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1. 发明申请

WO2005072082A3 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF 审中-公开
标题翻译： 2-胍基二咪唑啉化合物及其制备和使用方法
公开(公告)号：WO2005072082A3
公开(公告)日：2005-12-22
申请号：PCT/US2004038909
申请日：2004-11-19
申请人： US ARMY MED RES MAT COMMAND , LIN AI J , ZHANG QUAN , GUAN JIAN , MILHOUS WILBUR K
发明人： LIN AI J , ZHANG QUAN , GUAN JIAN , MILHOUS WILBUR K
IPC分类号： A61K31/4168 , A61K31/4178 , C07D233/44 , C07D233/54 , C07D405/12
CPC分类号： C07D233/96 , C07D233/54 , C07D405/12
摘要： Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural Formula A or B wherein R 1 and R 2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R 3 is an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.
摘要翻译：本文公开了具有结构式A或B的2-胍基咪唑烷二酮化合物，其中R 1和R 2各自独立地为氢，卤素，烷基，烷氧基，氨基，烷基氨基或芳烷基，其中R 3是烷基，环烷基，杂环烷基，酰基，芳基，杂芳基，烷基芳基，磺酰基，烷基磺酰基及其药学上可接受的盐，及其制备方法。还公开了用2-胍基咪唑烷二酮化合物治疗，预防或抑制疟疾的方法，以及包含2-胍基脒基咪唑烷二酮化合物的药物组合物和试剂盒。

2. 发明申请

WO2005072082A2 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF 审中-公开
标题翻译： 2-胍基二咪唑啉化合物及其制备和使用方法
公开(公告)号：WO2005072082A2
公开(公告)日：2005-08-11
申请号：PCT/US2004/038909
申请日：2004-11-19
申请人： U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND , LIN, Ai J. , ZHANG, Quan , GUAN, Jian , MILHOUS, Wilbur K.
发明人： LIN, Ai J. , ZHANG, Quan , GUAN, Jian , MILHOUS, Wilbur K.
IPC分类号： A61K31/4168 , A61K31/4178 , C07D233/44 , C07D233/54 , C07D405/12
CPC分类号： C07D233/96 , C07D233/54 , C07D405/12
摘要： Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural Formula A or B wherein R 1 and R 2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R 3 is an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.
摘要翻译：本文公开了具有结构式A或B的2-胍基咪唑烷二酮化合物，其中R 1和R 2各自独立地为氢，卤素，烷基，烷氧基，氨基，烷基氨基或芳烷基，并且其中R 3为烷基，环烷基，杂环烷基，酰基，芳基，杂芳基，烷基芳基，磺酰基，烷基磺酰基及其药学上可接受的盐及其制备方法。还公开了用2-胍基咪唑烷二酮化合物治疗，预防或抑制疟疾的方法，以及包含2-胍基脒基咪唑烷二酮化合物的药物组合物和试剂盒。

3. 发明申请

WO2007018921A3 ELECTRO-OPTICAL SYSTEM, APARATUS, AND METHOD FOR AMBULATORY MONITORING 审中-公开
标题翻译：电光系统，APARATUS和用于健康监测的方法
公开(公告)号：WO2007018921A3
公开(公告)日：2007-06-07
申请号：PCT/US2006026963
申请日：2006-07-12
申请人： GEN HOSPITAL CORP , ZHANG QUAN , STRANGMAN GARY
发明人： ZHANG QUAN , STRANGMAN GARY
IPC分类号： A61B5/00
CPC分类号： A61B5/02438 , A61B5/0002 , A61B5/0059 , A61B5/1455 , A61B5/4094 , A61B5/4509 , A61B5/7232 , G06F19/12 , G06F19/26
摘要： An electro-optical system, apparatus, and method allow long-term, ambulatory measurements to be made on a patient using light transmitted into the patient and resulting light received from the patient.
摘要翻译：电光学系统，装置和方法允许使用透射到患者中的光并从患者接收到的所得光来对患者进行长期的，动态的测量。

4. 发明申请

WO2007018921A2 ELECTRO-OPTICAL SYSTEM, APARATUS, AND METHOD FOR AMBULATORY MONITORING 审中-公开
标题翻译：电光系统，蜂窝电话和用于监测监测的方法
公开(公告)号：WO2007018921A2
公开(公告)日：2007-02-15
申请号：PCT/US2006/026963
申请日：2006-07-12
申请人： THE GENERAL HOSPITAL CORPORATION , ZHANG, Quan , STRANGMAN, Gary
发明人： ZHANG, Quan , STRANGMAN, Gary
IPC分类号： A61B5/00
CPC分类号： A61B5/02438 , A61B5/0002 , A61B5/0059 , A61B5/1455 , A61B5/4094 , A61B5/4509 , A61B5/7232 , G06F19/12 , G06F19/26
摘要： An electro-optical system, apparatus, and method allow long-term, ambulatory measurements to be made on a patient using light transmitted into the patient and resulting light received from the patient.
摘要翻译：光电系统，设备和方法允许使用透射到患者体内的光和从患者接收的光产生对患者的长期动态测量。

5. 发明申请

WO2005072082B1 2-guanidinylimidazolidinedione compounds and methods of making and using thereof 审中-公开
标题翻译： 2-胍基咪唑烷二酮化合物及其制备和使用方法
公开(公告)号：WO2005072082B1
公开(公告)日：2006-05-11
申请号：PCT/US2004038909
申请日：2004-11-19
申请人： LIN AI J , ZHANG QUAN , GUAN JIAN , MILHOUS WILBUR K , US ARMY MED RES MAT COMMAND
发明人： LIN AI J , ZHANG QUAN , GUAN JIAN , MILHOUS WILBUR K
IPC分类号： A61K31/4168 , A61K31/4178 , C07D233/44 , C07D233/54 , C07D405/12
CPC分类号： C07D233/96 , C07D233/54 , C07D405/12
摘要： Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural Formula A or B wherein R 1 and R 2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R 3 is an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.
摘要翻译：本文公开了具有结构式A或B的2-胍基咪唑烷二酮化合物，其中R 1和R 2各自独立地为氢，卤素，烷基，烷氧基，氨基，烷基氨基或芳烷基，其中R 3是烷基，环烷基，杂环烷基，酰基，芳基，杂芳基，烷基芳基，磺酰基，烷基磺酰基及其药学上可接受的盐，及其制备方法。还公开了用2-胍基咪唑烷二酮化合物治疗，预防或抑制疟疾的方法，以及包含2-胍基脒基咪唑烷二酮化合物的药物组合物和试剂盒。

6. 发明申请

WO2014210131A1 SYSTEM AND METHOD FOR NON-INVASIVE, INTRACRANIAL BRIAN MOTION MONITORING 审中-公开
标题翻译：非侵入式，简单的BRIAN运动监测的系统和方法
公开(公告)号：WO2014210131A1
公开(公告)日：2014-12-31
申请号：PCT/US2014/044056
申请日：2014-06-25
申请人： THE GENERAL HOSPITAL CORPORATION , ZHANG, Quan , STRANGMAN, Gary
发明人： ZHANG, Quan , STRANGMAN, Gary
IPC分类号： A61B5/11
CPC分类号： A61B5/4064 , A61B5/0075 , A61B5/14553 , A61B5/6814
摘要： A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal.
摘要翻译：提供了一种系统和方法，用于评估包括一个或多个表面生物层和靶向生物层的受试者的生物组织的运动。在一个或多个表面生物层内引入光学扰动，但不在目标生物层内。在光学扰动之前，期间或之后获取一组光信号数据，并且使用该组光信号数据，确定代表穿过生物层的光的一组光学特性。使用一组光学特性和生物层的模型，分离与目标生物层一致的目标光信号，并使用目标光信号确定所需生物组织的移动。

7. 发明申请

WO2015066445A1 SYSTEM FOR MEASURING AND MONITORING BLOOD PRESSURE 审中-公开
标题翻译：测量和监测血压的系统
公开(公告)号：WO2015066445A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063374
申请日：2014-10-31
申请人： THE GENERAL HOSPITAL CORPORATION , ZHANG, Quan , ZHANG, Yuanting
发明人： ZHANG, Quan , ZHANG, Yuanting
IPC分类号： A61B5/02 , A61B5/0285 , A61B5/021
CPC分类号： A61B5/6803 , A61B5/0002 , A61B5/0022 , A61B5/02055 , A61B5/02108 , A61B5/02125 , A61B5/022 , A61B5/02416 , A61B5/0245 , A61B5/026 , A61B5/0261 , A61B5/0402 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2560/0223 , A61B2562/0247 , A61B2562/04 , A61B2562/046 , A61B2562/12 , A61B2562/164
摘要： A system and method for measuring and monitoring blood pressure is provided. The system includes a wearable device and a tonometry device coupled to the wearable device. The Tonometry device is configured to compress a superficial temporal artery (STA] of a user. A sensor pad is attached to the wearable device adjacent the tonometry device. A blood pressure sensor is integrated within the sensor pad for continuous, unobtrusive blood pressure monitoring.
摘要翻译：提供了一种用于测量和监测血压的系统和方法。该系统包括可佩戴装置和耦合到可穿戴装置的眼压测量装置。眼压测量装置被配置为压缩使用者的浅表性颞动脉（STA），传感器垫附着在眼压测量装置附近的可穿戴装置上。血压传感器集成在传感器垫内，用于连续，不引人注意的血压监测。

8. 发明申请

WO2011144109A3 METHOD FOR CHECKING SERVICE RULES OF NETWORK ELEMENT CONFIGURATION AND CHECKING SYSTEM 审中-公开
标题翻译：检查网络元素配置和检查系统的服务规则的方法
公开(公告)号：WO2011144109A3
公开(公告)日：2012-04-26
申请号：PCT/CN2011074784
申请日：2011-05-27
申请人： HUAWEI TECH CO LTD , ZHANG QUAN , XIE NING
发明人： ZHANG QUAN , XIE NING
IPC分类号： H04W24/04 , G06F9/44 , H04L12/24
CPC分类号： H04L41/0869
摘要： A method for checking service rules of network element configuration and a checking system are disclosed. The method for checking service rules of network element configuration includes following steps: receiving a first indication, which is used to indicate a service rules type selected by users, from a customized interface for checking rules; receiving a second indication, which is used to indicate an attribute set to be checked in Managed Object Class (MOC) selected by users, from the customized interface for checking rules; receiving a third indication, which is used to indicate a sifting condition assigned by users, from the customized interface for checking rules, wherein the sifting condition is used to sift the Managed Object Instance (MOI) corresponding to the MOC to be checked; generating a configuration checking script based on the first indication, the second indication and the third indication; checking the service rules of network element configuration by calling the configuration checking script. The solutions of the embodiments of the invention are beneficial to relatively reduce the maintenance costs for implementing the service of checking the service rules of network element configuration.
摘要翻译：公开了一种检查网元配置服务规则和检查系统的方法。检查网元配置服务规则的方法包括以下步骤：从用于检查规则的定制接口接收用于指示用户选择的服务规则类型的第一指示; 从用于检查规则的定制接口接收用于指示由用户选择的管理对象类（MOC）中检查的属性集的第二指示; 从用于检查规则的定制界面接收用于指示用户分配的筛选条件的第三指示，其中筛选条件用于筛选对应于要检查的MOC的管理对象实例（MOI）; 基于所述第一指示，所述第二指示和所述第三指示来生成配置检查脚本; 通过调用配置检查脚本检查网元配置的业务规则。本发明的实施例的解决方案有利于相对降低用于实现检查网元配置的服务规则的服务的维护成本。

9. 发明申请

WO2007018921A4 ELECTRO-OPTICAL SYSTEM, APARATUS, AND METHOD FOR AMBULATORY MONITORING 审中-公开
标题翻译：电光系统，APARATUS和用于健康监测的方法
公开(公告)号：WO2007018921A4
公开(公告)日：2010-09-30
申请号：PCT/US2006026963
申请日：2006-07-12
申请人： GEN HOSPITAL CORP , ZHANG QUAN , STRANGMAN GARY
发明人： ZHANG QUAN , STRANGMAN GARY
IPC分类号： A61B5/00
CPC分类号： A61B5/02438 , A61B5/0002 , A61B5/0059 , A61B5/1455 , A61B5/4094 , A61B5/4509 , A61B5/7232 , G06F19/12 , G06F19/26
摘要： An electro-optical system, apparatus, and method allow long-term, ambulatory measurements to be made on a patient using light transmitted into the patient and resulting light received from the patient.
摘要翻译：电光学系统，装置和方法允许使用透射到患者中的光并从患者接收到的所得光来对患者进行长期的，动态的测量。

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