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1. 发明申请

WO2021155345A1 VEHICLE AUTO-CHARGING SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2021155345A1
公开(公告)日：2021-08-05
申请号：PCT/US2021/016010
申请日：2021-02-01
申请人： SEEGRID CORPORATION , BUTINA, Edward , COLE, Justin , SEAL, Jacob , THOMPSON, Bruce , ZHANG, Chun , YAUTZ, Dustin , WEISS, Mitchell
发明人： BUTINA, Edward , COLE, Justin , SEAL, Jacob , THOMPSON, Bruce , ZHANG, Chun , YAUTZ, Dustin , WEISS, Mitchell
IPC分类号： B60L15/32 , G06Q50/06 , H02J7/00
摘要： A vehicle charging system comprises at least one controller and at least one arm, each arm having a first end coupled an actuator and a second end comprising a charging interface. The actuator is configured to articulate the arm into a charging position. The charging interface comprises at least one charging contact coupled to a power source and configured to engage and deliver power to a vehicle charging interface to charge at least one battery of a vehicle. The charging system can include a plurality of arms, each configured to charge a different vehicle. A method of charging one or more vehicles using the charging system is also provided.

2. 发明申请

WO2015009616A1 PIPERIDINYL INDOLE DERIVATIVES AND THEIR USE AS COMPLEMENT FACTOR B INHIBITORS 审中-公开
标题翻译：哌啶吲哚衍生物及其作为补体因子B抑制剂的用途
公开(公告)号：WO2015009616A1
公开(公告)日：2015-01-22
申请号：PCT/US2014/046515
申请日：2014-07-14
申请人： NOVARTIS AG , ADAMS, Christopher , CAPPARELLI, Michael Paul , EHARA, Takeru , KARKI, Rajeshri Ganesh , MAINOLFI, Nello , ZHANG, Chun
发明人： ADAMS, Christopher , CAPPARELLI, Michael Paul , EHARA, Takeru , KARKI, Rajeshri Ganesh , MAINOLFI, Nello , ZHANG, Chun
IPC分类号： C07D401/14 , C07D413/14 , C07D401/06 , C07D403/06 , C07D417/14 , A61K31/454 , A61K31/4545 , A61K31/5377 , A61P27/00 , A61P37/00
CPC分类号： C07D413/06 , A61K31/404 , A61K31/438 , A61K31/4439 , A61K31/454 , A61K31/5377 , A61K31/55 , C07D401/06 , C07D401/14 , C07D403/06 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitors of the complement alternative pathway, in particular of Factor B. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译：本发明提供式I化合物：（I）制备本发明化合物的方法及其作为补体替代途径抑制剂，特别是因子B的治疗用途。本发明进一步提供了药理学上的组合活性剂和药物组合物。

3. 发明申请

WO2014143638A1 2-(1H-INDOL-4-YLMETHYL)-3H-IMIDAZO[4,5-B]PYRIDINE-6-CARBONITRILE DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS USEFUL FOR THE TREATMENT OF OPHTHALMIC DISEASES 审中-公开
标题翻译： 2-（1H-吲哚-4-基甲基）-3H-咪唑并[4,5-B]吡啶-6-羰基衍生物作为用于治疗眼病的补充因子B抑制剂
公开(公告)号：WO2014143638A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/026875
申请日：2014-03-13
申请人： NOVARTIS AG , ADAMS, Christopher Michael , BABU, Charles , CAPPARELLI, Michael Paul , DING, Jian , EHARA, Takeru , JENDZA, Keith , JI, Nan , KARKI, Rajeshri Ganesh , KAWANAMI, Toshio , MAINOLFI, Nello , POWERS, James J. , SERRANO-WU, Michael H. , XUE, Liang , ZHANG, Chun
发明人： ADAMS, Christopher Michael , BABU, Charles , CAPPARELLI, Michael Paul , DING, Jian , EHARA, Takeru , JENDZA, Keith , JI, Nan , KARKI, Rajeshri Ganesh , KAWANAMI, Toshio , MAINOLFI, Nello , POWERS, James J. , SERRANO-WU, Michael H. , XUE, Liang , ZHANG, Chun
IPC分类号： C07D471/04 , A61K31/437 , A61P27/02
CPC分类号： C07D471/04
摘要： The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents.
摘要翻译：本发明提供式（I）化合物：其中X为N或CH，Y为NH，O或S，制备这些化合物的方法及其作为因子B抑制剂用于治疗与补体相关的病症和疾病的用途替代途径激活如年龄相关性黄斑变性，糖尿病性视网膜病变和相关眼科疾病。本发明还提供药物组合物和药理活性剂的组合。

4. 发明申请

WO2007098638A8 A POWER EXTERNAL CIRCULATION ESTERING REACTOR 审中-公开
标题翻译：电力外部循环反应器
公开(公告)号：WO2007098638A8
公开(公告)日：2008-01-24
申请号：PCT/CN2006000291
申请日：2006-02-28
申请人： CHINA TEXTILE IND ENGINEERING , LUO WENDE , ZHOU HUATANG , ZHOU QIGUI , ZHANG CHUN , WAN WANGSHENG , XU HAODONG
发明人： LUO WENDE , ZHOU HUATANG , ZHOU QIGUI , ZHANG CHUN , WAN WANGSHENG , XU HAODONG
IPC分类号： B01J19/00 , B01J10/00 , C08G63/00
CPC分类号： C08G63/785 , B01J19/006 , B01J19/0066 , B01J19/1837 , B01J19/1881 , B01J2219/00081 , B01J2219/00083 , B01J2219/0009 , B01J2219/00092 , B01J2219/00768 , B01J2219/00777 , B01J2219/185 , B01J2219/1943
摘要： A power external circulation estering reactor comprises a heating reaction device, a evaporating reaction device, a power external impelling device, wherein the heating reaction device includes a vertical type coiler heating reactor whose exit and inlet connect with the evaporating reaction device and power external impelling device respectively, the evaporating reaction device includes a reaction container with a gas exit at the top. The upper part and lower part of the reaction container are upper evaporation zone and lower reaction zone respectively. The bottom of the reaction container connects with the power external impelling device that is mechanical and locates at the exterior of the evaporating reaction device.
摘要翻译：电力外循环酯化反应器包括加热反应装置，蒸发反应装置，电力外部推动装置，其中加热反应装置包括垂直式卷取机加热反应器，其出口和入口与蒸发反应装置连接并且供电外部推进装置蒸发反应装置包括在顶部具有气体出口的反应容器。反应容器的上部和下部分别为上蒸发区和下反应区。反应容器的底部与机械的动力外部推进装置连接，位于蒸发反应装置的外部。

5. 发明申请

WO2005095455A1 ANTIBODY SPECIFIC FOR PARAFIBROMIN, A NEW MARKER OF PARATHYROID CARCINOMA 审中-公开
标题翻译： PARAFIBROMIN的抗体特异性，一种新的标记物
公开(公告)号：WO2005095455A1
公开(公告)日：2005-10-13
申请号：PCT/US2005/010442
申请日：2005-03-28
申请人： VAN ANDEL RESEARCH INSTITUE , TEH, Bin Tian , TAN, Min-Han , CAO, Boliang , RESAU, James, H. , ZHAO, Ping , ZHANG, Chun
发明人： TEH, Bin Tian , TAN, Min-Han , CAO, Boliang , RESAU, James, H. , ZHAO, Ping , ZHANG, Chun
IPC分类号： C07K16/00
CPC分类号： G01N33/57407 , C07K16/18 , G01N33/57438
摘要： Expression of the HRPT2 gene, which encodes parafibromin, is reduced in parathyroid carcinoma as well as in other carcinomas. Antibodies specific for parafibromin are disclosed, along with their use to evaluate levels of parafibromin in tissue samples. Loss of immunoreactivity is a highly selective marker for parathyroid carcinoma, and is a useful marker for kidney and bladder cancer, as well as other carcinomas, and provides the first laboratory test that can serve as a standard for pathological diagnosis of parathyroid cancer.
摘要翻译：编码parafibromin的HRPT2基因的表达在甲状旁腺癌以及其他癌中减少。公开了对抗副纤维蛋白的特异性抗体，以及它们用于评估组织样品中副原纤维素水平的用途。免疫反应性的丧失是甲状旁腺癌的高度选择性标记物，并且是肾和膀胱癌以及其他癌症的有用标志物，并提供可作为甲状旁腺癌病理诊断标准的第一个实验室检查。

6. 发明申请

WO2015066241A1 2-BENZYL-BENZIMIDAZOLE COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF 审中-公开
标题翻译： 2-苄基 - 苯并咪唑补体因子B抑制剂及其用途
公开(公告)号：WO2015066241A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063009
申请日：2014-10-29
申请人： NOVARTIS AG , ADAMS, Christopher , EHARA, Takeru , JENDZA, Keith , JI, Nan , KAWANAMI, Toshio , MAINOLFI, Nello , POWERS, James J. , SERRANO-WU, Michael , ZHANG, Chun
发明人： ADAMS, Christopher , EHARA, Takeru , JENDZA, Keith , JI, Nan , KAWANAMI, Toshio , MAINOLFI, Nello , POWERS, James J. , SERRANO-WU, Michael , ZHANG, Chun
IPC分类号： C07D235/12 , A61K31/4184 , C07D235/14 , A61P27/02
CPC分类号： C07D235/12 , A61K31/4184 , A61K45/06 , C07D235/14 , A61K2300/00
摘要： The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译：本发明提供式（I）化合物，其用于制备本发明化合物的方法及其治疗用途。本发明还提供药理活性剂和药物组合物的组合。

7. 发明申请

WO2022257095A1 CURABLE SILICONE RUBBER COMPOSITIONS 审中-公开
公开(公告)号：WO2022257095A1
公开(公告)日：2022-12-15
申请号：PCT/CN2021/099606
申请日：2021-06-11
申请人： DOW SILICONES CORPORATION , CHEN, Yusheng , SU, Fengyi , WANG, Rui , WANG, Peng , GUO, Yi , ZHANG, Chun Ming
发明人： CHEN, Yusheng , SU, Fengyi , WANG, Rui , WANG, Peng , GUO, Yi , ZHANG, Chun Ming
IPC分类号： C08L83/07 , C08L83/05 , C09J183/07 , C09J11/06 , C09J11/04 , C09J7/00 , C09J7/30 , C09K3/10 , C08K5/101
摘要： This disclosure relates to curable silicone rubber compositions suitable for use in the manufacture of cured-in-place gaskets (CIPGs), silicone elastomers resulting from the cure of said compositions and methods for making cured-in-place gaskets from said curable silicone rubber compositions. The inclusion of a compound having at least two trialkoxysilyl groups, at least two dialkoxyalkylsilyl groups or a mixture of two or more trialkoxysilyl groups, and dialkoxyalkylsilyl groups per molecule selected from: (i) (R 10) z (R 11) 3-z Si- (W) -Si (R 11) 3-z (R 10) z where each R 11 is the same or different and is an alkoxy group having 1 to 6 carbons; each R 10 is the same or different and is R 11 or an alkyl group having 1 to 6 carbons, z is 0 or 1 and W is a linear or branched alkylene having 1 to 12 carbons; or (ii) 1, 3, 5-tris [3- ( (R 10) z (R 11) 3-z Si) -D] -1, 3, 5-triazine-2, 4, 6 (1H, 3H, 5H) -trione wherein R 11, R 10 and z are as defined above and D is an alkylene group having from 1 to 6 carbons; provides CIPGs which show both a good adhesion to aluminium and a good compression set.

8. 发明申请

WO2022072616A1 VEHICLE OBJECT-ENGAGEMENT SCANNING SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2022072616A1
公开(公告)日：2022-04-07
申请号：PCT/US2021/052853
申请日：2021-09-30
申请人： SEEGRID CORPORATION , ZHANG, Chun , GRECO, Nathan , GRUSKY, Adam , THOMPSON, Bruce , BUTINA, Ed , SEAL, Jacob , HARROLD II, John , YOUNG, Ryan , SCHMIDT, Benjamin , TRACY, Andrew
发明人： ZHANG, Chun , GRECO, Nathan , GRUSKY, Adam , THOMPSON, Bruce , BUTINA, Ed , SEAL, Jacob , HARROLD II, John , YOUNG, Ryan , SCHMIDT, Benjamin , TRACY, Andrew
IPC分类号： B66F9/06 , B66F9/18 , G01V3/02 , G06F7/00
摘要： A transport vehicle, such as a vision guided vehicle, can comprise a drive portion constructed to facilitate movement of the transport vehicle and a load portion constructed to engage an object of interest. The load portion can comprise an object engagement apparatus and at least one sensor coupled to or disposed within a distal end of the object engagement apparatus, wherein the sensor can be at least a 2D sensor. The engagement apparatus can comprise forks, at least one fork having sensor coupled to or disposed within a fork tip. The 2D sensor can comprise a scanning LIDAR sensor arranged to collect information to identify a pickable pallet, for example.

9. 发明申请

WO2011020319A8 FUSION PROTEIN REGULATING PLASMA GLUCOSE AND LIPID, ITS PREPARATION METHOD AND USE 审中-公开
标题翻译：融合蛋白调节等离子体葡萄糖和脂质，其制备方法和用途
公开(公告)号：WO2011020319A8
公开(公告)日：2012-03-15
申请号：PCT/CN2010071026
申请日：2010-03-12
申请人： CHONGQING FAGEN BIOMEDICAL INC , FAN KAI , ZHAO ZHIQUAN , ZHANG CHUN , CHEN YONG , LUO HUA , YANG LI , LIU HONGHONG
发明人： FAN KAI , ZHAO ZHIQUAN , ZHANG CHUN , CHEN YONG , LUO HUA , YANG LI , LIU HONGHONG
IPC分类号： C12N15/06 , A61K38/26 , A61P3/04 , A61P3/06 , A61P3/10 , C07K14/50 , C07K14/605 , C12N15/63
CPC分类号： C07K14/43 , A61K38/00 , C07K14/50 , C07K14/605 , C07K2319/00
摘要： Provided is a fusion protein, which comprises human fibroblast growth factor 21 and glucagon-like-peptide-1 or its analogs. Also provided is the medicament composition comprising the fusion protein, which can be used for treating or preventing obesity, diabetes, hyperglycemia and hyperlipidemia etc.
摘要翻译：提供了一种融合蛋白，其包含人成纤维细胞生长因子21和胰高血糖素样肽-1或其类似物。还提供了包含融合蛋白的药物组合物，其可用于治疗或预防肥胖症，糖尿病，高血糖症和高脂血症等。

10. 发明申请

WO2011076124A1 RAPID RESPONSE RELATIVE HUMIDITY SENSOR USING ANODIC ALUMINUM OXIDE FILM 审中-公开
标题翻译：使用阳极氧化铝膜快速响应相对湿度传感器
公开(公告)号：WO2011076124A1
公开(公告)日：2011-06-30
申请号：PCT/CN2010/080145
申请日：2010-12-22
申请人： NANO AND ADVANCED MATERIALS INSTITUTE LIMITED , ZHANG, Chun , MIAO, Jianying , WANG, Ning
发明人： ZHANG, Chun , MIAO, Jianying , WANG, Ning
IPC分类号： G01N27/22
CPC分类号： G01N27/223
摘要： A rapid response relative humidity sensor based on nano-structured aluminum oxide thin film is disclosed. The main body of the sensor is an anodic aluminum oxide thin film of about 2-20 μm thick formed from an Al substrate which serves as one electrode. A porous metal layer of about 20-200 nm thick is formed over the anodic aluminum oxide thin film and functions as a second electrode. The alumina thin film contains nano-sized channels of about 10-100 nm in diameter, serving as a capacitive relative humidity sensor having high sensitivity and short response time. Thermal annealing at elevated temperature improves the linearity of the capacitance versus humidity curve, giving a full range humidity sensing range. Hysteresis and degradation are negligible for the humidity sensors.
摘要翻译：公开了一种基于纳米结构氧化铝薄膜的快速响应相对湿度传感器。传感器的主体是由作为一个电极的Al衬底形成的大约2-20μm厚的阳极氧化铝薄膜。在阳极氧化铝薄膜上形成约20-200nm厚的多孔金属层，起第二电极的作用。氧化铝薄膜包含直径约10-100nm的纳米尺寸的通道，用作具有高灵敏度和较短响应时间的电容式相对湿度传感器。高温下的热退火可提高电容与湿度曲线的线性度，从而提供全范围湿度检测范围。湿度传感器的滞后和退化可忽略不计。

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