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1. 发明申请

WO2006127719A2 PREDICTION OF THORACIC FLUID ACCUMULATION 审中-公开
标题翻译：胸腔积液的预测
公开(公告)号：WO2006127719A2
公开(公告)日：2006-11-30
申请号：PCT/US2006019937
申请日：2006-05-23
申请人： CARDIAC PACEMAKERS INC , STAHMANN JEFFREY E , NI QUAN , HARTLEY JESSE W
发明人： STAHMANN JEFFREY E , NI QUAN , HARTLEY JESSE W
CPC分类号： A61B5/0537 , A61B5/0538 , A61N1/3627 , A61N1/365 , A61N2001/0585
摘要： This patent document discusses, among other things, systems, devices, and methods for predicting an occurrence of impending thoracic fluid accumulation and in one example, invoking a responsive therapy, such as to prevent or minimize the consequences of the impending thoracic fluid accumulation. One example of the present systems, devices, and methods senses or receives at least one parameter that is statistically associated with impending thoracic fluid accumulation from a subject. Using such parameter(s), a probability of impending thoracic fluid accumulation is estimated. A list of parameters determines which values are recurrently sensed or received at various desired time intervals. Another example of the present systems, devices, and methods weights the sensed or received parameter value(s) to compute the probability estimate of impending thoracic fluid accumulation. A responsive preventive thoracic fluid accumulation therapy or other therapy is selected and activated using the probability estimate of impending thoracic fluid accumulation.
摘要翻译：该专利文献尤其涉及用于预测即将到来的胸腔积液的发生的系统，装置和方法，并且在一个示例中，引用响应性治疗，例如防止或最小化即将到来的胸腔积液的后果。本系统，装置和方法的一个示例感测或接收至少一个与来自受试者的即将到来的胸腔积液相关联的参数。使用这样的参数，估计即将到来的胸腔积液的概率。参数列表确定以各种期望的时间间隔反复感测或接收哪些值。本系统，装置和方法的另一个例子对感测或接收的参数值进行加权，以计算即将到来的胸腔积液的概率估计。使用即将到来的胸腔积液的概率估计来选择和激活反应性预防性胸腔积液治疗或其他治疗。

2. 发明申请

WO2006121845A2 MINIMIZING HEMODYNAMIC COMPROMISE DURING POST-MI PACING 审中-公开
标题翻译：在心肌梗死后最小化血液动力学反应
公开(公告)号：WO2006121845A2
公开(公告)日：2006-11-16
申请号：PCT/US2006017388
申请日：2006-05-05
申请人： CARDIAC PACEMAKERS INC , PASTORE JOSEPH M , SALO RODNEY W , HARTLEY JESSE W , KRAMER ANDREW P , STAHMANN JEFFREY E
发明人： PASTORE JOSEPH M , SALO RODNEY W , HARTLEY JESSE W , KRAMER ANDREW P , STAHMANN JEFFREY E
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/3684
摘要： A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an assessment of cardiac function in order to balance the beneficial effects of stress reduction with hemodynamic compromise.
摘要翻译：描述了用于递送预激发起搏以预防或减少心肌梗塞后的心脏重塑的方法和装置。根据心脏功能的评估调节预激励起搏，以平衡应力减少与血液动力学妥协的有益效果。

3. 发明申请

WO0124877A9 THRESHOLD SENSE IN A CARDIAC RHYTHM MANAGEMENT DEVICE 审中-公开
标题翻译：心理健康管理设备中的阈值感知
公开(公告)号：WO0124877A9
公开(公告)日：2002-08-15
申请号：PCT/US0041031
申请日：2000-09-29
申请人： CARDIAC PACEMAKERS INC
发明人： ZHANG GENG , ZHU QINGSHENG , MEPHAM LAURA , HARTLEY JESSE W
IPC分类号： A61N1/368 , A61N1/37
CPC分类号： A61N1/3704 , A61N1/368
摘要： A method and apparatus for automatically adjusting the sensing threshold of cardiac rhythm management devices. The invention is particularly suited for implementation in devices such as implantable cardiac pacemakers and implantable cardioverter/defibrillators. A method and apparatus are provided in which a noise level and signal level for a sensing channel are determined for each cardiac cycle with the sensing threshold of the channel being adjusted in accordance therewith.
摘要翻译：一种用于自动调节心律管理装置感测阈值的方法和装置。本发明特别适用于诸如可植入心脏起搏器和植入式心律转复器/去纤颤器的装置中的实现。提供了一种方法和装置，其中针对每个心动周期确定用于感测通道的噪声电平和信号电平，同时根据该通道的感测阈值进行调整。

4. 发明申请

WO2005028029A3 PATIENT MONITORING, DIAGNOSIS, AND/OR THERAPY SYSTEMS AND METHODS 审中-公开
标题翻译：患者监测，诊断和/或治疗系统和方法
公开(公告)号：WO2005028029A3
公开(公告)日：2005-09-29
申请号：PCT/US2004030787
申请日：2004-09-17
申请人： CARDIAC PACEMAKERS INC
发明人： STAHMANN JEFFREY E , LEE KENT , HARTLEY JESSE W , NI QUAN , HATLESTAD JOHN D , ZHU QINGSHENG , SIEJKO KRZYSZTOF J
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/042 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/08 , A61B5/083 , A61B5/085 , A61B5/087 , A61B5/103 , A61B5/113 , A61M15/00 , A61M16/00 , A61M16/10 , A61N1/18 , A61N1/20 , A61N1/362 , A61N1/365 , A61N1/37
CPC分类号： A61B5/4818 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/02405 , A61B5/0421 , A61B5/0422 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/0809 , A61B5/0836 , A61B5/087 , A61B5/103 , A61B5/1116 , A61B5/113 , A61B5/145 , A61B5/14539 , A61B5/14542 , A61B5/4035 , A61B5/4519 , A61B5/6814 , A61B5/6823 , A61B5/6828 , A61B5/686 , A61B5/6891 , A61B5/7275 , A61B2562/0219 , A61M16/0051 , A61M16/026 , A61M16/0666 , A61M16/10 , A61M2016/0021 , A61M2016/0036 , A61M2016/0039 , A61M2016/0042 , A61M2202/0208 , A61M2205/3303 , A61M2205/3306 , A61M2205/3375 , A61M2205/3561 , A61M2205/3592 , A61M2205/52 , A61M2230/04 , A61M2230/10 , A61M2230/202 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/435 , A61M2230/50 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/3601 , A61N1/362 , A61N1/3627 , A61N1/365 , A61N1/36514 , A61N1/36535 , A61N1/36557 , A61N1/36578 , A61N1/36585 , A61N1/36592 , A61N1/37
摘要： Systems and methods for monitoring, diagnosing, and/or treating a patient are provided. One or more individual medical procedures may be utilized to monitor, diagnose and/or treat the patient. Two or more of the individual medical procedures or may be used in combination to provide more comprehensive patient monitoring, diagnosis and/or therapy. One or more functions of two or more individual medical procedures may be used in combination to enhance patient monitoring, diagnosis and/or therapy. The medical procedures may be coordinated. Coordinated medical procedures may involve cooperative operation of two or more of the individual processes. Coordinated medical procedures may also involve cooperative operation of one or more functions of two or more of the individual processes.
摘要翻译：提供了用于监测，诊断和/或治疗患者的系统和方法。可以使用一个或多个单独的医疗程序来监测，诊断和/或治疗患者。两种或多种单独的医疗程序或可以组合使用以提供更全面的患者监测，诊断和/或治疗。可以组合使用两个或更多个单独医疗程序的一个或多个功能，以增强患者监测，诊断和/或治疗。医疗程序可以协调一致。协调的医疗程序可能涉及两个或多个个别过程的合作运作。协调的医疗程序还可以涉及两个或更多个独立过程的一个或多个功能的合作操作。

5. 发明申请

WO2004049930A3 DETECTION OF DISORDERED BREATHING 审中-公开
标题翻译：检测失调呼吸
公开(公告)号：WO2004049930A3
公开(公告)日：2004-09-16
申请号：PCT/US0338438
申请日：2003-12-04
申请人： CARDIAC PACEMAKERS INC
发明人： NI QUAN , HATLESTAD JOHN D , HARTLEY JESSE W , STAHMANN JEFFREY E , KIM JAEHO , LEE KENT
IPC分类号： A61B5/0205
CPC分类号： A61B5/4818 , A61B5/0205 , A61B5/4806 , A61B5/4809 , A61B5/7264
摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signal associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.
摘要翻译：用于检测呼吸紊乱的装置和方法涉及确定患者睡着并且在患者睡着时感测与指示睡眠紊乱呼吸的紊乱呼吸相关联的一个或多个信号。使用与呼吸紊乱相关的感测信号来检测睡眠紊乱的呼吸。与呼吸紊乱相关的感测信号也可用于获取一个或多个呼吸周期的呼吸模式。确定呼吸模式的特征。基于呼吸模式的特征，呼吸模式被分类为无序呼吸事件。使用可植入装置执行涉及检测无序呼吸的一个或多个过程。

6. 发明申请

WO9965565A9 AUTOMATIC THRESHOLD SENSITIVITY ADJUSTMENT FOR CARDIAC RHYTHM MANAGEMENT DEVICES 审中-公开
标题翻译： CARDIAC RHYTHM管理设备的自动阈值灵敏度调整
公开(公告)号：WO9965565A9
公开(公告)日：2000-10-05
申请号：PCT/US9913375
申请日：1999-06-14
申请人： CARDIAC PACEMAKERS INC
发明人： KIM JUNGKUK , HARTLEY JESSE W , ZHU QINGSHENG
IPC分类号： A61N1/362 , A61N1/365 , A61N1/368
CPC分类号： A61N1/3704 , A61N1/365 , A61N1/368
摘要： An implanting cardiac rhythm management device (10) includes a controller (28) adapted to receive digitized electrocardiogram signals from leads (14) placed on or in the heart, and incorporates an auto-sense algorithm which automatically adjusts the sensing threshold dependent upon an average or maximum amplitude of noise detected during a period following a sensed cardiac depolarization. The sensing threshold is automatically set on a beat to beat basis at a level such that the signal to noise ratio exceeds a preset value.
摘要翻译：植入式心律管理装置（10）包括适于从放置在心脏上或心脏上的引线（14）接收数字化心电图信号的控制器（28），并且包括自动感测算法，其根据平均值自动调节感测阈值或在感测到的心脏去极化之后的一段时间内检测到的噪声的最大幅度。感测阈值以使得信噪比超过预设值的电平自动设置在节拍上以拍打为基础。

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