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1. 发明申请

WO2007143304A2 MEDICAL ELECTRICAL LEAD WITH DEPLOYABLE FIXATION FEATURES 审中-公开
标题翻译：具有可配置固定功能的医用电气引线
公开(公告)号：WO2007143304A2
公开(公告)日：2007-12-13
申请号：PCT/US2007/067885
申请日：2007-05-01
申请人： CARDIAC PACEMAKERS, INC. , SOLTIS, Brian D. , TOCKMAN, Bruce A. , STALKER, Kent C.B. , JOHNSON, Eric T. , D'AQUANNI, Peter J.
发明人： SOLTIS, Brian D. , TOCKMAN, Bruce A. , STALKER, Kent C.B. , JOHNSON, Eric T. , D'AQUANNI, Peter J.
IPC分类号： A61N1/00 , A61N1/05
CPC分类号： A61N1/0573 , A61B18/1492 , A61N1/056 , A61N2001/0585
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. The fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。固定特征包括引线的可偏转区域，其在展开构型中使得引线主体的表面接合心脏血管的内表面。

2. 发明申请

WO2012030871A1 EXPANDABLE DEVICES 审中-公开
标题翻译：可扩展的设备
公开(公告)号：WO2012030871A1
公开(公告)日：2012-03-08
申请号：PCT/US2011/049804
申请日：2011-08-30
申请人： CELONOVA BIOSCIENCES, INC. , DENISON, Andy, Edward , STALKER, Kent, C.b. , BATES, Mark
发明人： DENISON, Andy, Edward , STALKER, Kent, C.b. , BATES, Mark
IPC分类号： A61F2/90
CPC分类号： A61F2/89 , A61F2/04 , A61F2/82 , A61F2/915 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2230/0054 , A61F2230/0069
摘要： An expandable, bistable open cell design incorporates the following features: a first relatively stiff portion (152) having first and second ends and a first relatively flexible portion (154) connected to the first and second ends of the first relatively stiff portion, the first relatively stiff portion and the first relatively flexible portion substantially surrounding a first open area (156) of the stent structure; a second relatively stiff portion (158) having first and second ends and a second relatively flexible portion (160) connected to the first and second ends of the first relatively stiff portion, the first relatively stiff portion and the first relatively flexible portion substantially surrounding a second open area (162) of the stent structure; and an opening (1 10) formed through the first relatively stiff portion and the second relatively flexible portion such that the opening connects the first and second open areas, thereby creating first and second intermediate ends (152a, 152b) of the first relatively stiff portion and first and second intermediate ends (160a, 160b) of the second relatively flexible portion. The first intermediate end (152a) of the relatively stiff portion is connected to the first intermediate end (160a) of the relatively flexible portion so as to create a first inward apex (170), the second intermediate end (152b) of the relatively stiff portion is connected to the second intermediate end (160b) of the relatively flexible portion so as to create a second inward apex (172), and the stent structure is configured such that, in a collapsed configuration, the first inward apex (170) is in contact with the second inward apex (172) and, in an expanded configuration, the first inward apex is biased to move in a first circumferential direction and the second inward apex is biased to move in a second circumferential direction that is different than the first circumferential direction.
摘要翻译：可膨胀的双稳态开孔结构具有以下特征：具有第一和第二端的第一相对较硬的部分（152）和连接到第一相对刚性部分的第一和第二端的第一相对柔性部分（154），第一相对硬的部分和第一相对柔性部分基本上围绕支架结构的第一开口区域（156）; 具有第一和第二端部的第二相对刚性部分（158）和连接到第一相对刚性部分的第一和第二端部的第二相对柔性部分（160），第一相对刚性部分和第一相对柔性部分基本上围绕第二开放区域（162）; 以及通过所述第一相对刚性部分形成的开口（110）和所述第二相对柔性部分，使得所述开口连接所述第一和第二开口区域，从而形成所述第一相对刚性部分的第一和第二中间端（152a，152b）以及第二相对柔性部分的第一和第二中间端（160a，160b）。相对刚性部分的第一中间端（152a）连接到相对柔性部分的第一中间端（160a），以便产生第一内向顶点（170），第二中间端（152b）具有较硬的部分连接到相对柔性部分的第二中间端（160b），以便形成第二内向顶点（172），并且支架结构构造成使得在折叠构型中，第一向内顶点（170）是与第二内向顶点（172）接触，并且在膨胀构造中，第一向内顶点被偏压以在第一圆周方向上移动，并且第二内向顶点被偏压以在不同于第一内顶端的第二圆周方向上移动圆周方向。

3. 发明申请

WO2010042882A3 INVENTORY SPARING CATHETER SYSTEM 审中-公开
公开(公告)号：WO2010042882A3
公开(公告)日：2010-04-15
申请号：PCT/US2009/060259
申请日：2009-10-09
申请人： NEXEON MEDSYSTEMS, INC. , STALKER, Kent, C.B. , WHITFIELD, John, D. , BATES, Mark, C. , D'AQUANNI, Peter, J. , HABEGER, Jason, Andrew
发明人： STALKER, Kent, C.B. , WHITFIELD, John, D. , BATES, Mark, C. , D'AQUANNI, Peter, J. , HABEGER, Jason, Andrew
IPC分类号： A61M25/01 , A61M25/10 , A61M29/02 , A61F2/84 , A61M25/00
摘要： The application relates to a catheter system (200) having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through, at least a portion of the catheter body (208). A first opening (206) can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath (204) can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position.

4. 发明申请

WO2007143306A1 CARDIAC LEAD HAVING STIFFENING STRUCTURES FOR FIXATION 审中-公开
标题翻译：具有固定结构的CARDIAC引线
公开(公告)号：WO2007143306A1
公开(公告)日：2007-12-13
申请号：PCT/US2007/067887
申请日：2007-05-01
申请人： CARDIAC PACEMAKERS, INC. , TOCKMAN, Bruce A. , SOLTIS, Brian D. , JOHNSON, Eric T. , STALKER, Kent C.B. , D'AQUANNI, Peter J. , ZAREMBO, Paul E.
发明人： TOCKMAN, Bruce A. , SOLTIS, Brian D. , JOHNSON, Eric T. , STALKER, Kent C.B. , D'AQUANNI, Peter J. , ZAREMBO, Paul E.
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. The stiffening structures include one or more inflatable chambers integrally formed in the lead body.
摘要翻译：适于至少部分地固定在心脏血管内的心脏引线。在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。远端区域被构造成使得电极和远端尖端可以植入心脏血管。铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。加强结构包括一体形成在引线体内的一个或多个可充气室。

5. 发明申请

WO2008088967A1 LEAD WITH INFLATABLE FIXATION MECHANISM 审中-公开
标题翻译：具有可充气的固定机构
公开(公告)号：WO2008088967A1
公开(公告)日：2008-07-24
申请号：PCT/US2008/050455
申请日：2008-01-08
申请人： CARDIAC PACEMAKERS, INC. , JOHNSON, Eric, T. , SOLTIS, Brian, D. , TOCKMAN, Bruce, A. , D'AQUANNI, Peter, J. , STALKER, Kent, C.B. , SMITH, Gayla, A.
发明人： JOHNSON, Eric, T. , SOLTIS, Brian, D. , TOCKMAN, Bruce, A. , D'AQUANNI, Peter, J. , STALKER, Kent, C.B. , SMITH, Gayla, A.
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61M25/04 , A61M25/10 , A61N2001/0585
摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.
摘要翻译：构造成用于刺激心脏左侧（即，左心室）的医用电引线。在一个实施例中，引线包括包括内表面的细长引线主体。可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面，用于固定远端的铅。引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

6. 发明申请

WO2007143303A2 MEDICAL ELECTRICAL LEAD WITH EXPANDABLE FIXATION FEATURES 审中-公开
标题翻译：具有可扩充固定功能的医用电气引线
公开(公告)号：WO2007143303A2
公开(公告)日：2007-12-13
申请号：PCT/US2007/067884
申请日：2007-05-01
申请人： CARDIAC PACEMAKERS, INC. , SOLTIS, Brian D. , TOCKMAN, Bruce A. , STALKER, Kent C.b. , JOHNSON, Eric T. , D'AQUANNI, Peter J.
发明人： SOLTIS, Brian D. , TOCKMAN, Bruce A. , STALKER, Kent C.b. , JOHNSON, Eric T. , D'AQUANNI, Peter J.
IPC分类号： A61N1/00 , A61N1/05
CPC分类号： A61N1/057 , A61B18/1492 , A61B2017/00243
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. The fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。固定特征包括用于在展开构型中与容器的内表面接合的可径向扩张的结构。

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