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    • 3. 发明申请
    • ABSORBABLE SYNTHETIC BRAIDED MATRIX FOR BREAST RECONSTRUCTION AND HERNIA REPAIR
    • 用于乳腺重建和HERNIA修复的可吸收合成基质
    • WO2014164769A1
    • 2014-10-09
    • PCT/US2014/023424
    • 2014-03-11
    • SOFT TISSUE REGENERATION, INC.
    • REILLY, Joseph, W.LAURENCIN, Cato, T.
    • A61F2/00A61F2/12D04B21/00D04B1/00
    • A61F2/0063A61F2/12A61F2002/0068D04C1/06D10B2509/08
    • A braided, rather than woven, three-dimensional matrix has been developed to provide mechanical support in breast reconstruction or a mastopexy procedure. The braided three-dimensional matrix may be used to assist in hernia repair procedures. The matrix is a supple, strong, and flexible material, that can increase 50% to 100% in size when stretched along the vertical plane, but only extends by about 10% to 20% in length when stretched along the horizontal plane. Although the matrix is degradable, it provides sufficient mechanical and structural support for six to twelve months following implantation to allow for repair or growth of the breast tissue or the abdominal wall. The matrix is formed of three-dimensional braided multifilament polymeric fibers plied to create yarn bundles, and wherein the matrix comprises an inter-connected, open pore structure that enables even and random distribution and in-growth of cells.
    • 已经开发了编织而不是织造的三维矩阵,以在乳房重建或乳房解剖过程中提供机械支撑。 编织三维矩阵可用于辅助疝修补程序。 该基质是柔软,坚固且柔软的材料,当沿着垂直平面拉伸时,可以增加50%至100%的尺寸,但是当沿着水平面拉伸时,其仅延伸约10%至20%的长度。 尽管基质是可降解的,但它在植入后六至十二个月可提供足够的机械和结构支持,以允许乳房组织或腹壁的修复或生长。 基质由三维编织的复丝聚合物纤维形成,以生成纱线束,并且其中基质包括互连的开孔结构,其能够均匀和随机分布和生长细胞。