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1. 发明申请

WO2008141288A1 DEVICES AND METHODS FOR STOMACH PARTITIONING 审中-公开
标题翻译：装置和方法进行分离
公开(公告)号：WO2008141288A1
公开(公告)日：2008-11-20
申请号：PCT/US2008/063440
申请日：2008-05-12
申请人： BAROSENSE, INC. , BALBIERZ, Daniel, J. , COLE, Dave , CREWS, Samuel, T. , SWOPE, Brett
发明人： BALBIERZ, Daniel, J. , COLE, Dave , CREWS, Samuel, T. , SWOPE, Brett
IPC分类号： A61B17/064 , A61B17/068 , A61B17/10 , A61B17/28 , A61F5/00 , A61B17/30
CPC分类号： A61F5/0086 , A61B17/0643 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/10 , A61B17/1155 , A61B17/29 , A61B2017/00349 , A61B2017/0647 , A61B2017/07228 , A61B2017/2905 , A61B2017/306 , A61F5/0083 , A61F5/0089
摘要： A device and method for remodeling or partitioning a body cavity, hollow organ or tissue tract includes graspers operable to engage two or more sections of tissue within a body cavity and to draw the engaged tissue between a first and second members of a tissue remodeling tool. The two or more pinches of tissue are held in complete or partial alignment with one another as staples or other fasteners are driven through the pinches, thus forming a four-layer tissue plication. Over time, adhesions formed between the opposed serosal layers create strong bonds that can facilitate retention of the plication over extended durations, despite the forces imparted on them by stomach movement. A cut or cut-out may be formed in the plication during or separate from the stapling step to promote edge-to-edge healing effects that will enhance tissue knitting/adhesion.
摘要翻译：用于重建或分隔体腔，中空器官或组织道的装置和方法包括可操作以接合体腔内的组织的两个或更多个部分并且将所接合的组织在组织重建工具的第一和第二构件之间拉伸的抓握器。当钉或其它紧固件通过夹持物被驱动时，两个或更多个组织的夹子彼此完全或部分地对准，从而形成四层组织折叠。随着时间的推移，相对的浆膜层之间形成的粘连产生强烈的粘结，尽管通过胃运动赋予它们的力量，但是它们可以有助于在延长的持续时间内保持脓肿。在缝合步骤期间或在与缝合步骤分开时可以在切口中形成切口或切口，以促进边缘到边缘愈合效果，从而增强组织编织/粘附。

2. 发明申请

WO2011146853A2 TISSUE-ACQUISITION AND FASTENING DEVICES AND METHODS 审中-公开
标题翻译：组织采集和紧急装置和方法
公开(公告)号：WO2011146853A2
公开(公告)日：2011-11-24
申请号：PCT/US2011/037368
申请日：2011-05-20
申请人： BAROSENSE, INC. , BALBIERZ, Daniel, J. , COLE, David , SWOPE, Bretton , HAMBLY, Pablo, R. , ENGLAND, Justen , CREWS, Samuel, T. , PURDY, Craig, Arthur
发明人： BALBIERZ, Daniel, J. , COLE, David , SWOPE, Bretton , HAMBLY, Pablo, R. , ENGLAND, Justen , CREWS, Samuel, T. , PURDY, Craig, Arthur
IPC分类号： A61B17/00 , A61F5/00
CPC分类号： A61B17/07207 , A61B17/0643 , A61B17/0644 , A61B17/0682 , A61B17/0684 , A61B17/0686 , A61B17/072 , A61B2017/00818 , A61B2017/07214 , A61B2017/081 , A61B2017/2926 , A61B2017/306 , A61F5/0086
摘要： Devices and methods for acquiring and fastening tissues folds within an internal organ, such as the stomach, and for applying the methods and devices to producing reductions in organ volume or repair of bariatric procedures, are disclosed. An exemplary method for forming a continuous laterally extending tissue fold involves forming a succession of laterally extending folds having adjacent overlapping fold portions. One exemplary tissue-acquisition device has an open-end roller-and-arm structure that allows individual tissue folds to be formed and fastened, then advanced to an adjacent region within the stomach, for capture of a new fold that will form an extension of the existing fold(s).
摘要翻译：公开了用于获取和紧固内部器官（例如胃）内的组织折叠的装置和方法，并且用于施加所述方法和装置以减少器官体积或减轻手术的修复。用于形成连续横向延伸的组织折叠的示例性方法包括形成具有相邻重叠折叠部分的一系列横向延伸的折叠。一个示例性的组织采集装置具有允许形成和紧固单个组织褶皱的开放端的辊和臂结构，然后前进到胃内的相邻区域，以捕获将形成延伸的新折叠现有的折叠。

3. 发明申请

WO2009086549A1 GASTRIC SPACE OCCUPIER SYSTEMS AND METHODS OF USE 审中-公开
标题翻译：胃肠外营养系统及其使用方法
公开(公告)号：WO2009086549A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/088581
申请日：2008-12-30
申请人： BAROSENSE INC. , COLE, David , CREWS, Samuel, T. , SWOPE, Bretton , SMITH, Andrew , LUNSFORD, John , BALBIERZ, Daniel, J.
发明人： COLE, David , CREWS, Samuel, T. , SWOPE, Bretton , SMITH, Andrew , LUNSFORD, John , BALBIERZ, Daniel, J.
IPC分类号： A61F5/00
CPC分类号： A61F5/0036 , A61F5/003
摘要： Systems for controlling obesity utilize a number of space occupiers positioned in the stomach to reduce the effective volume of the stomach. Such arrangements provides sufficient stomach volume consumption to induce weight loss, but enable use of space occupiers that are proportioned to minimize the threat of obstruction even if they should migrate into the intestine. In general, numerous small volume space occupiers are placed in the stomach such that the total volume equals or exceeds the single volume of prior art single unit space occupiers. However, each individual space occupier is proportioned so that it will pass without obstruction if it moves into the intestine.
摘要翻译：用于控制肥胖的系统利用位于胃中的多个空间占用者来减少胃的有效体积。这种布置提供足够的胃体积消耗以引起体重减轻，但是能够使用成比例的空间占用者，以尽量减少阻塞的威胁，即使它们应该迁移到肠中。通常，许多小容量空间占用者被放置在胃中，使得总体积等于或超过现有技术的单个单位空间占用者的单个体积。然而，每个单独的空间占有者是成比例的，以便如果它进入肠，它将不会阻塞。

4. 发明申请

WO2010054399A1 TISSUE ACQUISITION DEVICE AND METHOD 审中-公开
标题翻译：组织获取装置和方法
公开(公告)号：WO2010054399A1
公开(公告)日：2010-05-14
申请号：PCT/US2009/063925
申请日：2009-11-10
申请人： BAROSENSE, INC. , HAMBLY, Pablo, R. , BALBIERZ, Daniel, J. , CREWS, Samuel, T. , SWOPE, Bretton , COLE, David , SMITH, Andrew
发明人： HAMBLY, Pablo, R. , BALBIERZ, Daniel, J. , CREWS, Samuel, T. , SWOPE, Bretton , COLE, David , SMITH, Andrew
IPC分类号： A61B17/04
CPC分类号： A61B17/10 , A61B17/068 , A61B17/30 , A61B2017/2901 , A61B2017/306 , A61F5/0086
摘要： A device and method for acquiring tissue from remote regions of a hollow internal organ, such as the stomach, in preparation for tissue fastening, is disclosed. The device includes (a) an acquisition head defining first and second side-by-side tissue-acquisition chambers, (b) a vacuum channel communicating with each of said chambers, through which a vacuum may be independently applied to the first and second chambers, and a retention element for retaining tissue captured in a chamber. The device allows tissue regions, e.g., folds, to be independently captured and placed in a side-by-side configuration for stapling.
摘要翻译：公开了一种用于从中空的内部器官（例如胃）的远端区域获取组织以准备组织紧固的装置和方法。该装置包括（a）限定第一和第二并排组织采集室的采集头，（b）与每个所述腔室连通的真空通道，真空可以独立地施加到第一和第二腔室，以及用于保持捕获在腔室中的组织的保持元件。该装置允许组织区域，例如褶皱被独立地捕获并且并排放置成并排配置以进行装订。

5. 发明申请

WO2009011881A1 OVERTUBE INTRODUCER FOR USE IN ENDOSCOPIC BARIATRIC SURGERY 审中-公开
标题翻译： OVERTUBE引言用于内镜手术
公开(公告)号：WO2009011881A1
公开(公告)日：2009-01-22
申请号：PCT/US2008/008726
申请日：2008-07-17
申请人： BAROSENSE, INC. , COLE, David , HARRIS, Melanie , CASTRO, Carlos , STEWART, Jason , CREWS, Samuel, T. , BALBIERZ, Daniel, J.
发明人： COLE, David , HARRIS, Melanie , CASTRO, Carlos , STEWART, Jason , CREWS, Samuel, T. , BALBIERZ, Daniel, J.
IPC分类号： A61B1/273
CPC分类号： A61B17/0218 , A61B1/00078 , A61B1/00135 , A61B1/0051 , A61B1/2736
摘要： This application describes an overtube device that gives diagnostic and/or therapeutic access to body cavities using natural orifices of the body. The overtube includes an elongate flexible body having a distal portion deflectable in response to activation of a control cable. Proximal features of the overtube include an insufflations port and seals for minimizing loss of insufflations pressure around the shafts of instruments passed through the tube. In some embodiments, retractor elements are including on the distal portion of the overtube.
摘要翻译：该应用描述了一种使用身体天然孔的诊断和/或治疗进入体腔的外套管装置。外套管包括细长的柔性体，其具有响应于控制电缆的启动而可偏转的远侧部分。外套管的近端特征包括吹入口和密封件，用于使穿过管的仪器的轴周围的吸入压力最小化。在一些实施例中，牵开器元件包括在外套管的远端部分上。

6. 发明申请

WO2009011882A3 ENDOSCOPIC IMPLANT SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2009011882A3
公开(公告)日：2009-01-22
申请号：PCT/US2008/008729
申请日：2008-07-17
申请人： BAROSENSE, INC. , CREWS, Samuel, T. , SWOPE, Brett , ENGLAND, Justen
发明人： CREWS, Samuel, T. , SWOPE, Brett , ENGLAND, Justen
IPC分类号： A61B17/064 , A61F5/00
摘要： Disclosed is a system for endoscopically implanting a medical implant within a body cavity such as a human stomach. The system includes one or more anchors positionable within one or more openings formed in tissue within the body cavity, such as cutouts formed in plicated body tissue. Tools are disclosed for positioning the anchors within the openings, and for coupling the implant to the anchors.

7. 发明申请

WO2010127311A1 PLICATION TAGGING DEVICE AND METHOD 审中-公开
标题翻译：电子标签设备和方法
公开(公告)号：WO2010127311A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/033284
申请日：2010-04-30
申请人： BAROSENSE, INC. , CREWS, Samuel, T. , SWOPE, Bretton , ENGLAND, Justen , COLE, David , CASTRO, Carlos, E.
发明人： CREWS, Samuel, T. , SWOPE, Bretton , ENGLAND, Justen , COLE, David , CASTRO, Carlos, E.
IPC分类号： A61B17/068
CPC分类号： A61B17/068 , A61B17/00234 , A61B17/0643 , A61B17/0644 , A61B17/0684 , A61B17/07292 , A61B17/1155 , A61B2017/00539 , A61B2017/00818 , A61B2017/2927 , A61B2017/306 , A61B2217/005 , A61B2217/007
摘要： An improvement in a stapling device and method designed to capture a tissue fold between first and second members in the device and to staple and cut the fold to form a stapled tissue plication with a hole therein is disclosed. The improvement includes an engagement assembly (252) in the first member movable from a retracted position in the first member to an extended position in the second member, and releasably attached to second member, an anchor assembly that includes the anchor (220), wherein (i) movement of the engagement assembly (252) from its retracted to its extended position, through a tissue fold captured in the device between the first and second device members, is operable to engage the anchor (220), and (ii) movement of the engagement assembly, with the anchor (220) engaged therewith, back toward its retracted position, is effective to pull at least a portion of the anchor (220) through the hole in the stapled tissue plication formed by the device.
摘要翻译：公开了一种缝合装置和方法的改进，其被设计成捕获装置中的第一和第二构件之间的组织折叠并且缝合和切割折痕以形成其中具有孔的缝合组织褶皱。该改进包括第一构件中的接合组件（252），其可从第一构件中的缩回位置移动到第二构件中的延伸位置，并且可释放地附接到第二构件，包括锚固件（220）的锚固组件，其中（i）接合组件（252）从其缩回到其延伸位置的移动通过在第一和第二装置构件之间的装置中捕获的组织折叠可操作以接合锚固件（220），和（ii）移动所述接合组件具有与其接合的所述锚固件（220）朝向其缩回位置的方向，以有效地将所述锚固件（220）的至少一部分穿过由所述装置形成的缝合组织褶皱中的孔。

8. 发明申请

WO2010129608A1 ENDOSCOPIC IMPLANT SYSTEM AND METHOD 审中-公开
标题翻译：内窥镜植入系统及方法
公开(公告)号：WO2010129608A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/033623
申请日：2010-05-04
申请人： BAROSENSE, INC. , CREWS, Samuel, T. , SWOPE, Bretton , ENGLAND, Justen
发明人： CREWS, Samuel, T. , SWOPE, Bretton , ENGLAND, Justen
IPC分类号： A61F5/00 , A61B17/064 , A61B17/115
CPC分类号： A61B17/29 , A61B2017/003 , A61B2017/00827 , A61B2017/0641 , A61F5/0086 , A61F5/0089
摘要： A system and device for implanting a food implant in a patient's stomach, by coupling the implant to a plurality of tissue-plication anchors already placed in the stomach, are disclosed. The device includes an elongate shaft assembly for accessing the stomach transorally, and on which the implant can be carried, and a plurality of cable members mounted on the shaft assembly. The cable members are disposed on the shaft assembly along a distal section thereof, and releasably attached to the shaft assembly's distal end. After a cable member engages a tissue-plication anchor, retracting the cable is operable to first release the member from a holder at the the distal end of the shaft assembly, then pull a portion of the anchor through an aperture in the implant. This process is repeated for each anchor in the stomach for attaching the implant to the stomach.
摘要翻译：公开了一种用于将食物植入物植入病人胃中的系统和装置，其通过将植入物联接到已经放置在胃中的多个组织沉积锚固件。该装置包括细长轴组件，用于经腹进入胃，并且其上可承载植入物，以及安装在轴组件上的多个线缆构件。电缆构件沿其远端部分设置在轴组件上，并且可释放地附接到轴组件的远端。在电缆部件接合组织折叠锚固件之后，缩回电缆可操作以首先从轴组件的远端处的保持器释放构件，然后通过植入物中的孔拉动锚固件的一部分。对于胃中的每个锚重复该过程，以将植入物附接到胃。

9. 发明申请

WO2006039612A2 MIXING AND DISPENSING FLUID COMPONENTS OF A MULTICOMPONENT COMPOSITION 审中-公开
标题翻译：混合和分配多组分组分的流体组分
公开(公告)号：WO2006039612A2
公开(公告)日：2006-04-13
申请号：PCT/US2005/035405
申请日：2005-09-30
申请人： ANGIOTECH BIOMATERIALS CORP. , CREWS, Samuel, T.
发明人： CREWS, Samuel, T.
IPC分类号： B67D5/60
CPC分类号： A61B17/0057 , A61B17/8833 , A61B2017/00495 , A61B2017/0065 , A61B2017/8838 , B01F5/0647 , B01F13/0023 , B05C17/00553
摘要： A device for dispensing a multicomponent composition comprising a mixture of different fluid components includes a first and at least a second fluid component inlet. The device also includes a mixing area located downstream from the fluid component inlets and an outlet extending from the mixing area. Each of the fluid component inlets is adapted to communicate with a source of a different fluid component. The mixing area is adapted to receive a flow of a first and at least second fluid component. Within the mixing area, the flow of the first fluid component is disrupted to allow mixing with the flow of a second fluid component to form a flow of multicomponent composition. The mixing area is further adapted to disrupt the flow of the multicomponent composition before the flow of the multicomponent composition exits through the outlet.
摘要翻译：用于分配包含不同流体组分的混合物的多组分组合物的装置包括第一和至少第二流体组分入口。该装置还包括位于流体部件入口下游的混合区域和从混合区域延伸的出口。每个流体组分入口适于与不同流体组分的源连通。混合区域适于接收第一和至少第二流体组分的流动。在混合区域内，第一流体组分的流动被破坏以允许与第二流体组分的流动混合以形成多组分组合物流。混合区域还适于在多组分组合物流过出口之前破坏多组分组合物的流动。

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