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1. 发明申请

WO2011094571A8 METHOD FOR IMPROVING THE FUEL EFFICIENCY OF ENGINE OIL COMPOSITIONS FOR LARGE LOW AND MEDIUM SPEED ENGINES BY REDUCING THE TRACTION COEFFICIENT 审中-公开
标题翻译：通过减少牵引系数来提高大型低速和中速发动机的机油组合物的燃料效率的方法
公开(公告)号：WO2011094571A8
公开(公告)日：2011-08-04
申请号：PCT/US2011/022965
申请日：2011-01-28
申请人： EXXONMOBIL RESEARCH AND ENGINEERING COMPANY , TELLIER, Kathleen, H. , CAREY, Vincent, Mark , CROUTHAMEL, Kevin, Louis
发明人： TELLIER, Kathleen, H. , CAREY, Vincent, Mark , CROUTHAMEL, Kevin, Louis
IPC分类号： C10M111/04 , C10N30/06 , C10N40/25 , C10N40/26
摘要： The present invention is directed to a method for improving the fuel efficiency of low and medium speed engine oil compositions by reducing the traction coefficient of the oil by formulating the oil using at least two base stocks of different kinematic viscosity wherein the differences in kinematic viscosity between the base stocks is at least 30 mm 2 /s.
摘要翻译：本发明涉及一种通过使用至少两种不同运动学的基础油配制油来降低油的牵引系数来提高低速和中速发动机油组合物的燃料效率的方法其中基础油料之间的运动粘度差异至少为30mm 2 / s。

2. 发明申请

WO2007012795A1 EXTRACTION DEVICE FOR USE WHEN EXTRACTING A CERAMIC FOAM FILTER 审中-公开
标题翻译：提取陶瓷泡沫过滤器时使用的萃取装置
公开(公告)号：WO2007012795A1
公开(公告)日：2007-02-01
申请号：PCT/GB2006/002232
申请日：2006-06-19
申请人： PYROTEK INCORPORATED , VINCENT, Mark
发明人： VINCENT, Mark
IPC分类号： F16B25/10 , C22B9/02 , C22B21/06
CPC分类号： C22B21/066 , C22B9/023 , F16B25/103 , Y02P10/234 , Y10T29/49815 , Y10T29/53 , Y10T29/53687
摘要： An extraction device is provided for use when extracting a ceramic foam filter, as used for example in the production and processing of aluminium. The extraction device includes an anchor device (1) having an anchor body (2) suitable for driving into the filter, and a screw thread (8) that extends along at least part of the length of the anchor body, for engagement with the filter.
摘要翻译：提取提取装置用于提取陶瓷泡沫过滤器时，例如在铝的生产和加工中使用。提取装置包括具有适于驱动到过滤器中的锚固体（2）的锚定装置（1）和沿着锚固体长度的至少一部分延伸的螺纹（8），用于与过滤器。

3. 发明申请

WO2006113987A1 SYSTEM FOR DEVELOPMENT OF INDIVIDUALISED TREATMENT REGIMENS 审中-公开
标题翻译：发展个体化治疗方案制度
公开(公告)号：WO2006113987A1
公开(公告)日：2006-11-02
申请号：PCT/CA2006/000653
申请日：2006-04-25
申请人： CADUCEUS INFORMATION SYSTEMS INC. , DRANITSARIS, George , VINCENT, Mark
发明人： DRANITSARIS, George , VINCENT, Mark
IPC分类号： A61B5/00 , G06F19/00
CPC分类号： G16H50/70 , G06F19/00 , G16H10/20 , G16H50/20 , G16H50/30 , G16H50/50
摘要： A system is provided for facilitating the development of an individualised treatment regimen for a patient based on an evaluation of the risk(s) associated with a disease and/or associated with known treatment options. In order to evaluate these risk(s), the system utilises clinical data from a plurality of patients having the disease in question. The clinical data includes information for each of the plurality of patients relating to the presence, absence and/or severity of one or more negative events. The negative event(s) can be disease-related, for example, a complication such as metastasis of a cancer to bone or the brain, or the negative event(s) can be treatment-related, for example a toxicity associated with the treatment. The system can also include prediction models that allow the probability that a patient will develop a toxicity or complication to be assessed. Methods for developing prediction models are provided.
摘要翻译：提供了一种系统，用于基于与疾病相关的风险的评估和/或与已知治疗选择相关联的方式促进针对患者的个体化治疗方案的开发。为了评估这些风险，该系统利用来自患有该疾病的多个患者的临床数据。临床数据包括与一个或多个阴性事件的存在，不存在和/或严重性相关的多个患者中的每一个的信息。阴性事件可以是疾病相关的，例如，诸如癌症对骨或脑的转移的并发症，或者阴性事件可以是治疗相关的，例如与治疗相关的毒性。该系统还可以包括允许患者发生毒性或并发症评估的可能性的预测模型。提供了开发预测模型的方法。

4. 发明申请

WO2004082867A3 CONTINUOUS CASTING INSTALLATION & PROCESS 审中-公开
标题翻译：连续铸造安装和工艺
公开(公告)号：WO2004082867A3
公开(公告)日：2004-11-11
申请号：PCT/GB2004001164
申请日：2004-03-18
申请人： PYROTEK ENGINEERING MATERIALS , VINCENT MARK
发明人： VINCENT MARK
IPC分类号： B22D11/117 , B22D11/119 , B22D41/01 , F27B17/00 , F27D3/14 , F27D11/00 , F27D21/00 , F27D99/00 , B22D41/005 , B22D11/06 , F27B14/06 , F27D23/00 , H05B3/62
CPC分类号： F27D99/0006 , B22D11/117 , B22D11/119 , B22D41/01 , F27B17/00 , F27D3/14 , F27D11/00 , F27D21/0014
摘要： A continuous casting installation includes a furnace (2) for heating metal to a first liquid metal temperature, a degassing unit (4), a filter (6), a heating unit (8) and a casting machine (10). The casting machine (10) includes a pair of casting rollers and a nozzle arranged to deliver liquid metal into a nip between the casting rollers, such that the metal solidifies as it passes through the nip. The heating unit (8) is located between the furnace and the casting machine, and is thermostatically controlled to heat the liquid metal to a second liquid metal temperature.
摘要翻译：一种连铸设备包括用于将金属加热至第一液态金属温度的炉（2），脱气单元（4），过滤器（6），加热单元（8）和浇铸机（10）。铸造机（10）包括一对铸造辊和喷嘴，该喷嘴布置成将液态金属输送到铸造辊之间的辊隙中，使得金属在通过辊隙时凝固。加热单元（8）位于熔炉和铸造机之间，并被恒温控制以加热液态金属至第二液态金属温度。

5. 发明申请

WO2004082867A2 CONTINUOUS CASTING INSTALLATION & PROCESS 审中-公开
标题翻译：连续铸造安装和工艺
公开(公告)号：WO2004082867A2
公开(公告)日：2004-09-30
申请号：PCT/GB2004/001164
申请日：2004-03-18
申请人： PYROTEK ENGINEERING MATERIALS LIMITED , VINCENT, Mark
发明人： VINCENT, Mark
IPC分类号： B22D
CPC分类号： F27D99/0006 , B22D11/117 , B22D11/119 , B22D41/01 , F27B17/00 , F27D3/14 , F27D11/00 , F27D21/0014
摘要： A continuous casting installation includes a furnace (2) for heating metal to a first liquid metal temperature, a degassing unit (4), a filter (6), a heating unit (8) and a casting machine (10). The casting machine (10) includes a pair of casting rollers and a nozzle arranged to deliver liquid metal into a nip between the casting rollers, such that the metal solidifies as it passes through the nip. The heating unit (8) is located between the furnace and the casting machine, and is thermostatically controlled to heat the liquid metal to a second liquid metal temperature.
摘要翻译：连续铸造设备包括用于将金属加热到第一液态金属温度的炉（2），脱气单元（4），过滤器（6），加热单元（8）和浇铸机（10）。铸造机（10）包括一对铸辊和喷嘴，其布置成将液态金属输送到铸辊之间的辊隙中，使得金属在其通过辊隙时固化。加热单元（8）位于炉和铸造机之间，并被恒温控制以将液态金属加热至第二液态金属温度。

6. 发明申请

WO2003093291A3 ANTISENSE OLIGONUCLEOTIDES FOR IDENTIFYING DRUG TARGETS AND ENHANCING CANCER THERAPIES 审中-公开
公开(公告)号：WO2003093291A3
公开(公告)日：2003-11-13
申请号：PCT/CA2003/000610
申请日：2003-05-01
申请人： SARISSA INC. , VINCENT, Mark, D. , KOROPATNICK, D., James , BERG, Randall, W.
发明人： VINCENT, Mark, D. , KOROPATNICK, D., James , BERG, Randall, W.
IPC分类号： C12N15/11
摘要： The present invention provides antisense oligonucleotides useful for identifying drug targets for cancer therapies and for enhancing current cancer therapies. The oligonucleotides of the invention are complementary to thymidylate synthase mRNA and affect expression of at least one other gene. For the enhancement of cancer therapies, such antisense oligonucleotides can be used in conjunction with standard chemotherapeutic agents in order to target thymidylate synthase, as well as other appropriate targets. The antisense oligonucleotides and the methods of the invention constitute improved antisense therapies with application to a variety of cancers.

7. 发明申请

WO2003037318A1 USE OF N,N-DIETHYL-2-[-4-(PHENYLMETHYL)-PHENOXY]ETHANAMINE MONOHYDROCHLORIDE (DPPE) IN CANCER THERAPY 审中-公开
标题翻译： N，N-二乙基-2 - [ - 4-（苯基甲基） - 苯氧基]乙酰胺单盐酸盐（DPPE）在癌症治疗中的应用
公开(公告)号：WO2003037318A1
公开(公告)日：2003-05-08
申请号：PCT/CA2002/001651
申请日：2002-11-01
申请人： VINCENT, Mark
发明人： VINCENT, Mark
IPC分类号： A61K31/138
CPC分类号： A61K31/704 , A61K31/138 , A61K2300/00
摘要： The present invention provides for the use of N,N-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine monohydrochloride (DPPE) in cancer therapy. DPPE is used in the treatment of patients having, or suspected of having, an aggressive cancer. The present invention further provides for the use of DPPE in the treatment of a patient suspected of having an existing cancer, wherein the use follows a surgery for treatment of a primary cancer that is estrogen-receptor negative. Also provided are pharmaceutical compositions comprising DPPE for use in the treatment of patients having, or suspected of having, an aggressive cancer and pharmaceutical kits comprising such compositions.
摘要翻译：本发明提供N，N-二乙基-2- [ - 4-（苯基甲基） - 苯氧基]乙胺单盐酸盐（DPPE）在癌症治疗中的用途。 DPPE用于治疗患有或怀疑患有侵袭性癌症的患者。本发明进一步提供DPPE用于治疗疑似患有现有癌症的患者，其中所述用途遵循用于治疗雌激素受体阴性的原发性癌症的手术。还提供了包含DPPE的药物组合物，其用于治疗患有侵袭性癌症的患者或怀疑具有侵袭性癌症的患者以及包含该组合物的药物试剂盒。

8. 发明申请

WO2012175911A1 METAL TRANSFER DEVICE 审中-公开
标题翻译：金属转移装置
公开(公告)号：WO2012175911A1
公开(公告)日：2012-12-27
申请号：PCT/GB2012/000524
申请日：2012-06-18
申请人： PYROTEK ENGINEERING MATERIALS LIMITED , VINCENT, Mark
发明人： VINCENT, Mark
IPC分类号： B22D41/01 , B22D41/02 , B22D35/04 , C21B7/06
CPC分类号： B22D35/04 , B22D41/01 , B22D41/02 , F27D1/0006 , F27D3/145
摘要： A metal transfer device (1) includes a cast trough body (2) for receiving liquid metal, a heater (4) for heating the trough body, and a filler layer (6) between the trough body and the heater. The filler layer (6) comprises a cast refractory material having a high thermal conductivity.
摘要翻译：金属转移装置（1）包括用于接收液体金属的浇注槽体（2），用于加热槽体的加热器（4）和在槽体和加热器之间的填充层（6）。填料层（6）包括具有高导热性的铸造耐火材料。

9. 发明申请

WO2011043947A3 SENSOR DEPLOYMENT AND RETRIEVAL SYSTEM USING FLUID DRAG FORCE 审中-公开
标题翻译：传感器部署和检索系统使用流体动力
公开(公告)号：WO2011043947A3
公开(公告)日：2011-10-20
申请号：PCT/US2010050368
申请日：2010-09-27
申请人： SCHLUMBERGER CA LTD , SCHLUMBERGER SERVICES PETROL , SCHLUMBERGER HOLDINGS , SCHLUMBERGER TECHNOLOGY BV , PRAD RES & DEV LTD , SCHLUMBERGER TECHNOLOGY CORP , GREENAWAY ROBERT , READ BARRY , WILSON COLIN , WHITEHEAD JONATHAN , VINCENT MARK , SUGIYAMA HITOSHI
发明人： GREENAWAY ROBERT , READ BARRY , WILSON COLIN , WHITEHEAD JONATHAN , VINCENT MARK , SUGIYAMA HITOSHI
IPC分类号： G01V9/00 , E21B47/06 , G01V1/40 , G01V3/18
CPC分类号： E21B23/08
摘要： Methods, apparatus, and systems for deploying and retrieving sensors downhole are provided. The apparatus can include an outer tubular member disposed about one or more inner tubular members coupled to a fluid directional controller. The fluid directional controller may include a housing separating an interior cavity from an external environment of the wellbore. One end of the outer tubular member and at least one end of an inner tubular member may communicate with the interior cavity. The housing may also include a passageway configured to provide fluid communication between the interior cavity and the external environment. A flow control device may selectively facilitate fluid flow through the passageway. Accordingly, a sensor located in the interior cavity may be selectively exposed to fluid from the external environment. Sensors may be deployed by flowing fluid through a particular tubular member in one direction and retrieved by flowing fluid in another direction.
摘要翻译：提供了用于在井下部署和检索传感器的方法，设备和系统。该装置可以包括围绕与流体方向控制器连接的一个或多个内部管状构件设置的外部管状构件。流体方向控制器可以包括将内腔与井眼的外部环境分开的壳体。外部管状构件的一端和内部管状构件的至少一个端部可以与内部空腔连通。壳体还可以包括构造成提供内腔和外部环境之间的流体连通的通路。流量控制装置可以选择性地促进流体流过通道。因此，位于内腔中的传感器可以选择性地暴露于来自外部环境的流体。传感器可以通过使流体沿一个方向流过特定的管状构件并通过使流体沿另一方向流动而被回收。

10. 发明申请

WO2011029024A1 APPARATUS FOR GENERATING A GAS WHICH MAY BE USED FOR STARTUP AND SHUTDOWN OF A FUEL CELL 审中-公开
标题翻译：用于产生可用于燃料电池启动和关闭的气体的装置
公开(公告)号：WO2011029024A1
公开(公告)日：2011-03-10
申请号：PCT/US2010/047850
申请日：2010-09-03
申请人： ROLLS-ROYCE FUEL SYTEMS (US) INC. , VINCENT, Mark, Scotto , BIRMINGHAM, Daniel, P. , DE BELLIS, Crispin, L. , PERNA, Mark, Anthony , RUSH, Gregory, C.
发明人： VINCENT, Mark, Scotto , BIRMINGHAM, Daniel, P. , DE BELLIS, Crispin, L. , PERNA, Mark, Anthony , RUSH, Gregory, C.
IPC分类号： H01M8/18
CPC分类号： H01M8/0612 , B01D53/22 , B01D2256/10 , B01D2257/104 , H01M8/04223 , H01M8/04225 , H01M8/04228 , H01M8/04231 , H01M8/04268 , H01M8/04303 , H01M8/04328 , H01M8/04425 , H01M8/04731 , H01M8/04738 , H01M8/04776 , H01M8/04798 , H01M8/04955 , H01M8/0687 , H01M8/2425 , H01M2008/1293
摘要： The present invention provides a gas generator that may be used for startup and shutdown of a fuel cell. In one non-limiting embodiment, the gas generator may include a nitrogen generator structured to receive air, extract oxygen (O 2 ) from the air and discharge the balance in the form of a nitrogen-rich gas; a merging chamber structured to receive a hydrocarbon fuel and the nitrogen-rich gas and to discharge a feed mixture containing both the hydrocarbon fuel and the nitrogen-rich gas; and a catalytic reactor structured to receive the feed mixture and to catalytically convert the feed mixture into a reducing gas.
摘要翻译：本发明提供一种可用于燃料电池的起动和关闭的气体发生器。在一个非限制性实施例中，气体发生器可以包括氮气发生器，其构造成接收空气，从空气中提取氧气（O 2）并以富氮气体的形式排出余量; 合并室，其构造成接收烃燃料和富氮气体并排出含有烃燃料和富氮气体的进料混合物; 以及催化反应器，其被构造成接收进料混合物并将进料混合物催化转化成还原气体。

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