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    • 7. 发明申请
    • STABLE EMULSIFIABLE GEL MATRIX FOR FORMING GEL CONCENTRATE WITH AGRICULTURAL CHEMICAL, AND AQUEOUS MACROEMULSION THEREFROM
    • 用于形成具有农业化学品的凝胶浓度的稳定可乳化凝胶基质和其中的水性微乳液
    • WO1995001723A1
    • 1995-01-19
    • PCT/US1994004000
    • 1994-04-12
    • ISP INVESTMENTS INC.
    • ISP INVESTMENTS INC.NARAYANAN, Kolazi, S.
    • A01N25/04
    • B01J13/0052A01N25/04Y10S514/941Y10S514/944Y10S514/965Y10S516/902A01N43/70
    • What is provided herein is a stable, emulsifiable gel matrix for an agriculturally active chemical, which matrix will form an emulsifiable gel concentrate upon addition of the agriculturally active chemical, and upon water dilution, a highly stable aqueous macroemulsion which avoids precipitation of the active ingredient on extended storage. In addition, the inventive emulsifiable gel concentrates may contain relatively high concentrations of the agriculturally active chemical, the concentration sometimes being referred to as "loading", making it advantageous from both the economic and handling viewpoints. In one embodiment, the emulsifiable gel matrix comprises a surfactant (nonylphenol ethoxylated phosphate ester), a solvent system (N-methylpyrrolidone + N-octylpyrrolidone), a thickening agent (hydroxypropyl cellulose), a high molecular weight polymer as a viscosity enhancer and/or disintegration aid (polyvinylpyrrolidone), and optionally a polyhydric alcohol (glycerol) and an organic diluent (naphtha and other aromatic oils).
    • 本文提供的是用于农业活性化学品的稳定的可乳化的凝胶基质,该基质在添加农业活性化学物质时将形成可乳化的凝胶浓缩物,并且在水稀释时,高度稳定的水性宏观乳液避免了活性成分的沉淀 扩展存储。 此外,本发明的可乳化凝胶浓缩物可以含有相对高浓度的农业活性化学品,浓度有时被称为“加载”,从经济角度和处理观点都是有利的。 在一个实施方案中,可乳化凝胶基质包括表面活性剂(壬基酚乙氧基化磷酸酯),溶剂体系(N-甲基吡咯烷酮+ N-辛基吡咯烷酮),增稠剂(羟丙基纤维素),作为粘度增强剂的高分子量聚合物和/ 或崩解助剂(聚乙烯吡咯烷酮)和任选的多元醇(甘油)和有机稀释剂(石脑油和其他芳香油)。
    • 8. 发明申请
    • PROCESS FOR THE PRODUCTION OF PURE VINYL PYRROLIDONE
    • 制备纯乙烯吡咯烷酮的方法
    • WO1994018166A1
    • 1994-08-18
    • PCT/US1994000805
    • 1994-01-21
    • ISP INVESTMENTS INC.
    • ISP INVESTMENTS INC.COHEN, Jeffrey, M.BISS, Russell, B.
    • C07D207/267
    • C07D207/267
    • This invention relates to a process for the purification of a crude liquid N-vinylpyrrolidone product which comprises (I) product rectification by (a) subjecting said crude product containing at least 0.3 weight % of impurities to a temperature of between about 1 DEG and 5 DEG below the freezing point of said crude liquid to form a vinyl pyrrolidone crystalline phase and a liquid residue phase in a first crystallization step; (b) separating said liquid phase from said crystalline phase; (c) allowing said separated crystalline phase to warm gradually so as to liquify said crystals and (d) subjecting the liquified crystals of vinyl pyrrolidone to between 1 and 3 additional crystallization steps, each carried out by gradually cooling the liquified vinyl pyrrolidone to a temperature above that of the preceding crystallization step up to a temperature of 14.4 DEG C so as to form additional vinyl pyrrolidone crystalline and liquid residue phases with separation of vinyl pyrrolidone crystals and liquid residue phases and liquification of vinyl pyrrolidone crystals between each additional recrystallization step, recovery of N-vinyl-pyrrolidone product from the final crystallization step and (II) collecting said separated liquid residues from each crystallization step and subjecting them, sequentially, individually or collectively, to fractional crystallization in order to recover additional amounts of purified vinyl pyrrolidone product. The present process is capable of achieving up to 99.999 % purity of vinyl pyrrolidone in about 98 % recovery.
    • 本发明涉及纯液体N-乙烯基吡咯烷酮产物的纯化方法,该方法包括(I)通过(a)将含有至少0.3重量%杂质的所述粗产物处理至约1至5℃的温度来进行产物精馏 DEG低于所述粗液体的凝固点,以在第一结晶步骤中形成乙烯基吡咯烷酮结晶相和液体残余相; (b)从所述结晶相分离所述液相; (c)使所述分离的结晶相逐渐温热以使所述晶体液化,和(d)使乙烯基吡咯烷酮的液化晶体经受1至3个另外的结晶步骤,每个结晶步骤通过将液化的乙烯基吡咯烷酮逐渐冷却至温度 高于上述结晶步骤的温度至14.4℃,以便在每次附加的重结晶步骤之间分离乙烯基吡咯烷酮晶体和液体残余相并乙烯基吡咯烷酮晶体的液化形成另外的乙烯基吡咯烷酮结晶和液体残余相,回收 的N-乙烯基吡咯烷酮产物和(II)从每个结晶步骤收集所述分离的液体残余物,并依次单独或共同地对其进行分级结晶,以回收额外量的纯化的乙烯基吡咯烷酮产物。 本方法能够以约98%的回收率实现高达99.999%的乙烯基吡咯烷酮纯度。