C1-C5烷基氨基; -要么'; -NR'R英寸; 或R 1和R 2一起形成5-至7-元单环碳环或杂环; R 3是氢; C 1 -C 6烷基或C 1 -C 6烷氧基; R'和R“ 各自独立于其他氢; 未取代的或单 - 或多 - 羟基 - ，卤素 - ，C 1 -C 18 - 烷基 - ，C 1 -C 18 氨基或季铵基取代的C 1 -C 18烷基，C 5 -C 7烷基，C 5 -C 12芳基，环烷基或苯基; 并且n是0或1; 其中当R 2是OR'或NR'R“时，并且n = 1，R 1不同时是OR'; 或NR'R“。根据本发明的化合物特别适合作为化妆品，药物和兽药制剂中的防晒剂。

2. 发明申请

WO2007014848A2 STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS 审中-公开
标题翻译：身体保健和家居用品的稳定化
公开(公告)号：WO2007014848A2
公开(公告)日：2007-02-08
申请号：PCT/EP2006/064388
申请日：2006-07-19
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , REICH, Oliver
发明人： WAGNER, Barbara , REICH, Oliver
IPC分类号： A61K8/41 , A61K8/49 , A61Q17/04 , C11D3/30 , A61K47/18
CPC分类号： C11D3/30 , A61K8/347 , A61K8/37 , A61K8/375 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/466 , A61K8/4926 , A61K8/496 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q3/02 , A61Q13/00 , A61Q19/005 , C11D3/0084 , C11D3/28 , C11D3/349
摘要： Desribed is the use of specific merocyanine derivatives for protecting body-care and household products from photolytic and oxidative degradation. These compounds perform outstanding UV absorber properties.
摘要翻译：描述的是使用特定的部花青衍生物来保护身体护理和家用产品免受光解和氧化降解。这些化合物具有出色的紫外线吸收剂性能。

3. 发明申请

WO2006003094A2 MEROCYANINE DERIVATIVES 审中-公开
公开(公告)号：WO2006003094A2
公开(公告)日：2006-01-12
申请号：PCT/EP2005/052850
申请日：2005-06-20
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , BIENEWALD, Frank , WOLLEB, Heinz , WALLQUIST, Olof , HERZOG, Bernd , EHLIS, Thomas , HAASE, Jürg
发明人： WAGNER, Barbara , BIENEWALD, Frank , WOLLEB, Heinz , WALLQUIST, Olof , HERZOG, Bernd , EHLIS, Thomas , HAASE, Jürg
IPC分类号： A61K7/42
CPC分类号： A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要： Disclosed is the use of merocyanine derivatives of formula (I), wherein Q is hydrogen; C 1 -C 22 alkyl; -OH; -OR 7 ; -NR 7 R 8 ; or -N=R 9 ; R 1 is hydrogen; C 1 -C 22 alkyl; -OR 7 , -SR 7 ; -NR 7 R 8 ; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 12 aralkyl; C 1 -C 12 heteroalkyl, C 2 -C 11 heteroaralkyl; C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; R 4 is cyano; COR 7 , COOR 7 ; CONR 7 R 8 ; SO 2 (C 6 -C 12 )aryl; C 2 -C 12 alk-1-enyl; C 3 -C 12 cycloalk-1-enyl; C 2 -C 12 alk-1-inyl; C 2 -C 12 heteroalkyl; C 3 -C 5 heterocycloalkyl; C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; R 5 is -COR 7 ; -COOR 7 ; -OR 7 ; -SR 7 , -NHR 7 , -NR 7 R 8 ; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 12 aralkyl; C 1 -C 12 alkylphenyl; C 1 -C 12 alkoxy-C 6 -C 10 aryl; C 1 -C 12 heteroalkyl; C 2 -C 11 heteroaralkyl; C 3 -C 12 cycloheteroalkyl; C 6 -C 10 aryl; C 1 - C 12 alkoxy-C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; R 6 is hydrogen; C 1 -C 22 alkyl; C 1 -C 22 alkoxy; or COR 7 ; R 7 and R 8 independently from each other are hydrogen; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; -(CH 2 ) t COOH; C 7 -C 12 aralkyl; C 1 -C 12 heteroalkyl; C 2 -C 11 heteroaralkyl; C 6 -C 10 aryl; C 1 -C 9 heteroaryl; Si-R 10 R 11 R 12 ; Si(OR 10 )(OR 11 )(OR 12 ); SiR 10 (OR 11 )(OR 12 ); SiR 10 R 11 (OR 12 ); -(CH 2 ) u -O-(CH 2 ) v -SiR 10 R 11 R 12 ; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R 9 is a (C 1 -C 6 )alkylidene radical; R 10 , R 11 , R 12 independently form each other are C 1 -C 22 alkyl; X is a linker; Sil is a silane-, oligosiloxane- or polysiloxane radical; R 1 and R 2 , R 1 and Q, R 1 and R 6 , R 1 and T, R 2 and R 3 , R 2 and R 4 , R 2 and R 6 , R 2 and Q, R 4 and R 6 , R 4 and T, R 6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocyclic rings, and each N atom in a N-heterocyclic ring may be substituted by C 1 -C 22 alkyl; n is a number from 1 to 4; wherein at least one of the radicals R 1 , R 6 or Q is different from hydrogen; if n = 1 T is -COR 5 ; -CN; C 6 -C 10 aryl; -NHR 5 ; or -SO 2 -(C 6 -C 12 )aryl; R 2 and R 3 independently from each other are C 1 -C 22 alkyl; hydroxy-C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl, C 3 -C 12 cycloalkenyl; C 7 -C 12 aralkyl; C 1 -C 12 heteroalkyl; C 3 -C 12 cycloheteroalkyl; C 6 -C 10 aryl; C 1 -C 9 heteroaryl; or a radical of formula (II); p is a number from 5 to 100; q is a number from 1 to 5; s is a number from 0 to 4; if n = 2 R 2 and R 3 are each C 1 -C 5 alkylene; and simultaneously T is defined as for n = 1; or T is a bivalent radical of formula -NR 7 -V-NR 7 -, wherin V is phenylene; or C 1 -C 5 alkylene; R 7 is hydrogen; or C 1 -C 5 alkyl; and R 2 and R 3 simultaneously are defined as for n = 1; if n = 3 one of R 2 , R 3 or T is a trivalent radical; if n = 4 one of R 2 , R 3 or T is a tetravalent radical; for protecting of human hair and skin against the damaging effect of UV radiation.

4. 发明申请

WO2008012304A1 USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF 审中-公开
标题翻译：用于保护人类和动物皮肤和毛发的氨基茚并苯并噻唑衍生物从紫外线辐射及其化妆品组合物的有害作用中的应用
公开(公告)号：WO2008012304A1
公开(公告)日：2008-01-31
申请号：PCT/EP2007/057614
申请日：2007-07-24
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara
发明人： WAGNER, Barbara
IPC分类号： A61K8/49 , A61Q5/00 , A61Q17/04
CPC分类号： A61K8/496 , A61Q5/00 , A61Q17/04 , A61Q19/08
摘要： Disclosed are-(2'-Hydroxy-4'-aminophenyl)benzotriazole derivatives of formula (1), wherein R 1 and R 4 independently of each other are hydrogen; C 1 -C 28 alkyl; C 1 -C 28 alkoxy; C 2 -C 28 al- kenyl; C 2 -C 28 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 28 aralkyl; C 1 -C 20 hetero- alkyl; C 3 -C 12 cycloheteroalkyl; or C 5 -C 16 heteroaralkyl; and wherein C 1 -C 28 alkyl, C 1 -C 28 al- koxy, C 2 -C 28 alkenyl and C 2 -C 28 alkinyl are unsubstituted or may be substituted by at least one C 1 -C 5 alkyl, C 1 -C 5 alkoxy or hydroxy; R 2 and R 3 independently of each other are hydrogen; C 1 -C 28 alkyl; C 2 -C 28 alkenyl; C 2 -C 22 alki- nyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 28 aralkyl; C 1 -C 20 heteroalkyl; C 3 -C 12 cyclo- heteroalkyl; C 5 -C 16 heteroaralkyl; and wherein C 1 -C 28 alkyl, C 1 -C 28 alkoxy, C 2 -C 28 alkenyl and C 2 -C 28 alkinyl are unsubstituted or may be substituted by at least one C 1 -C 5 alkyl, C 1 - C 5 alkoxy or hydroxy; or CO-R 5 ; or R 2 and R 3 together together with the linking nitrogen form a 5- to 7-membered, monocyclic, carbocyclic or heterocyclic ring; R 5 is C 1 -C 28 alkyl; C 2 -C 28 alkenyl; C 2 -C 28 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 20 aralkyl; C 1 -C 20 heteroalkyl; C 3 -C 12 cycloheteroalkyl; C 1 -C 5 alkoxycarbonyl-C 1 - C 5 alkyl; or C 5 -C 16 heteroaralkyl; for protecting human and animal hair and skin from harmful effects of UV radiation.
摘要翻译：公开的式（1）的（2'-羟基-4'-氨基苯基）苯并三唑衍生物，其中R 1和R 4彼此独立地是氢; ç_{1 -C _{28 烷基; ç_{1 -C _{28 烷氧基; C 2 -C 28亚烯基; ç_{2 -C _{28 炔基; ç_{3 -C _{12 环烷基; ç_{3 -C _{12 环烯基; C 7 -C 28芳烷基; C 1 -C 20 - 杂 - 烷基; ç_{3 -C _{12 环; 或C 5 -C 16 - 杂芳烷基; 并且其中C 1 -C 28烷基，C 1 -C 28烷氧基，C 1 -C 12烷基，C 1 -C 12烷基， C 2 -C 12烷基和C 2 -C 28炔基是未取代的或可被至少一个C _{1 -C _{28 烷基; C 2 -C 28链烯基; C 2 -C 22烷基; ç_{3 -C _{12 环烷基; ç_{3 -C _{12 环烯基; C 7 -C 28芳烷基; C 1 -C 20杂烷基; C 3 -C 12环杂烷基; ç_{5 -C _{16 杂芳烷基; 并且其中C 1 -C 28烷基，C 1 -C 28烷氧基，C 2 -C 12烷基， C 1 -C 28烷基和C 2 -C 28炔基是未取代的或可以被至少一个C 1〜 C 1 -C 5烷基，C 1 -C 5烷氧基或羟基; C 1 -C 5烷基，C 1 -C 5烷基，C 1 -C 5烷基，或CO-R 5; 或R 2和R 3 3与连接氮一起形成5-至7-元单环，碳环或杂环; R 5是C 1 -C 28烷基; ç_{2 -C _{28 烯基; ç_{2 -C _{28 炔基; ç_{3 -C _{12 环烷基; ç_{3 -C _{12 环烯基; ç_{7 -C _{20 芳烷基; C 1 -C 20杂烷基; C 3 -C 12环杂烷基; C 1 -C 5烷氧基羰基-C 1 -C 5烷基; C 1 -C 5烷基; 或C 5 -C 16 - 杂芳烷基; 用于保护人体和动物毛发和皮肤免受紫外线辐射的有害影响。}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}

5. 发明申请

WO2007071582A1 MEROCYANINE DERIVATIVES 审中-公开
标题翻译：月桂酰胺衍生物
公开(公告)号：WO2007071582A1
公开(公告)日：2007-06-28
申请号：PCT/EP2006/069516
申请日：2006-12-11
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , WALTHER, Astrid , HERZOG, Bernd
发明人： WAGNER, Barbara , WALTHER, Astrid , HERZOG, Bernd
IPC分类号： C07C255/31 , C07C317/32 , A61K8/41 , A61Q17/04
CPC分类号： C07C317/44 , C07C255/31 , C07C2601/16
摘要： Disclosed are merocyanine derivatives of formula (1), wherein R 1 and R 2 independently from each other are branched C 4 -C 22 alkyl; or branched C 4 -C 12 alkenyl; R 3 and R 4 independently from each other are cyano; COR 7 , COOR 7 ; CONR 7 R 8 ; SO 2 (C 6 - C 12 )aryl; C 2 -C 12 alk-1-enyl; C 3 -C 12 cycloalk-1-enyl; C 2 -C 12 alk-1-inyl; C 2 -C 12 heteroalkyl; C 3 - C 5 heterocycloalkyl; C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; wherein at least one of R 3 and R 4 is cyano; R 5 and R 6 independently from each other are hydrogen; C 1 -C 6 alkyl; C 5 -C 8 cycloalkyl which may be substituted by one or more than one C 1 -C 4 alkyl; and R 7 and R 8 independently from each other are hydrogen; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 - C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; -(CH 2 ) t COOH; C 7 -C 12 aralkyl; C 1 - C 12 heteroalkyl; C 2 -C 11 heteroaralkyl; C 6 -C 10 aryl; C 1 -C 9 heteroaryl. The compounds are useful as UV absorbers for protecting human hair and skin against the damaging effect of UV radiation.
摘要翻译：公开了式（1）的部花青衍生物，其中R 1和R 2彼此独立地为支链C 1-4 - 22 烷基; 或支化C 4 -C 12链烯基; R 3和R 4彼此独立地是氰基; COR 7 7，COOR 7; CONR _{7 - [R _{8 ; SO 2（C 6 -C 12）芳基; ç_{2 -C _{12 烷-1-烯基; ç_{3 -C _{12 环烷-1-烯基; ç_{2 -C _{12 烷-1-炔; ç_{2 -C _{12 杂烷基; C 3 -C 5杂环烷基; ç_{6 -C _{10 芳基; 或C 1 -C 9 - 杂芳基; 其中R 3和R 4中的至少一个是氰基; R 5和R 6彼此独立地是氢; ç_{1 -C _{6 烷基; 可以被一个或多于一个C 1 -C 4 - 亚烷基取代的C 5 -C 8环烷基 ; 和R 7和R 8彼此独立地是氢; ç_{1 -C _{22 烷基; ç_{2 -C _{12 烯基; C 2 -C 12炔基; ç_{3 -C _{12 环烷基; ç_{3 -C _{12 环烯基; - （CH _{2 ）_{吨 COOH; ç_{7 -C _{12 芳烷基; C 1 -C 12 - 杂烷基; ç_{2 -C _{11 杂芳烷基; ç_{6 -C _{10 芳基; ç_{1 -C _{9 杂芳基。这些化合物可用作紫外线吸收剂，用于保护人体毛发和皮肤免受紫外线辐射的破坏作用。}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}

6. 发明申请

WO2004006878A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE 审中-公开
标题翻译：用于化妆品使用的MEROCANANINE衍生物
公开(公告)号：WO2004006878A1
公开(公告)日：2004-01-22
申请号：PCT/EP2003/006955
申请日：2003-07-01
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , EHLIS, Thomas , EICHIN, Kai
发明人： WAGNER, Barbara , EHLIS, Thomas , EICHIN, Kai
IPC分类号： A61K7/42
CPC分类号： C07D239/54 , A61K8/4906 , A61Q17/04 , C07C255/30 , C07C255/31 , C07C2601/16 , C07D207/20 , C07D231/36 , C07D263/14 , C07D277/10 , C07D295/145 , C07D295/155 , C07D319/06
摘要： The use is described of merocyanine derivatives of formula (1), wherein R 1 and R 2 are each independently of the other hydrogen; C 1 -C 22 alkyl; cyclo-C 3 C 8 alkyl; or unsubstituted or C 1 -C 5 alkyl- or C 1 -C 5 alkoxy-substituted C 6 -C 20 aryl; orl; or R 1 and R 2 together with the nitrogen atom linking them form a -(CH 2 ) m - ring which is uninterrupted or. interrupted by -O- or by -NH-; R 3 is a cyano group; -COOR 5 ; -CONHR 5 ; -COR 5 ; or -SO 2 R 5 ; R 4 is a cyano group; -COOR 6 ; -CONHR 6 ; -COR 6 ; or -SO 2 R 6 ; R 5 and R 6 are each independently of the other C 1 -C 22 alkyl; or unsubstituted or C 1 -C 5 alkyl substituted C 6 -C 20 aryl; or R 3 and R 4 together or R 5 and R 6 together form a 5- to 7-membered, monocyclic, carbocyclic or heterocyclic ring; Z 1 , and Z 2 are each independently of the other a -(CH 2 ),- group which is uninterrupted or interrupted by -O-, -S-, or by -NR 7 -, and/or is unsubstituted or substituted by C, 1 -C 5 alkyl; R 7 is C 1 C 5 alkyl; I is from 1 to 4; m is from 1 to 7; n is from 1 to 4; when n = 2, R 1 , R 5 or R 6 is a bivalent alkyl group; or R 1 , and R 2 together with the 2 nitrogen atoms linking them form a -(CH 2 ) m - ring; when n = 3, R 1 , R 5 or R 6 is a trivalent alkyl group; when n = 4, R 1 , R 5 or R 6 is a tetravalent alkyl group; and R 1 , and R 2 in formula (1) are not simultaneously hydrogen, in protecting human and animal hair and skin from UV radiation.
摘要翻译：描述了式（1）的部花青衍生物，其中R 1和R 2各自独立地为氢; C1-C22烷基; 环C3C8alkyl; 或未取代的或C 1 -C 5烷基 - 或C 1 -C 5烷氧基取代的C 6 -C 20芳基; ORL; 或R 1和R 2与连接它们的氮原子一起形成不间断的 - （CH 2）m - 环。被-O-或-NH-中断; R3是氰基; -COOR5; -CONHR5; -COR5; 或-SO 2 R 5; R4是氰基; -COOR6; -CONHR6; -COR 6; 或-SO 2 R 6; R 5和R 6各自独立地为C 1 -C 22烷基; 或未取代的或C 1 -C 5烷基取代的C 6 -C 20芳基; 或R 3和R 4一起或R 5和R 6一起形成5-至7-元单环，碳环或杂环; Z 1和Z 2各自独立地为不间断或被-O - ， - S-或-NR 7 - 间隔的另一个 - （CH 2） - 基，和/或未取代或被C 1〜 C 5烷基; R7是C1C5烷基; 我是从1到4; m为1〜7; n为1至4; 当n = 2时，R 1，R 5或R 6为二价烷基; 或R 1和R 2与连接它们的2个氮原子一起形成 - （CH 2）m - 环; 当n = 3时，R 1，R 5或R 6为三价烷基; 当n = 4时，R 1，R 5或R 6为四价烷基; 式（1）中的R 1和R 2不同时为氢，以保护人和动物的头发和皮肤免受UV辐射。

7. 发明申请

WO2003016289A1 TRIAZINE DERIVATIVES AND THEIR USE AS SUNSCREENS 审中-公开
标题翻译： TRIAZINE衍生物及其作为SUNSCREENS的用途
公开(公告)号：WO2003016289A1
公开(公告)日：2003-02-27
申请号：PCT/EP2002/008888
申请日：2002-08-08
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara
发明人： WAGNER, Barbara
IPC分类号： C07D251/18
CPC分类号： A61Q17/04 , A61K8/4966 , C07D251/18 , C07D251/54 , C07D251/70 , C07D405/14
摘要： There are described triazine derivatives of formula (1), wherein R 1 is an unsubstituted or mono- or poly-hydroxy-, C 1 -C 18 alkyl-, C 1 -C 18 alkoxy-, amino-, C 1 -C 5 monoalkylamino- or di-C 1 -C 5 alkylamino-substituted C 1 -C 18 alkyl, C 2 -C 18 alkenyl, C 6 -C 10 aryl or C 6 -C 10 heteroaryl radical; unsubstituted or C 1 -C 5 alkyl-substituted C 5 -C 7 cycloalkyl or C 5 -C 7 cycloalkenyl; -OR'; or -NR'R"; R 2 is hydrogen; an unsubstituted or mono- or poly-hydroxy-, C 1 -C 18 alkoxy-, cyano-, amino, C 1 -C 5 monoalkylamino- or di-C 1 -C 5 alkylamino-substituted C 1 -C 18 alkyl, C 2 -C 18 alkenyl; C 6 -C 10 aryl or C 6 -C 10 heteroaryl radical; -OR'; or -NR'R"; or R 1 and R 2 together form a 5- to 7-membered carbocyclic or heterocyclic ring; A is C 1 -C 5 alkyl; an unsubstituted or hydroxy-, C 1 -C 18 alkyl- or C 1 -C 18 alkoxy-substituted C 6 -C 10 aryl or heteroaryl radical; or a radical of formula (1a); R' and R" are each independently of the other hydrogen; unsubstituted or mono- or poly-hydroxy-, halo-, C 1 -C 18 alkyl-, C 1 -C 18 alkoxy-, amino- or quaternary ammonium group-substituted C 1 -C 18 alkyl, C 5 -C 7 cycloalkyl or phenyl; R 3 is hydrogen; or C 1 -C 6 alkyl; and n is 0 or 1. The compounds according to the invention are suitable especially as sun protective agents in cosmetic, pharmaceutical and veterinary medicine preparations.
摘要翻译：描述了式（1）的三嗪衍生物，其中R 1是未取代的或单 - 或多羟基 - ，C 1 -C 18烷基 - ，C 1 -C 18烷氧基 - ，氨基 - ，C 1 -C 5单烷基氨基 - 或二-C C5烷基氨基取代的C1-C18烷基，C2-C18烯基，C6-C10芳基或C6-C10杂芳基; 未取代的或C 1 -C 5烷基取代的C 5 -C 7环烷基或C 5 -C 7环烯基; -要么'; 或-NR'R“; R 2是氢;未取代的或单 - 或多羟基 - ，C 1 -C 18烷氧基 - ，氰基 - ，氨基，C 1 -C 5单烷基氨基或二-C 1 -C 5烷基氨基取代的C 1 -C 18 烷基，C 2 -C 18烯基; C 6 -C 10芳基或C 6 -C 10杂芳基; -OR';或-NR'R“; 或R 1和R 2一起形成5-至7-元的碳环或杂环; A是C 1 -C 5烷基; 未取代或羟基，C 1 -C 18烷基或C 1 -C 18烷氧基取代的C 6 -C 10芳基或杂芳基; 或式（1a）的基团; R'和R“各自独立地为氢;未取代的或单羟基或多羟基，卤代，C 1 -C 18烷基 - ，C 1 -C 18烷氧基 - ，氨基或季铵基取代的C 1 -C 18烷基 C 5 -C 7环烷基或苯基; R 3为氢;或C 1 -C 6烷基; n为0或1.本发明化合物特别适用于化妆品，药物和兽药制剂中的防晒剂。

8. 发明申请

WO2005058269A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE 审中-公开
标题翻译：用于化妆品使用的MEROCANANINE衍生物
公开(公告)号：WO2005058269A1
公开(公告)日：2005-06-30
申请号：PCT/EP2004/053327
申请日：2004-12-08
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , EHLIS, Thomas , MÜLLER, Stefan
发明人： WAGNER, Barbara , EHLIS, Thomas , MÜLLER, Stefan
IPC分类号： A61K7/42
CPC分类号： C07D295/116 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/494 , A61K8/81 , A61Q17/00 , A61Q17/02 , C07C225/20 , C07C229/46 , C07C255/31 , C07C317/48 , C07C2601/14 , C07C2601/16 , C07D295/155
摘要： Described are merocyanine derivatives of formula (1a) or (1b) wherein n and o are integers from 2 to 4 and aminocyclohexenone intermediates. They are used in protecting human and animal hair and skin from UV radiation.
摘要翻译：描述的是式（1a）或（1b）的部花青衍生物，其中n和o是2-4的整数和氨基环己烯酮中间体。它们用于保护人体和动物的毛发和皮肤免受紫外线辐射。

9. 发明申请

WO2005012235A1 3-ARYL-2-CYANO-3-HYDROXY-ACRYLIC ACID DERIVATIVES 审中-公开
标题翻译： 3-亚甲基-2-氰基-3-羟基 - 丙烯酸衍生物
公开(公告)号：WO2005012235A1
公开(公告)日：2005-02-10
申请号：PCT/EP2004/051533
申请日：2004-07-19
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , RELE, Dinesh Narendra , BHATTI, Harjinder Singh , HÖLZL, Werner , MARQUAIS-BIENEWALD, Sophie , MATHIAS, Errol Vincent , PREUSS, Andrea , WAGNER, Barbara
发明人： RELE, Dinesh Narendra , BHATTI, Harjinder Singh , HÖLZL, Werner , MARQUAIS-BIENEWALD, Sophie , MATHIAS, Errol Vincent , PREUSS, Andrea , WAGNER, Barbara
IPC分类号： C07C255/41
CPC分类号： C07C255/41 , A61K8/40 , A61L2/16 , A61Q15/00 , C11D3/26 , C11D7/32 , D06M13/1845 , Y10T442/2525
摘要： Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R 1 is hydrogen, C 1 -C 20 alkyl; C 1 -C 20 alkoxy; CF 3 ; C 6 -C 10 aryl; or a radical of formula (1 a) and R 2 is hydrogen; or C 1 -C 20 alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.
摘要翻译：公开了式（1a）（1b）或（1c）的3-芳基-2-氰基-3-羟基 - 丙烯酸衍生物，其中R 1是氢，C 1 -C 20烷基; C1-C20alkoxy; CF3; C6-C10芳基; 或式（1a）和R2的基团是氢; 或C 1 -C 20烷基。这些化合物用作治疗表面的抗微生物活性物质。

10. 发明申请

WO2003086341A3 AMINOPHENYLBENZOTHIAZOLE COMPOUNDS 审中-公开
公开(公告)号：WO2003086341A3
公开(公告)日：2003-10-23
申请号：PCT/EP2003/003870
申请日：2003-04-14
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , EHLIS, Thomas , MONGIAT, Sébastien , EICHIN, Kai
发明人： WAGNER, Barbara , EHLIS, Thomas , MONGIAT, Sébastien , EICHIN, Kai
IPC分类号： C07D277/66
摘要： The Use, as a UV filter, of a compound of formula (I), wherein R 1 and R 2 are each independently of the other hydrogen; unsubstituted or halo-, amino-, mono- or di-C 1 -C 5 alkylamino-, cyano- or C 1 -C 5 alkoxy-substituted C 1 -C 22 alkyl, C 5 -C 10 cycloalkyl, carboxy-C 1 -C 22 alkyl, carboxy-C 6 -C 10 aryl, C 6 -C 10 aryl, C 6 -C 10 aryl-C 1 -C 5 alkyl; carbamoyl; or sulfamoyl; or R 1 and R 2 , together with the nitrogen atom linking them, form a 5- to 7-membered heterocyclic radical; and R 3 is hydrogen; or C 1 -C 22 alkyl; and R 4 is hydrogen; hydroxy; C 1 -C 22 alkyl; or C 1 -C 22 alkoxy; is described. The compounds of formula (I) are suitable especially as UV filters in cosmetic preparations.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式