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1. 发明申请

WO2005002669A2 TACHYARRHYTHMIA DETECTION AND DISCRIMINATION BASED ON CURVATURE PARAMETERS 审中-公开
标题翻译：基于曲率参数的快速心律失常检测与判别
公开(公告)号：WO2005002669A2
公开(公告)日：2005-01-13
申请号：PCT/US2004/020723
申请日：2004-06-28
申请人： CARDIAC PACEMAKERS, INC. , SWEENEY, Robert, J. , RICCI, Carlos
发明人： SWEENEY, Robert, J. , RICCI, Carlos
IPC分类号： A61N1/362
CPC分类号： G06K9/00523 , A61B5/0245 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61B5/7264 , A61N1/362 , A61N1/3962
摘要： Estimating a frequency of a sampled cardiac rhythm signal and classifying the rhythm. The received signal is sampled and transformed into a curvature series. A lobe in the curvature series corresponds to a characteristic point in the sampled series. Characteristic points are selected based on a time of a lobe in the curvature series and, in one embodiment, an amplitude of the signal at the time of the lobe. A frequency of the sampled series is estimated by autocorrelating a function of the series of the characteristic points. In one embodiment, the function is a time difference function. The rhythm is classified by plotting the timewise proximity of characteristic points derived from an atrial signal with characteristic points derived from a ventricular signal. Regions of the plot are associated with a particular rhythm and the grouping of the data corresponds to the classification.
摘要翻译：估计采样心律信号的频率并分类节奏。接收到的信号被采样并转换成曲率序列。曲率系列中的波瓣对应于采样序列中的特征点。基于曲率序列中的波瓣的时间来选择特征点，并且在一个实施例中，选择波瓣时的信号的幅度。通过对一系列特征点的函数进行自相关来估计采样序列的频率。在一个实施例中，该功能是时间差功能。通过绘制从心房信号导出的特征点与由心室信号导出的特征点的时间接近性来对节律进行分类。图的区域与特定的节奏相关联，并且数据的分组对应于分类。

2. 发明申请

WO2007133873A3 HEART FAILURE MANAGEMENT SYSTEM 审中-公开
公开(公告)号：WO2007133873A3
公开(公告)日：2007-11-22
申请号：PCT/US2007/066543
申请日：2007-04-12
申请人： CARDIAC PACEMAKERS, INC. , LIBBUS, Imad , SIEJKO, Krzysztof, Z. , BROCKWAY, Marina , SWEENEY, Robert, J.
发明人： LIBBUS, Imad , SIEJKO, Krzysztof, Z. , BROCKWAY, Marina , SWEENEY, Robert, J.
IPC分类号： A61N1/365 , A61N1/36 , A61N1/362 , A61N1/372
摘要： Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein.

3. 发明申请

WO2007024471A1 DEFIBRILLATION THRESHOLD PREDICTION METHODS AND SYSTEMS 审中-公开
标题翻译：预测阈值预测方法和系统
公开(公告)号：WO2007024471A1
公开(公告)日：2007-03-01
申请号：PCT/US2006/030829
申请日：2006-08-09
申请人： CARDIAC PACEMAKERS, INC. , WEI, Xuan , SWEENEY, Robert, J. , BOCEK, Joesph, M. , MEYER, Scott, A. , STAHMANN, Jeffrey, E. , ZHANG, Yi
发明人： WEI, Xuan , SWEENEY, Robert, J. , BOCEK, Joesph, M. , MEYER, Scott, A. , STAHMANN, Jeffrey, E. , ZHANG, Yi
IPC分类号： A61N1/39
CPC分类号： A61N1/3943
摘要： A nondefibrillating and nonfibrillation-inducing energy is delivered at a first internal thoracic location. A first resulting electrical signal is detected at a second internal thoracic location in or near a target region of a heart. A first defibrillation threshold is estimated using the nondefibrillating and nonfibrillation-inducing energy, the first resulting electrical signal, and a target electric field strength. The defibrillation threshold represents an energy that when delivered at the first internal thoracic location creates an electric field strength in the target region of the heart that meets or exceeds the target electric field strength.
摘要翻译：在第一内部胸部位置输送非去纤颤和非诱导性能量。在心脏的目标区域中或附近的第二内部胸部位置检测到第一个产生的电信号。使用非去纤颤和非原纤维诱发能量，首先得到的电信号和目标电场强度来估计第一除颤阈值。除颤阈值表示当在第一内部胸部位置处递送时在心脏的目标区域中产生满足或超过目标电场强度的电场强度的能量。

4. 发明申请

WO2012005987A3 RHYTHM DISCRIMINATION USING INFORMATION INDICATIVE OF LEAD MOTION 审中-公开
公开(公告)号：WO2012005987A3
公开(公告)日：2012-01-12
申请号：PCT/US2011/041850
申请日：2011-06-24
申请人： CARDIAC PACEMAKERS, INC. , SWEENEY, Robert, J. , SHUROS, Allan, C. , SIEJKO, Krzysztof, Z. , OLSON, David, C. , INGLE, Frank
发明人： SWEENEY, Robert, J. , SHUROS, Allan, C. , SIEJKO, Krzysztof, Z. , OLSON, David, C. , INGLE, Frank
IPC分类号： A61N1/365 , A61B5/026 , A61B5/11
摘要： Systems and methods for rhythm discrimination using the motion of an implantable lead are described. In an example, an implantable medical device can include a receiver circuit configured to be electrically coupled to an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The device can include an arrhythmia detection circuit configured to determine an arrhythmia status using the information indicative of the movement of the implantable lead and an arrhythmia classification circuit configured to determine one or more of a location or a type of an arrhythmia, using the information indicative of the movement of the implantable lead, when the arrhythmia status indicates that an arrhythmia is occurring or has occurred.

5. 发明申请

WO2008082479A1 WITHIN-PATIENT DETECTION AND BETWEEN-PATIENT STRATIFIER 审中-公开
标题翻译：患者检测和患者分层
公开(公告)号：WO2008082479A1
公开(公告)日：2008-07-10
申请号：PCT/US2007/025668
申请日：2007-12-17
申请人： CARDIAC PACEMAKERS, INC. , SACHANANDANI, Haresh, G. , SIEJKO, Krzysztof, Z. , PETERSON, Jon , CAZARES, Shelley, M. , SWEENEY, Robert, J. , STALSBERG, Kevin, J. , CARLSON, Gerrard, M.
发明人： SACHANANDANI, Haresh, G. , SIEJKO, Krzysztof, Z. , PETERSON, Jon , CAZARES, Shelley, M. , SWEENEY, Robert, J. , STALSBERG, Kevin, J. , CARLSON, Gerrard, M.
IPC分类号： A61N1/372 , A61B5/00 , A61N1/37 , G06F19/00
CPC分类号： A61N1/37282 , A61B5/0022 , A61B5/0205 , A61N1/3702 , G06F19/00 , G06F19/3418 , G16H40/63 , G16H50/20
摘要： A system comprises a patient device comprising: a communication module adapted to obtain results of a first physiological assessment, wherein the first physiological assessment includes a between-patient assessment; and an analysis module adapted to use the results to adjust one or more parameters of a second physiological assessment, wherein the second physiological assessment includes a within-patient assessment.
摘要翻译：一种系统包括患者装置，包括：适于获得第一生理学评估结果的通信模块，其中所述第一生理评估包括患者间评估; 以及适于使用所述结果来调整第二生理评估的一个或多个参数的分析模块，其中所述第二生理评估包括患者内评估。

6. 发明申请

WO2006002398A1 AUTOMATIC ORIENTATION DETERMINATION FOR ECG MEASUREMENTS USING MULTIPLE ELECTRODES 审中-公开
标题翻译：使用多个电极进行心电图测量的自动定向测定
公开(公告)号：WO2006002398A1
公开(公告)日：2006-01-05
申请号：PCT/US2005/022575
申请日：2005-06-24
申请人： CARDIAC PACEMAKERS, INC.
发明人： ZHANG, Yi , BROCKWAY, Marina , RICCI, Carlos, Alberto , HEIL, Ron , DAUM, Douglas, R. , SWEENEY, Robert, J. , MCCABE, Aaron
IPC分类号： A61B5/0452
CPC分类号： A61B5/0006 , A61B5/0031 , A61B5/04011 , A61B5/0422 , A61B5/7207 , A61B5/7217 , A61N1/3756 , G06K9/624
摘要： Cardiac monitoring and/or stimulation methods and systems provide monitoring, defibrillation and/or pacing therapies. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal using a source separation algorithm, and identifies a cardiac signal using a selected vector. The signal processor may iteratively separate signals from the plurality of composite signals until the cardiac signal is identified. The selected vector may be updated if desired or necessary. A method of signal separation involves detecting a plurality of composite signals at a plurality of locations, separating a signal using source separation, and selecting a vector that provides a cardiac signal. The separation may include a principal component analysis and/or an independent component analysis. Vectors may be selected and updated based on changes of position and/or orientation of implanted components and changes in patient parameters such as patient condition, cardiac signal-to-noise ratio, and disease progression.
摘要翻译：心脏监测和/或刺激方法和系统提供监测，除颤和/或起搏治疗。信号处理器接收与多个源相关联的多个复合信号，使用源分离算法分离信号，并使用所选择的向量来识别心脏信号。信号处理器可以迭代地分离来自多个复合信号的信号，直到识别心脏信号。如果需要或必要，可以更新所选择的向量。信号分离的方法包括在多个位置检测多个复合信号，使用源分离分离信号，以及选择提供心脏信号的向量。分离可以包括主成分分析和/或独立成分分析。可以基于植入组件的位置和/或取向的改变以及患者参数（例如患者状况，心脏信噪比和疾病进展）的变化来选择和更新载体。

7. 发明申请

WO2004006763A2 APPARATUS AND METHOD FOR USE OF CURVATURE-BASED FEATURES FOR BEAT DETECTION 审中-公开
标题翻译：使用基于曲线的特征进行BEAT检测的装置和方法
公开(公告)号：WO2004006763A2
公开(公告)日：2004-01-22
申请号：PCT/US2003/022024
申请日：2003-07-15
申请人： CARDIAC PACEMAKERS, INC.
发明人： SWEENEY, Robert, J.
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/7239 , A61N1/365

8. 发明申请

WO2002009582A3 METHOD AND APPARATUS FOR A MORPHOLOGY-PRESERVING SMOOTHING 审中-公开
公开(公告)号：WO2002009582A3
公开(公告)日：2002-02-07
申请号：PCT/US2001/041440
申请日：2001-07-26
申请人： CARDIAC PACEMAKERS, INC.
发明人： LOVETT, Eric, G. , SWEENEY, Robert, J.
IPC分类号： H03H17/02
摘要： A method and apparatus for implementing a signal morphology preservation smoothing scheme. The smoothing scheme includes generating an output signal representative of a filtered version of the input signal, wherein the output signal is generated by adaptively removing low amplitude, high frequency noise components while simultaneously preserving signal morphology of the input signal. The smoothing scheme includes comparison of a distance metric against a distance threshold to determine whether an initial smoothed version of the input signal would be oversmoothed or undersmoothed. Then the smoothing scheme appropriately increments, decrements, or maintains the initial level of smoothing to generate an optimal smoothed signal representative of the output signal.

9. 发明申请

WO2003075744A3 OPTIMIZING IMPLANTED MEDICAL DEVICE PERFORMANCE 审中-公开
公开(公告)号：WO2003075744A3
公开(公告)日：2003-09-18
申请号：PCT/US2003/006851
申请日：2003-03-06
申请人： CARDIAC PACEMAKERS, INC.
发明人： KENKNIGHT, Bruce, H. , LOVETT, Eric, G. , SWEENEY, Robert, J. , MAZAR, Scott, T. , MANICKA, Yatheendhar
IPC分类号： A61N1/08
摘要： An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as in interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic interfaces with a clinical programmer for use by a physician.

10. 发明申请

WO2002040094A3 CURVATURE-BASED FEATURE SELECTION FOR ELECTROPHYSIOLOGIC SIGNALS 审中-公开
公开(公告)号：WO2002040094A3
公开(公告)日：2002-05-23
申请号：PCT/US2001/045763
申请日：2001-10-26
申请人： CARDIAC PACEMAKERS, INC.
发明人： SWEENEY, Robert, J. , LOVETT, Eric, G.
IPC分类号： A61N1/37
摘要： A method for curvature based complex identification and classification comprises sensing a cardiac signal and computing curvatures at sample points on the sensed cardiac signal, extracting features from the computed curvatures, comparing the extracted features with a set of predetermined templates, and classifying the sensed cardiac signal based on the outcome of the comparison.

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