专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1989010947A1 PROTECTIVE COATING FOR BOAT HULLS AND METHOD OF APPLYING THE SAME 审中-公开
标题翻译：船用保护涂层及其应用方法
公开(公告)号：WO1989010947A1
公开(公告)日：1989-11-16
申请号：PCT/US1989002056
申请日：1989-05-12
申请人： ADVANCED POLYMER SYSTEMS, INC. , WEIDMAN, Larry, G.
发明人： ADVANCED POLYMER SYSTEMS, INC.
IPC分类号： C08L77/02
CPC分类号： C09D177/02 , C08K3/08 , C08K3/22 , C08K5/57 , C09D5/1662 , C08L77/02
摘要： An improved, environnmentally safe protective coating for marine surfaces is provided which is specially formulated for application to boat hulls for resisting marine growth thereon while minimizing release of toxic antifoulants into the environment. The coatings of the invention can therefore be used on boat hulls for preventing marine growth without the severe pollution effects associated with conventional antifoulant paints. The coatings are preferably made from powdered mixtures which include respective quantities of a polyamide such as Nylon 11, and a metallic antifoulant. In certain cases, the compositions may include an inorganic porous carrier such as carbon black, as well as glass spheres. In particularly perferred embodiments, use is made of an antifoulant such as elemental tin or copper or mixtures thereof together with an adhesive and an algicide. Application of the mixture to marine surfaces involves providing a supersonic gas stream, passing the gas stream through an electric arc thereby heating the gas stream and converting a portion thereof to plasma, injecting a quantity of the powdered mixture into the heated gas stream substantially downstream from the arc so as to melt the powder without overheating it, and then spraying the melted mixture onto a surface whereupon it cools and provides a bonded protective coating thereon.
摘要翻译：提供了一种改进的，环境安全的海洋表面保护涂层，其特别配制用于船体上用于抵抗海洋生长，同时将有毒防污剂的释放最小化到环境中。因此，本发明的涂层可以用于船体上用于防止海洋生长而没有与常规防污涂料相关的严重污染影响。涂层优选由粉末混合物制成，其包括各自量的聚酰胺如尼龙11和金属防污剂。在某些情况下，组合物可以包括无机多孔载体，例如炭黑，以及玻璃球。在特别推荐的实施方案中，使用防污剂如元素锡或铜或其混合物与粘合剂和杀藻剂一起使用。将混合物应用于海洋表面包括提供超音速气流，使气流通过电弧，从而加热气流并将其部分转化为等离子体，将大量粉末状混合物注入加热气流中，电弧以使粉末熔化而不使其过热，然后将熔融的混合物喷射到其上冷却的表面上，并在其上提供粘合的保护涂层。

2. 发明申请

WO1997025980A1 TOPICAL DELIVERY OF DRUGS TO THE LOWER GASTROINTESTINAL TRACT 审中-公开
标题翻译：将药物局部输送到下胃肠道手术
公开(公告)号：WO1997025980A1
公开(公告)日：1997-07-24
申请号：PCT/US1996000512
申请日：1996-01-16
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , BERLINER, David, L. , NACHT, Sergio
IPC分类号： A61K09/22
CPC分类号： A61K9/2077 , A61K9/1635 , A61K9/2846 , A61K9/5036
摘要： Treatment of certain diseases of the colon by orally ingesting a suitable dosage form having a composition containing a plurality of rigid cross-linked polymer beads, each defining a substantially noncollapsible internal pore network, and a therapeutically effective amount of an active agent or drug in said pore network. The dosage form is treated with a polysaccharide, such as pectin, which is specifically attacked by colonic bacteria to permit drug release in the colon.
摘要翻译：通过口服摄取具有包含多个刚性交联聚合物珠粒的组合物的合适剂型治疗结肠的某些疾病，每个限定基本上非可收缩的内部孔网络，以及治疗有效量的所述活性剂或药物孔网。剂型用诸如果胶的多糖处理，其被结肠细菌特异性攻击以允许在结肠中释放药物。

3. 发明申请

WO1992018222A1 PREPARATION AND USE OF SOLID BEADS HAVING CONTROLLED CHARACTERISTICS 审中-公开
标题翻译：具有控制特性的固体珠的制备和使用
公开(公告)号：WO1992018222A1
公开(公告)日：1992-10-29
申请号：PCT/US1992003212
申请日：1992-04-20
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , LIAU, Christine, J., Y. , PAPACOSTA, Kemon, John , MAZAS, Constantin , EURY, Robert, P. , NACHT, Sergio
IPC分类号： B01D33/15
CPC分类号： A61M1/3693 , C08F2/22 , G01N33/5094
摘要： Processes for preparing and using controlled characteristic beads are disclosed, the process of making the beads including the steps combining at least one monoethylenically unsaturated monomer with a polyethylenically unsaturated monomer and a monomer-soluble initiator to form a monomer phase; combining the monomer phase with a liquid in which the monomer phase is substantially immiscible to form a reaction mixture such that when the monomer phase is vinyl in nature the liquid also includes a high molecular weight, high charge density surfactant, and when the monomer phase is acrylic in nature the liquid includes an organic polymer colloid suspending agent; agitating the reaction mixture at an initial speed and temperature for a time sufficient to homogenize the reaction mixture, thereby producing first intermediate droplets, and subsequently reducing the agitation speed to a level sufficient to allow limited coalescence of the first intermediate droplets to form second intermediate droplets having size distribution with less than about 30 % variance from the mean; and polymerizing the second intermediate droplets to form solid, substantially non-porous beads. One method of using controlled characteristic beads includes combining the beads produced by the process with a sample containing two separable components and centrifuging the sample for a time and at a rate sufficient to produce distinct bands of components.
摘要翻译：公开了制备和使用受控特征珠粒的方法，制备珠粒的方法包括将至少一种单烯属不饱和单体与单体可溶性引发剂结合以形成单体相的步骤; 将单体相与其中单体相基本上不混溶以形成反应混合物的液体组合，使得当本质上单体相是乙烯基时，液体还包括高分子量，高电荷密度的表面活性剂，并且当单体相是丙烯酸性质的液体包括有机聚合物胶体悬浮剂; 在初始速度和温度下搅拌反应混合物足以使反应混合物均匀化的时间，从而产生第一中间液滴，随后将搅拌速度降低至足以允许第一中间液滴的有限聚结形成第二中间液滴其尺寸分布与平均值小于约30％的差异; 并聚合第二中间液滴以形成固体，基本上无孔的珠粒。使用受控特征珠的一种方法包括将通过该方法产生的珠粒与含有两种可分离组分的样品组合并将样品离心一段时间并以足以产生不同组分带的速率离心。

4. 发明申请

WO1989010818A1 APPARATUS AND METHOD FOR APPLYING PLASMA FLAME SPRAYED POLYMERS 审中-公开
标题翻译：用于施加等离子体喷涂聚合物的装置和方法
公开(公告)号：WO1989010818A1
公开(公告)日：1989-11-16
申请号：PCT/US1989002053
申请日：1989-05-12
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , WEIDMAN, Larry, G.
IPC分类号： B23K09/00
CPC分类号： B05B7/205 , H05H1/42
摘要： An apparatus and method for applying plasma flame sprayed polymers is provided which permits the application of a thin coating of heat fusible material onto substrate material. The apparatus is used with a conventional plasma generator (12) whereby materials such as nylon or other synthetic polymers may be injected into the plasma stream to melt the powder without overheating it. The apparatus includes a central water-cooled nozzle (58), surrounded by an open co-axial flow area within a barrel (16). The polymer is evenly distributed on the substrate due to the co-axial flow of the plasma stream and air drawn through the flow area. A source of vacuum (20) connected to the apparatus (10) draws fumes generated by the melted polymers into an opening surrounding the bore (98) at the front of the barrel (16), whereby the vacuumed gases may be filtered. The apparatus (10) may be used in a method of applying plasma flame sprayed polymer compositions to a surface.
摘要翻译：提供了一种用于施加等离子火焰喷涂聚合物的设备和方法，其允许将热熔材料的薄涂层施加到基底材料上。该装置与传统的等离子体发生器（12）一起使用，由此将诸如尼龙或其它合成聚合物的材料注入到等离子体流中以熔化粉末而不过热。该设备包括中心水冷喷嘴（58），其由筒体（16）内的开放的同轴流动区域包围。由于等离子体流的同轴流动和通过流动区域吸入的空气，聚合物均匀地分布在基板上。连接到设备（10）的真空源（20）将熔化的聚合物产生的烟雾吸引到在筒体（16）的前部周围的孔（98）周围的开口中，从而可以对抽真空的气体进行过滤。装置（10）可以用于将等离子火焰喷涂的聚合物组合物施加到表面上的方法中。

5. 发明申请

WO1997027843A2 TARGETED DELIVERY OF DRUGS TO THE LOWER GASTROINTESTINAL TRACT 审中-公开
标题翻译：有针对性地将药物递送至下部胃肠道手术
公开(公告)号：WO1997027843A2
公开(公告)日：1997-08-07
申请号：PCT/US1997000946
申请日：1997-01-29
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , BERLINER, David, L. , NACHT, Sergio
IPC分类号： A61K09/20
CPC分类号： A61K9/2846 , A61K9/127 , A61K9/2081 , A61K9/4866 , A61K9/4891
摘要： This invention relates to compositions for the treatment of certain diseases of the distal intestinal tract. Specifically, the invention relates to coated delivery vehicles such as nonporous microspheres, microscapsules, non-crosslinked porous beads or liposomes, for the sustained delivery of a therapeutically effective amount of an active agent. The composition is coated with a substance, e.g., a polysaccharide such as pectin, which is specifically attacked by intestinal bacteria to permit the release of the active agent in the distal intestinal tract, particularly the colon.
摘要翻译：本发明涉及用于治疗远端肠道的某些疾病的组合物。具体地，本发明涉及涂覆的递送载体，例如无孔微球，微孔，非交联多孔珠或脂质体，用于持续递送治疗有效量的活性剂。组合物涂覆有物质，例如多糖，例如果胶，其被肠细菌特异性攻击，以允许活性剂在远端肠道，特别是结肠中释放。

6. 发明申请

WO1993006757A1 SYSTEM AND METHOD FOR DEODORANT DELIVERY IN FOOTWEAR 审中-公开
标题翻译：系统和方法在鞋子中进行交付
公开(公告)号：WO1993006757A1
公开(公告)日：1993-04-15
申请号：PCT/US1992008527
申请日：1992-10-07
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , WILLIFORD, John, H.
IPC分类号： A43B13/38
CPC分类号： A43B17/102 , A43B1/0045
摘要： An article (10) for the pressure-actuated release of the powder composition (36) comprises a resilient layer (14) having a plurality of discrete reservoirs (20) therein. Each reservoir (20) contains an isolated quantity of an active powder composition (36), and usually a permeable layer (40) covers the open apertures of the reservoirs (20). As the article (10) is compressed, the powder (36) is forced outward through the permeable layer (40) and into the surrounding environment. In a preferred example, the article (10) is a shoe insole (10) and the active composition is an anti-microbial powder (36), usually being an anti-microbial agent which is absorbed into porous particles.

7. 发明申请

WO1991007101A1 METHODS AND COMPOSITIONS FOR FLAVORING ORALLY-DELIVERED PRODUCTS 审中-公开
标题翻译：用于挥发交付产品的方法和组合物
公开(公告)号：WO1991007101A1
公开(公告)日：1991-05-30
申请号：PCT/US1990006091
申请日：1990-10-24
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , WILLIFORD, John, H. , KATZ, Martin , NACHT, Sergio , CHENG, Chung-Heng , PATEL, Rajesh, A. , PICARD, Brian, J.
IPC分类号： A23G03/30
CPC分类号： A23G4/20 , A23G3/346 , A23G2220/02 , A23L27/74 , A61K9/1635
摘要： Flavored food and pharmaceutical compositions include one or more flavor additives incorporated within polymeric particles, usually within an internal pore network defined by individual polymeric particles. The polymeric particles are, in turn, dispersed within and/or over a surface of an orally-deliverable matrix material, which is usually a solid or semi-solid substrate. In the case of chewable compositions, the flavor additives will be released into the orally-deliverable matrix material as the composition is chewed and held in the mouth, thus prolonging the flavor of the composition. In the case of dried powders and mixes, the flavor will typically be made available as the product is consumed or be released into the matrix material as the composition is further processed. When two flavors are combined with the polymeric particles, the relative amounts of the additives can be selected to provide simultaneous release and exhaustion of the additives.
摘要翻译：调味食品和药物组合物包括掺入聚合物颗粒内的一种或多种风味添加剂，通常在由单个聚合物颗粒限定的内部孔网内。聚合物颗粒又分散在通常为固体或半固体基质的经口输送的基质材料的表面内和/或之上。在可咀嚼的组合物的情况下，当组合物咀嚼并保持在口中时，风味添加剂将释放到口服递送的基质材料中，从而延长组合物的风味。在干燥粉末和混合物的情况下，当组合物进一步加工时，通常会将产品消耗或释放到基质材料中，从而获得风味。当两种口味与聚合物颗粒结合时，可以选择添加剂的相对量以提供添加剂的同时释放和耗尽。

8. 发明申请

WO1997039746A1 METHOD OF AND COMPOSITION FOR TREATING DISORDERS OF THE SKIN USING VITAMIN K 审中-公开
标题翻译：使用维生素K治疗皮肤疾病的方法和组合物
公开(公告)号：WO1997039746A1
公开(公告)日：1997-10-30
申请号：PCT/US1997006464
申请日：1997-04-22
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , ELSON, Melvin, L.
IPC分类号： A61K31/12
CPC分类号： A61K9/0014 , A61K31/122 , A61K47/10 , A61K47/14 , A61K47/186 , A61K47/24
摘要： A method of treatment of blood disorders of the skin and other conditions of the skin which include, but are not limited to, rosacea, spider veins and inflammatory conditions of the skin by the topical application of a vitamin K composition is described. The composition comprises a vitamin K composition mixture which includes a number of the following substances: natural and synthetic vitamin K, 95 % ethyl alcohol SD40, isopropyl alcohol 99 %, benzyl alcohol, lecithin granules, isopropyl palmitate NF, propyl paraben, methyl paraben, Pluronic F-127 NF, Dowicil 200 and preserved water. The concentrations of the substituent compounds vary in the different formulations of the vitamin K composition.
摘要翻译：描述了通过局部施用维生素K组合物治疗皮肤的血液病症和皮肤的其它病症的方法，其包括但不限于红斑痤疮，蜘蛛静脉和皮肤的炎性病症。该组合物包含维生素K组合物混合物，其包含许多以下物质：天然和合成维生素K，95％乙醇SD40，异丙醇99％，苄醇，卵磷脂颗粒，棕榈酸异丙酯NF，对羟基苯甲酸丙酯，对羟基苯甲酸甲酯， Pluronic F-127 NF，Dowicil 200和保存水。取代基化合物的浓度在维生素K组成的不同配方中不同。

9. 发明申请

WO1993010826A1 PRESSURIZED PRODUCT DELIVERY SYSTEMS 审中-公开
标题翻译：加压产品交付系统
公开(公告)号：WO1993010826A1
公开(公告)日：1993-06-10
申请号：PCT/US1992010465
申请日：1992-12-04
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , FROIX, Michael , SHIPLEY, Larry , LIAU, Christine, J., Y. , NGUYEN, Hien , KHOR, Sok, Leng
IPC分类号： A61L09/04
CPC分类号： B65D83/60 , A61L9/14 , F17C11/00
摘要： An apparatus for dispensing pressurized material is comprised of a container, a polymeric matrix having a network of macropores located within the container, and a propellant that may be reversibly sorbed with the network of macropores so as to desorb as the partial pressure of the propellant within the container decreases. The network of pores is substantially non-swellable upon sorption and desorption of the propellant during filling and use of the dispensing apparatus. The polymeric matrix may comprise aggregates of macroporous polymeric particles in which the particles define a substantially non-collapsible pore network and the aggregates define interstitial spaces between the particles, and the interstitial spaces are substantially larger than the pore network. The dispensing apparatus (10), the product to be dispensed (24), the propellant (2), a pressurized container (12) including a valve (16) and actuator (26) (commonly a push button), having a flexible bag or diaphragm (14), the container nozzle (18), a rigid macroporous polymeric matrix (20) and the propellant chamber (22) outside of container (12).

10. 发明申请

WO1997020812A1 RETINYL ESTERS OF 'alpha'-HYDROXY ACIDS FOR TOPICAL IMPROVEMENT OF SKIN FUNCTION AND APPEARANCE 审中-公开
标题翻译： α-羟基酸酯用于皮肤功能和外观的局部改善
公开(公告)号：WO1997020812A1
公开(公告)日：1997-06-12
申请号：PCT/US1996019580
申请日：1996-12-02
申请人： ADVANCED POLYMER SYSTEMS, INC.
发明人： ADVANCED POLYMER SYSTEMS, INC. , BIGGER, Thomas, J. , NACHT, Sergio , NG, Steve
IPC分类号： C07C403/12
CPC分类号： C07C403/12 , A61K8/671 , A61K31/22 , A61Q19/08 , C07C2601/16
摘要： Esters of retinol and alpha -hydroxy acids are unusually effective as skin conditioners, with significant reductions in the irritation problems characteristic of retinol and alpha -hydroxy acids in nonesterified form.
摘要翻译：视黄醇和α-羟基酸的酯类作为皮肤调理剂是非常有效的，显着降低非酯化形式的视黄醇和α-羟基酸的刺激性问题。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式