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1. 发明申请

WO2014008289A2 STAPLER FOR FORMING MULTIPLE TISSUE PLICATIONS 审中-公开
标题翻译：用于形成多组织装置的包装机
公开(公告)号：WO2014008289A2
公开(公告)日：2014-01-09
申请号：PCT/US2013049125
申请日：2013-07-02
申请人： BAROSENSE INC
发明人： COLE DAVID , FERRO JESICA , SWOPE BRETTON , GRUBB TYLER , BALBIERZ DANIEL
IPC分类号： B25C5/02
CPC分类号： A61B17/068 , A61B17/07292 , A61B17/1155 , A61B2017/00539 , A61B2017/00876 , A61B2017/07271 , A61B2017/306
摘要： A stapling device for forming multiple tissue plications without needing to reload the device between plications is described. The device includes staple and anvil housings that move toward and away from a tissue-capture position. A cartridge holder in the staple housing supports a cartridge with multiple groups of offset staple slots, where the slots in each group are circularly arrayed about a cartridge center axis. A staple driver in the staple housing carries a plurality of arms for engaging and ejecting the staples in a first group of staples in the cartridge, when a tissue fold is captured between the cartridge assembly and anvil in the anvil housing. When the staple driver is retracted, after a tissue plication is formed, the cartridge assembly and tissue drive are indexed to eject the next- up group of staples.
摘要翻译：描述了用于形成多个组织浸润而不需要在管腔之间重新装载装置的吻合装置。该装置包括朝向和远离组织捕获位置移动的缝钉和砧座壳体。钉仓壳体中的墨盒支架支撑具有多组胶印缝隙槽的墨盒，其中每组中的槽围绕墨盒中心轴线圆形排列。当钉盒组件和砧座壳体中的砧座之间抓住组织折叠时，订书钉壳体中的订书钉驱动器承载多个臂，用于在钉仓中的第一组订书钉中接合和弹出订书钉。当订书钉驱动器缩回时，在组织折痕形成之后，盒组件和纸巾驱动器被分度以排出下一组订书钉。

2. 发明申请

WO2009011882A3 ENDOSCOPIC IMPLANT SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2009011882A3
公开(公告)日：2009-01-22
申请号：PCT/US2008/008729
申请日：2008-07-17
申请人： BAROSENSE, INC. , CREWS, Samuel, T. , SWOPE, Brett , ENGLAND, Justen
发明人： CREWS, Samuel, T. , SWOPE, Brett , ENGLAND, Justen
IPC分类号： A61B17/064 , A61F5/00
摘要： Disclosed is a system for endoscopically implanting a medical implant within a body cavity such as a human stomach. The system includes one or more anchors positionable within one or more openings formed in tissue within the body cavity, such as cutouts formed in plicated body tissue. Tools are disclosed for positioning the anchors within the openings, and for coupling the implant to the anchors.

3. 发明申请

WO2009011882A2 ENDOSCOPIC IMPLANT SYSTEM AND METHOD 审中-公开
标题翻译：内窥镜植入系统及方法
公开(公告)号：WO2009011882A2
公开(公告)日：2009-01-22
申请号：PCT/US2008008729
申请日：2008-07-17
申请人： BAROSENSE INC , CREWS SAMUEL T , SWOPE BRETT , ENGLAND JUSTEN
发明人： CREWS SAMUEL T , SWOPE BRETT , ENGLAND JUSTEN
IPC分类号： A61B17/064 , A61B17/068
CPC分类号： A61F5/0086 , A61B17/0643 , A61B17/0644 , A61B17/128 , A61B2017/00862 , A61B2017/0647 , A61F5/0003 , A61F5/0079 , A61F5/0083 , A61F5/0089
摘要： Disclosed is a system for endoscopically implanting a medical implant within a body cavity such as a human stomach. The system includes one or more anchors positionable within one or more openings formed in tissue within the body cavity, such as cutouts formed in plicated body tissue. Tools are disclosed for positioning the anchors within the openings, and for coupling the implant to the anchors.
摘要翻译：公开了一种用于将体内植入物内窥镜植入体腔（例如人胃）内的系统。该系统包括可定位在形成在体腔内的组织中的一个或多个开口内的一个或多个锚固件，例如形成在穿孔的身体组织中的切口。公开了用于将锚固件定位在开口内并且用于将植入物联接到锚固件的工具。

4. 发明申请

WO2010054404A1 MULTI-FIRE STAPLING SYSTEMS AND METHODS FOR DELIVERING ARRAYS OF STAPLES 审中-公开
标题翻译：多层消防系统和传送堆叠阵列的方法
公开(公告)号：WO2010054404A1
公开(公告)日：2010-05-14
申请号：PCT/US2009/063930
申请日：2009-11-10
申请人： BAROSENSE, INC , BALBIERZ, Daniel, J. , HAMBLY, Pablo, R. , STEWART, Jason, S. , COLE, David
发明人： BALBIERZ, Daniel, J. , HAMBLY, Pablo, R. , STEWART, Jason, S. , COLE, David
IPC分类号： A61B17/04
CPC分类号： A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/07214 , A61B2017/07228 , A61B2017/07271 , A61F5/0086
摘要： A device for acquiring and stapling multiple tissues regions within a subject's stomach, by introducing the device transorally into the stomach, is disclosed. The device includes a multi-fire staple head designed for reciprocal motion along an axis between a compact condition in which the head can be inserted into the stomach transυrally and an expanded tissue-acquisition condition, a shaft to which the head is attached and by which the head in its compact condition can he introduced transorally into the stomach, and a tissue-acquisition device for acquiring tissue within the stomach. Also disclosed is a method for acquiring and stapling multiple tissues regions within a patient's stomach, a mυlti-fire stapler device that indexes different rows of staples, and a multi-first stapler device that with multiple staple cartridges.
摘要翻译：公开了一种用于通过将装置经胃导入胃内来获取和装订受试者胃内的多个组织区域的装置。该装置包括设计成用于沿着轴线往复运动的多点火钉头头，其紧凑状态可以在头部可以横向插入胃中，扩张的组织获取状态，头部附接到其上的轴和通过这种方式，可以将其处于紧凑状态的头部经腹导入胃中，以及用于获取胃内的组织的组织采集装置。还公开了一种用于获取和装订患者胃内的多个组织区域的方法，用于对不同行钉进行索引的多个装订器装置，以及具有多个订书钉盒的多第一订书机装置。

5. 发明申请

WO2010054399A1 TISSUE ACQUISITION DEVICE AND METHOD 审中-公开
标题翻译：组织获取装置和方法
公开(公告)号：WO2010054399A1
公开(公告)日：2010-05-14
申请号：PCT/US2009/063925
申请日：2009-11-10
申请人： BAROSENSE, INC. , HAMBLY, Pablo, R. , BALBIERZ, Daniel, J. , CREWS, Samuel, T. , SWOPE, Bretton , COLE, David , SMITH, Andrew
发明人： HAMBLY, Pablo, R. , BALBIERZ, Daniel, J. , CREWS, Samuel, T. , SWOPE, Bretton , COLE, David , SMITH, Andrew
IPC分类号： A61B17/04
CPC分类号： A61B17/10 , A61B17/068 , A61B17/30 , A61B2017/2901 , A61B2017/306 , A61F5/0086
摘要： A device and method for acquiring tissue from remote regions of a hollow internal organ, such as the stomach, in preparation for tissue fastening, is disclosed. The device includes (a) an acquisition head defining first and second side-by-side tissue-acquisition chambers, (b) a vacuum channel communicating with each of said chambers, through which a vacuum may be independently applied to the first and second chambers, and a retention element for retaining tissue captured in a chamber. The device allows tissue regions, e.g., folds, to be independently captured and placed in a side-by-side configuration for stapling.
摘要翻译：公开了一种用于从中空的内部器官（例如胃）的远端区域获取组织以准备组织紧固的装置和方法。该装置包括（a）限定第一和第二并排组织采集室的采集头，（b）与每个所述腔室连通的真空通道，真空可以独立地施加到第一和第二腔室，以及用于保持捕获在腔室中的组织的保持元件。该装置允许组织区域，例如褶皱被独立地捕获并且并排放置成并排配置以进行装订。

6. 发明申请

WO2009011881A1 OVERTUBE INTRODUCER FOR USE IN ENDOSCOPIC BARIATRIC SURGERY 审中-公开
标题翻译： OVERTUBE引言用于内镜手术
公开(公告)号：WO2009011881A1
公开(公告)日：2009-01-22
申请号：PCT/US2008/008726
申请日：2008-07-17
申请人： BAROSENSE, INC. , COLE, David , HARRIS, Melanie , CASTRO, Carlos , STEWART, Jason , CREWS, Samuel, T. , BALBIERZ, Daniel, J.
发明人： COLE, David , HARRIS, Melanie , CASTRO, Carlos , STEWART, Jason , CREWS, Samuel, T. , BALBIERZ, Daniel, J.
IPC分类号： A61B1/273
CPC分类号： A61B17/0218 , A61B1/00078 , A61B1/00135 , A61B1/0051 , A61B1/2736
摘要： This application describes an overtube device that gives diagnostic and/or therapeutic access to body cavities using natural orifices of the body. The overtube includes an elongate flexible body having a distal portion deflectable in response to activation of a control cable. Proximal features of the overtube include an insufflations port and seals for minimizing loss of insufflations pressure around the shafts of instruments passed through the tube. In some embodiments, retractor elements are including on the distal portion of the overtube.
摘要翻译：该应用描述了一种使用身体天然孔的诊断和/或治疗进入体腔的外套管装置。外套管包括细长的柔性体，其具有响应于控制电缆的启动而可偏转的远侧部分。外套管的近端特征包括吹入口和密封件，用于使穿过管的仪器的轴周围的吸入压力最小化。在一些实施例中，牵开器元件包括在外套管的远端部分上。

7. 发明申请

WO2008033409A1 ENDOSCOPIC PLICATION DEVICE AND METHOD 审中-公开
标题翻译：内窥镜装置及方法
公开(公告)号：WO2008033409A1
公开(公告)日：2008-03-20
申请号：PCT/US2007/019833
申请日：2007-09-12
申请人： BAROSENSE, INC. , CREWS, Sam , SWODE, Brett , COLE, Dave , SMITH, Andrew
发明人： CREWS, Sam , SWODE, Brett , COLE, Dave , SMITH, Andrew
IPC分类号： A61B17/068 , A61B17/072
CPC分类号： A61B17/1155 , A61B17/0218 , A61B17/068 , A61B17/072 , A61B17/07292 , A61B17/1114 , A61B17/115 , A61B17/1285 , A61B2017/00535 , A61B2017/00827 , A61B2017/07214 , A61B2017/07228 , A61B2017/1139 , A61B2017/1157 , A61B2017/306 , A61F5/0036
摘要： In a method of stapling layers of tissue within a body cavity, an engaging instrument is passed between a stapler cartridge and anvil and used to engage a region of tissue. The engaging instrument is retracted to move the engaged tissue into the stapling position, and driving staples from the cartridge through at least two layers of the engaged tissue. The method and associated system may be used to form plications in body tissue, such as stomach wall tissue. Staples simultaneously driven through tissue may simultaneously capture a reinforcing elements positioned adjacent the cartridge and/or anvil prior to stapling.
摘要翻译：在缝合体腔内的组织层的方法中，接合装置在吻合器钉仓和砧之间通过并用于啮合组织区域。接合装置缩回以将接合的组织移动到装订位置，并且通过至少两层的接合组织从钉仓驱动订书钉。该方法和相关系统可用于在身体组织如胃壁组织中形成斑点。通过组织同时驱动的订书钉可以在装订之前同时捕获邻近盒和/或砧座定位的加强元件。

8. 发明申请

WO2011146853A3 TISSUE-ACQUISITION AND FASTENING DEVICES AND METHODS 审中-公开
标题翻译：组织采集和紧急装置和方法
公开(公告)号：WO2011146853A3
公开(公告)日：2012-01-05
申请号：PCT/US2011037368
申请日：2011-05-20
申请人： BAROSENSE INC , BALBIERZ DANIEL J , COLE DAVID , SWOPE BRETTON , HAMBLY PABLO R , ENGLAND JUSTEN , CREWS SAMUEL T , PURDY CRAIG ARTHUR
发明人： BALBIERZ DANIEL J , COLE DAVID , SWOPE BRETTON , HAMBLY PABLO R , ENGLAND JUSTEN , CREWS SAMUEL T , PURDY CRAIG ARTHUR
IPC分类号： A61B17/00 , A61F5/00
CPC分类号： A61B17/07207 , A61B17/0643 , A61B17/0644 , A61B17/0682 , A61B17/0684 , A61B17/0686 , A61B17/072 , A61B2017/00818 , A61B2017/07214 , A61B2017/081 , A61B2017/2926 , A61B2017/306 , A61F5/0086
摘要： Devices and methods for acquiring and fastening tissues folds within an internal organ, such as the stomach, and for applying the methods and devices to producing reductions in organ volume or repair of bariatric procedures, arc disclosed. An exemplary method for forming a continuous laterally extending tissue fold involves forming a succession of laterally extending folds having adjacent overlapping fold portions. One exemplary tissue - acquisition device (50) comprises a support frame (52); an elongate roller (54) mounted on the frame for rotation about the roller's long axis. Said roller includes tissue - engaging structure for engaging tissue and advancing the engaged tissue in the direction of roller rotation. Said device further comprises a roller driver for rotating the roller in a tissue - advancing direction; an arm (56) mounted on said frame at a position spaced from and confronting said roller so that a two- layer tissue fold can be formed therebetween when tissue is advanced into and through the device as the roller is rotated; and a vacuum conduit (68) in said frame for connecting an external vacuum source to said roller or to said arm, to hold one layer of a two- layer tissue fold by vacuum adherence, as tissue is being advanced into and through the device by rotation of the roller.
摘要翻译：公开了用于获取和紧固内部器官（例如胃）内的组织折叠并且用于施加所述方法和装置以减少器官体积或减轻手术的修复的装置和方法。用于形成连续横向延伸的组织折叠的示例性方法包括形成具有相邻重叠折叠部分的一系列横向延伸的折叠。一个示例性组织采集装置（50）包括支撑框架（52）; 安装在框架上用于围绕辊的长轴线旋转的细长辊（54）。所述辊包括组织接合结构，用于接合组织并沿辊轮旋转方向推进啮合组织。所述装置还包括用于在组织前进方向上旋转辊的辊驱动器; 臂（56），其在与所述辊隔开并面对所述辊的位置处安装在所述框架上，使得当所述辊旋转时，当组织进入并穿过所述装置时，可以在其间形成两层组织折叠; 以及在所述框架中的真空导管（68），用于将外部真空源连接到所述辊或所述臂，以通过真空附着来保持一层双层组织折叠，因为组织正被进入和穿过该装置辊的旋转。

9. 发明申请

WO2011146853A2 TISSUE-ACQUISITION AND FASTENING DEVICES AND METHODS 审中-公开
标题翻译：组织采集和紧急装置和方法
公开(公告)号：WO2011146853A2
公开(公告)日：2011-11-24
申请号：PCT/US2011/037368
申请日：2011-05-20
申请人： BAROSENSE, INC. , BALBIERZ, Daniel, J. , COLE, David , SWOPE, Bretton , HAMBLY, Pablo, R. , ENGLAND, Justen , CREWS, Samuel, T. , PURDY, Craig, Arthur
发明人： BALBIERZ, Daniel, J. , COLE, David , SWOPE, Bretton , HAMBLY, Pablo, R. , ENGLAND, Justen , CREWS, Samuel, T. , PURDY, Craig, Arthur
IPC分类号： A61B17/00 , A61F5/00
CPC分类号： A61B17/07207 , A61B17/0643 , A61B17/0644 , A61B17/0682 , A61B17/0684 , A61B17/0686 , A61B17/072 , A61B2017/00818 , A61B2017/07214 , A61B2017/081 , A61B2017/2926 , A61B2017/306 , A61F5/0086
摘要： Devices and methods for acquiring and fastening tissues folds within an internal organ, such as the stomach, and for applying the methods and devices to producing reductions in organ volume or repair of bariatric procedures, are disclosed. An exemplary method for forming a continuous laterally extending tissue fold involves forming a succession of laterally extending folds having adjacent overlapping fold portions. One exemplary tissue-acquisition device has an open-end roller-and-arm structure that allows individual tissue folds to be formed and fastened, then advanced to an adjacent region within the stomach, for capture of a new fold that will form an extension of the existing fold(s).
摘要翻译：公开了用于获取和紧固内部器官（例如胃）内的组织折叠的装置和方法，并且用于施加所述方法和装置以减少器官体积或减轻手术的修复。用于形成连续横向延伸的组织折叠的示例性方法包括形成具有相邻重叠折叠部分的一系列横向延伸的折叠。一个示例性的组织采集装置具有允许形成和紧固单个组织褶皱的开放端的辊和臂结构，然后前进到胃内的相邻区域，以捕获将形成延伸的新折叠现有的折叠。

10. 发明申请

WO2009117533A3 ENDOSCOPIC STAPLING DEVICES AND METHODS 审中-公开
标题翻译：内窥镜钉钉装置和方法
公开(公告)号：WO2009117533A3
公开(公告)日：2009-11-12
申请号：PCT/US2009037586
申请日：2009-03-18
申请人： BAROSENSE INC , COLE DAVID , SMITH ANDREW
发明人： COLE DAVID , SMITH ANDREW
IPC分类号： A61B17/115
CPC分类号： A61B17/072 , A61B17/064 , A61B17/115 , A61B17/32053 , A61B2017/00539 , A61B2017/00818 , A61B2017/07271 , A61B2017/306 , A61F5/0013 , A61F5/0083
摘要： Described herein is a stapling device and method used to apply one or more fasteners to body tissue. In one embodiment, a fastener-applying device, which is preferably a stapler, is passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed staplers allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver staples for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention, After one or more plications are formed, medical devices may optionally be coupled to the plication(s) for retention within the stomach.
摘要翻译：本文描述了用于将一个或多个紧固件施加到身体组织的吻合装置和方法。在一个实施例中，优选为吻合器的紧固件施加装置经口腔进入胃中，并且用于通过从胃内部接合组织并向内拉动胃组织来折叠胃组织。在所公开的实施例中，组织被向内拉入真空室中，使得胃外部上的浆膜组织的部分被定位为彼此面对。所公开的吻合器允许组织的相对部分移动成彼此接触，并且优选地递送吻合钉以维持组织部分之间的接触，至少直到它们之间形成浆膜粘合。这些步骤中的每一步都可以完全从胃内部进行，因此可以消除对任何外科手术或腹腔镜介入的需要。在形成一个或多个折叠之后，医疗装置可以可选地连接到折（以保留在胃。

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