专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2002058698A3 MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS 审中-公开
公开(公告)号：WO2002058698A3
公开(公告)日：2002-08-01
申请号：PCT/US2002/001789
申请日：2002-01-22
申请人： CHUGAI SEIYAKU KABUSHIKI KAISHA , ARRHENIUS, Thomas , CHEN, Mi , CHENG, Jie Fei , HUANG, Yujin , NADZAN, Alex , PENULIAR, Richard , WALLACE, David , ZHANG, Lin
发明人： ARRHENIUS, Thomas , CHEN, Mi , CHENG, Jie Fei , HUANG, Yujin , NADZAN, Alex , PENULIAR, Richard , WALLACE, David , ZHANG, Lin
IPC分类号： A61K31/42
摘要： The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.

2. 发明申请

WO2002058698A2 MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS 审中-公开
标题翻译：马来酸 - 癸酸脱羧酶抑制剂作为代谢调节剂有用
公开(公告)号：WO2002058698A2
公开(公告)日：2002-08-01
申请号：PCT/US2002/001789
申请日：2002-01-26
申请人： CHUGAI SEIYAKU KABUSHIKI KAISHA , ARRHENIUS, Thomas , CHEN, Mi , CHENG, Jie Fei , HUANG, Yujin , NADZAN, Alex , PENULIAR, Richard , WALLACE, David , ZHANG, Lin
发明人： ARRHENIUS, Thomas , CHEN, Mi , CHENG, Jie Fei , HUANG, Yujin , NADZAN, Alex , PENULIAR, Richard , WALLACE, David , ZHANG, Lin
IPC分类号： A61K31/42
CPC分类号： C07D233/64 , A61K31/16 , A61K31/41 , A61K31/415 , A61K31/4164 , A61K31/42 , A61K31/44 , A61K31/5375 , C07C33/48 , C07C215/24 , C07C233/22 , C07C307/10 , C07C323/14 , C07D239/42 , C07D261/04 , C07D261/08 , C07D277/46 , C07D277/48 , C07D277/52 , C07D285/135 , C07D307/46 , C07D401/12 , C07D413/06 , C07D413/12 , C07D417/12 , C07D417/14 , C07D487/08 , C07F9/6539
摘要： The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.
摘要翻译：本发明涉及新型化合物（I），其前药和药学上可接受的盐以及含有这样的化合物的药物组合物，其可用于治疗某些代谢疾病和通过抑制酶丙二酰辅酶A脱羧酶（丙二酰 - CoA脱羧酶，MCD）。特别地，本发明涉及通过抑制丙二酰辅酶A脱羧酶来预防，治疗和治疗心血管疾病，糖尿病，酸中毒，癌症和肥胖的化合物和组合物和方法。

3. 发明申请

WO2002058690A2 METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS 审中-公开
标题翻译：使用MALONYL-COA DECARBOX YLASE INHIBITORS治疗疾病的方法
公开(公告)号：WO2002058690A2
公开(公告)日：2002-08-01
申请号：PCT/US2002/001814
申请日：2002-01-22
申请人： CHUGAI SEIYAKU KABUSHIKI KAISHA , ARRHENIUS, Thomas , CHEN, Mi , CHENG, Jie Fei , HARAMURA, Masayuki , HUANG, Yujin , NADZAN, Alex , TITH, Sovouthy , WALLACE, David , ZHANG, Lin , BROWN, Steve , HARMON, Charles
发明人： ARRHENIUS, Thomas , CHEN, Mi , CHENG, Jie Fei , HARAMURA, Masayuki , HUANG, Yujin , NADZAN, Alex , TITH, Sovouthy , WALLACE, David , ZHANG, Lin , BROWN, Steve , HARMON, Charles
IPC分类号： A61K31/16
CPC分类号： C07D231/06 , A61K31/16 , A61K31/165 , A61K31/17 , A61K31/175 , A61K31/18 , A61K31/197 , A61K31/221 , A61K31/275 , A61K31/40 , A61K31/41 , A61K31/415 , A61K31/416 , A61K31/4164 , A61K31/4178 , A61K31/4188 , A61K31/4196 , A61K31/42 , A61K31/44 , A61K31/4402 , A61K31/4409 , A61K31/4439 , A61K31/451 , A61K31/5375 , A61K31/5377 , C07C33/46 , C07C33/48 , C07C215/24 , C07C233/22 , C07C257/22 , C07C279/18 , C07C307/10 , C07C323/14 , C07C335/18 , C07D231/14 , C07D233/64 , C07D233/90 , C07D239/42 , C07D261/04 , C07D261/08 , C07D261/14 , C07D261/18 , C07D277/46 , C07D277/48 , C07D277/52 , C07D285/135 , C07D295/13 , C07D295/194 , C07D295/21 , C07D295/215 , C07D295/32 , C07D307/46 , C07D307/52 , C07D401/12 , C07D413/06 , C07D413/12 , C07D417/12 , C07D417/14 , C07D487/08 , C07F9/247 , C07F9/4021 , C07F9/6539
摘要： The present invention relates to methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD) by the administration of a composition containing as an active ingredient a compound according to Formula I. In particular, the invention relates to methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the administration of a compound which inhibits malonyl-coenzyme A decarboxylase activity. The present invention also includes within its scope the novel process for the preparation of certain compounds.
摘要翻译：本发明涉及通过施用含有作为活性成分的化合物的组合物来抑制由丙二酰辅酶A脱羧酶（丙二酰辅酶A脱羧酶，MCD）抑制的某些疾病的预防，治疗和治疗方法特别地，本发明涉及通过施用抑制丙二酰辅酶A脱羧酶活性的化合物来预防，治疗和治疗心血管疾病，糖尿病，酸中毒，癌症和肥胖症的方法。本发明在其范围内还包括制备某些化合物的新方法。

4. 发明申请

WO2002076438A3 FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS 审中-公开
公开(公告)号：WO2002076438A3
公开(公告)日：2002-10-03
申请号：PCT/US2002/008862
申请日：2002-03-21
申请人： CHUGAI SEIYAKU KABUSHIKI KAISHA , ARRHENIUS, Thomas , HUANG, Yujin , ZHANG, Lin , SERAFIMOV, Rossy , NADZAN, Alex , SPINELLA, Dominic
发明人： ARRHENIUS, Thomas , HUANG, Yujin , ZHANG, Lin , SERAFIMOV, Rossy , NADZAN, Alex , SPINELLA, Dominic
IPC分类号： A61K31/00
摘要： This invention is a method of treatment and prophylaxis of diseases regulatable by angiogenesis, including novel FLT-1 ligands and pharmaceutical compositions containing them, useful in the methods for the treatment and prophylaxis of these diseases, as well as intermediates and processes useful for the preparation of the compounds of the invention as claimed.

5. 发明申请

WO2010051233A3 ADJUSTABLE GAS DISTRIBUTION APPARATUS 审中-公开
公开(公告)号：WO2010051233A3
公开(公告)日：2010-05-06
申请号：PCT/US2009/061893
申请日：2009-10-23
申请人： APPLIED MATERIALS, INC. , ZHANG, Lin , TSUEI, Lun , TSO, Alan , CHO, Tom K. , SHIEH, Brian Sy-Yuan
发明人： ZHANG, Lin , TSUEI, Lun , TSO, Alan , CHO, Tom K. , SHIEH, Brian Sy-Yuan
IPC分类号： H01L21/205 , H05H1/34
摘要： Embodiments of the present invention generally provide apparatus and methods for altering the contour of a gas distribution plate within a process chamber without breaking vacuum conditions within the chamber. In one embodiment, a central support device adjusted to vary the height of a central region of a gas distribution plate with respect to the periphery of the gas distribution plate. In another embodiment, a plurality of central support devices is adjusted to vary the height of a central region of a gas distribution plate with respect to the periphery of the plate. In yet another embodiment, a plurality of central support devices and a plurality of mid-range support devices are adjusted to vary the height of certain regions of the gas distribution plate with respect to other regions of the gas distribution plate. In one embodiment, the contour of the gas distribution plate is altered based on changes detected within the process chamber.

6. 发明申请

WO2005004836A2 SAQUINAVIR MESYLATE ORAL DOSAGE FORM 审中-公开
标题翻译： SAQUINAVIR MESYLATE口服剂型
公开(公告)号：WO2005004836A2
公开(公告)日：2005-01-20
申请号：PCT/EP2004/007309
申请日：2004-07-05
申请人： F.HOFFMANN-LA ROCHE AG , ALBANO, Antonio, A. , INFELD, Martin, Howard , PHUAPRADIT, Wantanee , SHAH, Navnit-Hargovindas , ZHANG, Lin
发明人： ALBANO, Antonio, A. , INFELD, Martin, Howard , PHUAPRADIT, Wantanee , SHAH, Navnit-Hargovindas , ZHANG, Lin
IPC分类号： A61K9/00
CPC分类号： A61K31/551 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/2054
摘要： A solid unit oral pharmaceutical dosage form of saquinavir mesylate is provided comprising micronized saquinavir mesylate in an amount of from 250 mg to 800 mg calculated as free base, and a pharmaceutically acceptable binder, disintegrant, and water soluble carrier. A solid unit dosage form of saquinavir mesylate is provided comprising from 60% to 80% micronized saquinavir mesylate based on the mesylate salt, 4% to 8% water soluble binder, a disintegrant and a carrier, wherein each percentage is of the kernel weight.
摘要翻译：提供了甲磺酸沙奎那韦的固体单位口服药物剂型，其包含以游离碱计250mg至800mg量的微粉化甲基沙奎那韦以及药学上可接受的粘合剂，崩解剂和水溶性载体。提供了甲磺酸沙奎那韦的固体单位剂型，其包含基于甲磺酸盐的60％至80％微粉化的甲基磺草沙芬那韦，4％至8％的水溶性粘合剂，崩解剂和载体，其中每个百分比为粒重。

7. 发明申请

WO2011011301A2 A MIXED SILICON PHASE FILM FOR HIGH EFFICIENCY THIN FILM SILICON SOLAR CELLS 审中-公开
标题翻译：用于高效薄膜硅太阳电池的混合硅相薄膜
公开(公告)号：WO2011011301A2
公开(公告)日：2011-01-27
申请号：PCT/US2010/042392
申请日：2010-07-19
申请人： APPLIED MATERIALS, INC. , YANG, Fan , ZHANG, Lin , ZHENG, Yi , SCHMITT, Francimar , YUAN, Zheng
发明人： YANG, Fan , ZHANG, Lin , ZHENG, Yi , SCHMITT, Francimar , YUAN, Zheng
IPC分类号： H01L31/075
CPC分类号： H01L31/03685 , H01L31/03762 , H01L31/075 , H01L31/076 , H01L31/1824 , H01L31/202 , Y02E10/545 , Y02E10/548 , Y02P70/521
摘要： A method and apparatus for forming solar cells is provided. In one embodiment, a photovoltaic device includes a first p-i-n junction cell formed on a substrate, wherein the p-i-n junction cell comprises a p-type silicon containing layer, an intrinsic type silicon containing layer formed over the p-type silicon containing layer, and a n-type silicon containing layer formed over the intrinsic type silicon containing layer, wherein the intrinsic type silicon containing layer comprises a first pair of microcrystalline layer and amorphous silicon layer.
摘要翻译：提供了一种用于形成太阳能电池的方法和设备。在一个实施例中，光伏器件包括形成在衬底上的第一pin结电池，其中pin结电池包括p型含硅层，形成在p型含硅层上的本征型含硅层和在本征型含硅层上形成的n型含硅层，其中本征型含硅层包含第一对微晶层和非晶硅层。

8. 发明申请

WO2008094575A3 1-H-PYRAZOLO(3,4B)PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES 审中-公开
公开(公告)号：WO2008094575A3
公开(公告)日：2008-08-07
申请号：PCT/US2008/001195
申请日：2008-01-30
申请人： BIOGEN IDEC MA INC. , KASIBHATLA, Srinivas, Rao , HONG, Kevin , ZHANG, Lin , BOEHM, Marcus, F. , FAN, Junhua , LE BRAZIDEC, Jean-yves
发明人： KASIBHATLA, Srinivas, Rao , HONG, Kevin , ZHANG, Lin , BOEHM, Marcus, F. , FAN, Junhua , LE BRAZIDEC, Jean-yves
IPC分类号： C07D487/04 , A61K31/505 , A61P35/00
摘要： The invention relates to compounds of Formula (I), a polymorph, an enantiomer a stereoisomer, a solvate, an N-oxide, or a pharmaceutically acceptable salt thereof; which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.

9. 发明申请

WO2008007062A2 A TORSION SENSOR 审中-公开
标题翻译： TORSION传感器
公开(公告)号：WO2008007062A2
公开(公告)日：2008-01-17
申请号：PCT/GB2007/002547
申请日：2007-07-09
申请人： ASTON UNIVERSITY , BENNION, Ian , ZHOU, Kaiming , CHEN, Xianfeng , ZHANG, Lin
发明人： BENNION, Ian , ZHOU, Kaiming , CHEN, Xianfeng , ZHANG, Lin
IPC分类号： G01L1/00
CPC分类号： G01M11/088 , G01L3/12
摘要： A torsion sensor (1) using an optical waveguide (2) in optical communication with a diffraction grating (3), preferably a tilted grating, and most preferably a tilted Bragg grating, which provides the optical waveguide and grating with a torsion-dependent collective optical transmission spectrum. Changes in the collective optical transmission spectrum of the waveguide and grating, induced by changes in the amount of torsion applied to the waveguide, may be detected (12) by detecting a corresponding change in the intensity of optical radiation transmitted through the grating from a controlled optical source (5). The degree of change in the collective optical transmission spectrum is dependent upon the degree of torsion (twist) applied to the optical waveguide. Measuring the magnitude and/or sense ( i.e. increase/decrease) in the intensity of optical radiation transmitted through the grating from an optical source enables torsion to be sensed.
摘要翻译：使用与衍射光栅（3）光学连通的光波导（2）的扭转传感器（1），优选地是倾斜光栅，最优选地是倾斜的布拉格光栅，其向光波导和光栅提供扭转依赖的集合光传输光谱。通过检测通过光栅传输的光辐射的强度对应变化（12），可以检测波导和光栅的集体光透射光谱的变化（由施加到波导的扭转量的变化引起）光源（5）。集体光透射光谱的变化程度取决于施加到光波导的扭转程度（扭曲）。测量从光源传输通过光栅的光辐射的强度的大小和/或感觉（即增加/减少）使得能够感测扭转。

10. 发明申请

WO2013166886A1 ANTI-THEFT METHOD, DEVICE AND SYSTEM FOR PORTABLE COMPUTER EQUIPMENT 审中-公开
标题翻译：防盗方法，便携式计算机设备的装置和系统
公开(公告)号：WO2013166886A1
公开(公告)日：2013-11-14
申请号：PCT/CN2013/072986
申请日：2013-03-21
申请人： ZHANG, Lin
发明人： ZHANG, Lin
IPC分类号： G06F21/00
CPC分类号： G06F21/00 , G06F21/88
摘要： The present invention provides an anti-theft method, device and system for portable computer equipment. Hardware information of a mobile terminal and a portable computer equipment of a user is bounded in advance, and the binding information is stored in a server at network side. When the user finds that the portable computer equipment is stolen, the user can use the mobile terminal to send an anti-theft instruction to the network side. After the server receives the anti-theft instruction and verifies that it is correct, the server triggers the portable computer equipment at an appropriate time to start the anti-theft management measures. Therefore, when the user finds the portable computer equipment is stolen, the user does not have to remember anything and can directly use one key of the mobile terminal to start anti-theft management measures and the risk of data leakage can be reduced as much as possible.
摘要翻译：本发明提供一种用于便携式计算机设备的防盗方法，装置和系统。用户的移动终端和便携式计算机设备的硬件信息被预先约束，并且绑定信息被存储在网络侧的服务器中。当用户发现便携式计算机设备被盗时，用户可以使用移动终端向网络侧发送防盗指令。服务器接收到防盗指令并验证其是否正确后，服务器会在适当的时候触发便携式计算机设备启动防盗管理措施。因此，当用户发现便携式计算机设备被盗用时，用户不需要记住任何东西，并且可以直接使用移动终端的一个密钥来启动防盗管理措施，并且可以减少数据泄漏的风险可能。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式