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1. 发明申请

WO2005118033A3 NEEDLE-FREE INJECTION SYSTEM 审中-公开
标题翻译：无针注射系统
公开(公告)号：WO2005118033A3
公开(公告)日：2006-05-18
申请号：PCT/US2005017927
申请日：2005-05-20
申请人： BIOJECT INC , LANDAU SERGIO , BEYLUND RYAN R , BONICATTO JAMES M , DAELLENBACH KEITH K , MILLER ROBERT A , SEDLER THEODORE WALAKA , STAYLOR JOHN L
发明人： LANDAU SERGIO , BEYLUND RYAN R , BONICATTO JAMES M , DAELLENBACH KEITH K , MILLER ROBERT A , SEDLER THEODORE WALAKA , STAYLOR JOHN L
IPC分类号： A61M5/20 , A61M5/24 , A61M5/30 , A61M5/31
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/24 , A61M2005/2407 , A61M2005/2488 , A61M2005/287 , A61M2005/3104
摘要： A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibiter may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to depressurize the device after delivery of an injection.
摘要翻译：无针注射装置，其中使用气瓶或其他加压气体源来推进活塞并强制地通过注射口排出可注射流体。当使用气体盒时，气体盒可以从初始位置移动到释放气体的致动位置以驱动喷射，并且可以采用反冲抑制器来防止气体盒回到初始位置。气瓶密封件可以设置在气体盒上，并且可与气体盒一起移动，以将气体盒密封在气体盒壳体的内壁上。无针注射装置也可以被配置为使得在活塞完全前进时密封受到影响，以便在注射输送之后使装置减压。

2. 发明申请

WO2006009839A3 INTRADERMAL INJECTION SYSTEM FOR INJECTING DNA-BASED INJECTABLES INTO HUMANS 审中-公开
标题翻译：将基于DNA的注射器注入人体的内镜注射系统
公开(公告)号：WO2006009839A3
公开(公告)日：2007-05-03
申请号：PCT/US2005021453
申请日：2005-06-17
申请人： BIOJECT INC , STOUT RICHARD R , MILLER ROBERT A , BONICATTO JAMES M
发明人： STOUT RICHARD R , MILLER ROBERT A , BONICATTO JAMES M
IPC分类号： A61M5/30 , C12M3/00
CPC分类号： A61M5/30 , A61M5/46 , C12M35/00 , C12M35/04
摘要： A system for injecting DNA-based medications into humans is provided by the present invention. The system includes a needle-free injector with an injection orifice of approximately 0.004 inches for supplying DNA-based medication at an initial pressure of from 3900 to 4300 psi, and then immediately declining to a level of about 2800 to 3800 psi, and then immediately cutting off pressure to terminate the injection. The injector includes an annular adapter (12) for spacing the injection orifice from the skin of the patient. The adapter includes an abutment against which the injector is disposed so that the orifice is spaced approximately 0.76-1.0 inch from the skin of the patient, the adapter having an inner diameter at the distal end of approximately 0.50-0.70 inches.
摘要翻译：本发明提供了一种将基于DNA的药物注入人体的系统。该系统包括具有大约0.004英寸的注射孔的无针注射器，用于在3900至4300psi的初始压力下提供基于DNA的药物，然后立即下降至约2800至3800psi的水平，然后立即切断压力以终止注射。注射器包括用于将注射孔与患者皮肤间隔开的环形适配器（12）。适配器包括抵靠件，注射器设置在支座上，使得孔口与患者皮肤间隔大约0.76-1.0英寸，适配器的远端的内径大约为0.50-0.70英寸。

3. 发明申请

WO2012115808A1 LOCALIZED HEATING TECHNIQUES INCORPORATING TUNABLE INFRARED ELEMENT(S) FOR VACUUM INSULATING GLASS UNITS, AND/OR APPARATUSES FOR SAME 审中-公开
标题翻译：包含真空绝缘玻璃单元的可控制红外线元件的本地化加热技术和/或相同的装置
公开(公告)号：WO2012115808A1
公开(公告)日：2012-08-30
申请号：PCT/US2012024796
申请日：2012-02-13
申请人： GUARDIAN INDUSTRIES , COOPER DAVID J , DEAR RYAN L , MILLER ROBERT A
发明人： COOPER DAVID J , DEAR RYAN L , MILLER ROBERT A
IPC分类号： E06B3/673 , E06B3/663
CPC分类号： E06B3/66357 , C03C27/06 , E06B3/67334
摘要： Certain example embodiments of this invention relate to edge sealing techniques for vacuum insulating glass (VIG) units. More particularly, certain example embodiments relate to techniques for providing localized heating to edge seals of units, and/or unitized ovens for accomplishing the same. In certain example embodiments, infrared (IR) heating elements are controllable to emit IR radiation at a peak wavelength in the near infrared (NIR) and/or short wave infrared (SWIR) band(s), and the peak wavelength may be varied by adjusting the voltage applied to the IR heating elements. The peak wavelength may be selected so as to preferentially heat the frit material used to form a VIG edge seal while reducing the amount of heat provided to substrates of the VIG unit. In certain example embodiments, the substrates of the VIG unit do not reach a temperature of 325 degrees C for more than 1 minute.
摘要翻译：本发明的某些示例性实施例涉及真空中空玻璃（VIG）单元的边缘密封技术。更具体地，某些示例实施例涉及用于向单元的边缘密封提供局部加热的技术和/或用于实现其的单元化炉。在某些示例性实施例中，红外线（IR）加热元件是可控制的，以在近红外（NIR）和/或短波红外（SWIR）频带中的峰值波长处发射IR辐射，并且峰值波长可以通过调整施加到IR加热元件的电压。可以选择峰值波长，以优先加热用于形成VIG边缘密封的玻璃料，同时减少提供给VIG单元的基板的热量。在某些示例性实施例中，VIG单元的基板没有达到325摄氏度的温度超过1分钟。

4. 发明申请

WO2006007554A2 ABRASIVE MACHINING MEDIA CONTAINING THERMOPLASTIC POLYMER 审中-公开
标题翻译：含有热塑性聚合物的磨料加工介质
公开(公告)号：WO2006007554A2
公开(公告)日：2006-01-19
申请号：PCT/US2005023510
申请日：2005-07-01
申请人： EXTRUDE HONE CORP , LUNN MICHAEL F , TROUP DANIEL P , MILLER ROBERT A , DELO DAVID P
发明人： LUNN MICHAEL F , TROUP DANIEL P , MILLER ROBERT A , DELO DAVID P
CPC分类号： B24B31/116
摘要： The present invention incorporates at least one thermoplastic or elastomeric polymer in abrasive flow machining media either as the sole or as one of the polymeric constituents. The presence of thermoplastic polymer imparts a greater elastomer characteristic (elasticity, compression resistance, increased relaxation times) as contrasted with traditional media. Enhanced elastomeric characteristics enable more uniform abrasive machining. In a particularly preferred embodiment, silicone- or polyorganosiloxane-based medium contains elastic silicone rubber particles dispersed therethrough to achieve increased relaxation times comparable to those attainable with the inclusion of a thermoplastic polymer.
摘要翻译：本发明将至少一种热塑性或弹性体聚合物结合到磨料流动加工介质中，作为唯一或作为聚合物组分之一。与传统介质相比，热塑性聚合物的存在赋予了更高的弹性体特性（弹性，抗压缩性，增加的松弛时间）。增强的弹性体特性可实现更均匀的磨料加工。在一个特别优选的实施方案中，基于硅氧烷或聚有机硅氧烷的介质含有分散在其中的弹性硅橡胶颗粒，以实现与包含热塑性聚合物可达到的弛豫时间相当的增加的弛豫时间。

5. 发明申请

WO0113975A3 DNA-BASED INTRAMUSCULAR INJECTION SYSTEM FOR HUMANS 审中-公开
标题翻译：基于DNA的人体内注射系统
公开(公告)号：WO0113975A3
公开(公告)日：2001-09-07
申请号：PCT/US0023001
申请日：2000-08-18
申请人： BIOJECT INC
发明人： STOUT RICHARD R , MILLER ROBERT A , BONICATTO JAMES M
IPC分类号： A61M5/30 , A61B19/00
CPC分类号： A61M5/30
摘要： A method of injecting a DNA-based injectable into a human, using a needle-free injection system (10) is provided. The method includes the steps of first pressuring an injectate (18) within an ampule (12) having a nozzle orifice (16). A peak pressure of approximately 3900-4300 psi adjacent the nozzle, is reached. Then the pressure is immediately reduced to approximately 1200-2100 psi while the injection is continuing. This distributes the DNA-based injectable throughout the muscle tissue and traumatizes the tissue. The pressure is cut-off, normally within 10 ms, to terminate the injection process.
摘要翻译：提供了使用无针注射系统（10）将基于DNA的可注射剂注射到人中的方法。该方法包括以下步骤：在具有喷嘴孔口（16）的安瓿（12）内首先加压注射器（18）。达到与喷嘴相邻的约3900-4300 psi的峰值压力。然后在喷射持续的时候立即将压力降低至约1200-2100psi。这将基于DNA的注射剂分布在整个肌肉组织中并对组织进行创伤。压力通常在10 ms内停止，以终止注射过程。

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