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1. 发明申请

WO2009085459A1 FLEXIBLE POLYMER ELECTRODE FOR MRI-GUIDED POSITIONING AND RADIO FREQUENCY ABLATION 审中-公开
标题翻译：用于MRI引导定位和无线电频率消除的柔性聚合物电极
公开(公告)号：WO2009085459A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/084203
申请日：2008-11-20
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , PAUL, Saurav , TEGG, Troy T. , THAO, Chou , PURYEAR, Harry
发明人： PAUL, Saurav , TEGG, Troy T. , THAO, Chou , PURYEAR, Harry
IPC分类号： A61B18/24
CPC分类号： A61B18/1492 , A61B5/055 , A61B5/06 , A61B2018/00702 , A61B2018/00791 , A61B2018/00815 , A61B2034/2068 , A61B2090/374 , A61B2090/3954
摘要： An electrode for use on a medical device is disclosed. The electrode (12) may have a main body (14) of electrically conductive material extending along an axis (16) and may have a proximal end (20) and a distal end (18). The electrode (12) may also include a magnetic resonance imaging (MRI) tracking coil (32) disposed in the body (14). The MRI tracking coil (32) may comprise electrically insulated wire. A catheter (10) including an electrode (12), as well as a method for determining the location of an electrode (12), are also disclosed.
摘要翻译：公开了一种用于医疗装置的电极。电极（12）可以具有沿着轴线（16）延伸的导电材料的主体（14），并且可以具有近端（20）和远端（18）。电极（12）还可以包括设置在主体（14）中的磁共振成像（MRI）跟踪线圈（32）。 MRI跟踪线圈（32）可以包括电绝缘线。还公开了包括电极（12）的导管（10）以及用于确定电极（12）的位置的方法。

2. 发明申请

WO2007067941A3 ASSESSMENT OF ELECTRODE COUPLING FOR TISSUE ABLATION 审中-公开
公开(公告)号：WO2007067941A3
公开(公告)日：2008-11-20
申请号：PCT/US2006061714
申请日：2006-12-06
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , PAUL SAURAV , BELHE KEDAR RAVINDRA , CAO HONG , THAO CHOU
发明人： PAUL SAURAV , BELHE KEDAR RAVINDRA , CAO HONG , THAO CHOU
IPC分类号： A61B18/18
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.

3. 发明申请

WO2008083122A3 PRESSURE-SENSITIVE CONDUCTIVE COMPOSITE ELECTRODE AND METHOD FOR ABLATION 审中-公开
标题翻译：压敏导电性复合电极及消融方法
公开(公告)号：WO2008083122A3
公开(公告)日：2008-09-18
申请号：PCT/US2007088723
申请日：2007-12-21
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , PAUL SAURAV , BELHE KEDAR RAVINDRA , THAO CHOU , CAO HONG
发明人： PAUL SAURAV , BELHE KEDAR RAVINDRA , THAO CHOU , CAO HONG
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2018/00791 , A61B2018/1437 , A61B2090/064 , A61B2090/065 , A61B2218/002
摘要： The present invention is directed to ablation devices and methods utilizing pressure sensitive conductive composites, such as quantum tunneling composites, or other contact-sensitive, conductive polymers. The materials provide for electrodes and methods capable of differentiating between a soft and a hard push. The present invention thus provides an electrode for delivering selective electrical energy for ablation that may be varied based upon the pressure exerted on the surface area of the targeted tissue.
摘要翻译：本发明涉及利用压敏导电复合材料（例如量子隧穿复合材料）或其他接触敏感的导电聚合物的消融设备和方法。这些材料提供了能够区分软推和硬推的电极和方法。因此，本发明提供了用于传递选择性电能以用于消融的电极，其可以基于施加在目标组织的表面区域上的压力而变化。

4. 发明申请

WO2008082803A2 ABLATION CATHETER WITH THERMALLY MEDIATED CATHETER BODY FOR MITIGATING BLOOD COAGULATION AND CREATING LARGER LESION 审中-公开
标题翻译：具有热介质导管体的吸引管，用于减轻血液凝结和产生大量损伤
公开(公告)号：WO2008082803A2
公开(公告)日：2008-07-10
申请号：PCT/US2007/084690
申请日：2007-11-14
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIV., INC. , PAUL, Saurav , CAO, Hong , GUO, Xiaoping , SHAI, Isaac , YANG, Michael , BELHE, Kedar Ravindra , THAO, Chou
发明人： PAUL, Saurav , CAO, Hong , GUO, Xiaoping , SHAI, Isaac , YANG, Michael , BELHE, Kedar Ravindra , THAO, Chou
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/00005 , A61B2018/00357
摘要： An ablation catheter (10) is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode (22) is connected relative to the distal end of the catheter (10) for providing ablation energy to patient tissue. A heat sink (40) is provided that is in thermal contact with the ablation electrode (22). The heat sink (40), in addition to being in thermal contact with the ablation electrode (22), is electrically isolated from the ablation electrode (22). This allows the heat sink (40) to conduct heat away from the ablation electrode (22) without dissipating electrical energy from the electrode (22). In this regard, the heat sink (40) may prevent build-up of excess heat within the electrode (22) that may result in blood coagulation and/or tissue charring.
摘要翻译：提供消融导管（10），用于烧蚀患者的内部组织。该导管包括适于相对于其中的期望位置（例如，在心脏内）插入体腔中的远端。消融电极（22）相对于导管（10）的远端连接，用于向患者组织提供消融能量。提供与消融电极（22）热接触的散热器（40）。除了与消融电极（22）热接触之外，散热器（40）与消融电极（22）电隔离。这允许散热器（40）将热量从消融电极（22）导出，而不会从电极（22）中消散电能。在这方面，散热器（40）可防止可能导致血液凝固和/或组织烧焦的电极（22）内的过多热量的累积。

5. 发明申请

WO2007050960A3 SYSTEMS AND METHODS FOR ELECTRODE CONTACT ASSESSMENT 审中-公开
标题翻译：用于电极接触评估的系统和方法
公开(公告)号：WO2007050960A3
公开(公告)日：2007-12-06
申请号：PCT/US2006042119
申请日：2006-10-27
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , PAUL SAURAV , TEGG TROY , THAO CHOU , CAO HONG , PURYEAR HARRY , KUEHN FOS , HEIMBECHER REED R
发明人： PAUL SAURAV , TEGG TROY , THAO CHOU , CAO HONG , PURYEAR HARRY , KUEHN FOS , HEIMBECHER REED R
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2090/065
摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode 10 housed within a distal portion of a catheter shaft 14. At least one electro-mechanical sensor 20 is operatively associated with the electrode 10 within the catheter shaft 14. The at least one electro-mechanical sensor 20 is responsive to movement of the electrode 10 by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electro-mechanical sensor 20. The output device receives the electrical signals for assessing a level of contact between the electrode 10 and a tissue 12.
摘要翻译：公开了用于评估用于组织消融的电极 - 组织接触的系统和方法。示例性电极接触感测系统包括容纳在导管轴14的远侧部分内的电极10.至少一个机电传感器20与导管轴14内的电极10操作性地关联。至少一个机电传感器 20响应于电极10的移动，通过产生对应于移动量的电信号。系统还可以包括电连接到至少一个机电传感器20的输出设备。输出设备接收电信号以评估电极10和组织12之间的接触水平。

6. 发明申请

WO2007002004A2 ABLATION CATHETER WITH FLUID DISTRIBUTION STRUCTURES 审中-公开
标题翻译：具有流体分布结构的吸引管
公开(公告)号：WO2007002004A2
公开(公告)日：2007-01-04
申请号：PCT/US2006023854
申请日：2006-06-19
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , CAO HONG , THAO CHOU , BELHE KEDAR RAVINDRA , PAUL SAURAV , STANGENES TODD
发明人： CAO HONG , THAO CHOU , BELHE KEDAR RAVINDRA , PAUL SAURAV , STANGENES TODD
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00375 , A61B2018/1472
摘要： An ablation catheter (22) has improved fluid distribution structures. An ablation section at a distal end (12) of the catheter (22) is designed to provide a more uniform fluid flow emanating from the catheter (22). By creating a uniform fluid flow, a more uniform tissue lesion results and the possibility of charring the tissue is reduced. A combination of mesh material (142) layers, porous materials (354), and dispersion channels or openings (346) are used to achieve the uniform flow. The amount of fluid used as a virtual electrode to ablate the tissue is greatly reduced with the present invention. Further, the catheter (22) may be used to create a single, uniform linear lesion by successive application of energy to adjacent portions of the ablation section, thus reducing the power required to create the desired lesion.
摘要翻译：消融导管（22）具有改进的流体分布结构。在导管（22）的远端（12）处的消融部分被设计成提供从导管（22）发出的更均匀的流体流。通过产生均匀的流体流动，会产生更均匀的组织损伤，并且减少了烧结组织的可能性。使用网状材料（142）层，多孔材料（354）和分散通道或开口（346）的组合来实现均匀的流动。用于消融组织的虚拟电极的流体量大大减少。此外，导管（22）可以用于通过将能量连续施加到消融部分的相邻部分来产生单一的均匀的线性损伤，从而减少产生所需损伤所需的功率。

7. 发明申请

WO2005072488A2 BRUSH ELECTRODE AND METHOD FOR ABLATION 审中-公开
标题翻译： BRUSH电极和方法
公开(公告)号：WO2005072488A2
公开(公告)日：2005-08-11
申请号：PCT/US2005/000767
申请日：2005-01-14
申请人： ST. JUDE MEDICAL, DAIG DIVISION, INC. , PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
发明人： PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/143 , A61B2018/1472
摘要： A brush electrode ( e.g ., 10) and a method for using the brush electrode for tissue ablation are disclosed. The brush electrode comprises a plurality of flexible filaments or bristles ( e.g ., 26) for applying ablative energy to target tissue (46) during the formation of spot or continuous linear lesions. Interstitial spaces (156) are defined among the filaments of the brush electrode, and the interstitial spaces are adapted to direct conductive or nonconductive fluid (34), when present, toward the distal ends of the brush filaments. The brush electrode facilitates electrode tissue contact in target tissue having flat or contoured surfaces. The flexible filaments may be selectively trimmed to give a desired tip configuration or a desired standoff distance between the tissue and the conductive filaments in the brush electrode. Also, the filaments may be grouped into clusters. A shielded tip brush electrode ( e.g ., 120), including a flexible boot ( e.g ., 142), is also disclosed.
摘要翻译：公开了一种刷电极（例如，10）和用于组织消融的刷电极的使用方法。刷电极包括多个柔性细丝或刷毛（例如26），用于在形成斑点或连续线性病变期间向靶组织（46）施加烧蚀能量。间隙空间（156）被限定在刷电极的长丝之间，并且间隙空间适于使导电或非导电流体（34）当存在时朝向刷丝的远端引导。刷电极有助于在具有平坦或轮廓的表面的靶组织中的电极组织接触。可以选择性地修剪柔性细丝以给出组织和刷电极中的导电细丝之间的期望的尖端构型或期望的间隔距离。此外，丝可以分组成簇。还公开了一种包括柔性靴（例如142）的屏蔽尖端刷电极（例如120）。

8. 发明申请

WO2008082803A3 ABLATION CATHETER THERMALL MEDIATED CATHETER BODY 审中-公开
标题翻译：吸引管热介质导管体
公开(公告)号：WO2008082803A3
公开(公告)日：2008-08-21
申请号：PCT/US2007084690
申请日：2007-11-14
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , PAUL SAURAV , CAO HONG , GUO XIAOPING , SHAI ISAAC , YANG MICHAEL , BELHE KEDAR RAVINDRA , THAO CHOU
发明人： PAUL SAURAV , CAO HONG , GUO XIAOPING , SHAI ISAAC , YANG MICHAEL , BELHE KEDAR RAVINDRA , THAO CHOU
IPC分类号： A61B18/04
CPC分类号： A61B18/1492 , A61B2018/00005 , A61B2018/00357
摘要： An ablation catheter (10) is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode (22) is connected relative to the distal end of the catheter (10) for providing ablation energy to patient tissue. A heat sink (40) is provided that is in thermal contact with the ablation electrode (22). The heat sink (40), in addition to being in thermal contact with the ablation electrode (22), is electrically isolated from the ablation electrode (22). This allows the heat sink (40) to conduct heat away from the ablation electrode (22) without dissipating electrical energy from the electrode (22). In this regard, the heat sink (40) may prevent build-up of excess heat within the electrode (22) that may result in blood coagulation and/or tissue charring.
摘要翻译：提供消融导管（10），用于烧蚀患者的内部组织。该导管包括适于相对于其中的期望位置（例如，在心脏内）插入体腔中的远端。消融电极（22）相对于导管（10）的远端连接，用于向患者组织提供消融能量。提供与消融电极（22）热接触的散热器（40）。除了与消融电极（22）热接触之外，散热器（40）与消融电极（22）电隔离。这允许散热器（40）将热量从消融电极（22）导出，而不会从电极（22）中消散电能。在这方面，散热器（40）可防止可能导致血液凝固和/或组织烧焦的电极（22）内的过多热量的累积。

9. 发明申请

WO2008083123A1 DESIGN OF ABLATION ELECTRODE WITH TACTILE SENSOR 审中-公开
标题翻译：消除电极与触觉传感器的设计
公开(公告)号：WO2008083123A1
公开(公告)日：2008-07-10
申请号：PCT/US2007/088729
申请日：2007-12-21
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , CAO, Hong , THAO, Chou , PAUL, Saurav
发明人： CAO, Hong , THAO, Chou , PAUL, Saurav
IPC分类号： A61B5/04
CPC分类号： A61B18/1492 , A61B5/6852 , A61B5/6885 , A61B2090/065
摘要： A catheter assembly for assessing contact between the catheter assembly and tissue is disclosed. The assembly includes a catheter shaft and a pressure sensitive conductive composite member whose electrical resistance varies with pressure applied to the catheter assembly. The assembly also includes at least one measurement terminal to permit the measurement of changes in the electrical characteristics of the pressure sensitive conductive composite member. The assembly may optionally include a measurement device to measure resistance, impedance and/or other electrical characteristics. The assembly may utilize a reference electrode secured to the patient's tissue, which permits the measurement device to measure changes between the reference electrode and the at least one measurement terminal. Optionally, the assembly may include a conductive outer layer. Also disclosed are sensor assemblies, contact sensor, methods of contact sensing, and methods of manufacturing relating to the use of pressure sensitive conductive composites.
摘要翻译：公开了一种用于评估导管组件和组织之间的接触的导管组件。组件包括导管轴和压力敏感的导电复合构件，其电阻随着施加到导管组件的压力而变化。组件还包括至少一个测量端子，以允许测量压敏导电复合构件的电特性的变化。组件可以可选地包括测量电阻，阻抗和/或其他电特性的测量装置。组件可以利用固定到患者组织的参考电极，其允许测量装置测量参考电极和至少一个测量终端之间的变化。可选地，组件可以包括导电外层。还公开了传感器组件，接触传感器，接触感测方法以及与使用压敏导电复合材料有关的制造方法。

10. 发明申请

WO2008045956A3 TISSUE CONTACT AND THERMAL ASSESSMENT FOR BRUSH ELECTRODES 审中-公开
标题翻译：用于布丝电极的组织接触和热评估
公开(公告)号：WO2008045956A3
公开(公告)日：2008-07-10
申请号：PCT/US2007080981
申请日：2007-10-10
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , THAO CHOU , CAO HONG , PAUL SAURAV
发明人： THAO CHOU , CAO HONG , PAUL SAURAV
IPC分类号： A61B5/103
CPC分类号： A61B18/14 , A61B18/1492 , A61B2018/00351 , A61B2018/143 , A61B2090/065
摘要： Systems and methods are disclosed for tissue contact and thermal assessment, e.g., for tis
摘要翻译：公开了用于组织接触和热评估的系统和方法，例如用于tis

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