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1. 发明申请

WO2018115839A1 Improved Extraction Apparatus 审中-公开
公开(公告)号：WO2018115839A1
公开(公告)日：2018-06-28
申请号：PCT/GB2017/053799
申请日：2017-12-19
申请人： CAMBTEK LIMITED
发明人： MALKIN, Hugh , HASTINGS, Nicholas James , WILLIAMSON, Finbarr Charles Ronald
IPC分类号： B02C1/02 , A61J1/10 , A61J7/00 , B02C19/00
摘要： Apparatus for distributing a solid dosage form in an extraction fluid comprises: (a) a sample preparation bag for containing said solid dosage form and an extraction fluid, the bag comprising flexible walls defining a sample preparation chamber having an opening through which solid dosage forms may be passed, the sample preparation chamber comprising: (i) an opening-proximal upper reservoir zone for receiving one or more solid dosage forms via the opening; (ii) an opening-distal lower reservoir zone for containing pulverized solid dosage form and/or extraction fluid; and (iii) a pulverizing zone between the upper and lower reservoir zones, wherein the pulverizing zone comprises opposed crusher plates fixed to a portion of each of the inner surfaces of two opposed walls of the bag; (b) a jaw crusher for pulverizing said solid dosage form contained within the sample preparation bag, the crusher comprising: (i) an upper pulverizer assembly comprising a pair of opposed jaws, said jaws being moveable relative to one another and each comprising opposed upper and lower crushing surfaces for contacting the outer surfaces of the pulverizing zone of the sample preparation bag and thereby exerting a crushing force on a solid dosage form contained therein via the crusher plates of the bag; and (ii) a lower pump assembly comprising pumping means comprising a member for contacting an outer surface of the lower reservoir zone of the sample preparation bag and thereby displacing extraction fluid contained therein to the pulverizing zone thereof; wherein the opposed upper crushing surfaces are adapted to nip with a first stroke length l and at a first frequency f and the opposed lower crushing surfaces are adapted to nip with a second stroke length l 2 at a second frequency f 2, and wherein l > l 2 and f

2. 发明申请

WO2018215743A1 APPARATUS FOR AGITATING A LIQUID 审中-公开
公开(公告)号：WO2018215743A1
公开(公告)日：2018-11-29
申请号：PCT/GB2018/051368
申请日：2018-05-21
申请人： CAMBTEK LIMITED
发明人： MALKIN, Hugh , HASTINGS, Nicholas James , WILLIAMSON, Finbarr Charles Ronald
IPC分类号： B01F11/00
CPC分类号： B01F11/0065
摘要： Described is an apparatus (10) for agitating a liquid sample comprising: (a) an extraction pouch having walls (12) defining a chamber in which a liquid sample is confined, the pouch comprising a pair of opposed walls (12), at least one of which is flexible; (b) a frame (14) for holding said extraction pouch; (c) an agitator assembly comprising a roller (18), (20) adapted to roll over an outer surface of said flexible wall (12) of the extraction pouch and to exert a rolling pressure thereon, whereby a portion of the pouch is compressed such that part of the liquid sample is displaced and forced to flow within the extraction pouch, under and/ or around the roller (18, 20), so agitating it within the sample chamber; and (d) a motor operably coupled to said agitator assembly and/or to said frame (14) for reciprocating the roller (18, 20) relative to the extraction pouch.

3. 发明申请

WO2016005766A1 IMPROVED EXTRACTION APPARATUS 审中-公开
标题翻译：改进的提取装置
公开(公告)号：WO2016005766A1
公开(公告)日：2016-01-14
申请号：PCT/GB2015/052004
申请日：2015-07-10
申请人： CAMBTEK LIMITED
发明人： MALKIN, Hugh , HASTINGS, Nicholas James , GEORGE, Ian Morgan , PEARL, Martin
IPC分类号： G01N1/28 , B01F11/00 , B02C19/08 , B02C1/14 , C12M1/26 , C12M1/33
CPC分类号： A23F5/265 , B01D11/0215 , B02C19/08 , C09H3/00 , C11B1/10 , G01N1/286 , G01N2001/2866 , G01N2001/4061 , G01N2013/006
摘要： Apparatus for distributing a solid, gel, powder, granular, liquid or viscous liquid test substance in an extraction fluid comprises: a)a flow cell for holding the test substance comprising an extraction chamber of uniform cross-sectional area,a grinding surface, an extraction fluid inlet and an extract outlet; b)a grinding head disposed within the extraction chamber and adapted to reciprocate therein; and c)a recirculating pump for driving extraction fluid: (i) into the flow cell via the extraction fluid inlet; (ii) through the extraction chamber; and (iii) back to the flow cell via the extract outlet.
摘要翻译：用于在提取流体中分配固体，凝胶，粉末，颗粒，液体或粘稠液体测试物质的装置包括：a）用于保持测试物质的流动池，包括具有均匀横截面积的提取室，研磨表面，萃取液入口和提取物出口; b）设置在所述提取室内并适于在其中往复运动的研磨头; 和c）用于驱动提取流体的循环泵：（i）经由提取流体入口进入流动池; （ii）通过提取室; 和（iii）通过提取物出口返回流动池。

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