专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010064208A3 MSP2 ANTIGENIC PEPTIDES AND THEIR USE 审中-公开
标题翻译： MSP2抗原肽及其使用
公开(公告)号：WO2010064208A3
公开(公告)日：2010-07-29
申请号：PCT/IB2009055487
申请日：2009-12-03
申请人： UNIV LAUSANNE , SWISS TROPICAL AND PUBLIC HEAL , CORRADIN GIAMPIETRO , FELGER INGRID
发明人： CORRADIN GIAMPIETRO , FELGER INGRID
IPC分类号： C07K14/445 , A61K39/015 , C07K16/20 , G01N33/569
CPC分类号： C07K14/445 , A61K39/00 , G01N33/56905 , G01N2333/445 , G01N2469/10 , G01N2469/20
摘要： This invention relates generally to the field of P. falciparum antigens and their use, for example, for the preparation of a vaccine against said pathogen. More specifically, the present invention relates to an antigenic peptide derived from the constant part of MSA2, and includes antibodies and methods of producing and using same.
摘要翻译：本发明一般涉及恶性疟原虫抗原的领域及其用于制备针对所述病原体的疫苗的用途。更具体地，本发明涉及源自MSA2的恒定部分的抗原肽，并且包括抗体及其制备和使用方法。

2. 发明申请

WO2007004045A3 USE OF A PHOTOSENSITIZING AGENT IN THE TREATMENT OR PREVENTION OF AN INFLAMMATION-ASSOCIATED DISORDER IN THE GASTROINTESTINAL TRACT OF A MAMMAL 审中-公开
公开(公告)号：WO2007004045A3
公开(公告)日：2007-03-29
申请号：PCT/IB2006001857
申请日：2006-07-05
申请人： UNIV LAUSANNE , ORTNER MARIA-ANNA , MICHETTI PIERRE , VELIN DOMINIQUE
发明人： ORTNER MARIA-ANNA , MICHETTI PIERRE , VELIN DOMINIQUE
IPC分类号： A61K41/00
CPC分类号： A61K41/0061
摘要： The present invention relates generally to the field of Photodynamic therapy (PDT) and more particularly to the use of a photosensitizing agent for the preparation of a medicament for the treatment or prevention of an inflammation-associated disorder in the gastrointestinal tract of a mammal, wherein the expression of pro-inflammatory markers in a tissue of said gastrointestinal tract is decreased after administering said photosensitizing agent to said tissue and exposing said tissue to a light having a wavelength absorbed by said photosensitizing agent.

3. 发明申请

WO2004091646A3 USE OF SLURP-1 FOR TREATING DISEASES RELATED TO ACETYLCHOLINE RECEPTORS DYSFUNCTION 审中-公开
标题翻译：使用SLURP-1治疗与乙酰胆碱受体相关的疾病
公开(公告)号：WO2004091646A3
公开(公告)日：2004-12-16
申请号：PCT/IB2004001716
申请日：2004-04-16
申请人： UNIV LAUSANNE , UNIV GENEVE , CHIMIENTI FABRICE , HOGG RONALD , HUBER MARCEL , BERTRAND DANIEL , HOHL DANIEL
发明人： CHIMIENTI FABRICE , HOGG RONALD , HUBER MARCEL , BERTRAND DANIEL , HOHL DANIEL
IPC分类号： A61K38/17 , A61P17/02 , A61P17/06 , A61P25/00 , G01N33/68 , G01N33/94 , A61K39/395 , G01N33/50
CPC分类号： G01N33/6896 , A61K38/177 , G01N33/6881 , G01N33/944 , G01N2333/4719 , G01N2500/00
摘要： Disclosed herein is the use of SLURP-1 for the treatment or prevention of neurological disorders,and for the treatment or prevention of skin pathologies.The invention further discloses the use of SLURP-1 for the modulation of acetylcholine receptor activity.Antibodies generated against SLURP-1 and related proteins are also disclosed.
摘要翻译：本文公开了SLURP-1用于治疗或预防神经系统疾病以及治疗或预防皮肤病理学的用途。本发明还公开了SLURP-1用于调节乙酰胆碱受体活性的用途。针对SLURP产生的抗体 -1和相关蛋白质也被公开。

4. 发明申请

WO2004046183A3 IDENTIFICATION OF AN AGONIST-V1R RECEPTOR PAIR FUNCTIONAL IN THE OLFACTORY SYSTEM AND USES THEREOF 审中-公开
标题翻译： OLFACTORY系统中激动剂V1R受体对功能的鉴定及其应用
公开(公告)号：WO2004046183A3
公开(公告)日：2004-11-11
申请号：PCT/IB0306307
申请日：2003-11-17
申请人： UNIV GENEVE , RODRIQUEZ IVAN , BROILLET MARIE-CHRISTINE , UNIV LAUSANNE
发明人： RODRIQUEZ IVAN , BROILLET MARIE-CHRISTINE
IPC分类号： C07K14/705 , G01N33/50
CPC分类号： C07K14/705
摘要： The present invention provides an agonist (2-heptanone) to a mouse receptor encoded by a vomeronasal receptor (vlrb2) nucleic acid. The invention includes methods for general activation of Vlr-expressing sensory neurons in mammals, using a forced expression of the mouse v1rb2 receptor, in order to elicit specific behavioral and/or endocrine reactions. The invention further provides compositions comprising the receptor-agonist pair and methods for their use in identifying further receptors, agonists, antagonists, and modulators of vomeronasal receptor mediated biochemical, cellular, and behavioral responses.
摘要翻译：本发明提供了由犁鼻受体（vlrb2）核酸编码的小鼠受体激动剂（2-庚酮）。本发明包括使用小鼠v1rb2受体的强制表达来通用激活哺乳动物中表达Vlr的感觉神经元以引发特异性行为和/或内分泌反应的方法。本发明进一步提供了包含受体 - 激动剂对的组合物及其用于鉴定犁鼻器受体介导的生物化学，细胞和行为反应的其他受体，激动剂，拮抗剂和调节剂的方法。

5. 发明申请

WO0230258A3 TARGETING SYSTEM AND METHOD FOR DISTAL LOCKING OF INTRAMEDULLAR NAILS 审中-公开
标题翻译：用于远端锁定内钉的钉扎系统和方法
公开(公告)号：WO0230258A3
公开(公告)日：2004-05-27
申请号：PCT/IB0102731
申请日：2001-10-12
申请人： UNIV LAUSANNE , ARLETTAZ YVAN
发明人： ARLETTAZ YVAN
IPC分类号： A61B17/17
CPC分类号： A61B17/1725
摘要： A targeting system and method is disclosed for the distal locking of intramedullary nails. The targeting system comprises a first fixation system, a second fixation system, and an aiming guide. After implantation within the intramedullary canal of a bone, the distal screw holes of an intramedullary nail are first aligned using conventional radioscopy equipment. The targeting system is then introduced between the radioscopy equipment and the patient such that the aiming guide of the targeting system is roughly aligned with the distal screw holes. The first fixation system is adapted to be fixedly coupled to an operating surface upon which an intramedullary nail fixation procedure may be performed. The second fixation system is adapted to be fixedly coupled to the handle of the implanted intramedullary nail. Rough adjustments to the first and second fixation systems enable an initial positioning of a drill with a first distal screw hole. The aiming guide, which is disposed between and fixedly coupled to the first fixation system and the second fixation system, is used to perfect alignment of the drill with the first distal screw hole. Once a precise alignment with the first distal screw hole has been realized, a mechanical adjustment to the aiming guide may allow for a rapid alignment of the drill with the second distal screw hole of the implanted intramedullary nail.
摘要翻译：公开了用于髓内钉远端锁定的靶向系统和方法。瞄准系统包括第一固定系统，第二固定系统和瞄准指南。在骨髓内髓内植入后，首先使用常规的放射检查设备对准髓内钉的远端螺钉孔。然后将靶向系统引入到放射检查设备和患者之间，使得瞄准系统的瞄准引导件与远端螺钉孔大致对准。第一固定系统适于固定地联接到可以在其上执行髓内钉固定过程的操作表面。第二固定系统适于固定地联接到植入的髓内钉的手柄。对第一和第二固定系统的粗略调整使得能够初始定位具有第一远端螺钉孔的钻孔。设置在第一固定系统和第二固定系统之间并固定地联接到第一固定系统和第二固定系统之间的瞄准引导件用于完善钻头与第一远端螺钉孔的对准。一旦已经实现了与第一远端螺钉孔的精确对准，对瞄准引导件的机械调节可允许钻头与植入的髓内钉的第二远端螺钉孔的快速对准。

6. 发明申请

WO0152753A8 HIGH PERFORMANCE CANNULAS 审中-公开
标题翻译：高性能肛门
公开(公告)号：WO0152753A8
公开(公告)日：2001-09-27
申请号：PCT/IB0100191
申请日：2001-01-18
申请人： UNIV LAUSANNE , VON SEGESSER LUDWIG K
发明人： VON SEGESSER LUDWIG K
IPC分类号： A61B17/00 , A61B17/34 , A61M25/00
CPC分类号： A61M25/0023 , A61B17/3431 , A61B17/3439
摘要： Provided is a high performance cannula having a proximal end, a distal end, and a lumen extending between the proximal and distal ends, wherein the diameter of the lumen of the cannula can be varied to take into account differences in the diameter of access and target vessels during cannulation. The cannula is characterized by a narrow diameter at the point of insertion that does not adversely impact the flow rate of fluids through the cannula. The cannulas according to this invention produce a small access aperture and are characterized by flow rates that are at least as effective as those of conventional cannulas that produce larger access apertures.
摘要翻译：提供了一种具有近端，远端和在近端和远端之间延伸的内腔的高性能插管，其中套管的内腔的直径可以变化以考虑入口直径和目标的差异插管期间的血管套管的特征在于在插入点处的窄直径，其不会不利地影响通过套管的流体的流速。根据本发明的插管产生小的进入孔，并且其特征在于至少与产生较大进入孔的常规插管同样有效的流速。

7. 发明申请

WO2009093213A3 METHOD FOR PREDICTING AND DIAGNOSING BRAIN TUMOR 审中-公开
标题翻译：预测和诊断脑肿瘤的方法
公开(公告)号：WO2009093213A3
公开(公告)日：2010-04-08
申请号：PCT/IB2009050279
申请日：2009-01-23
申请人： UNIV LAUSANNE , HEGI MONIKA , MURAT ANASTASIA , MIGLIAVACCA EUGENIA , STUPP ROGER
发明人： HEGI MONIKA , MURAT ANASTASIA , MIGLIAVACCA EUGENIA , STUPP ROGER
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/154 , C12Q2600/158
摘要： The present invention relates to a method for predicting or diagnosing outcome of concomitant chemo-radiotherapy of a subject suffering from brain tumor. The present invention further relates to compositions and methods for treatment or prevention of tumor resistance in a subject suffering from a brain tumor and to a kit useful for predicting or diagnosing the tumor resistance in a subject treated with concomitant chemo-radiotherapy.
摘要翻译：本发明涉及用于预测或诊断患有脑肿瘤的受试者的伴随化学放疗结果的方法。本发明还涉及用于治疗或预防患有脑肿瘤的受试者的肿瘤抗性的组合物和方法，以及可用于预测或诊断用伴随的化学放疗治疗的受试者中的肿瘤抗性的试剂盒。

8. 发明申请

WO2009098656A3 METHOD FOR PREDICTING OR DIAGNOSING OUTCOME OF INTRACRANIAL TUMORS IN A SUBJECT 审中-公开
标题翻译：预测或诊断受试者颅内肿瘤结局的方法
公开(公告)号：WO2009098656A3
公开(公告)日：2009-10-01
申请号：PCT/IB2009050479
申请日：2009-02-05
申请人： UNIV LAUSANNE , DESBAILLETS HAKIMI ISABELLE , HEGI MONIKA
发明人： DESBAILLETS HAKIMI ISABELLE , HEGI MONIKA
IPC分类号： G01N33/574 , C07K14/475
CPC分类号： G01N33/57488 , G01N2333/495
摘要： The present invention relates to a method for diagnosing or predicting outcome of intracranial tumors in the cerebrospinal fluid of a subject. The present invention further relates to compositions and methods for treatment or prevention of intracranial tumors in a subject and to a kit useful for predicting same.
摘要翻译：本发明涉及用于诊断或预测受试者脑脊液中颅内肿瘤结局的方法。本发明进一步涉及用于治疗或预防受试者颅内肿瘤的组合物和方法，以及可用于预测其的颅内肿瘤的试剂盒。

9. 发明申请

WO2009074969A2 SPHINGOSINE-1-PHOSPHATE, ANALOGS AND ANTAGONISTS FOR USE AS MEDICAMENTS 审中-公开
标题翻译： SPHINGOSINE-1-PHOSPHATE，ANALOGS AND ANTAGONISTS FOR US MEDICAMENTS
公开(公告)号：WO2009074969A2
公开(公告)日：2009-06-18
申请号：PCT/IB2008055253
申请日：2008-12-12
申请人： UNIV LAUSANNE , BRAKCH NOUREDDINE , BARBEY FREDERIC , HAYOZ DANIEL JEAN-LOUIS
发明人： BRAKCH NOUREDDINE , BARBEY FREDERIC , HAYOZ DANIEL JEAN-LOUIS
IPC分类号： A61K31/00 , A61K31/135 , A61K31/381 , A61K31/4245 , A61K31/437 , A61K31/661 , A61K31/662 , A61K38/47 , A61K45/06 , A61P3/00 , A61P9/00 , A61P9/06 , A61P9/10 , G01N33/92
CPC分类号： A61K31/661 , A61K31/00 , A61K31/135 , A61K31/381 , A61K31/4245 , A61K31/437 , A61K31/662 , A61K38/47 , A61K45/06 , G01N33/92 , G01N2500/04 , G01N2800/044 , G01N2800/32 , G01N2800/323 , A61K2300/00
摘要： The present invention relates to compounds for treating and/or preventing cardiac and/or vascular symptoms in individuals suffering from Fabry disease. More generally, the present invention relates to compounds treating and/or preventing vascular and/or cardiac hypertrophy and/or hyperplasia, in particular in smooth muscle tissue / cells, such as vascular smooth muscle tissue. The present invention uses antagonists of sphingosine-1 -phosphate (SlP) for treating cardiac and vascular hypertrophy and/or hyperplasia, and SlP and its agonists for treating and/or preventing atherosclerosis.
摘要翻译：本发明涉及用于治疗和/或预防患有法布里病的个体的心脏和/或血管症状的化合物。更一般来说，本发明涉及治疗和/或预防血管和/或心脏肥大和/或增生的化合物，特别是在平滑肌组织/细胞如血管平滑肌组织中。本发明使用鞘氨醇-1-磷酸拮抗剂（S1P）治疗心脏和血管肥大和/或增生，以及S1P及其激动剂用于治疗和/或预防动脉粥样硬化。

10. 发明申请

WO2008118469A3 GENETICS VARIANTS ASSOCIATED WITH HIV DISEASE RESTRICTION 审中-公开
标题翻译：与HIV感染相关的遗传学变异
公开(公告)号：WO2008118469A3
公开(公告)日：2008-12-24
申请号：PCT/US2008003964
申请日：2008-03-27
申请人： UNIV DUKE , UNIV LAUSANNE , GOLDSTEIN DAVID B , TELENTI AMALIO , FELLAY JACQUES , SHIANNA KEVIN V , GE DONGLIANG , HAYNES BARTON F
发明人： GOLDSTEIN DAVID B , TELENTI AMALIO , FELLAY JACQUES , SHIANNA KEVIN V , GE DONGLIANG , HAYNES BARTON F
IPC分类号： C12Q1/68 , C07H21/02
CPC分类号： C12Q1/703 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158
摘要： The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to genetic variants associated with restriction of HIV disease progression.
摘要翻译：本发明一般涉及人类免疫缺陷病毒（HIV），并且特别涉及与限制HIV疾病进展有关的遗传变异体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式