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1. 发明申请

WO2010121223A3 ELECTROMAGNETIC MOLECULAR SENSORS AND METHODS OF USING SAME 审中-公开
标题翻译：电磁分子传感器及其使用方法
公开(公告)号：WO2010121223A3
公开(公告)日：2011-01-13
申请号：PCT/US2010031517
申请日：2010-04-16
申请人： CALIFORNIA INST OF TECHN , HAJIMIRI SEYED ALI , WANG HUA
发明人： HAJIMIRI SEYED ALI , WANG HUA
IPC分类号： G01N27/72 , C12Q1/68 , G01N33/53
CPC分类号： G01N27/745 , C12Q1/6813 , C12Q1/6816 , C12Q1/6825 , C12Q1/6832 , C12Q1/6834 , C12Q2525/161 , C12Q2525/197 , C12Q2525/301 , C12Q2563/143 , C12Q2565/519 , G01N27/3278 , G01N27/72 , G01N33/54326 , G01N33/54333 , G01N2446/00 , Y10T436/143333
摘要： Devices having an electromagnetic detector for the detection of analytes are disclosed. The devices include an electromagnetic detector, including effective inductance-change magnetic detectors, and a binding moiety. The device can include an electromagnetic material that can be detected by the detector. The device is configured such that binding of an analyte to the binding moiety changes the relationship between the electromagnetic detector and the electromagnetic material such that a change in electromagnetic field is detected by the electromagnetic detector.
摘要翻译：公开了具有用于检测分析物的电磁检测器的装置。这些装置包括电磁检测器，包括有效的电感变化磁性检测器和结合部分。该装置可以包括可由检测器检测的电磁材料。该装置被配置为使得分析物与结合部分的结合改变了电磁检测器和电磁材料之间的关系，使得电磁检测器检测到电磁场的变化。

2. 发明申请

WO2010096770A3 NOISE SUPPRESSION TECHNIQUES IN HIGH PRECISION LONG-TERM FREQUENCY/TIMING MEASUREMENTS 审中-公开
标题翻译：噪声抑制技术在高精度长期频率/时序测量
公开(公告)号：WO2010096770A3
公开(公告)日：2011-01-27
申请号：PCT/US2010024933
申请日：2010-02-22
申请人： CALIFORNIA INST OF TECHN , HAJIMIRI SEYED ALI , WANG HUA , KOUSAI SHOUHEI
发明人： HAJIMIRI SEYED ALI , WANG HUA , KOUSAI SHOUHEI
IPC分类号： G01R23/20 , G01R23/02
CPC分类号： G01R29/26 , G01R31/31709
摘要： A frequency/timing measurement apparatus includes a reference source having a reference source output terminal. At least one target source has a target source output terminal. The at least one target source is communicatively coupled to the reference source. A frequency timing measurement block has a first input terminal electrically coupled to the reference source output terminal. A second input terminal is electrically coupled to the target source output terminal and at least one output terminal. The frequency timing measurement block is configured to perform a noise shaping technique to reduce measurement error attributable to a phase noise that is correlated between the reference source and the target source, and to provide a reduced correlated noise measurement at the at least one output terminal. A method to reduce correlated noise is also described.
摘要翻译：频率/定时测量装置包括具有参考源输出端的参考源。至少一个目标源具有目标源输出端。至少一个目标源通信地耦合到参考源。频率定时测量块具有电耦合到参考源输出端的第一输入端。第二输入端子电耦合到目标源输出端子和至少一个输出端子。频率定时测量块被配置为执行噪声整形技术以减少归因于在参考源和目标源之间相关的相位噪声的测量误差，并且在至少一个输出端子处提供减小的相关噪声测量。还描述了一种降低相关噪声的方法。

3. 发明申请

WO2010099350A3 LOW COST BONDING TECHNIQUE FOR INTEGRATED CIRCUIT CHIPS AND PDMS STRUCTURES 审中-公开
标题翻译：用于集成电路芯片和PDMS结构的低成本联结技术
公开(公告)号：WO2010099350A3
公开(公告)日：2011-01-06
申请号：PCT/US2010025456
申请日：2010-02-25
申请人： CALIFORNIA INST OF TECHN , WANG HUA , HAJIMIRI SEYED ALI
发明人： WANG HUA , HAJIMIRI SEYED ALI
IPC分类号： H01L21/60
CPC分类号： G01R33/1269 , B81C1/0023 , H01L24/45 , H01L24/48 , H01L24/49 , H01L24/83 , H01L2224/45144 , H01L2224/48091 , H01L2224/48227 , H01L2224/49171 , H01L2224/83193 , H01L2224/83855 , H01L2924/01013 , H01L2924/01014 , H01L2924/01079 , H01L2924/10253 , H01L2924/14 , H01L2924/1461 , H01L2924/3011 , H01L2924/00014 , H01L2924/00
摘要： Methods of bonding a structure fabricated in polydimethylsiloxane (PDMS) and an integrated circuit chip. The procedures for bonding include providing a substrate, affixing the integrated circuit to the substrate, as needed preparing the surface of the integrated circuit chip to permit bonding, aligning the PDMS structure and the features of the integrated circuit chip, and applying a bonding agent. The bonding agent is cured by exposure to a thermal regime for a suitable length of time. Depending on relative sizes, in some cases, a plural number of PDMS structures can be attached to one chip, or a single PDMS structure can be bonded to multiple chips. In some cases, the integrated circuit chip operates wirelessly. In other situations, the substrate provides electrical communication from the integrated circuit chip to electronic components.
摘要翻译：将聚二甲基硅氧烷（PDMS）制成的结构与集成电路芯片结合的方法。接合步骤包括提供衬底，将集成电路固定到衬底上，根据需要制备集成电路芯片的表面以允许接合，对准PDMS结构和集成电路芯片的特征，以及施加粘合剂。粘合剂通过暴露在热态下固化适宜的时间长度来固化。根据相对尺寸，在一些情况下，可以将多个PDMS结构附接到一个芯片，或者单个PDMS结构可以被结合到多个芯片。在某些情况下，集成电路芯片可以无线操作。在其他情况下，衬底提供从集成电路芯片到电子部件的电通信。

4. 发明申请

WO2011028248A3 ELECTRONIC SELF-HEALING METHODS FOR RADIO-FREQUENCY RECEIVERS 审中-公开
标题翻译：无线电频率接收机的电子自治方法
公开(公告)号：WO2011028248A3
公开(公告)日：2011-08-11
申请号：PCT/US2010002322
申请日：2010-08-24
申请人： CALIFORNIA INST OF TECHN , BOHN FLORIAN , HAJIMIRI SEYED ALI , WANG HUA , WANG YU-JIU
发明人： BOHN FLORIAN , HAJIMIRI SEYED ALI , WANG HUA , WANG YU-JIU
IPC分类号： H03L7/00 , H04B7/08
CPC分类号： H04B1/40 , H04B17/0085
摘要： Systems and methods for providing self-healing integrated circuits. The method is characterized in that the behavior of a circuit or a device in response to an input signal is observed. One or more operational parameters or characteristics of the circuit or the device are derived. A corrective action to bring the operational parameters or characteristics of the circuit or device within a desired range is deduced, if needed. The corrective action can be the application of a correction signal or a modification of one or more parameters or characteristics of an element in the circuit. The calculated corrective action, if needed, is applied to bring the operational parameters or characteristics of the circuit or device within the desired range. Optionally, the operational parameters or characteristics of the circuit or the device after the correction is effectuated can be checked.
摘要翻译：提供自愈式集成电路的系统和方法。该方法的特征在于，观察到响应于输入信号的电路或设备的行为。导出电路或器件的一个或多个操作参数或特性。如果需要，可以推导出将电路或设备的操作参数或特性置于所需范围内的纠正措施。校正动作可以是在电路中应用校正信号或修改元件的一个或多个参数或特性。如果需要，应用计算的校正动作将电路或设备的操作参数或特性置于所需范围内。可选地，可以检查校正后的电路或设备的操作参数或特性。

5. 发明申请

WO2009148664A3 FULLY INTEGRATED TEMPERATURE REGULATOR FOR BIOCHEMICAL APPLICATIONS 审中-公开
标题翻译：全面综合温度调节器用于生物化学应用
公开(公告)号：WO2009148664A3
公开(公告)日：2010-02-25
申请号：PCT/US2009036288
申请日：2009-03-06
申请人： CALIFORNIA INST OF TECHN , WANG HUA , HAJIMIRI SEYED ALI
发明人： WANG HUA , HAJIMIRI SEYED ALI
IPC分类号： H01L21/00 , H01L21/02 , H01L21/66
CPC分类号： G05D23/24 , G05D23/1906 , G05D23/22 , G05D23/27
摘要： The invention is an integrated temperature regulator that can be fabricated using conventional semiconductor processing technology. The integrated temperature regulator can include a reaction chamber, for example fabricated from PDMS, in which chemical or biochemical reactions of interest can be carried out. The temperature regular can also be used to regulate the temperature of some circuits, e.g. an effective-inductance-change based magnetic particle sensor, to achieve a stable operation performance, such as an improved sensitivity. The integrated temperature regulator includes as subcomponents a temperature sensing circuit that receives a thermal signal from the vicinity of the reaction chamber, a temperature reference circuit, and a temperature control circuit that controls a heater based at least in part on the difference between the sensed temperature and the reference temperature. The various subcomponents can be programmable.
摘要翻译：本发明是可以使用常规半导体处理技术制造的集成温度调节器。集成温度调节器可以包括例如由PDMS制造的反应室，其中可以进行感兴趣的化学或生物化学反应。温度常数也可用于调节某些电路的温度，例如基于有效电感变化的磁性粒子传感器，以实现稳定的操作性能，例如提高的灵敏度。集成温度调节器包括作为子部件的温度感测电路，其接收来自反应室附近的热信号，温度参考电路和温度控制电路，其至少部分地基于感测温度之间的差异来控制加热器和参考温度。各个子部件可以编程。

6. 发明申请

WO2010031016A3 A FREQUENCY-SHIFT CMOS MAGNETIC BIOSENSOR ARRAY WITH SINGLE BEAD SENSITIVITY AND NO EXTERNAL MAGNET 审中-公开
标题翻译：频率移动CMOS磁性生物传感器阵列，具有单根光纤灵敏度，无外部磁铁
公开(公告)号：WO2010031016A3
公开(公告)日：2010-06-17
申请号：PCT/US2009056887
申请日：2009-09-15
申请人： CALIFORNIA INST OF TECHN , WANG HUA , HAJIMIRI SEYED ALI
发明人： WANG HUA , HAJIMIRI SEYED ALI
IPC分类号： G01N33/48
CPC分类号： G01N27/745 , G01N33/54326 , G01N33/5438
摘要： According to one aspect, an integrated magnetic particle measurement device for detecting a presence or absence of magnetic particles in a sample volume includes at least one sensor cell having a differential sensor pair. An active sensor oscillator frequency is responsive to one or more magnetic particles situated within a sample volume. The sensor cell is configured to be operative in the absence of an externally applied magnetic field. A frequency measurement circuit provides as a time-multiplexed output a first count representative of the active sensor oscillator frequency and a second count representative of the reference sensor oscillator frequency. A calculated difference between the first count and the second count is indicative of a presence or an absence of one or more magnetic particles within the sample volume. An integrated magnetic particle measurement system array and a method for detecting one or more magnetic particles are also described.
摘要翻译：根据一个方面，用于检测样品体积中磁性颗粒存在或不存在的集成磁性颗粒测量装置包括至少一个具有差分传感器对的传感器单元。主动传感器振荡器频率响应于位于样品体积内的一个或多个磁性颗粒。传感器单元被配置为在没有外部施加的磁场的情况下操作。频率测量电路提供代表有源传感器振荡器频率的第一计数的时间复用输出和表示参考传感器振荡器频率的第二计数。第一计数和第二计数之间的计算差异表示样品体积内存在或不存在一个或多个磁性颗粒。还描述了集成磁性粒子测量系统阵列和用于检测一个或多个磁性粒子的方法。

7. 发明申请

WO2009148668A3 EFFECTIVE-INDUCTANCE-CHANGE BASED MAGNETIC PARTICLE SENSING 审中-公开
标题翻译：基于有效电感变化的磁性粒子感测
公开(公告)号：WO2009148668A3
公开(公告)日：2010-03-04
申请号：PCT/US2009036368
申请日：2009-03-06
申请人： CALIFORNIA INST OF TECHN , WANG HUA , HAJIMIRI SEYED ALI , CHEN YAN
发明人： WANG HUA , HAJIMIRI SEYED ALI , CHEN YAN
IPC分类号： G01N27/72 , G01N27/00 , G01R33/02
CPC分类号： G01R33/1269
摘要： The invention relates to an integrated measurement system to detect a quantity of magnetic particles in a sample. The measurement system includes a substrate. An electromagnetic (EM) structure disposed on the surface of the substrate is configured to receive a sample including the magnetic particles in proximity thereof. The integrated measurement system also includes an electrical current generator disposed on the surface of the substrate which is electro-magnetically coupled to the EM structure. The electrical current generator is configured to cause an electrical current to flow in the EM structure. The integrated measurement system also includes an effective inductance sensor disposed on the surface of the substrate which is configured to measure a selected one of an effective inductance and a change in effective inductance. The invention also relates to a method to determine the number of and/or the locations of the magnetic particles in a sample.
摘要翻译：本发明涉及一种用于检测样品中的磁性颗粒的量的综合测量系统。测量系统包括基板。设置在基板的表面上的电磁（EM）结构被配置为接收包括邻近的磁性颗粒的样品。集成测量系统还包括设置在基板的表面上的电流发生器，其电磁耦合到EM结构。电流发生器被配置为使得电流在EM结构中流动。集成测量系统还包括设置在衬底的表面上的有效电感传感器，其被配置为测量有效电感和有效电感的变化中选定的一个。本发明还涉及确定样品中磁性颗粒数量和/或位置的方法。

8. 发明申请

WO2013112214A3 EFFICIENT ACTIVE MULTI-DRIVE RADIATOR 审中-公开
标题翻译：高效的主动式多驱动散热器
公开(公告)号：WO2013112214A3
公开(公告)日：2013-10-03
申请号：PCT/US2012060698
申请日：2012-10-18
申请人： CALIFORNIA INST OF TECHN , BOWERS STEVEN , HAJIMIRI SEYED ALI
发明人： BOWERS STEVEN , HAJIMIRI SEYED ALI
IPC分类号： H01Q25/04 , H01Q1/36
CPC分类号： H01Q25/04 , H01Q1/38 , H01Q1/48 , H01Q7/00 , H01Q11/04
摘要： An integrated Multi-Port Driven (MPD) antenna that can be driven at many points with different signals. An integrated MPD radiating source utilizing an 8-phase ring oscillator and eight power amplifiers to drive the MPD antenna at 161GHz with a total radiated power of -2dBm and a single element EIRP of 4.6dBm has been demonstrated in silicon with single lobe well behaved radiation patterns closely matching simulation.
摘要翻译：一个集成的多端口驱动（MPD）天线，可以在多个点用不同的信号驱动。采用8相环形振荡器和8个功率放大器的集成MPD辐射源以161GHz的频率驱动MPD天线，总辐射功率为-2dBm，单元EIRP为4.6dBm，这一点已经在单叶性能良好的辐射硅模式与模拟紧密匹配。

9. 发明申请

WO2006039500A3 MULTI-ELEMENT PHASED ARRAY TRANSMITTER WITH LO PHASE SHIFTING AND INTEGRATED POWER AMPLIFIER 审中-公开
标题翻译：多元相位阵发射机，具有相移和集成功率放大器
公开(公告)号：WO2006039500A3
公开(公告)日：2007-01-18
申请号：PCT/US2005035210
申请日：2005-09-29
申请人： CALIFORNIA INST OF TECHN , NATARAJAN ARUN , KOMIJANI ABBAS , HAJIMIRI SEYED ALI
发明人： NATARAJAN ARUN , KOMIJANI ABBAS , HAJIMIRI SEYED ALI
IPC分类号： H04B1/02 , H04B7/02 , H04M1/00
CPC分类号： H01Q3/42 , H01Q3/22
摘要： A fully integrated CMOS multi-element phased-array transmitter (transmitter)includes, in part, on-chip power amplifiers (PA) (262), with integrated output matching. The transmitter is adapted to be configured as a two-dimensional 2-by-2 array or as a one dimensional l-by-4 array. The transmitter uses a two step up-conversion architecture with an IF frequency of 4.8GHz. Double-quadrature architecture for the up-conversion stages attenuates the signal at image frequencies. The phase selectors (252, 254) in each transmitter path have independent access to all the phases of the VCO (202). The double quadrature architecture results in two sets of phase selectors for each path, one for the in-phase (1) and one for the quadrature phase (Q) of the LO signal. The phase selection is done in two stages, with the first stage determining the desired VCO differential phase pair and the next stage selecting the appropriate polarity. An on-chip Balun is used for differential to single-ended conversion.
摘要翻译：完全集成的CMOS多元件相控阵发射器（发射机）部分地包括片上功率放大器（PA）（262），具有集成的输出匹配。发射机适于配置为二维2×2阵列或一维1/4乘法阵列。发射机采用两段升频转换架构，中频频率为4.8GHz。上转换级的双正交架构在图像频率衰减信号。每个发射机路径中的相位选择器（252,254）具有对VCO（202）的所有相位的独立访问。双正交架构为每个路径产生两组相位选择器，一组用于同相（1），另一组用于LO信号的正交相位（Q）。相位选择分为两个阶段，第一阶段确定期望的VCO差分相位对，下一个阶段选择适当的极性。片内平衡管用于差分到单端转换。

10. 发明申请

WO2009039289A2 EQUALIZATION OF THIRD-ORDER INTERMODULATION PRODUCTS IN WIDEBAND DIRECT CONVERSION RECEIVER 审中-公开
标题翻译：宽带直接变频接收机中三阶互调产物的均衡
公开(公告)号：WO2009039289A2
公开(公告)日：2009-03-26
申请号：PCT/US2008076874
申请日：2008-09-18
申请人： CALIFORNIA INST OF TECHN , KEEHR EDWARD , HAJIMIRI SEYED ALI
发明人： KEEHR EDWARD , HAJIMIRI SEYED ALI
IPC分类号： H04L27/01 , H04B7/005
CPC分类号： H03D7/14 , H04B1/123
摘要： A feedforward error-compensated receiver for minimizing undesired odd-order nonlinear distortion products. The receiver includes a first receiver path configured to receive an input signal. The first receiver path outputs a signal including at least one baseband (BB) frequency. At least one second receiver path is configured to receive the input signal and to provide a second receiver path output signal. The second receiver path includes at least one odd-order nonlinear distortion reference generator. The at least one odd-order nonlinear distortion reference generator and the mixer are configured to generate a synthetic odd-order nonlinear distortion signal. A combining element is configured to receive the output signal from the first path and the output signal from the second receiver path output and to combine the signals such that the odd-order nonlinear distortion signals are substantially attenuated at an output of the combining element.
摘要翻译：前馈误差补偿接收器，用于最小化不需要的奇数阶非线性失真产物。接收器包括被配置为接收输入信号的第一接收器路径。第一接收器路径输出包括至少一个基带（BB）频率的信号。至少一个第二接收器路径被配置为接收输入信号并提供第二接收器路径输出信号。第二接收机路径包括至少一个奇数阶非线性失真参考发生器。该至少一个奇数阶非线性失真参考发生器和混频器被配置为产生合成奇数阶非线性失真信号。组合元件被配置为接收来自第一路径的输出信号和来自第二接收器路径输出的输出信号并组合这些信号，使得奇数阶非线性失真信号在组合元件的输出处被显着衰减。

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