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1. 发明申请

WO2010088517A8 METHODS AND SYSTEMS FOR PURIFYING TRANSFERRING AND/OR MANIPULATING NUCLEIC ACIDS 审中-公开
标题翻译：用于净化转运和/或操作核酸的方法和系统
公开(公告)号：WO2010088517A8
公开(公告)日：2011-07-28
申请号：PCT/US2010022586
申请日：2010-01-29
申请人： US HEALTH , UNIV MARYLAND , EMMERT-BUCK MICHAEL R , ARMANI MICHAEL , SMELA ELISABETH , SHAPIRO BENJAMIN , TANGREA MICHAEL A , RODRIGUEZ-CANALES JAIME , CHUAQUI RODRIGO , GILLESPIE JOHN
发明人： EMMERT-BUCK MICHAEL R , ARMANI MICHAEL , SMELA ELISABETH , SHAPIRO BENJAMIN , TANGREA MICHAEL A , RODRIGUEZ-CANALES JAIME , CHUAQUI RODRIGO , GILLESPIE JOHN
IPC分类号： C12P19/34
CPC分类号： C12Q1/6806 , B01L3/5025 , B01L3/50853 , B01L3/50857 , B01L7/52 , B01L2300/0819 , B01L2400/0415 , B01L2400/0487 , C12N15/1006 , C12Q2565/631 , C12Q2565/513 , C12Q2547/101 , C12Q2523/125
摘要： The disclosure provides methods, systems, and devices for purifying, transferring or manipulating nucleic acids while maintaining the 2D spatial relationship of the nucleic acids as they were present in the original sample having 2D spatial information.
摘要翻译：本公开提供用于纯化，转移或操纵核酸的方法，系统和装置，同时保持核酸的2D空间关系，因为它们存在于具有2D空间信息的原始样品中。

2. 发明申请

WO2010088517A1 METHODS AND SYSTEMS FOR PURIFYING TRANSFERRING AND/OR MANIPULATING NUCLEIC ACIDS 审中-公开
标题翻译：用于净化转运和/或操作核酸的方法和系统
公开(公告)号：WO2010088517A1
公开(公告)日：2010-08-05
申请号：PCT/US2010/022586
申请日：2010-01-29
申请人： THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES , UNIVERSITY OF MARYLAND, COLLEGE PARK , EMMERT-BUCK, Michael, R. , ARMANI, Michael , SMELA, Elisabeth , SHAPIRO, Benjamin , TANGREA, Michael, A. , RODRIGUEZ-CANALES, Jaime , CHUAQUI, Rodrigo , GILLESPIE, John
发明人： EMMERT-BUCK, Michael, R. , ARMANI, Michael , SMELA, Elisabeth , SHAPIRO, Benjamin , TANGREA, Michael, A. , RODRIGUEZ-CANALES, Jaime , CHUAQUI, Rodrigo , GILLESPIE, John
IPC分类号： C12P19/34
CPC分类号： C12Q1/6806 , B01L3/5025 , B01L3/50853 , B01L3/50857 , B01L7/52 , B01L2300/0819 , B01L2400/0415 , B01L2400/0487 , C12N15/1006 , C12Q2565/631 , C12Q2565/513 , C12Q2547/101 , C12Q2523/125
摘要： The disclosure provides methods, systems, and devices for purifying, transferring or manipulating nucleic acids while maintaining the 2D spatial relationship of the nucleic acids as they were present in the original sample having 2D spatial information.
摘要翻译：本公开提供用于纯化，转移或操纵核酸的方法，系统和装置，同时保持核酸的2D空间关系，因为它们存在于具有2D空间信息的原始样品中。

3. 发明申请

WO1996034417A1 A MICROMACHINED STRUCTURE AND USE THEREOF, AND A MICROMACHINED DEVICE AND A METHOD FOR THE MANUFACTURE THEREOF 审中-公开
标题翻译： MICROMACHINED结构及其用途以及微型设备及其制造方法
公开(公告)号：WO1996034417A1
公开(公告)日：1996-10-31
申请号：PCT/SE1996000539
申请日：1996-04-24
申请人： SMELA, Elisabeth , IGANÄS, Olle , LUNDSTRÖM, Ingemar
IPC分类号： H01L29/00
CPC分类号： H01H1/0036
摘要： A micromachined structure which comprises one or more bi- or multi-layer hinges and one or more rigid components, the hinges serving to move and/or position the rigid component(s) by bending under the influence of one or more stimulus/stimuli. In a preferred embodiment, the hinges are flexible, offering a large degree of bending, and are small in size compared with the area of the rigid components. In a further preferred embodiment, the hinges are used to fold together the rigid components into predetemined three-dimensional structures and/or to achieve three-dimensional positioning of one or more rigid components. In a further preferred embodiment, the bending of the hinges can be continuously controlled between the minimum and maximum degree of bending. In a further preferred embodiment, the hinges comprise an organic layer such as a conducting polymer.
摘要翻译：一种微加工结构，其包括一个或多个双层或多层铰链和一个或多个刚性部件，铰链用于通过在一个或多个刺激/刺激的影响下弯曲来移动和/或定位刚性部件。在优选实施例中，铰链是柔性的，提供大的弯曲度，并且与刚性部件的面积相比尺寸小。在另一优选实施例中，铰链用于将刚性部件折叠成预先设计的三维结构和/或实现一个或多个刚性部件的三维定位。在另一优选实施例中，可以在最小和最大弯曲度之间连续地控制铰链的弯曲。在另一优选实施例中，铰链包括有机层，例如导电聚合物。

4. 发明申请

WO1996028841A1 A METHOD FOR THE MANUFACTURING OF MICROMACHINED STRUCTURES AND A MICROMACHINED STRUCTURE MANUFACTURED USING SUCH METHOD 审中-公开
标题翻译：制造微结构结构的方法和使用这种方法制造的微结构结构
公开(公告)号：WO1996028841A1
公开(公告)日：1996-09-19
申请号：PCT/SE1996000308
申请日：1996-03-08
申请人： SMELA, Elisabeth , INGANÄS, Olle , LUNDSTRÖM, Ingemar , ÖHMAN, Ove
IPC分类号： H01L21/00
CPC分类号： B81C1/00952 , Y10T428/12396 , Y10T428/12472 , Y10T428/12486 , Y10T428/12528 , Y10T428/12549 , Y10T428/12569 , Y10T428/12674 , Y10T428/12806 , Y10T428/12875
摘要： The invention relates to a method for manufacturing a micromachined structure to be at least partly released from a substrate surface. A surface contact area, over which structure and the said substrate surface are in surface contact with each other during the manufacturing step, is divided into at least a first and a second contact zone, the adhesiveness between the structure and the substrate being greater in the first contact zone than in the second contact zone. As a manufacturing step, or as a step subsequent to the manufacturing, the structure can be released from the substrate surface at least over said second contact zone. The completed structure may also by completely loose from the substrate. The invention is also directed to a micromachined structure manufactured according to the method.
摘要翻译：本发明涉及一种用于制造至少部分地从衬底表面释放的微加工结构的方法。在制造步骤期间，在其上结构和所述基板表面彼此表面接触的表面接触区域被分成至少第一和第二接触区域，结构和基板之间的粘合性在第一接触区比在第二接触区中。作为制造步骤，或作为制造之后的步骤，该结构可以至少在所述第二接触区域上从衬底表面释放。完成的结构也可以从基底完全松散。本发明还涉及根据该方法制造的微加工结构。

5. 发明申请

WO2006133440A3 ELECTRICALLY CONDUCTIVE METAL IMPREGNATED ELASTOMER MATERIALS AND METHODS OF FORMING ELECTRICALLY CONDUCTIVE METAL IMPREGNATED ELASTOMER MATERIALS 审中-公开
公开(公告)号：WO2006133440A3
公开(公告)日：2006-12-14
申请号：PCT/US2006/022672
申请日：2006-06-09
申请人： UNIVERSITY OF MARYLAND , SMELA, Elisabeth , DELILLE, Remi , URDANETA, Mario , MOSELEY, Samuel
发明人： SMELA, Elisabeth , DELILLE, Remi , URDANETA, Mario , MOSELEY, Samuel
IPC分类号： C08K3/10 , C08C19/26 , C08J3/205 , C08L43/00
摘要： An electrically conductive, compliant elastomer material that is impregnated with a metal is formed by combining a metal salt with an elastomer precursor material to form a metal salt/precursor mixture, curing the metal salt/precursor mixture to form an elastomer impregnated with metal salt, and treating the elastomer impregnated with metal salt with a chemical reducing composition so as to convert at least a portion of the metal salt impregnated within the elastomer to a metal. The elastomer can be subjected to a suitable solvent that swells the elastomer during the chemical reduction of the metal salt to metal, which enhances the mechanical and electrical properties of the resultant metal impregnated elastomer material.

6. 发明申请

WO2006133440A2 ELECTRICALLY CONDUCTIVE METAL IMPREGNATED ELASTOMER MATERIALS AND METHODS OF FORMING ELECTRICALLY CONDUCTIVE METAL IMPREGNATED ELASTOMER MATERIALS 审中-公开
标题翻译：导电金属导电弹性体材料及形成电导金属侵蚀弹性体材料的方法
公开(公告)号：WO2006133440A2
公开(公告)日：2006-12-14
申请号：PCT/US2006022672
申请日：2006-06-09
申请人： UNIV MARYLAND , SMELA ELISABETH , DELILLE REMI , URDANETA MARIO , MOSELEY SAMUEL
发明人： SMELA ELISABETH , DELILLE REMI , URDANETA MARIO , MOSELEY SAMUEL
IPC分类号： C08K3/08
CPC分类号： C08K3/08
摘要： An electrically conductive, compliant elastomer material that is impregnated with a metal is formed by combining a metal salt with an elastomer precursor material to form a metal salt/precursor mixture, curing the metal salt/precursor mixture to form an elastomer impregnated with metal salt, and treating the elastomer impregnated with metal salt with a chemical reducing composition so as to convert at least a portion of the metal salt impregnated within the elastomer to a metal. The elastomer can be subjected to a suitable solvent that swells the elastomer during the chemical reduction of the metal salt to metal, which enhances the mechanical and electrical properties of the resultant metal impregnated elastomer material.
摘要翻译：通过将金属盐与弹性体前体材料组合以形成金属盐/前体混合物，固化金属盐/前体混合物以形成浸渍有金属盐的弹性体，形成浸渍有金属的导电的柔性弹性体材料，并用化学还原组合物处理浸渍有金属盐的弹性体，以将至少一部分浸渍在弹性体内的金属盐转化为金属。在将金属盐化学还原成金属的过程中，弹性体可以经受合适的溶剂，从而使弹性体膨胀，这增强了所得金属浸渍的弹性体材料的机械和电学性质。

7. 发明申请

WO2005092605A1 STRUCTURES AND METHODS FOR INCREASING THE SPEED OF ELECTROACTIVE POLYMERS 审中-公开
标题翻译：增加电极聚合物速度的结构和方法
公开(公告)号：WO2005092605A1
公开(公告)日：2005-10-06
申请号：PCT/US2005/006776
申请日：2005-03-03
申请人： UNIVERSITY OF MARYLAND , SMELA, Elisabeth , WANG, Xuezheng
发明人： SMELA, Elisabeth , WANG, Xuezheng
IPC分类号： B32B3/26
CPC分类号： F03G7/005 , B82Y30/00 , H01B1/122 , H01M4/045 , H01M4/0497 , H01M4/137 , H01M4/364 , H01M4/602 , H01M8/0289 , H01M8/10 , H01M2300/0082 , Y10T428/24273 , Y10T428/249978 , Y10T428/249979
摘要： Structures are provided that include electroactive polymers. According to these structures, the electroactive materials have enhanced conductivity in a first direction. Also, the structures include either pores or inclusions. These pores or inclusions are non-parallel to the first direction. In addition, methods for forming structures that include electroactive polymers that have enhanced conductivity in a first direction are provided. These methods allow for pores and/or inclusions to be formed in the electroactive polymers.
摘要翻译：提供包括电活性聚合物的结构。根据这些结构，电活性材料在第一方向上具有增强的导电性。此外，结构包括孔或夹杂物。这些孔或夹杂物不平行于第一方向。此外，提供了形成包括在第一方向上具有增强的导电性的电活性聚合物的结构的方法。这些方法允许在电活性聚合物中形成孔和/或夹杂物。

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