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1. 发明申请

WO2004027377A3 ELECTROACTIVE MICROSPHERES AND METHODS 审中-公开
标题翻译：电活性微球和方法
公开(公告)号：WO2004027377A3
公开(公告)日：2004-09-23
申请号：PCT/US0329029
申请日：2003-09-19
申请人： UNIV NEW MEXICO STATE TECH TRA , WANG JOSEPH , POLSKY RONEN , TURNER KATHRYN L
发明人： WANG JOSEPH , POLSKY RONEN , TURNER KATHRYN L
IPC分类号： G01N33/543 , G01N33/553 , G01N33/53 , G01N21/00 , G01N21/76 , G01N33/533 , G01N33/536 , G01N33/538
CPC分类号： G01N33/54346 , C12Q1/6825 , G01N33/54326 , G01N33/553 , Y10S436/801 , Y10S436/805 , Y10S436/81 , Y10S436/815 , C12Q2537/125 , C12Q2563/116 , C12Q2563/149
摘要： Methods and devices for electrochemical detection of a specific binding pair member utilizing a microsphere with an incorporated electroactive marker, wherein a member of the specific binding pair to be detected is bound, directly or through one or more intermediates, to the microsphere. Multiple specific binding pair members may be detected by use of electrochemically distinguishable electroactive markers. Microspheres with incorporated electroactive markers may include one or more functional groups for binding members of specific binding pairs, and are preferably insoluble in aqueous solvents but soluble in selected organic solvents.
摘要翻译：使用具有引入的电活性标记的微球体特异性结合对成员的电化学检测的方法和装置，其中要检测的特异性结合对的成员直接或通过一个或多个中间体结合到微球体。可以通过使用电化学上可区分的电活性标记来检测多个特异性结合对成员。具有引入的电活性标记的微球可以包括用于结合特异性结合对成员的一个或多个官能团，并且优选不溶于水性溶剂，但可溶于选定的有机溶剂。

2. 发明申请

WO02086077A2 CO-EXPRESSION OF ZEIN PROTEINS 审中-公开
标题翻译： IN蛋白的共表达
公开(公告)号：WO02086077A2
公开(公告)日：2002-10-31
申请号：PCT/US0212646
申请日：2002-04-18
申请人： UNIV NEW MEXICO STATE TECH TRA , KEMP JOHN D , RANDALL JENNIFER J
发明人： KEMP JOHN D , RANDALL JENNIFER J
IPC分类号： C07K14/425 , C12N15/62 , C12N15/82 , C12N
CPC分类号： C12N15/62 , C07K14/425 , C07K2319/02 , C12N15/8251
摘要： Methods and constructs for transformed plants and plant tissues that are capable of expressing high levels of stable proteins localized as protein bodies within the plant cell. Transformed plants co-expressing high levels of both the 15 kD and 10 kD zein proteins are disclosed which accumulate to high levels as protein bodies in the vegetative tissue of the plant. Transformed plants co-expressing the 15 kD and 10 kD zein proteins are useful for providing forage crops containing increased levels of sulfur containing amino acids, such as methionine, in the diet of animals that normally feed on such crops. In one embodiment, a stable protein body is expressed in a plant or plant tissue as a fusion protein comprising both the 15 kD and 10 kD zein proteins operably linked by a polypeptide or peptide linker. The protein bodies provided in the present invention are resistant to rumin digestion or environmental degradation.
摘要翻译：能够表达高水平的稳定蛋白质的转化植物和植物组织的方法和构建体，其定位为植物细胞内的蛋白质体。公开了共表达高水平的15kD和10kD玉米醇溶蛋白的转化植物，其在植物的营养组织中作为蛋白质体累积到高水平。共同表达15kD和10kD玉米醇溶蛋白的转化植物可用于在通常饲养这种作物的动物的饮食中提供含有含量高的含硫氨基酸（例如甲硫氨酸）的饲料作物。在一个实施方案中，稳定的蛋白质体在作为融合蛋白的植物或植物组织中表达，所述融合蛋白包含通过多肽或肽接头可操作地连接的15kD和10kD的玉米醇溶蛋白。在本发明中提供的蛋白质体对抗紫苏消化或环境降解是有抗性的。

3. 发明申请

WO02071013B1 OPTICAL DEVICES AND METHODS EMPLOYING NANOPARTICLES, MICROCAVITIES, AND SEMICONTINUOUS METAL FILMS 审中-公开
标题翻译：采用纳米颗粒，微量元素和半金属膜的光学器件和方法
公开(公告)号：WO02071013B1
公开(公告)日：2003-02-13
申请号：PCT/US0206277
申请日：2002-03-01
申请人： UNIV NEW MEXICO STATE TECH TRA , ARMSTRONG ROBERT L , SHALAEV VLADIMIR M , SMITH HAROLD V , SARYCHEV ANDREY K , YING Z CHARLES
发明人： ARMSTRONG ROBERT L , SHALAEV VLADIMIR M , SMITH HAROLD V , SARYCHEV ANDREY K , YING Z CHARLES
IPC分类号： B82B1/00 , G01J3/44 , G01N21/64 , G01N21/65 , G01N21/76
CPC分类号： G01N21/658 , B82Y10/00 , B82Y20/00 , G01J3/44 , G01N2021/655
摘要： An optical sensing enhancing material (and corresponding method of making) comprising: a medium, the medium comprising a plurality of aggregated nanoparticles (32) comprising fractals; and a microcavity (44), wherein the medium is located in a vicinity of the microcavity. Also an optical sensor and sensing method comprising: providing a doped medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals, with the material; locating the doped medium in the vicinity of a microcavity; exciting the doped medium with a light source; and detecting light reflected from the doped medium. Also an optical sensing enhancing material comprising a medium, the medium comprising a semicontinuous metal film of randomly distributed metal particles and their clusters at approximately their percolation threshold. The medium preferably additionally comprises a microcavity/microresonator. Also devices and methods employing such material.
摘要翻译：一种光学感测增强材料（和相应的制备方法），包括：介质，所述介质包括多个包含分形的聚集的纳米颗粒（32）; 和微腔（44），其中介质位于微腔附近。还有一种光学传感器和感测方法，包括：提供掺杂介质，所述介质包含多个包含分形的聚集的纳米颗粒与所述材料; 将掺杂介质定位在微腔附近; 用光源激发掺杂介质; 以及检测从掺杂介质反射的光。还有一种包括介质的光学感测增强材料，所述介质包括大致其渗透阈值处的随机分布的金属颗粒及其簇的半连续金属膜。该介质优选地另外包括微腔/微谐振器。也是采用这种材料的装置和方法。

4. 发明申请

WO02086557A3 PLASMONIC NANOPHOTONICS METHODS, MATERIALS, AND APPARATUSES 审中-公开
标题翻译： PLASMONIC NANOPHOTONICS方法，材料和装置
公开(公告)号：WO02086557A3
公开(公告)日：2003-02-27
申请号：PCT/US0213033
申请日：2002-04-25
申请人： UNIV NEW MEXICO STATE TECH TRA , SARYCHEV ANDREY K , PODOLSKIY VIKTOR A , DYKHNE ALEXANDER M , SHALAEV VLADIMIR M
发明人： SARYCHEV ANDREY K , PODOLSKIY VIKTOR A , DYKHNE ALEXANDER M , SHALAEV VLADIMIR M
IPC分类号： G01N21/35 , G01N21/55 , G02F1/19 , G02F1/35 , G02F3/00 , G02F1/295 , H01S3/08
CPC分类号： G02B1/007 , B82Y20/00 , G01N21/554 , G01N2021/3568 , G02F1/195 , G02F1/3515 , G02F3/00 , G02F2202/36 , G02F2203/10
摘要： Controlling, guiding, manipulating, and circuiting light and performing surface-enhanced spectroscopy in a medium comprising plasmonic nanomaterials via the excitation of plasmon modes in the materials. The plasmonic nanomaterials are based on metal films with or without arrays of nanoholes and/or on metal nanowires and/or spheroids. Also devices and methods employing such plasmonic nanomaterials.
摘要翻译：通过在材料中激发等离子体激发模式，在包含等离子体激元纳米材料的介质中控制，引导，操纵和电路化光并进行表面增强光谱。等离子体激元纳米材料基于具有或不具有纳米孔阵列和/或金属纳米线和/或球体的金属膜。也是使用这种等离子体激元纳米材料的装置和方法。

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