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1. 发明申请

WO2006055218A3 DEVICE COMPATIBLE WITH MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：与磁共振成像兼容的器件
公开(公告)号：WO2006055218A3
公开(公告)日：2008-12-04
申请号：PCT/US2005039067
申请日：2005-10-31
申请人： BIOPHAN TECHNOLOGIES INC , GRAY ROBERT W , COPE DAVID , GLOCKER DAVID A
发明人： GRAY ROBERT W , COPE DAVID , GLOCKER DAVID A
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2230/0054
摘要： A plurality of coated layers is disposed on an implanted device. The materials and electrical parameters of the coated layers are chosen and the geometry of the coated layers is arranged so that incident electromagnetic radiation induces currents in the coated layers that have a predetermined phase and amplitude relationship with the current induced in the implanted device.
摘要翻译：多个涂层设置在植入装置上。选择涂层的材料和电参数，并且布置涂层的几何形状，使得入射的电磁辐射在涂覆层中引起与植入装置中感应的电流具有预定相位和幅度关系的电流。

2. 发明申请

WO2006125086A3 MULTI-LAYER COATING SYSTEM AND METHOD 审中-公开
标题翻译：多层涂层系统及方法
公开(公告)号：WO2006125086A3
公开(公告)日：2007-12-27
申请号：PCT/US2006019247
申请日：2006-05-18
申请人： ISOFLUX INC , GLOCKER DAVID A
发明人： GLOCKER DAVID A
IPC分类号： B05D1/36
CPC分类号： G01R33/286
摘要： A system and method for coating implantable medical devices so that they do not interfere with MR imaging are described. Using any of the coating processes well known to those skilled in the art, e.g., physical vapor deposition such as evaporation, sputtering, or cathode arc, or chemical vapor deposition, spraying, plasma polymerization, plasma enhanced chemical vapor deposition and the like, multiple sources, including at least one source of an electrically insulating material and at least one source of an electrically conducting material, are oriented and shielded so as to coat separate sections of the implantable medical device. The object being coated is then rotated so that overlapping spiral coatings of the materials from the different coating sources are produced on the object.
摘要翻译：描述了用于涂覆可植入医疗装置以使它们不干扰MR成像的系统和方法。使用本领域技术人员熟知的任何涂覆方法，例如物理气相沉积如蒸发，溅射或阴极电弧，或化学气相沉积，喷涂，等离子体聚合，等离子体增强化学气相沉积等，多重包括电绝缘材料的至少一个源和至少一个导电材料源的源被定向和屏蔽以便涂覆可植入医疗装置的分开的部分。然后旋转被涂覆的物体，使得在物体上产生来自不同涂层源的材料的重叠螺旋涂层。

3. 发明申请

WO2005072189A3 RADIOPAQUE COATING FOR BIOMEDICAL DEVICES 审中-公开
标题翻译：放射性涂层用于生物医学装置
公开(公告)号：WO2005072189A3
公开(公告)日：2006-11-30
申请号：PCT/US2005001572
申请日：2005-01-21
申请人： ISOFLUX INC , GLOCKER DAVID A
发明人： GLOCKER DAVID A
IPC分类号： A61F2/86 , A61L31/08 , A61L31/18 , B22F7/00 , B22F7/02 , C23C14/02 , C23C14/16 , C23C30/00 , H05H1/24
CPC分类号： C23C14/165 , A61F2/86 , A61L31/088 , A61L31/18 , A61M2025/09108 , C23C14/021 , C23C30/00
摘要： A medical device has a radiopaque coating that can withstand the high strains inherent in the use of such devices without delamination. A coating of Ta is applied to a medical device, such as a stent, by vapor deposition so that the thermomechanical properties of the stent are not adversely affected.
摘要翻译：医疗装置具有不透射线的涂层，可以承受使用这种装置固有的高应变而不发生分层。通过气相沉积将Ta的涂层施加到诸如支架的医疗装置上，使得支架的热机械性能不受不利影响。

4. 发明申请

WO2005122961A3 RADIOPAQUE COATING FOR BIOMEDICAL DEVICES 审中-公开
标题翻译：放射性涂层用于生物医学装置
公开(公告)号：WO2005122961A3
公开(公告)日：2006-10-26
申请号：PCT/US2005020667
申请日：2005-06-13
申请人： ISOFLUX INC , GLOCKER DAVID A , ROMACH MARK M
发明人： GLOCKER DAVID A , ROMACH MARK M
IPC分类号： A61F2/86 , A61L31/08 , A61L31/14 , A61L31/18 , C23C30/00
CPC分类号： C23C30/00 , A61F2/86 , A61L31/088 , A61L31/146 , A61L31/18
摘要： A medical device has a porous radiopaque coating that can withstand the high strains inherent in the use of such devices without delamination. A coating of Ta is applied to a medical device, such as a stent, by vapor deposition so that the thermomechanical properties of the stent are not adversely affected. The coating preferable has high emissivity. The coating is applied via a generally oblique coating flux or a low energy coating flux.
摘要翻译：医疗装置具有多孔的不透射线涂层，可以承受使用这种装置固有的高应变而不会分层。通过气相沉积将Ta的涂层施加到诸如支架的医疗装置上，使得支架的热机械性能不受不利影响。该涂层优选具有高发射率。通过大体上倾斜的涂层焊剂或低能量涂层焊剂施加涂层。

5. 发明申请

WO2005094486A3 RADIOPAQUE COATING FOR BIOMEDICAL DEVICES 审中-公开
标题翻译：放射性涂层用于生物医学装置
公开(公告)号：WO2005094486A3
公开(公告)日：2007-11-29
申请号：PCT/US2005009651
申请日：2005-03-23
申请人： ISOFLUX INC , GLOCKER DAVID A , ROMACH MARK M
发明人： GLOCKER DAVID A , ROMACH MARK M
IPC分类号： A61F2/06 , A61L31/08 , A61L31/14 , A61L31/18 , C23C14/00 , C23C14/16 , C23C14/34
CPC分类号： C23C14/165 , A61L31/088 , A61L31/146 , A61L31/18 , C23C14/345
摘要： A medical device has a porous radiopaque coating that can withstand the high strains inherent in the use of such devices without delamination. A coating of Ta is applied to a medical device, such as a stent, by vapor deposition so that the thermomechanical properties of the stent are not adversely affected. The coating preferable has high emissivity.
摘要翻译：医疗装置具有多孔的不透射线涂层，可以承受使用这种装置固有的高应变而不会分层。通过气相沉积将Ta的涂层施加到诸如支架的医疗装置上，使得支架的热机械性能不受不利影响。该涂层优选具有高发射率。

6. 发明申请

WO0240736B1 CONICAL SPUTTERING TARGET 审中-公开
标题翻译：锥形溅射靶
公开(公告)号：WO0240736B1
公开(公告)日：2002-09-12
申请号：PCT/US0147089
申请日：2001-11-13
申请人： GLOCKER DAVID A
发明人： GLOCKER DAVID A
IPC分类号： C23C14/34 , C23C14/35 , H01J37/34
CPC分类号： H01J37/3423 , C23C14/3407 , C23C14/35 , H01J37/3405
摘要： A hollow cathode magnetron (10) for sputtering target material (12) from the inner surface of a target onto an off-spaced substrate. The magnetron (10) is in the shape of a truncated cone, also known as a conical frustum. The target cone (12) is backed by a conical cathode maintained at a predetermined voltage for attracting gas ions into the inner surface of the target cone (12) to sputter material therefrom. The sputtering plasma is made uniform over the entire surface of the target (12) by assuring that the magnitude of the component of the magnetic field tangent to the target surface is constant. The plasma is further confined to the vicinity of the target (12) using electrostatic elements. Sputter coatings on planar substrates (16) can achieve areal thickness nonuniformities of less than +/-0.2%.
摘要翻译：一种空心阴极磁控管（10），用于从目标的内表面溅射目标材料（12）到间隔开的衬底上。磁控管（10）呈截锥形，也称为圆锥台。目标圆锥体（12）由保持在预定电压的圆锥形阴极支撑，用于将气体离子吸引到目标圆锥体（12）的内表面以从其溅射材料。通过确保与目标表面相切的磁场分量的大小恒定，使溅射等离子体在靶（12）的整个表面上均匀。使用静电元件将等离子体进一步限制在靶（12）的附近。平面衬底（16）上的溅射涂层可实现小于+/- 0.2％的面积厚度不均匀性。

7. 发明申请

WO2006004645A3 POROUS COATINGS FOR BIOMEDICAL IMPLANTS 审中-公开
标题翻译：用于生物医学植入物的多孔涂层
公开(公告)号：WO2006004645A3
公开(公告)日：2007-05-18
申请号：PCT/US2005022695
申请日：2005-06-28
申请人： ISOFLUX INC , GLOCKER DAVID A , ROMACH MARK M
发明人： GLOCKER DAVID A , ROMACH MARK M
IPC分类号： B05C11/00 , A61F2/28
CPC分类号： C23C14/225 , A61F2/30767 , A61F2002/30929 , A61F2002/3098 , A61F2310/00407 , A61F2310/00449 , A61F2310/00485 , A61F2310/00497 , A61F2310/00544 , A61F2310/0088 , A61F2310/0097 , A61L27/306
摘要： A medical implant has a microscopically rough outer coating that serves to bond the implant to animal tissue. The coating is applied to the implant by physical vapor deposition. The coating preferable is applied via a generally oblique coating flux or a low energy coating flux. In some embodiments, the coating has pores. The pores can contain a drug, which can diffuse over a period of time. The coating may be partially nonporous to protect the implant from corrosion. The coating can have an outer porous layer that can bond with animal tissue easily.
摘要翻译：医疗植入物具有微观粗糙的外涂层，其用于将植入物结合到动物组织。通过物理气相沉积将涂层施加到植入物上。优选的涂层通过大体上倾斜的涂层焊剂或低能量涂层焊剂施加。在一些实施方案中，涂层具有孔。毛孔可以含有药物，其可以在一段时间内扩散。涂层可能是部分无孔的，以保护植入物免受腐蚀。涂层可以具有能够容易地与动物组织结合的外部多孔层。

8. 发明申请

WO2006017273A3 POROUS COATINGS ON ELECTRODES FOR BIOMEDICAL IMPLANTS 审中-公开
标题翻译：用于生物医学植入物的电极上的多孔涂层
公开(公告)号：WO2006017273A3
公开(公告)日：2006-10-26
申请号：PCT/US2005024666
申请日：2005-07-13
申请人： ISOFLUX INC , GLOCKER DAVID A , ROMACH MARK M
发明人： GLOCKER DAVID A , ROMACH MARK M
IPC分类号： A61N1/05
CPC分类号： A61N1/0568 , A61B5/042
摘要： An implantable electrode has a biomedically compatible, microscopically rough, metal coating that creates a high double-layer capacitance. The coating is applied to the implant by physical vapor deposition. The coating preferably is applied via a generally oblique coating flue or a law energy coating flux. In some embodiments, the coating has pores. The pores can contain a drug, which can diffuse over a period of time. The coating may be partially nonporous to protect the implant from corrosion.
摘要翻译：可植入电极具有生物相容性，微观上粗糙的金属涂层，产生高双层电容。通过物理气相沉积将涂层施加到植入物上。涂层优选通过通常倾斜的涂布烟道或法律能量涂层焊剂施加。在一些实施方案中，涂层具有孔。毛孔可以含有药物，其可以在一段时间内扩散。涂层可能是部分无孔的，以保护植入物免受腐蚀。

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