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1. 发明申请

WO2011077281A3 SKIN PREPARATION THAT IMMOBILIZES BACTERIA 审中-公开
标题翻译：皮肤准备，可以固定细菌
公开(公告)号：WO2011077281A3
公开(公告)日：2011-11-17
申请号：PCT/IB2010055330
申请日：2010-11-22
申请人： KIMBERLY CLARK CO , SCHORR PHILLIP A , HOFFMAN DOUGLAS R , WEART ILONA F , YANG KAIYUAN
发明人： SCHORR PHILLIP A , HOFFMAN DOUGLAS R , WEART ILONA F , YANG KAIYUAN
IPC分类号： A61B19/08 , A61F13/02 , A61L15/20 , A61L15/42 , A61L31/14
CPC分类号： A61K31/00 , A61K31/05 , A61K31/14 , A61K31/155 , A61K33/00 , A61K33/18 , A61K47/32 , A61L26/0014 , A61L26/0066 , C08L33/12
摘要： Skin sealants are usually applied over skin preps to seal the skin and hold any remaining bacteria in place prior to surgical incisions. This sealant is generally left on the skin after surgery. This two step process is time consuming, as each layer must dry before the next one is applied. A skin preparation is provided that immobilizes at least 95 percent of bacteria on the skin and is essentially free of cyanoacrylate. The skin preparation has a fugitive solvent and may also have antimicrobial compounds like iodophors, biguanides, phenols, quaternary amines, antibiotics and metals. This skin preparation may be used without an additional skin sealant or incise applied over it prior to surgery.
摘要翻译：通常将皮肤密封剂施用于皮肤制备物上以密封皮肤并在手术切口之前将任何残留的细菌保持在适当的位置。这种密封胶通常在手术后留在皮肤上。这两个步骤过程非常耗时，因为在应用下一个层之前，每层必须干燥。提供了一种皮肤制剂，其将至少95％的细菌固定在皮肤上并且基本上不含氰基丙烯酸酯。该皮肤制剂具有挥发性溶剂，并且还可以具有抗微生物化合物，如碘伏，双胍，酚，季胺，抗生素和金属。这种皮肤准备可以在手术前使用，而不需要额外的皮肤密封剂或切口。

2. 发明申请

WO2010001291A3 SEALANT APPLICATOR AND METHOD 审中-公开
标题翻译：密封剂涂布器和方法
公开(公告)号：WO2010001291A3
公开(公告)日：2010-04-08
申请号：PCT/IB2009052652
申请日：2009-06-20
申请人： KIMBERLY CLARK CO , BREWER JOHN , CESA JOSEPH A , HOUDE AJAY Y , WEART ILONA F
发明人： BREWER JOHN , CESA JOSEPH A , HOUDE AJAY Y , WEART ILONA F
IPC分类号： A45D34/04 , A45D34/00 , A61K8/37
CPC分类号： A61M35/003 , A61B17/00491 , A61B2017/00495
摘要： An applicator and associated method for applying a microbial sealant system and methods for controlling the polymerization of a microbial sealant, the applicator having a housing; a first reservoir element associated with the housing, the first reservoir element containing a polymerization control liquid; a first applicator element adapted to apply a substantially uniform layer polymerization control liquid to the skin; and a second reservoir element integrated with the housing and containing a liquid composed of cyanoacrylate pre-polymers that having polymerization characteristics influenced by the polymerization control liquid, the second reservoir being in fluid communication with a second applicator element adapted to apply a substantially uniform layer of the cyanoacrylate pre-polymers over the layer of polymerization control liquid.
摘要翻译：一种用于施用微生物密封剂系统的施用器和相关方法以及用于控制微生物密封剂聚合的方法，所述施用器具有壳体; 与所述壳体相关联的第一储存器元件，所述第一储存器元件包含聚合控制液体; 第一涂敷器元件，其适于将基本上均匀的层聚合控制液体施加至皮肤; 以及第二储存器元件，与壳体集成并且容纳由氰基丙烯酸酯预聚物组成的液体，所述液体具有受聚合控制液体影响的聚合特性，第二储存器与第二涂敷器元件流体连通，所述第二涂敷器元件适于将基本均匀的在聚合控制液体层上的氰基丙烯酸酯预聚物。

3. 发明申请

WO2009060327A3 COVERAGE INDICATING TECHNOLOGY FOR SKIN SEALANTS USING TANNATES 审中-公开
标题翻译：使用TANNATES的皮肤密封剂的覆盖技术指标
公开(公告)号：WO2009060327A3
公开(公告)日：2009-09-24
申请号：PCT/IB2008054072
申请日：2008-10-03
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , SMITH MOLLY K , WEART ILONA F , SCHORR PHILLIP A
发明人： MACDONALD JOHN GAVIN , SMITH MOLLY K , WEART ILONA F , SCHORR PHILLIP A
IPC分类号： A61L24/04 , G01N31/22
CPC分类号： A61K33/18 , A61K9/0014 , A61K47/26 , A61K47/44
摘要： A composition having various color changing tannates may be used to indicate that the composition has dried. The tannates change color in contact with an acid. The composition may be, for example, a skin prep, skin sealant, food product, paint or other building material or other product that undergoes a phase change. The tannate may be added either directly to the composition, incorporated into a sponge on an applicator through which the composition is dispensed and applied, applied separately or applied simultaneously from a separate reservoir. The amount of tannate in the composition can be adjusted to provide a visual cue to the user of the application area and the extent of cure.
摘要翻译：具有各种变色丹宁酸的组合物可用于表示组合物已干燥。丹宁酸改变与酸接触的颜色。组合物可以是例如皮肤制剂，皮肤密封剂，食品，油漆或其他建筑材料或经历相变的其它产品。丹宁酸可以直接添加到组合物中，并入施用组合物中的海绵中，组合物通过其分配和施用，单独施用或从单独的储存器同时施用。可以调整组合物中的单宁酸盐的量，以向使用者提供视觉提示和施用范围。

4. 发明申请

WO2006068665A1 ANTIMICROBIAL COMPOSITIONS COMPRISING A NATURAL AGENT SELECTED FROM GALLIC ACID, EUCALYPTOL, NARINGIN, A JASMONIC ACID COMPOUND AND ANY COMBINATION THEREOF 审中-公开
标题翻译：包含选自苹果酸，依托替尼，纳林宁，氨基酸化合物的天然药物的抗微生物组合物及其任何组合
公开(公告)号：WO2006068665A1
公开(公告)日：2006-06-29
申请号：PCT/US2005/025366
申请日：2005-07-18
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , GREENE, Sharon, Linda , HUANG, Yanbin , HUANG, Lei , WEART, Ilona, F. , YANG, Shu-Ping , MALIK, Sohail , JOHNSON, Robert, B.
发明人： GREENE, Sharon, Linda , HUANG, Yanbin , HUANG, Lei , WEART, Ilona, F. , YANG, Shu-Ping , MALIK, Sohail , JOHNSON, Robert, B.
IPC分类号： A61K31/19 , A61K31/192 , A61K31/215 , A61K31/352 , A61K31/7048 , A61K36/61 , A61K36/752 , A61K45/06 , A61P31/10
CPC分类号： A61K45/06 , A61K31/19 , A61K31/215 , A61K31/7048 , A61K36/61 , A61K2300/00
摘要： The present invention is directed to anti-microbial compositions and methods for treating fungal and yeast infections. The compositions comprise a natural agent selected from the group consisting of gallic acid, eucalyptol, naringin, a jasmonic acid compound, and any combination thereof.
摘要翻译：本发明涉及用于治疗真菌和酵母菌感染的抗微生物组合物和方法。组合物包含选自没食子酸，桉油醇，柚皮苷，茉莉酸化合物及其任何组合的天然剂。

5. 发明申请

WO2004093759A8 THERMAL THERAPY SLEEVE 审中-公开
标题翻译：热疗法套管
公开(公告)号：WO2004093759A8
公开(公告)日：2004-12-16
申请号：PCT/US2004004065
申请日：2004-02-11
申请人： KIMBERLY CLARK CO , AGARWAL NAVEEN , FISH JEFFREY E , WEART ILONA F , WILLIS JEFFREY M
发明人： AGARWAL NAVEEN , FISH JEFFREY E , WEART ILONA F , WILLIS JEFFREY M
IPC分类号： A61F7/00 , A61F7/02 , A61F7/03
CPC分类号： A61F7/03 , A61F7/106 , A61F2007/0098 , A61F2007/023 , A61F2007/0276 , A61F2007/0292
摘要： A flexible thermal therapy sleeve (50) is disclosed. The sleeve includes a first layer (52) including a first phase change material (56) having a transition temperature of from about -10°C to about 40°C, and a second layer (58) including a second phase change material having a transition temperature of from about 35°C to about 65°C. The first layer is joined to the second layer to form at least a partial enclosure having an opening through which a thermoactive material may be inserted and removed.
摘要翻译：公开了一种柔性热疗套（50）。所述套筒包括第一层（52）和第二层（58），所述第一层包括具有约-10℃至约40℃的转变温度的第一相变材料（56），所述第二层包括第二相变材料，所述第二相变材料具有从约35℃至约65℃的转变温度。第一层连接到第二层以形成至少一个具有开口的部分外壳，热活性材料可通过该开口插入和移除。

6. 发明申请

WO2010070588A2 PLASTICIZER FOR THERMOPLASTIC POLYMER MATERIALS 审中-公开
标题翻译：用于热塑性聚合物材料的塑化剂
公开(公告)号：WO2010070588A2
公开(公告)日：2010-06-24
申请号：PCT/IB2009/055771
申请日：2009-12-15
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , MACDONALD, John, Gavin , ELSHANI, Teuta , HRISTOV, Hristo, A. , SMITH, Molly, K. , WEART, Ilona, F.
发明人： MACDONALD, John, Gavin , ELSHANI, Teuta , HRISTOV, Hristo, A. , SMITH, Molly, K. , WEART, Ilona, F.
IPC分类号： C08L67/04 , C08K5/15 , C08J5/00
CPC分类号： C08K5/0016 , A61L15/42 , A61L29/141 , A61L31/141 , C08K5/0033 , C08K5/1545 , C08L67/04
摘要： A thermoplastic polymeric composition having a xanthene or xanthenes-based compound as a plasticizer, a method to modify the thermoplastic polymeric materials to increase their relative plasticity while maintaining good strength or "toughness" characteristics, and various articles of manufacture that can be made using the polymer composition are described.
摘要翻译：具有呫吨或呫吨酮类化合物作为增塑剂的热塑性聚合物组合物，在保持良好强度或“韧性”特性的同时改性热塑性聚合物材料以提高其相对可塑性的方法，以及可以使用聚合物组成描述。

7. 发明申请

WO2009047663A2 SYSTEM FOR PROVIDING A METHOD FOR APPLYING A SKIN SEALANT HAVING A PHASE CHANGE VISUAL INDICATING COMPONENT 审中-公开
标题翻译：提供具有相变视觉指示组件的皮肤密封剂的方法的系统
公开(公告)号：WO2009047663A2
公开(公告)日：2009-04-16
申请号：PCT/IB2008053779
申请日：2008-09-17
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , SMITH MOLLY K , WEART ILONA F , SCHORR PHILLIP A
发明人： MACDONALD JOHN GAVIN , SMITH MOLLY K , WEART ILONA F , SCHORR PHILLIP A
IPC分类号： A61M35/00
CPC分类号： A61M35/003 , A61B2017/00495
摘要： A system for providing a method of sealing skin with a film forming polymer is provided. The system includes providing an at least two part applicator containing a sealant composition in one or more frangible containers, providing instructions for using the applicator associated therewith, where the method including moving at least one of said applicator parts from a first position to a second position and applying said sealant to skin. The composition has film former, a plasticizer and 3000 to 10000 ppm of a dye that changes color when is undergoes a phase change. The color change is visible to a human eye under normal light conditions. changing dyes may be used to indicate that the composition has dried. The dyes change color in response to the phase change, i.e., drying of the film former. The dye may be added either directly to the composition, incorporated into a sponge on an applicator through which the composition is dispensed and applied, applied separately or applied simultaneously from a separate reservoir. The amount of dye in the composition can be adjusted to provide a visual cue to the user of the application area and the extent of cure though should generally be in the range of 3000 to 10000 ppm.
摘要翻译：提供了一种用于提供用成膜聚合物密封皮肤的方法的系统。该系统包括在一个或多个易碎容器中提供含有密封剂组合物的至少两个部分施用器，其提供使用与其相关联的施用器的指导，其中所述方法包括将所述施用器部件中的至少一个从第一位置移动到第二位置并将所述密封剂施加到皮肤上。该组合物具有成膜剂，增塑剂和3000至10000ppm的染料，当发生相变时颜色变化。在正常光照条件下，人眼可见颜色变化。可以使用改变的染料来表示组合物已经干燥。染料根据相变而变色，即成膜剂的干燥。染料可以直接添加到组合物中，并入施用器上的海绵中，组合物通过其分配和施加，单独施用或从单独的储存器同时施用。可以调整组合物中的染料的量以向使用者提供视觉提示并且固化程度通常应在3000至10000ppm的范围内。

8. 发明申请

WO2009047655A2 PHASE CHANGE VISUAL INDICATING COMPOSITION 审中-公开
标题翻译：相变视觉指示组合物
公开(公告)号：WO2009047655A2
公开(公告)日：2009-04-16
申请号：PCT/IB2008/052825
申请日：2008-07-14
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , MACDONALD, John, Gavin , SMITH, Molly, K. , WEART, Ilona, F. , SCHORR, Phillip, A.
发明人： MACDONALD, John, Gavin , SMITH, Molly, K. , WEART, Ilona, F. , SCHORR, Phillip, A.
IPC分类号： A61K8/00 , A61K49/00 , C12Q1/04
CPC分类号： A61K33/18 , A61L26/0061 , A61L26/0066 , A61L26/0071 , A61L2300/202 , A61L2300/404 , A61L2300/442
摘要： A skin sealant composition of a film former and a plasticizer and having various color changing dyes may be used to indicate that the composition has dried. The dyes change color in response to the phase change, i.e., drying of the film former. The dye may be added either directly to the composition, incorporated into a sponge on an applicator through which the composition is dispensed and applied, applied separately or applied simultaneously from a separate reservoir. The amount of dye in the composition can be adjusted to provide a visual cue to the user of the application area and the extent of cure though should generally be in the range of 3000 to 10000 ppm.
摘要翻译：可以使用成膜剂和增塑剂并且具有各种变色染料的表皮密封剂组合物来表示组合物已经干燥。染料响应相变而改变颜色，即干燥成膜剂。染料可以直接加入到组合物中，在涂抹器中加入海绵中，通过该涂抹器分配和施用组合物，分开施用或者从单独的储存器同时施用。可以调节组合物中染料的量，以向使用区域的使用者提供视觉提示，并且固化的程度通常应该在3000-10000ppm的范围内。

9. 发明申请

WO2006046990A1 DETECTION OF TRICHOMONAS 审中-公开
标题翻译：检测TRICHOMONAS
公开(公告)号：WO2006046990A1
公开(公告)日：2006-05-04
申请号：PCT/US2005/026720
申请日：2005-07-27
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , WEART, Ilona, F. , YANG, Shu-Ping
发明人： WEART, Ilona, F. , YANG, Shu-Ping
IPC分类号： G01N33/569 , G01N33/543 , C12Q1/40 , C12M1/40
CPC分类号： C12Q1/04 , A61B10/0045 , A61B2010/0006 , A61B2010/0074 , A61F13/202 , A61F13/2074 , A61F2013/00429 , A61F2013/8473 , G01N33/54366 , G01N33/56905
摘要： The present invention is directed to diagnostic devices and methods for detecting Trichomonas infections.
摘要翻译：本发明涉及用于检测毛滴虫感染的诊断装置和方法。

10. 发明申请

WO2004093887A1 COMPOSITIONS COMPRISING HYALURONIC ACID FOR THE PREVENTION OF UROGENITAL INFECTIONS 审中-公开
标题翻译：包含防腐剂用于预防感染的组合物
公开(公告)号：WO2004093887A1
公开(公告)日：2004-11-04
申请号：PCT/US2004/008431
申请日：2004-03-19
申请人： KIMBERLY-CLARK WORLDWIDE INC. , YANG, Shu-Ping , HUANG, Yanbin , WEART, Ilona, F.
发明人： YANG, Shu-Ping , HUANG, Yanbin , WEART, Ilona, F.
IPC分类号： A61K31/728
CPC分类号： A61F13/8405 , A61F13/2051 , A61K31/728 , Y02A50/473
摘要： The invention provides hyaluronic acid compounds and derivatives thereof for preventing urogenital infections by a variety of pathogens, as well as compositions, articles and methods for treating and preventing urogenital infections.
摘要翻译：本发明提供了用于预防各种病原体的泌尿生殖感染的透明质酸化合物及其衍生物，以及用于治疗和预防泌尿生殖器感染的组合物，制品和方法。

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