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1. 发明申请

WO2012055998A1 USE OF MONASCUS IN ORGANIC ACID PRODUCTION 审中-公开
标题翻译： MONASCUS在有机酸生产中的应用
公开(公告)号：WO2012055998A1
公开(公告)日：2012-05-03
申请号：PCT/EP2011/068971
申请日：2011-10-28
申请人： TOTAL S.A. , WEUSTHUIS, Ruud Alexander , WOLBERT, Emil Johan Harald , SPRINGER, Jan , VAN DER OOST, John , EGGINK, Gerrit
发明人： WEUSTHUIS, Ruud Alexander , WOLBERT, Emil Johan Harald , SPRINGER, Jan , VAN DER OOST, John , EGGINK, Gerrit
IPC分类号： C12N1/14 , C12R1/645
CPC分类号： C12P7/40 , C12N9/0006 , C12P7/46 , C12P7/56 , C12P7/625 , C12R1/645 , C12Y101/01027
摘要： The present invention provides tools and methods for producing organic acids using strains of Monascus which are tolerant to high organic acid concentrations at low pH.
摘要翻译：本发明提供使用耐低温pH值的高有机酸浓度的红曲霉菌株生产有机酸的工具和方法。

2. 发明申请

WO2009070022A1 PRODUCTION OF A PRODUCT IN A MICROBIAL FUEL CELL 审中-公开
标题翻译：在微生物燃料电池中生产产品
公开(公告)号：WO2009070022A1
公开(公告)日：2009-06-04
申请号：PCT/NL2008/050754
申请日：2008-11-27
申请人： STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK , WEUSTHUIS, Ruud Alexander , HAMELERS, Hubertus Victor Marie
发明人： WEUSTHUIS, Ruud Alexander , HAMELERS, Hubertus Victor Marie
IPC分类号： H01M8/16 , H01M4/90 , H01M8/10
CPC分类号： H01M8/16 , H01M4/90 , H01M2008/1095 , Y02E60/527 , Y02P70/56
摘要： The invention relates to a specific use of a microbial fuel cell for fermenting a substrate into a product, wherein said product is oxidised compared to the substrate present in the microbial fuel cell and wherein electrical energy i s produced.
摘要翻译：本发明涉及用于将底物发酵成产品的微生物燃料电池的具体用途，其中与微生物燃料电池中存在的底物相比，所述产物被氧化并且其中产生电能。

3. 发明申请

WO2006025735A2 ENHANCED SUBSTRATE CONVERSION EFFICIENCY OF FERMENTATION PROCESSES 审中-公开
标题翻译：发酵过程增强基质转化效率
公开(公告)号：WO2006025735A2
公开(公告)日：2006-03-09
申请号：PCT/NL2005000628
申请日：2005-08-31
申请人： AGROTECHNOLOGY AND FOOD INNOVA , SANDERS JOHAN PIETER MARINUS , WEUSTHUIS RUUD ALEXANDER , MOOIBROEK ANDREAS
发明人： SANDERS JOHAN PIETER MARINUS , WEUSTHUIS RUUD ALEXANDER , MOOIBROEK ANDREAS
IPC分类号： C12P1/00 , C12M1/12 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P7/58 , C12P7/64 , C12P13/06 , C12P13/08 , C12P13/14 , C12P37/00
CPC分类号： C12P7/56 , C12P1/00 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/58 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12P13/06 , C12P13/08 , C12P13/14 , C12P37/00
摘要： The present invention relates to the field of fermentation technology. In particular the invention relates to fermentation processes for the production of a first and a second fermentation product by a single production organism wherein the first product is in a more reduced state than the substrate and the second fermentation product is in a more oxidised state than the substrate yet in less oxidised state than the final oxidation product CO 2 , such that the concurrent synthesis of the first and second product in the organism allows recycling of reducing power and can be performed under (partially) anaerobic conditions. The invention further relates to processes in which the first fermentation product is weak alkaline compound and the second fermentation product is a weak acidic compound. In such instances both products may be produced by a single organism in a single fermenter or each the first and second product may be produced by two different organisms that are co-fermented. Co-fermentation may be performed in two separate fermenters that are connected through micro-sieves that allow circulation of soluble medium components between the two fermenters but prevent circulation of the production organisms' cells. The invention also relates to such processes in which the first and second fermentation products are capable of forming a(n) (insoluble) complex or salt.
摘要翻译：本发明涉及发酵技术领域。特别地，本发明涉及用于通过单一生产生物制备第一和第二发酵产物的发酵方法，其中第一产物处于比底物更低的状态，并且第二发酵产物处于比底物，而不是最终氧化产物CO 2 2的氧化态较少，使得生物体中第一和第二产物的同时合成允许再循环还原能力并且可以在（部分）厌氧条件下进行。本发明还涉及第一发酵产物是弱碱性化合物和第二发酵产物是弱酸性化合物的方法。在这种情况下，两种产品可以由单一发酵罐中的单一生物体产生，或者每种第一和第二产物可以由共同发酵的两种不同生物体产生。共发酵可以在通过微筛连接的两个分开的发酵罐中进行，这些发酵罐允许两个发酵罐之间的可溶介质组分循环，但是防止生物生物细胞的循环。本发明还涉及这样的方法，其中第一和第二发酵产物能够形成（n）（不溶性）络合物或盐。

4. 发明申请

WO2012055997A1 PROCESS FOR POLYLACTIC ACID PRODUCTION USING MONASCUS 审中-公开
标题翻译：使用MONASCUS生产聚乳酸的方法
公开(公告)号：WO2012055997A1
公开(公告)日：2012-05-03
申请号：PCT/EP2011/068969
申请日：2011-10-28
申请人： TOTAL S.A. , WEUSTHUIS, Ruud Alexander , WOLBERT, Emil Johan Harald , SPRINGER, Jan , VAN DER OOST, John , EGGINK, Gerrit
发明人： WEUSTHUIS, Ruud Alexander , WOLBERT, Emil Johan Harald , SPRINGER, Jan , VAN DER OOST, John , EGGINK, Gerrit
IPC分类号： C12N1/14 , C12P7/56 , C12R1/645
CPC分类号： C12P7/40 , C12N9/0006 , C12P7/46 , C12P7/56 , C12P7/625 , C12R1/645 , C12Y101/01027
摘要： A process for producing polylactic acid (PLA) comprising the steps: fermenting in a fermentation vessel a micro-organism of the genus Monascusin a medium at a pH less than or equal to 5 under conditions which produce lactic acid into the medium, converting the lacticacid produced into lactide, and polymerizing the lactide to form PLA.
摘要翻译：一种生产聚乳酸（PLA）的方法，包括以下步骤：在产生乳酸的条件下，在pH小于或等于5的条件下，在发酵容器中发酵红曲霉属微生物培养基，转化乳酸生成丙交酯，并使丙交酯聚合形成PLA。

5. 发明申请

WO2012055996A1 USE OF MONASCUS IN ORGANIC ACID PRODUCTION 审中-公开
标题翻译： MONASCUS在有机酸生产中的应用
公开(公告)号：WO2012055996A1
公开(公告)日：2012-05-03
申请号：PCT/EP2011/068968
申请日：2011-10-28
申请人： TOTAL S.A. , WEUSTHUIS, Ruud Alexander , WOLBERT, Emil Johan Harald , SPRINGER, Jan , VAN DER OOST, John , EGGINK, Gerrit
发明人： WEUSTHUIS, Ruud Alexander , WOLBERT, Emil Johan Harald , SPRINGER, Jan , VAN DER OOST, John , EGGINK, Gerrit
IPC分类号： C12R1/645 , C12N9/02 , C12P7/56
CPC分类号： C12P7/40 , C12N9/0006 , C12P7/46 , C12P7/56 , C12P7/625 , C12R1/645 , C12Y101/01027
摘要： The present invention provides tools and methods for producing organic acids using strains of Monascus which are tolerant to high organicacid concentrations at low pH.
摘要翻译：本发明提供使用红曲霉菌株生产有机酸的工具和方法，其耐低pH下的高有机酸浓度。

6. 发明申请

WO2009025547A1 MILD ALKALINE PRETREATMENT AND SIMULTANEOUS SACCHARIFICATION AND FERMENTATION OF LIGNOCELLULOSIC BIOMASS INTO ORGANIC ACIDS 审中-公开
标题翻译：小麦碱性蛋白酶预处理和同时培养的有机酸生物质的发酵和发酵
公开(公告)号：WO2009025547A1
公开(公告)日：2009-02-26
申请号：PCT/NL2008/050545
申请日：2008-08-12
申请人： Wageningen Universiteit , BAKKER, Robert Reurd Christophor , DE JONG, Ed , MAAS, Ronald Hubertus Wilhelmus , WEUSTHUIS, Ruud Alexander , VISSER, Diana , WINKELAAR, Hendrik Martinus , JANSEN, Mickel Leonardus August
发明人： BAKKER, Robert Reurd Christophor , DE JONG, Ed , MAAS, Ronald Hubertus Wilhelmus , WEUSTHUIS, Ruud Alexander , VISSER, Diana , WINKELAAR, Hendrik Martinus , JANSEN, Mickel Leonardus August
IPC分类号： C12P7/56 , C12P7/40 , C12N1/22 , C12M1/36
CPC分类号： C12P7/56 , C12M41/26 , C12N1/22 , C12P7/40 , C12P2201/00 , C12P2203/00
摘要： The invention relates to a method for the production of a fermentation product from lignocellulosic biomass, to a reactor to carry out the method and to use of the reactor to produce a fermentation product.
摘要翻译：本发明涉及一种从木质纤维素生物质生产发酵产物的方法，涉及反应器以实施该方法并使用该反应器来生产发酵产物。

7. 发明申请

WO2006025735A3 ENHANCED SUBSTRATE CONVERSION EFFICIENCY OF FERMENTATION PROCESSES 审中-公开
公开(公告)号：WO2006025735A3
公开(公告)日：2006-03-09
申请号：PCT/NL2005/000628
申请日：2005-08-31
申请人： AGROTECHNOLOGY AND FOOD INNOVATIONS B. V. , SANDERS, Johan, Pieter, Marinus , WEUSTHUIS, Ruud, Alexander , MOOIBROEK, Andreas
发明人： SANDERS, Johan, Pieter, Marinus , WEUSTHUIS, Ruud, Alexander , MOOIBROEK, Andreas
IPC分类号： C12P1/00 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P7/58 , C12P7/64 , C12P13/06 , C12P13/08 , C12P13/14 , C12P37/00 , C12M1/12
摘要： The present invention relates to the field of fermentation technology. In particular the invention relates to fermentation processes for the production of a first and a second fermentation product by a single production organism wherein the first product is in a more reduced state than the substrate and the second fermentation product is in a more oxidised state than the substrate yet in less oxidised state than the final oxidation product CO 2 , such that the concurrent synthesis of the first and second product in the organism allows recycling of reducing power and can be performed under (partially) anaerobic conditions. The invention further relates to processes in which the first fermentation product is weak alkaline compound and the second fermentation product is a weak acidic compound. In such instances both products may be produced by a single organism in a single fermenter or each the first and second product may be produced by two different organisms that are co-fermented. Co-fermentation may be performed in two separate fermenters that are connected through micro-sieves that allow circulation of soluble medium components between the two fermenters but prevent circulation of the production organisms' cells. The invention also relates to such processes in which the first and second fermentation products are capable of forming a(n) (insoluble) complex or salt.

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