专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009136930A1 METHOD AND SYSTEM FOR MONITORING GASTROINTESTINAL FUNCTION AND PHYSIOLOGICAL CHARACTERISTICS 审中-公开
标题翻译：监测胃肠功能和生理特征的方法和系统
公开(公告)号：WO2009136930A1
公开(公告)日：2009-11-12
申请号：PCT/US2008/063005
申请日：2008-05-08
申请人： SMITHKLINE BEECHAM CORPORATION , WALKER, Dwight, Sherod
发明人： WALKER, Dwight, Sherod
IPC分类号： A61B8/00
CPC分类号： A61B7/008 , A61B5/0205 , A61B5/024 , A61B5/0402 , A61B5/0816 , A61B5/1123 , A61B5/145 , A61B5/42 , A61B5/4255
摘要： A system and method for evaluating gastrointestinal motility and, optionally, other physiological characteristics (e.g., pulse rate) that can be effectively employed to acquire one or more signals associated with acoustic energy (i.e. sound) emanating from an abdominal region of a body and determine at least one gastrointestinal parameter or event based on the acoustic energy signal(s) is described. The gastrointestinal parameter can include a gastrointestinal event, including gastrointestinal mixing, emptying, contraction and propulsion, and gastrointestinal transit time, or a gastrointestinal system disorder, including reflux disease, irritable bowel disease, ulcerative colitis, constipation, diarrhea, and a migrating motor complex disorder.
摘要翻译：用于评估胃肠运动性和可选的其他生理特征（例如，脉搏率）的系统和方法，所述生理特征可以有效地用于获取一个或多个与声能（即，声音）相关的信号，所述声能源描述了身体的腹部区域并基于声能信号确定至少一个胃肠参数或事件。胃肠参数可包括胃肠道事件，包括胃肠道混合，排空，收缩和推进以及胃肠通过时间或胃肠系统病症，包括反流性疾病，肠易激综合征，溃疡性结肠炎，便秘，腹泻和迁移运动综合征性病症。

2. 发明申请

WO2006036522A1 LUMINESCENSE SENSOR APPARATUS AND METHOD 审中-公开
标题翻译：发光传感器装置和方法
公开(公告)号：WO2006036522A1
公开(公告)日：2006-04-06
申请号：PCT/US2005/032421
申请日：2005-09-13
申请人： GLAXO GROUP LIMITED , WALKER, Dwight, Sherod
发明人： WALKER, Dwight, Sherod
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01N2021/6476 , G01N2201/062
摘要： A system for use in analyzing a pharmaceutical composition having at least one constituent comprising a luminescence sensor having an integral low current light source, the sensor being adapted to direct a plurality of radiation pulses to the pharmaceutical composition and detect luminescence emitted from the composition constituent, the sensor being further adapted to provide at least one luminescence signal corresponding to the detected luminescence, and control means in communication with the sensor for controlling the sensor and analyzing the luminescence signal.
摘要翻译：一种用于分析具有至少一种成分的药物组合物的系统，所述组合物包含具有整体低电流光源的发光传感器，所述传感器适于将多个辐射脉冲引导到药物组合物并检测从组合物成分发出的发光，所述传感器还适于提供对应于检测到的发光的至少一个发光信号，以及与所述传感器通信的控制装置，用于控制所述传感器并分析所述发光信号。

3. 发明申请

WO2006034202A1 BLENDING SYSTEM AND METHOD 审中-公开
标题翻译：混合系统和方法
公开(公告)号：WO2006034202A1
公开(公告)日：2006-03-30
申请号：PCT/US2005/033498
申请日：2005-09-19
申请人： GLAXO GROUP LIMITED , SCHERZER, Raymond, Herbert , WALKER, Dwight, Sherod , GILLHAM, Charles, Rupert , GILMOUR, Christopher, Michael , VAN DEN BAN, Sander , TAYLOR, Andrew, Rodwrick , FOSTER, Stephen, Charles
发明人： SCHERZER, Raymond, Herbert , WALKER, Dwight, Sherod , GILLHAM, Charles, Rupert , GILMOUR, Christopher, Michael , VAN DEN BAN, Sander , TAYLOR, Andrew, Rodwrick , FOSTER, Stephen, Charles
IPC分类号： B01F15/02
CPC分类号： B01F15/00207 , B01F3/18 , B01F7/00125 , B01F7/00141 , B01F7/18 , B01F13/1005 , B01F15/00155 , B01F15/00175 , B01F15/00201 , B01F15/0024 , B01F15/00285 , B01F15/00292 , B01F15/0035 , B01F15/00389 , B01F15/00909 , B01F15/0445 , B01F2215/0032
摘要： A blending system for and a method of providing a continuous supply of a blend, the system comprising: a blending unit (3) operative to blend batches of a blend comprising a plurality of constituent components; a blend feeding unit (25) operative to receive each blended batch from the blending unit (3) and deliver a continuous supply of the blend; and a control unit (33) for controlling operation of the blending unit (3) such as intermittently to blend batches of the blend.
摘要翻译：一种用于提供混合物的连续供应的共混系统和方法，所述系统包括：混合单元（3），其可操作地混合包含多个构成组分的混合物批料; 混合进料单元（25），其可操作以从混合单元（3）接收每个混合批料并输送连续供应的共混物; 以及用于控制混合单元（3）的操作的控制单元（33），例如间歇地混合共混物的批次。

4. 发明申请

WO03032020A2 REFRACTIVE INDEX PROBE APPARATUS AND SYSTEM 审中-公开
标题翻译：折射指数探测器和系统
公开(公告)号：WO03032020A2
公开(公告)日：2003-04-17
申请号：PCT/US0231470
申请日：2002-10-03
申请人： SMITHKLINE BEECHAM CORP , BARGER LEE ALLEN , PARTRIDGE JOHN JOSEPH , WALKER DWIGHT SHEROD
发明人： BARGER LEE ALLEN , PARTRIDGE JOHN JOSEPH , WALKER DWIGHT SHEROD
IPC分类号： G01N21/41 , G01N21/43 , G02B6/00 , G02B
CPC分类号： G01N21/431
摘要： A refractive index device (10) comprising a probe member (16) having a sensing region (24) and a length of optic fiber (40) having a refract region (44) and a reflecting surface (48) disposed proximate the distal end adapted to substantially redirect said light transmitted through the fiber, the fiber being substantially disposed in the probe member wherein the refract region (44) is disposed proximate the sensing region (24).
摘要翻译：包括具有感测区域（24）的探针构件（16）和具有折射区域（44）的光纤长度（40）的折射率装置（10）和邻近所述远端设置的反射表面（48）适于以基本上重新定向透射通过纤维的所述光，所述纤维基本上设置在所述探针构件中，其中所述折射区域（44）设置在所述感测区域（24）附近。

5. 发明申请

WO2002065104A3 METHOD AND APPARATUS FOR IN-SITU SPECTROSCOPIC DETECTION AND ANALYSIS OF POLYMORPHIC MODIFICATIONS 审中-公开
公开(公告)号：WO2002065104A3
公开(公告)日：2002-08-22
申请号：PCT/US2002/004263
申请日：2002-02-13
申请人： SMITHKLINE BEECHAM CORPORATION , WALKER, Dwight, Sherod , WILLIAMS, Wesley, Bryant
发明人： WALKER, Dwight, Sherod , WILLIAMS, Wesley, Bryant
IPC分类号： G01N21/35
摘要： An apparatus for in-situ detection of polymorphic transformations comprising a probe body having first flow passage means and a retainer member, a screen member having second flow passage means adapted to capture at least one crystal structure of the organic compound, a cap having third flow passage means and means for introducing into the third flow passage means, the cap including first engagement means adapted to engage the retainer member, radiation transmission means for transmitting an excitation light of a given wavelength to at least a first sample of the organic compound, an outlet tube having fourth flow passage means, and pump means for providing a first flow rate of the organic compound into and through the first, second, third and fourth flow passage means.

6. 发明申请

WO02065104A2 METHOD AND APPARATUS FOR IN-SITU SPECTROSCOTPIC DETECTION AND ANALYSIS OF POLYMORPHIC MODIFICATIONS 审中-公开
标题翻译：用于现场光谱检测和多态性改性分析的方法和装置
公开(公告)号：WO02065104A2
公开(公告)日：2002-08-22
申请号：PCT/US0204263
申请日：2002-02-13
申请人： SMITHKLINE BEECHAM CORP , WALKER DWIGHT SHEROD , WILLIAMS WESLEY BRYANT
发明人： WALKER DWIGHT SHEROD , WILLIAMS WESLEY BRYANT
IPC分类号： G01N21/85 , G01N21/35
CPC分类号： G01N21/8507
摘要： An apparatus for in-situ detection of polymorphic transformations comprising a probe body having first flow passage means and a retainer member, a screen member having second flow passage means adapted to capture at least one crystal structure of the organic compound, a cap having third flow passage means and means for introducing into the third flow passage means, the cap including first engagement means adapted to engage the retainer member, radiation transmission means for transmitting an excitation light of a given wavelength to at least a first sample of the organic compound, an outlet tube having fourth flow passage means, and pump means for providing a first flow rate of the organic compound into and through the first, second, third and fourth flow passage means.
摘要翻译：一种用于原位检测多态转化的装置，包括具有第一流动通道装置和保持器构件的探针体，筛网构件，具有适于捕获有机化合物的至少一种晶体结构的第二流动通道装置，具有第三流动的盖用于引入第三流动通道装置的通道装置和装置，其包括适于接合保持构件的第一接合装置，用于将给定波长的激发光传递至至少第一有机化合物样品的辐射传递装置，具有第四流动通道装置的出口管和用于将有机化合物的第一流量提供到第一，第二，第三和第四流动通道装置中的泵装置。

7. 发明申请

WO2002059599A2 SYSTEM AND METHOD FOR IN VITRO ANALYSIS OF THERAPEUTIC AGENTS 审中-公开
标题翻译：用于治疗药物的体外分析系统和方法
公开(公告)号：WO2002059599A2
公开(公告)日：2002-08-01
申请号：PCT/US2002/002223
申请日：2002-01-25
申请人： SMITHKLINE BEECHAM CORPORATION , WALKER, Dwight, Sherod , PATRICK, Mark, Austin
发明人： WALKER, Dwight, Sherod , PATRICK, Mark, Austin
IPC分类号： G01N33/487
CPC分类号： G01N21/05 , G01N21/31
摘要： A system and method for in vitro analysis of therapeutic agents comprising a reservoir adapted to hold a therapeutic agent, a first flow cell having a first cell chamber adapted to receive at least a first sample of the therapeutic agent, a second flow cell having a second cell chamber adapted to receive at least a second sample of the therapeutic agent, the first flow cell having a first path length (b e ') and the second flow cell having a second path length (b e "), the first path length being substantially equal to a sensitivity factor (f) x b e ", a membrane chamber having a biological cell membrane therein adapted to receive at least a third sample of the therapeutic agent, the membrane chamber being further adapted to detect the membrane potential of the biological cell membrane; and spectroscopic detection means for detecting the spectral characteristics of the first and second therapeutic agent samples.
摘要翻译：一种用于体外分析治疗剂的系统和方法，所述治疗剂包括适于保持治疗剂的储存器，具有适于接收所述治疗剂的至少第一样品的第一细胞室的第一流动池，具有第二流体池所述第一流动池具有第一路径长度（be'），所述第二流动池具有第二路径长度（be“），所述第一路径长度基本相等对于敏感性因子（f）x为“，具有其中适于接收至少第三样品的治疗剂的生物细胞膜的膜室，所述膜室还适于检测所述生物细胞膜的膜电位; 以及用于检测第一和第二治疗剂样品的光谱特性的光谱检测装置。

8. 发明申请

WO2010005865A1 METHODS, APPARATUS AND SYSTEMS EMPLOYING MULTIPLE ENERGY SOURCES FOR ANALYZING COMPOSITIONS 审中-公开
标题翻译：采用多种能源分析方法，装置和系统进行分析
公开(公告)号：WO2010005865A1
公开(公告)日：2010-01-14
申请号：PCT/US2009/049514
申请日：2009-07-02
申请人： SMITHKLINE BEECHAM CORPORATION , DICKENS, Jason , WALKER, Dwight Sherod
发明人： DICKENS, Jason , WALKER, Dwight Sherod
IPC分类号： G01J3/00
CPC分类号： G01J3/10 , G01N21/31 , G01N21/33 , G01N21/41 , G01N21/6402 , G01N21/6428 , G01N21/76 , G01N21/8507 , G01N2021/6417 , G01N2021/8411
摘要： An apparatus for analyzing a composition includes an excitation source adapted to transmit incident energy, the excitation source comprising an array of energy emitting sources, and a plurality of photometric detectors adapted to receive radiation emitted from the composition when the incident radiation is transmitted thereto.
摘要翻译：用于分析组合物的装置包括适于透射入射能量的激发源，所述激发源包括能量发射源阵列，以及多个测光检测器，适于在入射辐射传输时接收从组合物发射的辐射。

9. 发明申请

WO2009137341A1 METHOD AND SYSTEM FOR MONITORING GASTROINTESTINAL FUNCTION AND PHYSIOLOGICAL CHARACTERISTICS 审中-公开
标题翻译：监测胃肠功能和生理特征的方法和系统
公开(公告)号：WO2009137341A1
公开(公告)日：2009-11-12
申请号：PCT/US2009/042471
申请日：2009-05-01
申请人： SMITHKLINE BEECHAM CORPORATION , WALKER, Dwight, Sherod
发明人： WALKER, Dwight, Sherod
IPC分类号： A61B5/00
CPC分类号： A61B7/008 , A61B5/42 , A61B5/6805
摘要： A system and method for evaluating gastrointestinal motility and, optionally, other physiological characteristics (e.g., pulse rate) that can be effectively employed to acquire one or more signals associated with acoustic energy (i.e. sound) emanating from an abdominal region of a body and determine at least one gastrointestinal parameter or event based on the acoustic energy signal(s) is described. The gastrointestinal parameter can include a gastrointestinal event, including gastrointestinal mixing, emptying, contraction and propulsion, and gastrointestinal transit time, or a gastrointestinal system disorder, including reflux disease, irritable bowel disease, ulcerative colitis, constipation, diarrhea, and a migrating motor complex disorder.
摘要翻译：一种用于评估胃肠运动性和任选的其他生理特征（例如，脉搏率）的系统和方法，其可以有效地用于获取与从身体的腹部区域发出的声能（即声音）相关联的一个或多个信号，并且确定描述了基于声能信号的至少一个胃肠参数或事件。胃肠道参数可以包括胃肠道事件，包括胃肠混合，排空，收缩和推进，以及胃肠道通过时间，或胃肠系统疾病，包括反流疾病，肠易激肠，溃疡性结肠炎，便秘，腹泻和迁移运动综合征紊乱。

10. 发明申请

WO2007098392A3 METHOD AND SYSTEM FOR CHEMICAL SPECIFIC SPECTRAL ANALYSIS 审中-公开
标题翻译：化学光谱分析方法与系统
公开(公告)号：WO2007098392A3
公开(公告)日：2008-09-18
申请号：PCT/US2007062294
申请日：2007-02-16
申请人： GLAXO GROUP LTD , WALKER DWIGHT SHEROD
发明人： WALKER DWIGHT SHEROD
IPC分类号： G01J5/02
CPC分类号： G01N21/359 , G01N21/3563 , G01N21/3577
摘要： A method for chemical specific spectral analysis of a pharmaceutical composition (100) comprising the steps of transmitting light having a wavelength in the range of 800 - 2500 nm to a pharmaceutical composition, whereby the pharmaceutical composition interacts with the transmitted light, the interaction including the emission of a first light, directing the first light to a first multi-optical element (14) adapted to selectively pass a predetermined first fraction of the first light to pass there through, the first light fraction corresponding to the absorbance spectrum of an active contained in the pharmaceutical composition, and directing the first light fraction to a first NIR camera (16a) adapted to receive the first light fraction and provide a first NIR image of the pharmaceutical composition.
摘要翻译：一种用于药物组合物（100）的化学特异性光谱分析的方法，包括以下步骤：将波长在800-2500nm范围内的光透射到药物组合物，由此药物组合物与透射光相互作用，包括发射第一光，将第一光引导到适于选择性地通过第一光的预定第一部分以通过其中的第一多光学元件（14），与包含的活性物质的吸收光谱相对应的第一轻馏分并且将第一轻馏分引导到适于接收第一轻馏分并提供药物组合物的第一近红外图像的第一近红外照相机（16a）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式