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1. 发明申请

WO2012170369A1 WATER-BASED AMINE CURING AGENTS FOR CURABLE RESIN SYSTEMS 审中-公开
标题翻译：用于可固化树脂体系的水基胺固化剂
公开(公告)号：WO2012170369A1
公开(公告)日：2012-12-13
申请号：PCT/US2012/040818
申请日：2012-06-05
申请人： HUNTSMAN ADVANCED MATERIALS AMERICAS LLC , KINCAID, Derek, Scott , ZHOU, Hui
发明人： KINCAID, Derek, Scott , ZHOU, Hui
IPC分类号： C08K3/20
CPC分类号： C09D163/00 , C08G59/1477 , C08K3/013 , C08K5/17 , Y10T428/31511 , C08L63/00
摘要： The present disclosure relates to a water-based amine curing agent which is a reaction product obtained from the reaction of an aqueous epoxy resin dispersion and a polyamine component. The water-based amine curing agent may be used as part of a two component coating system in the curing of modified or unmodified liquid or pre- dispersed curable resin.
摘要翻译：本公开涉及一种水性胺固化剂，其是由水性环氧树脂分散体和多胺成分的反应得到的反应产物。水性胺固化剂可用作改性或未改性液体或预分散固化树脂固化中双组分涂料体系的一部分。

2. 发明申请

WO2009140530A3 MULTI-SCALE METHOD FOR MULTI-PHASE FLOW IN POROUS MEDIA 审中-公开
标题翻译：多孔介质中多相流的多尺度方法
公开(公告)号：WO2009140530A3
公开(公告)日：2010-06-24
申请号：PCT/US2009044002
申请日：2009-05-14
申请人： CHEVRON USA INC , SCHLUMBERGER CA LTD , SCHLUMBERGER SERVICES PETROL , LOGINED BV , PRAD RESERACH AND DEV LTD , LEE SEONG H , ZHOU HUI , TCHELEPI HAMDI A
发明人： LEE SEONG H , ZHOU HUI , TCHELEPI HAMDI A
IPC分类号： G06F17/50
CPC分类号： E21B43/00 , E21B47/10 , G06F17/5018 , G06F2217/16
摘要： A multi-scale method to efficiently determine the fine-scale saturation arising from multi-phase flow in a subsurface reservoir is disclosed. The method includes providing a simulation model that includes a fine-scale grid defining a plurality of fine-scale cells, and a coarse-scale grid defining a plurality of coarse-scale cells that are aggregates of the fine-scale cells. The coarse-scale cells are partitioned into saturation regions responsive to velocity and/or saturation changes from the saturation front. A fine-scale saturation is determined for each region and the saturation regions are assembled to obtain a fine-scale saturation distribution. A visual display can be output responsive to the fine-scale saturation distribution.
摘要翻译：公开了一种多尺度方法，用于有效地确定由地下储层中的多相流产生的细小饱和饱和度。该方法包括提供包括限定多个精细尺度单元格的精细尺度网格的模拟模型，以及限定作为精细尺度单元的聚集的多个粗尺度单元的粗尺度网格。粗尺度单元被分成饱和区域，其响应于来自饱和度前沿的速度和/或饱和度变化。确定每个区域的精细饱和度，并组装饱和区域以获得精细尺度饱和度分布。可以根据精细尺度的饱和度分布输出视觉显示。

3. 发明申请

WO2010027976A3 INDIRECT-ERROR-BASED, DYNAMIC UPSCALING OF MULTI-PHASE FLOW IN POROUS MEDIA 审中-公开
公开(公告)号：WO2010027976A3
公开(公告)日：2010-03-11
申请号：PCT/US2009/055612
申请日：2009-09-01
申请人： CHEVRON U.S.A. INC. , SCHLUMBERGER CANADA LIMITED , SERVICES PETROLIERS SCHLUMBERGER , LOGINED B.V. , PRAD RESERACH AND DEVELOPMENT LIMITED , LEE, Seong, H. , ZHOU, Hui , TCHELEPI, Hamdi, A.
发明人： LEE, Seong, H. , ZHOU, Hui , TCHELEPI, Hamdi, A.
IPC分类号： G06F19/00 , G06F11/00
摘要： Computer-implemented systems and methods are provided for an upscaling approach based on dynamic simulation of a given model. A system and method can be configured such that the accuracy of the upscaled model is continuously monitored via indirect error measures. If the indirect error measures are bigger than a specified tolerance, the upscaled model is dynamically updated with approximate fine-scale information that is reconstructed by a multi-scale finite volume method. Upscaling of multi-phase flow can include flow information in the underlying fine-scale. Adaptive prolongation and restriction operators are applied for flow and transport equations in constructing an approximate fine-scale solution.

4. 发明申请

WO2009140530A2 MULTI-SCALE METHOD FOR MULTI-PHASE FLOW IN POROUS MEDIA 审中-公开
标题翻译：多孔介质中多相流的多尺度方法
公开(公告)号：WO2009140530A2
公开(公告)日：2009-11-19
申请号：PCT/US2009/044002
申请日：2009-05-14
申请人： CHEVRON U.S.A. INC. , SCHLUMBERGER CANADA LIMITED , SERVICES PETROLIERS SCHLUMBERGER , LOGINED B.V. , PRAD RESERACH AND DEVELOPMENT LIMITED , LEE, Seong, H. , ZHOU, Hui , TCHELEPI, Hamdi, A.
发明人： LEE, Seong, H. , ZHOU, Hui , TCHELEPI, Hamdi, A.
IPC分类号： G06G7/50
CPC分类号： E21B43/00 , E21B47/10 , G06F17/5018 , G06F2217/16
摘要： A multi-scale method to efficiently determine the fine-scale saturation arising from multi-phase flow in a subsurface reservoir is disclosed. The method includes providing a simulation model that includes a fine-scale grid defining a plurality of fine-scale cells, and a coarse-scale grid defining a plurality of coarse-scale cells that are aggregates of the fine-scale cells. The coarse-scale cells are partitioned into saturation regions responsive to velocity and/or saturation changes from the saturation front. A fine-scale saturation is determined for each region and the saturation regions are assembled to obtain a fine-scale saturation distribution. A visual display can be output responsive to the fine-scale saturation distribution.
摘要翻译：公开了一种多尺度方法，用于有效地确定由地下储层中的多相流产生的细小饱和饱和度。该方法包括提供包括限定多个精细尺度单元的精细尺度网格的模拟模型，以及限定作为精细尺度单元的聚集的多个粗尺度单元的粗尺度网格。粗尺度单元被分为饱和区域，其响应于来自饱和度前沿的速度和/或饱和度变化。确定每个区域的精细饱和度，并组装饱和区域以获得精细的饱和度分布。可以响应于精细尺度饱和度分布输出视觉显示。

5. 发明申请

WO2018223233A1 A PROCESSING PLATFORM AND A METHOD FOR PROCESSING DOMAIN NAME TRANSACTIONS AT A REMOTE DOMAIN NAME REGISTRY 审中-公开
公开(公告)号：WO2018223233A1
公开(公告)日：2018-12-13
申请号：PCT/CA2018/050677
申请日：2018-06-06
申请人： ZHOU, Hui , MOHAN, Cedarampattu , WANG, Xuhui , SINGER, Steven
发明人： ZHOU, Hui , MOHAN, Cedarampattu , WANG, Xuhui , SINGER, Steven
IPC分类号： H04L12/16 , H04L29/06
摘要： Within a particular Top Level Domain (TLD), domain name allocation and domain name ownership may be subject to certain restrictions requiring verification. A processing platform and a method for facilitating domain name transactions between a registrant and a domain name registry are disclosed. The transactions include a verification of domain names, domain name entities or both, where said transactions are associated with a request from the registrant. The processing platform and domain name registry may be remotely located relative to one another.

6. 发明申请

WO2017113258A1 GAS TURBINE, SEALING COVER, AND MANUFACTURING METHOD THEREOF 审中-公开
标题翻译：燃气轮机，密封盖及其制造方法
公开(公告)号：WO2017113258A1
公开(公告)日：2017-07-06
申请号：PCT/CN2015/100003
申请日：2015-12-30
申请人： SIEMENS AKTIENGESELLSCHAFT , CHEN, Guo Feng , DUAN, Rui Chun , LI, Chang Peng , YAO, Zhi Qi , ZHOU, Hui Wen
发明人： CHEN, Guo Feng , DUAN, Rui Chun , LI, Chang Peng , YAO, Zhi Qi , ZHOU, Hui Wen
IPC分类号： F02C7/28 , F01D5/18
CPC分类号： F01D5/3015 , B22F3/1055 , B22F5/009 , B33Y80/00 , F05D2250/291 , F05D2260/204 , F05D2260/22141
摘要： A sealing cover (20) used for a gas turbine (100). The gas turbine (100) comprises at least one turbine disk (143), and the sealing cover (20) is used to cover the turbine disk (143). A side wall (22a) of the sealing cover (20) is provided with a first air hole (222) and a second air hole (223). A spacing is formed between the first air hole (222) and the second air hole (223). A cooling passage (226) and a plurality of ribs (225) are provided within the sealing cover (20). The cooling passage (226) is in communication with the first air hole (222) and the second air hole (223), and the plurality of ribs (225) are disposed within the cooling passage (226) or outside the cooling passage (226). In addition, the plurality of ribs (225) are formed within a weight reduction cavity. A gas turbine (100) and a manufacturing method of a sealing cover (20) are also provided. The sealing cover (20) helps to improve working performance of the gas turbine (100).
摘要翻译：用于燃气轮机（100）的密封盖（20）。燃气涡轮机（100）包括至少一个涡轮盘（143），并且密封盖（20）用于覆盖涡轮盘（143）。密封盖（20）的侧壁（22a）设有第一气孔（222）和第二气孔（223）。在第一气孔（222）和第二气孔（223）之间形成间隔。冷却通道（226）和多个肋（225）设置在密封盖（20）内。冷却通路226与第一空气孔222及第二空气孔223连通，多个肋225配置在冷却通路226内或冷却通路226的外部）。另外，多个肋（225）形成在减重腔内。还提供了燃气轮机（100）和密封盖（20）的制造方法。密封盖（20）有助于提高燃气轮机（100）的工作性能。

7. 发明申请

WO2011100483A1 SALIVARY BIOMARKERS FOR LUNG CANCER DETECTION 审中-公开
标题翻译：用于肺癌检测的SALIVARY生物标志物
公开(公告)号：WO2011100483A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/024415
申请日：2011-02-10
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , WONG, David, T. , ZHANG, Lei , XIAO, Hua , ZHOU, Hui
发明人： WONG, David, T. , ZHANG, Lei , XIAO, Hua , ZHOU, Hui
IPC分类号： C12Q1/68 , G01N33/574 , G01N33/487
CPC分类号： C12Q1/6886 , C12Q1/686 , C12Q1/6872 , C12Q1/689 , C12Q2600/158 , G01N33/487 , G01N33/57423
摘要： Presented herein are biomarkers related to lung cancer. The presently identified salivary biomarkers (CCNI, EGFR, FGF9, GREB 1 protein, LZTS, BRAF, FRS2, ANXA 1, Haptoglobin Hp2, Zinc Alpha2-Glycoprotein, Calprotectin, Porphyromonas catoniae 16S rRNA, Campylobacter showae 16S rRNA, Stre'ptocococcus salivaris 16S rRNA, Campylobacter rectus 16S rRNA, Veillonella parvula 16S rRNA, Kigella oralis 16S rRNA, and Granulicatella adiacens 16S rRNA) create the basis for a lung cancer detection bioassay with sensitivity and specificity. Means and methods for evaluating the data generated using multiple biomarkers in order to validate findings and further use of the multiplexed lung cancer assay in clinical, diagnostic and therapeutic uses is also included.
摘要翻译：本文提供了与肺癌相关的生物标志物。目前鉴定的唾液生物标志物（CCNI，EGFR，FGF9，GREB 1蛋白，LZTS，BRAF，FRS2，ANXA1，Haptoglobin Hp2，锌Alpha2-糖蛋白，Calprotectin，卟啉单核菌属16S rRNA，弯曲杆菌16S rRNA，唾液球菌16S rRNA，直肠弯曲杆菌16S rRNA，Veleonella parvula 16S rRNA，口蹄疫16S rRNA和Granulicatella adiacens 16S rRNA）为敏感性和特异性的肺癌检测生物测定奠定了基础。还包括用于评估使用多种生物标志物产生的数据以便在临床，诊断和治疗用途中验证多发性肺癌测定的发现和进一步使用的方法和方法。

8. 发明申请

WO2011100472A1 SALIVARY TRANSCRIPTOMIC AND PROTEOMIC BIOMARKERS FOR BREAST CANCER DETECTION 审中-公开
标题翻译：用于乳腺癌检测的阴性转录和保护性生物标志物
公开(公告)号：WO2011100472A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/024401
申请日：2011-02-10
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , WONG, David, T. , ZHANG, Lei , XIAO, Hua , ZHOU, Hui
发明人： WONG, David, T. , ZHANG, Lei , XIAO, Hua , ZHOU, Hui
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/57415 , C12Q1/6886 , C12Q2600/158
摘要： Presented herein are biomarkers related to breast cancer. The presently identified salivary biomarkers create the basis for a breast cancer detection bioassay with sensitivity and specificity. Means and methods for evaluating the data generated using multiple biomarkers in order to validate findings and further use of the multiplexed breast cancer assay in clinical, diagnostic and therapeutic uses is also included.
摘要翻译：本文提供的是与乳腺癌相关的生物标志物。目前鉴定的唾液生物标志物为敏感性和特异性的乳腺癌检测生物测定奠定了基础。还包括用于评估使用多种生物标志物产生的数据以便验证临床，诊断和治疗用途中的多发性乳腺癌测定的发现和进一步使用的方法和方法。

9. 发明申请

WO9822860A3 COMPUTER AIDED INSPECTION MACHINE 审中-公开
标题翻译：计算机辅助检测机
公开(公告)号：WO9822860A3
公开(公告)日：2000-08-24
申请号：PCT/US9720431
申请日：1997-11-07
申请人： BUCKLEY B SHAWN , CHEN JIHONG , YANG DAO SHAN , ZHOU HUI CHENG
发明人： BUCKLEY B SHAWN , CHEN JIHONG , YANG DAO SHAN , ZHOU HUI CHENG
IPC分类号： G01B11/02 , G01B11/24
CPC分类号： G01B11/024
摘要： An automatic inspection method and apparatus using structured light (3) and machine vision cameras (2) to inspect an object (4) in conjunction with the geometric model of the object (4) is disclosed. Camera images of the object (4) are analyzed by computer to produce the location of points on the object's surface in three dimensions. During a setup phase before object inspection, the points are analyzed with respect to the geometric model computer file of the object (4). Many points are eliminated to reduce data-taking and analysis time to a minimum and to prevent extraneous reflections from producing errors. When similar objects are subsequently inspected, points from each surface of interest are spatially averaged to give high accuracy measurements of object (4) dimensions. The inspection device uses several multiplexed sensors, each composed of a camera (2) and a structured light source (3), to measure all sides of the object (4) on a single pass. Calibration and compensation methods are also disclosed.
摘要翻译：公开了一种使用结构光（3）和机器视觉摄像机（2）与物体（4）的几何模型一起检查物体（4）的自动检查方法和装置。计算机对物体（4）的相机图像进行分析，以在三维上产生物体表面上的点的位置。在对象检查之前的设置阶段，对对象（4）的几何模型计算机文件进行分析。消除了许多观点，将数据采集和分析时间降至最低，并防止外部反射产生错误。当随后检查相似的物体时，来自每个感兴趣表面的点在空间上被平均以给出物体（4）尺寸的高精度测量。检查装置使用由摄像机（2）和结构化光源（3）组成的多个多路复用传感器，以一次通过测量物体（4）的所有侧面。还公开了校准和补偿方法。

10. 发明申请

WO2012178036A3 INHIBITORS OF RTT109 AS ANTI-FUNGAL AGENTS 审中-公开
标题翻译： RTT109作为抗真菌药物的抑制剂
公开(公告)号：WO2012178036A3
公开(公告)日：2013-04-18
申请号：PCT/US2012043785
申请日：2012-06-22
申请人： MAYO FOUNDATION , UNIV MINNESOTA , ZHANG ZHIGUO , LIMPER ANDREW H , HAN JUNHONG , ZHOU HUI , KOTTOM THEODORE J , HOOK DEREK , BERMAN JUDITH , WALTERS MICHAEL ANTHONY
发明人： ZHANG ZHIGUO , LIMPER ANDREW H , HAN JUNHONG , ZHOU HUI , KOTTOM THEODORE J , HOOK DEREK , BERMAN JUDITH , WALTERS MICHAEL ANTHONY
IPC分类号： A61K31/095 , A61K31/433 , A61K31/517 , A61P31/00 , A61P31/04
CPC分类号： C12Q1/18 , A61K31/18 , A61K31/433 , A61K31/517 , G01N2333/38 , G01N2333/91045
摘要： This document relates to materials and methods for identifying chemical inhibitors of fungal targets useful for treating organisms infected with opportunistic fungal pathogens. For example, this document provides the materials and methods for identifying and optimizing chemical inhibitors of Rtt109, a fungal histone acetyltransferase. This document also provides the materials and methods for using high throughput screening technologies to identify candidate chemical inhibitors of Rtt109 as well as the materials and methods for evaluating candidate chemical inhibitors of Rtt109 in secondary screens for their binding efficacy, molecular specificity, and cellular toxicity.
摘要翻译：本文件涉及用于鉴定用于治疗感染机会性真菌病原体的生物体的真菌靶标的化学抑制剂的材料和方法。例如，本文件提供了鉴定和优化Rtt109（一种真菌组蛋白乙酰转移酶）化学抑制剂的材料和方法。本文件还提供了使用高通量筛选技术鉴定Rtt109候选化学抑制剂的材料和方法，以及用于评估二级筛选候选化学抑制剂Rtt109的结合效力，分子特异性和细胞毒性的材料和方法。

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