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1. 发明申请

WO2018115983A1 CALIBRATION APPARATUS AND METHODS FOR CALIBRATING A MEDICAL INSTRUMENT 审中-公开
公开(公告)号：WO2018115983A1
公开(公告)日：2018-06-28
申请号：PCT/IB2017/051604
申请日：2017-03-20
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , KHERADPIR, Leila , DUPONT, Kyle Richard , JANKOWSKI, Jakub , UTHAYANATHAN, Suman
发明人： KHERADPIR, Leila , DUPONT, Kyle Richard , JANKOWSKI, Jakub , UTHAYANATHAN, Suman
IPC分类号： A61B90/10 , A61B5/06 , A61B90/11 , A61B34/30 , A61B34/20
摘要： An apparatus and methods, operable with a medical navigation system, for calibrating a medical tool having a tip, involving a body configured to accommodate a plurality of tool dimensions and having a plurality of cooperating spring-loaded cams for accommodating a plurality of tool cross-sectional dimensions, a frame couple-able with the body and having at least one frame tracking marker coupled therewith, and a reference point feature coupled with the body, the reference point feature providing a known spatial reference point relative to the at least one frame tracking marker.

2. 发明申请

WO2018102904A1 OPTICAL-BASED INPUT FOR MEDICAL DEVICES 审中-公开
公开(公告)号：WO2018102904A1
公开(公告)日：2018-06-14
申请号：PCT/CA2016/051440
申请日：2016-12-08
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , SRIMOHANARAJAH, Kirusha , LUI, Dorothy , SELA, Gal , SOMAN, Stephen Elliott , MOVAGHATI, Sepide
发明人： SRIMOHANARAJAH, Kirusha , LUI, Dorothy , SELA, Gal , SOMAN, Stephen Elliott , MOVAGHATI, Sepide
IPC分类号： A61B34/20 , A61B34/30
摘要： A system for adjusting an operating state of a medical electronic device is described. In an aspect, the system includes an optical tracking system configured to detect three or more tracking markers. The system also includes a processor coupled with the optical tracking system. The processor is programmed with instructions which, when executed, configure the processor to: configure an input command by assigning at least one operating state of the medical electronic device to a particular state of at least one of the tracking markers; after receiving a priming command, identify a present state of the tracking markers based on data from the optical tracking system; compare the present state with the particular state assigned to the operating state; and based on the comparison, determine that an input command has been received and adjust the operating state of the medical electronic device to the assigned operating state.

3. 发明申请

WO2018071999A1 MIXED REALITY TRAINING SYSTEM 审中-公开
标题翻译：混合式现实培训系统
公开(公告)号：WO2018071999A1
公开(公告)日：2018-04-26
申请号：PCT/CA2016/000266
申请日：2016-10-21
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , SELA, Gal , KERINS, Fergal , ABHARI, Kamyar , SRIMOHANARAJAH, Kirusha
发明人： SELA, Gal , KERINS, Fergal , ABHARI, Kamyar , SRIMOHANARAJAH, Kirusha
IPC分类号： G09B23/30 , A61B34/10 , A61B34/20 , G09B9/00
摘要： A training system for training a trainee to perform a surgical procedure on an anatomical region. The system includes a physical model of the anatomical region, a physical training instrument, a tracking system configured to track the location and orientation of the physical training instrument relative to the physical model, a display device, and a computer system. The computer system receives from the tracking system information indicating the location and orientation of the physical training instrument and generates and displays an augmented physical model and the physical training instrument. The display is updated based as the trainee manipulates the physical training instrument. After the trainee has completed the surgical procedure, the computer calculates a score based on the performance of the trainee. The score is a measure of the accuracy of the surgical procedure performed by the trainee or the duration of the surgical procedure.
摘要翻译：
一种训练系统，用于训练学员在解剖区域执行外科手术。该系统包括解剖区域的物理模型，物理训练仪器，被配置为跟踪物理训练仪器相对于物理模型的位置和方向的跟踪系统，显示装置和计算机系统。计算机系统从跟踪系统接收指示身体训练仪器的位置和方向的信息，并生成并显示增强的身体模型和身体训练仪器。根据学员操作物理训练仪器的情况更新显示。学员完成外科手术后，计算机根据受训者的表现计算得分。得分是由受训者进行的外科手术的准确性或外科手术的持续时间的量度。

4. 发明申请

WO2018033775A1 A FLEXIBLE HIGH RESOLUTION ENDOSCOPE 审中-公开
标题翻译：一种灵活的高分辨率内窥镜
公开(公告)号：WO2018033775A1
公开(公告)日：2018-02-22
申请号：PCT/IB2016/054931
申请日：2016-08-17
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , CHEN, Sean Jy-Shyang , ABHARI, Kamyar , WOOD, Michael Frank Gunter , SELA, Gal
发明人： CHEN, Sean Jy-Shyang , ABHARI, Kamyar , WOOD, Michael Frank Gunter , SELA, Gal
IPC分类号： A61B1/04 , A61B1/005 , A61B1/045 , A61B1/07
CPC分类号： A61B1/045 , A61B1/005 , A61B1/0051 , A61B1/01 , A61B1/04 , A61B1/0676 , A61B1/07 , G02B23/2415 , G02B23/2469
摘要： A flexible high resolution endoscope is provided herein. The endoscope comprises: a plurality of optical fiber bundles; a plurality of lenses in a one-to-one relationship with the plurality of optical fiber bundles; and, a plurality of cameras in a one-to-one relationship with the plurality of optical fiber bundles, each respective optical fiber bundle, of the plurality of optical fiber bundles, having a respective lens, of the plurality of lenses, located at a respective distal end, and a camera, of the plurality of cameras, located at a respective proximal end, the plurality of optical fiber bundles being coupled together at a common distal end, and otherwise being uncoupled from one another, a bending radius of the endoscope defined by a largest respective bending radius of each of the plurality of optical fiber bundles.
摘要翻译：这里提供了一种灵活的高分辨率内窥镜。该内窥镜包括：多个光纤束; 与所述多个光纤束呈一对一关系的多个透镜; 以及与所述多个光纤束中的多个光纤束各自的光纤束成一对一关系的多个照相机，所述多个光纤束中的所述多个光纤束具有多个透镜中的相应透镜，所述多个照相机中的相应的远端和照相机位于相应的近端处，所述多个光纤束在共同的远端处联接在一起，否则彼此脱开，所述内窥镜的弯曲半径由多个光纤束中的每一个的最大相应弯曲半径限定。

5. 发明申请

WO2018032083A1 METHODS AND SYSTEMS FOR REGISTRATION OF VIRTUAL SPACE WITH REAL SPACE IN AN AUGMENTED REALITY SYSTEM 审中-公开
标题翻译：在增强现实系统中用真实空间注册虚拟空间的方法和系统
公开(公告)号：WO2018032083A1
公开(公告)日：2018-02-22
申请号：PCT/CA2016/050961
申请日：2016-08-17
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , THOMAS, Monroe Milas
发明人： THOMAS, Monroe Milas
IPC分类号： A61B34/20 , A61B34/10 , G06F19/00
CPC分类号： A61B34/20 , A61B34/10 , A61B34/30 , A61B90/36 , A61B90/361 , A61B90/39 , A61B2034/2048 , A61B2034/2055 , A61B2034/2065 , A61B2090/365 , A61B2090/3975 , A61B2090/502 , G06F3/017 , G06T7/50 , G06T7/70 , G06T19/006 , G06T19/20 , G16H20/40
摘要： A method and system to use an augmented reality device in a surgical procedure. The method includes rendering, on the display of the device, a model of a patient reference object; in response to receiving input, moving the model of the patient reference object in an augmented reality coordinate system; determining that the model is aligned with the patient reference object in real world space when viewed through the display and, based on that determination, identifying a first transform from the augmented reality coordinate system to a navigation coordinate system used by an optical navigation system for tracking the patient reference object; subsequently transferring patient image data from the navigation coordinate system to the augmented reality coordinate system using an inverse of the first transform; and displaying the patient image data on the display to augment a real world view of a patient.
摘要翻译：在外科手术中使用增强现实设备的方法和系统。该方法包括在装置的显示器上呈现患者参考对象的模型; 响应于接收到输入，在增强现实坐标系中移动患者参考对象的模型; 当通过显示器观看时，确定模型与真实世界空间中的患者参考对象对齐，并且基于该确定，识别从增强现实坐标系到用于跟踪的光学导航系统所使用的导航坐标系的第一变换患者参考对象; 随后使用第一变换的逆来将患者图像数据从导航坐标系转移到增强现实坐标系; 并在显示器上显示患者图像数据以增加患者的真实世界视图。

6. 发明申请

WO2018014140A1 METHOD FOR MULTIMODAL TISSUE IMAGING BASED ON RESONANCE RAMAN EFFECT ON METAL BASED MRI CONTRAST AGENTS AND METHOD FOR IONIZING LASER PLUMES THROUGH ATMOSPHERIC PRESSURE CHEMICAL IONIZATION 审中-公开
标题翻译：基于共振拉曼效应的基于金属的MRI造影剂的多组织成像方法以及通过大气压力离子化激光的方法化学电离
公开(公告)号：WO2018014140A1
公开(公告)日：2018-01-25
申请号：PCT/CA2017/050887
申请日：2017-07-24
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , FRANJIC, Kresimir
发明人： FRANJIC, Kresimir
IPC分类号： G01R33/58 , A61B5/055 , A61K49/10 , C07C229/76 , C07D257/00 , H01J49/16
摘要： Disclosed herein is a method for multimodal imaging during a medical procedure using magnetic resonance imaging (MRI) and Raman optical imaging which involves administering an MRI imaging contrast agent that a chemical structure having charge-transfer electronic transitions. The tissue is imaged using and MRI device and the tissue is illuminated with excitation light that has spectral components that are approximately tuned close to one of the charge-transfer electronic transitions thereby producing enhanced Raman optical signals which are analyzed to produce Raman imaging data followed by registering the MRI and Raman imaging data. The present disclosure also provides a method for ionizing laser plumes through atmospheric pressure chemical ionization.
摘要翻译：本文公开了一种用于在使用磁共振成像（MRI）和拉曼光学成像的医学程序期间的多模式成像的方法，其涉及施用具有电荷转移电子跃迁的化学结构的MRI成像造影剂。使用MRI装置对组织进行成像，并且用具有近似调谐到靠近电荷转移电子跃迁之一的光谱分量的激发光照射组织，从而产生增强的拉曼光学信号，其被分析以产生拉曼成像数据，然后是记录MRI和拉曼成像数据。本公开还提供了一种通过大气压化学电离来电离激光羽流的方法。

7. 发明申请

WO2017185161A1 MULTI-MODAL OPTICAL IMAGING SYSTEM FOR TISSUE ANALYSIS 审中-公开
标题翻译：用于组织分析的多模式光学成像系统
公开(公告)号：WO2017185161A1
公开(公告)日：2017-11-02
申请号：PCT/CA2016/050502
申请日：2016-04-29
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , FRANJIC, Kresimir , MAK, Siu Wai Jacky , HYNNA, Kai Michael , WOOD, Michael Frank Gunter , KUCHNIO, Piotr , BISMILLA, Yusuf , HOLMES, Lachlan Noel , BRIGHT, Stewart , CHEUNG, Aaron Yu Lai , KUZYK, Yuri Alexander , TAUB, Aryeh Benjamin , REZAEI, Sanaz
发明人： FRANJIC, Kresimir , MAK, Siu Wai Jacky , HYNNA, Kai Michael , WOOD, Michael Frank Gunter , KUCHNIO, Piotr , BISMILLA, Yusuf , HOLMES, Lachlan Noel , BRIGHT, Stewart , CHEUNG, Aaron Yu Lai , KUZYK, Yuri Alexander , TAUB, Aryeh Benjamin , REZAEI, Sanaz
IPC分类号： G01N35/00 , G01B11/24 , G01B21/20 , G01N21/84 , G01N33/02 , G01N33/483
CPC分类号： G01N21/65 , G01B9/02091 , G01B11/24 , G01N21/31 , G01N21/35 , G01N21/474 , G01N21/4795 , G01N21/636 , G01N21/6408 , G01N21/6456 , G01N21/6486 , G01N2021/653 , G01N2021/655
摘要： A modular system for organic sample analysis is disclosed which includes a sample stage including a support platform and a motorized positioning mechanism mounted on the support platform, and a sample holder mounted on the motorized positioning mechanism upon which a sample is placed. A probe support rack is mounted on the support platform and two or more bio-imaging probes mounted on the probe support and arranged in a pre- defined geometry with respect to each other, and at least one bio-imaging probe havs a field of view independent of all other bio-imaging probes. The system includes a computer controller connected to the motorized positioning mechanism and the two or more bio-imaging probes. The computer is programmed for controlling motorized positioning mechanism to move the sample holder having the sample located thereon to positions in the field of view of each bio-imaging probe where the sample can be analyzed individually by each of the bio-imaging probes. The computer includes a storage medium for storing an imaging data from each bio-imaging probe. The computer is programmed for spatially correlating imaging data of the selected volume of interest with the imaging data obtained from at least one other bio-imaging probe and storing the spatially correlated imaging data in the computer storage medium.
摘要翻译：公开了一种用于有机样品分析的模块化系统，其包括样品台和样品架，样品台包括支撑平台和安装在支撑平台上的机动定位机构，样品架安装在机动定位机构上，样品被放置。探针支撑架安装在支撑平台上并且两个或更多个生物成像探针安装在探针支撑件上并且相对于彼此以预定几何形状布置，并且至少一个生物成像探针具有视场独立于所有其他生物成像探针。该系统包括连接到机动定位机构和两个或更多个生物成像探针的计算机控制器。计算机被编程为用于控制机动定位机构以将其上具有样品的样品保持器移动到每个生物成像探头的视场中的位置，其中样品可由每个生物成像探头单独分析。该计算机包括用于存储来自每个生物成像探头的成像数据的存储介质。计算机被编程用于将所选感兴趣体积的成像数据与从至少一个其他生物成像探针获得的成像数据在空间上相关联，并将空间相关成像数据存储在计算机存储介质中。

8. 发明申请

WO2017173518A1 MULTI-METRIC SURGERY SIMULATOR AND METHODS 审中-公开
标题翻译：多米制外科模拟器和方法
公开(公告)号：WO2017173518A1
公开(公告)日：2017-10-12
申请号：PCT/CA2016/050389
申请日：2016-04-05
申请人： GMEINER, Timotheus Anton , KERINS, Fergal , CHEUNG, Aaron Yu Lai , HOANG, Kimberly Bojanowski , SYNAPTIVE MEDICAL (BARBADOS) INC.
发明人： GMEINER, Timotheus Anton , KERINS, Fergal , CHEUNG, Aaron Yu Lai , HOANG, Kimberly Bojanowski
IPC分类号： G09B9/00 , G09B23/28 , G09B23/30
摘要： Multi-metric surgery simulator devices, systems, and methods, involving at least one sensor configured to collect surgical training performance data relevant to at least one surgical task, the at least one sensor configured to operate with a surgical navigation system comprising a processor, the processor configurable, by way of a set of executable instructions storable in relation to a non-transitory medium, to perform at least one of analyze collected data, transform the collected data, and provide feedback in relation thereto; and at least one surgery simulator apparatus operatively coupled with the at least one sensor, the at least one surgery simulator apparatus configured to operate with a tracking system, whereby collected data is obtainable and clinical performance in relation to the at least one surgical task is quantitatively evaluable and progressively improvable.
摘要翻译：涉及至少一个传感器的多度量外科手术模拟器装置，系统和方法，所述至少一个传感器被配置为收集与至少一个手术任务相关的手术训练性能数据，所述至少一个传感器被配置为利用包括处理器的外科手术导航系统，所述处理器通过一组可执行指令可相对于非临时性介质配置，以执行分析收集的数据，变换所收集的数据和提供与其有关的反馈中的至少一个 ; 以及与所述至少一个传感器可操作地耦合的至少一个手术模拟器装置，所述至少一个手术模拟器装置被配置为与跟踪系统一起操作，由此可以获得收集的数据并且定量地与所述至少一个手术任务相关的临床表现可评估和逐步改进。

9. 发明申请

WO2017143427A1 SYSTEM AND METHOD FOR SCOPE BASED DEPTH MAP ACQUISITION 审中-公开
标题翻译：用于基于范围的深度图获取的系统和方法
公开(公告)号：WO2017143427A1
公开(公告)日：2017-08-31
申请号：PCT/CA2016/050189
申请日：2016-02-25
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , ABHARI, Kamyar , SELA, Gal , WOOD, Michael Frank Gunter , HYNNA,, Kai Michael , LEE, Tammy Kee-wai
发明人： ABHARI, Kamyar , SELA, Gal , WOOD, Michael Frank Gunter , HYNNA,, Kai Michael , LEE, Tammy Kee-wai
IPC分类号： A61B34/20 , A61B1/04 , A61B34/00 , A61B90/30
CPC分类号： A61B34/20 , A61B1/00009 , A61B17/3423 , A61B34/00 , A61B34/10 , A61B90/30 , A61B90/37 , A61B2034/107 , A61B2034/2057 , A61B2034/2065 , A61B2090/365 , A61B2090/366 , G06T7/521 , G06T2207/10016 , G06T2207/10021 , G06T2207/10028 , G06T2207/10048 , G06T2207/10068 , G06T2207/30016 , G06T2207/30204 , H04N5/272 , H04N13/271
摘要： A medical navigation system is provided for acquiring a depth map of a surgical site of interest in a patient. The medical navigation system comprises a camera, a light projecting device, a display, and a controller. The controller has a processor coupled to a memory. The controller is configured to generate a signal provided to the light projecting device to project an edge indicator on the surgical site of interest, generate a signal to operate the camera to perform a focus sweep and capture a plurality of images during the focus sweep where the plurality of images includes the projected edge indicator, receive from the camera data representing the plurality of images captured during the focus sweep, and generate a depth map of the surgical site of interest using the data representing the plurality of images.
摘要翻译：医疗导航系统被提供用于获取患者中感兴趣的手术部位的深度图。医疗导航系统包括照相机，投光装置，显示器和控制器。控制器具有耦合到存储器的处理器。控制器被配置为生成提供给光投射设备的信号以在感兴趣的手术部位上投影边缘指示符，生成信号以操作相机执行聚焦扫掠并且在聚焦扫掠期间捕获多个图像，其中多个图像包括投影边缘指示符，从相机接收表示聚焦扫描期间捕获的多个图像的数据，并且使用表示多个图像的数据生成感兴趣的手术部位的深度图。

10. 发明申请

WO2017134536A1 SYSTEM AND METHOD FOR PROVIDING SURGICAL GUIDANCE BASED ON POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY 审中-公开
标题翻译：基于极化敏感的光学相干层析成像提供手术指导的系统和方法
公开(公告)号：WO2017134536A1
公开(公告)日：2017-08-10
申请号：PCT/IB2017/050226
申请日：2017-01-16
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC. , MAK, Siu Wai Jacky
发明人： MAK, Siu Wai Jacky
IPC分类号： A61B34/10 , A61B34/00 , A61B5/00
CPC分类号： A61B5/0066 , A61B5/00 , A61B5/0035 , A61B5/0084 , A61B17/3421 , A61B34/00 , A61B34/10 , A61B90/37 , A61B2034/107 , A61B2034/2055 , A61B2090/365 , A61B2090/3735 , G01B9/02091 , G01N21/4795
摘要： Systems and methods are provided for identifying a suitable surgical location and/or trajectory for proceeding with a surgical procedure based on local polarization-sensitive optical coherence tomography imaging (PSOCT). PSOCT images are obtained of a tissue region and are processed to provide a spatial map of anisotropic structure within the tissue region. The anisotropic structure is processed to determine one or more suitable surgical locations and/or trajectories for avoiding or reducing damage to local anisotropic tissue structure identified within the tissue region. The spatial map of the anisotropic structure is registered with pre-operative volumetric image data identifying anisotropic tissue structure within a second tissue region that is larger than the tissue region imaged by PSOCT.
摘要翻译：提供了系统和方法，用于基于局部偏振敏感光学相干断层扫描成像（PSOCT）来识别用于继续进行外科手术的合适手术位置和/或轨迹。获得组织区域的PSOCT图像并进行处理以提供组织区域内的各向异性结构的空间图。处理各向异性结构以确定用于避免或减少对在组织区域内识别的局部各向异性组织结构的损伤的一个或多个合适手术位置和/或轨迹。各向异性结构的空间图与手术前体积图像数据配准，所述手术体积图像数据识别比PSOCT成像的组织区域大的第二组织区域内的各向异性组织结构。

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