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1. 发明申请

WO2008037740A2 BEVERAGE SUITABLE TO RETARD THE CELLULAR DEGENERATION WHICH ACCOMPANIES AGEING 审中-公开
标题翻译：饮料适合延缓衰老的细胞衰老
公开(公告)号：WO2008037740A2
公开(公告)日：2008-04-03
申请号：PCT/EP2007/060216
申请日：2007-09-26
申请人： GENALTA S.R.L. , BERNASCONI, Sara , BERTINI, Ivano , LUCCIOLA, Isidoro , LUCHINAT, Claudio , QUATTRONE, Alessandro , SCAPAGNINI, Giovanni
发明人： BERNASCONI, Sara , BERTINI, Ivano , LUCCIOLA, Isidoro , LUCHINAT, Claudio , QUATTRONE, Alessandro , SCAPAGNINI, Giovanni
IPC分类号： A23L1/30 , A23L1/305 , A23L2/52
CPC分类号： A23L2/52 , A23L33/105 , A23L33/18 , A23V2002/00 , A23V2250/1642 , A23V2250/161 , A23V2250/032 , A23V2200/322 , A23V2200/302 , A23V2250/2116 , A23V2250/7056 , A23V2250/72
摘要： The object of the present invention is a beverage suitable to retard the cellular degeneration which accompanies ageing, comprising epigallocatechin gallate and L-carnosine, possibly associated with other active components.
摘要翻译：本发明的目的是适于延缓伴随老化的细胞变性的饮料，其包含可能与其它活性组分相关的表没食子儿茶素没食子酸酯和L-肌肽。

2. 发明申请

WO2008037740A3 BEVERAGE SUITABLE TO RETARD THE CELLULAR DEGENERATION WHICH ACCOMPANIES AGEING 审中-公开
标题翻译：饮料适合延缓伴随老化的细胞变性
公开(公告)号：WO2008037740A3
公开(公告)日：2008-05-15
申请号：PCT/EP2007060216
申请日：2007-09-26
申请人： GENALTA S R L , BERNASCONI SARA , BERTINI IVANO , LUCCIOLA ISIDORO , LUCHINAT CLAUDIO , QUATTRONE ALESSANDRO , SCAPAGNINI GIOVANNI
发明人： BERNASCONI SARA , BERTINI IVANO , LUCCIOLA ISIDORO , LUCHINAT CLAUDIO , QUATTRONE ALESSANDRO , SCAPAGNINI GIOVANNI
IPC分类号： A23L1/30 , A23L1/305 , A23L2/52
CPC分类号： A23L2/52 , A23L33/105 , A23L33/18 , A23V2002/00 , A23V2250/1642 , A23V2250/161 , A23V2250/032 , A23V2200/322 , A23V2200/302 , A23V2250/2116 , A23V2250/7056 , A23V2250/72
摘要： The object of the present invention is a beverage suitable to retard the cellular degeneration which accompanies ageing, comprising epigallocatechin gallate and L-carnosine, possibly associated with other active components.
摘要翻译：本发明的目的是适合于延缓伴随老化的细胞变性的饮料，其包含表没食子儿茶素没食子酸酯和L-肌肽，可能与其它活性组分相关。

3. 发明申请

WO2009004409A1 PREPARATIONS CONTANING MICROORGANISMS 审中-公开
标题翻译：微生物制剂
公开(公告)号：WO2009004409A1
公开(公告)日：2009-01-08
申请号：PCT/IB2007/052998
申请日：2007-07-30
申请人： SIRC S.p.A. Natural & Dietetic Foods , MEZZINA, Cosmo , SCAPAGNINI, Giovanni
发明人： MEZZINA, Cosmo , SCAPAGNINI, Giovanni
IPC分类号： A23L1/00 , A23L1/03 , A23L1/053 , A61K9/28
CPC分类号： A61K9/286 , A23L29/065 , A23L33/135 , A23L33/16 , A23P20/10 , A61K9/2086 , A61K9/288
摘要： A coating film obtained from an aqueous composition comprising (parts by weight): 100 parts of live micro-organisms, 5.4-6.1 parts of organic material comprising selenium, 130-160 parts of natural or semisynthetic elastomeric membranes, and natural organic acids, said composition having a weight ratio between the water and the natural or semisynthetic membrane that ranges between 1.5:1 and 2.5:1, a pH that ranges between 4 and 6.5, and a viscosity equal to or less than 10,000 centipoise. A process for obtaining said coating film, comprising heating of the material to be coated, which is contained in the receptacle of an appliance for coating tablets, at a temperature below the temperature at which the micro-organisms present in the aqueous composition die; pressure reduction in said receptacle to a pressure in the receptacle which ranges between -1 and -2 bars, and spraying of said aqueous composition onto the material to be coated, the nebulisation pressure of said composition being 0.2 to 0.9 bar.
摘要翻译：由包含（重量份）的水性组合物得到的涂膜：100份活微生物，5.4-6.1份包含硒的有机材料，130-160份天然或半合成弹性体膜和天然有机酸，所述水和天然或半合成膜之间的重量比在1.5:1和2.5:1之间，pH范围在4和6.5之间，粘度等于或小于10,000厘泊的组合物。一种获得所述涂膜的方法，包括在低于存在于水性组合物模具中的微生物的温度的温度下加热包含在用于涂布片剂的器具的容器中的待涂覆材料; 所述容器中的压力降低到容器中的压力在-1和-2巴之间，并且将所述水性组合物喷射到待涂覆的材料上，所述组合物的雾化压力为0.2至0.9巴。

4. 发明申请

WO2008007321A3 CROSS-LINKED CHITOSAN AND PROCESS TO CROSS-LINK 审中-公开
公开(公告)号：WO2008007321A3
公开(公告)日：2008-01-17
申请号：PCT/IB2007/052659
申请日：2007-07-06
申请人： SIRC SPA NATURAL & DIETETIC FOODS , MEZZINA, Cosmo , SCAPAGNINI, Giovanni , VOLPATO, Ivo , BIZZINI, Bernard , FRANCHI, Giovanni
发明人： MEZZINA, Cosmo , SCAPAGNINI, Giovanni , VOLPATO, Ivo , BIZZINI, Bernard , FRANCHI, Giovanni
IPC分类号： C08B37/08 , C08J3/24
摘要： The present invention relates to Chitosans in crosslinked form wherein the crosslink derives from the reaction of said chitosans with a crosslinker chosen from among the group of aliphatic aldehydes, and to a Chitosan crosslinking process comprising the following stages: 1) suspend chitosan in a buffer solution having a pH that ranges between 7.5 and 9.5, preferably between 8.0 and 9.0, and more preferably between 8.1 and 8.3 (suspension 1); 2) place suspension (1) in contact with an aliphatic aldehyde as crosslinker and leave to react for 1 to 24 hours at a temperature of between 15- and 40 -C (suspension 2); and possibly: 3) treat suspension (2) with an organic amine compound.

5. 发明申请

WO2014040632A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF ACUTE AND RECURRENT URINARY TRACT INFECTIONS 审中-公开
标题翻译：预防和治疗急性和复发性尿路感染的组合物
公开(公告)号：WO2014040632A1
公开(公告)日：2014-03-20
申请号：PCT/EP2012/068089
申请日：2012-09-14
申请人： BETA PHARMA S.A. , SFERRA, Daniela , RUSSO, Valentina , VERGALITO, Franca , FRANCESCHINI, Debora , MANGANO, Katia , SCAPAGNINI, Giovanni , DI MARCO, Roberto , LONGO, Sonia
发明人： SFERRA, Daniela , RUSSO, Valentina , VERGALITO, Franca , FRANCESCHINI, Debora , MANGANO, Katia , SCAPAGNINI, Giovanni , DI MARCO, Roberto , LONGO, Sonia
IPC分类号： A61K36/185 , A61K36/29 , A61K36/756 , A61K36/59 , A61K36/53 , A61K36/718 , A61K36/66
CPC分类号： A61K36/29 , A61K36/185 , A61K36/53 , A61K36/59 , A61K36/66 , A61K36/718 , A61K36/756 , Y02A50/473
摘要： The present invention relates, in one aspect, to a composition or dietary supplement comprising a synergistic association of Arbutin and Berberine, optionally including an additional active ingredient of vegetal origin selected from Arbutin, Forskolin and mixtures thereof, for improving the health of the urinary tract and preventing or treating acute and recurrent urinary tract infections (UTI).
摘要翻译：本发明在一个方面涉及包含熊果苷和小檗碱的协同关联的组合物或膳食补充剂，任选地包括选自熊果苷，福斯克林及其混合物的植物来源的额外活性成分，以改善尿道的健康以及预防或治疗急性和复发性尿路感染（UTI）。

6. 发明申请

WO2012107905A1 COMPOSITION FOR USE IN THE TREATMENT OF MENOPAUSE PROBLEMS/DISORDERS AND IN THE TREATMENT OF GENERAL AGING OF THE ORGANISM. 审中-公开
标题翻译：用于治疗器官问题/病症以及治疗有机体一般老化的组合物。
公开(公告)号：WO2012107905A1
公开(公告)日：2012-08-16
申请号：PCT/IB2012/050615
申请日：2012-02-10
申请人： PALADIN PHARMA S.P.A. , SCAPAGNINI, Giovanni , DAVINELLI, Sergio , VISENTIN, Manuela , RUFFINENGO, Edoardo
发明人： SCAPAGNINI, Giovanni , DAVINELLI, Sergio , VISENTIN, Manuela , RUFFINENGO, Edoardo
IPC分类号： A61K31/05 , A61K31/353 , A61K36/48 , A61K36/87 , A61P15/12
CPC分类号： A61K36/48 , A23L33/10 , A23L33/105 , A23V2002/00 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K31/05 , A61K31/353 , A61K36/87 , C12P17/06 , A61K2300/00 , A23V2200/302 , A23V2200/31 , A23V2250/21 , A23V2250/21172
摘要： The invention concerns a composition for the prevention and/or the treatment of menopausal syndrome and/or of aging comprising an association of an equolbased active metabolite of daidzein with resveratrol, in an edible carrier or excipient. The invention composition may be in the form of a nutraceutical or pharmaceutical preparation.
摘要翻译：本发明涉及用于预防和/或治疗更年期综合征和/或老化的组合物，其包含在可食用的载体或赋形剂中的大黄素与白藜芦醇的血浆活性代谢物缔合。本发明组合物可以是营养药物或药物制剂的形式。

7. 发明申请

WO2008010172A3 CHITINS AND CHITOSANS IN AN ACTIVATED FORM AND THEIR SLIMMING, HYPOGLYCAEMIC, HYPOLIPIDAEMIC PROPERTIES 审中-公开
标题翻译：活性物质中的CHIOS和CHITOSANS及其沉淀，高分子化合物，高分子性质
公开(公告)号：WO2008010172A3
公开(公告)日：2008-03-27
申请号：PCT/IB2007052803
申请日：2007-07-13
申请人： SIRC SPA NATURAL & DIETETIC FO , MEZZINA COSMO , SCAPAGNINI GIOVANNI , VOLPATO IVO , BIZZINI BERNARD , FRANCHI GIOVANNI
发明人： MEZZINA COSMO , SCAPAGNINI GIOVANNI , VOLPATO IVO , BIZZINI BERNARD , FRANCHI GIOVANNI
IPC分类号： C08B37/08 , A23L1/308
CPC分类号： C08L5/08 , A23L29/275 , A23L33/17 , A23V2002/00 , C08B37/003 , A23V2200/332 , A23V2200/328 , A23V2250/542
摘要： A process for activating D-glucosamine polymers chosen from among chitins, chitosans and crosslinked chitosans and the activated D-glucosamine polymers obtained from the said process. The activation process comprises the following stages: a) treating the polymers with an 0.5 to 3 N solution of a strong base, and b) heating the suspension to a temperature of between 80 and 110°C and maintaining said temperature for between 2 and 10 minutes. A diet supplement including a nutritional preparation including the said activated polymers. The said diet supplements and nutritional preparations are to be used for the treatment of obesity, hyperlipidaemia, hyperglycaemia and diabetes.
摘要翻译：一种用于激活选自壳多糖，壳聚糖和交联的壳聚糖中的D-葡糖胺聚合物的方法和从所述方法获得的活化的D-葡糖胺聚合物。活化过程包括以下步骤：a）用强碱的0.5-3N溶液处理聚合物，和b）将悬浮液加热到80-110℃的温度，并将所述温度保持在2和10之间分钟。一种饮食补充剂，包括包含所述活化聚合物的营养制剂。所述饮食补充剂和营养制剂将用于治疗肥胖，高脂血症，高血糖症和糖尿病。

8. 发明申请

WO2008010172A2 CHITINS AND CHITOSANS IN AN ACTIVATED FORM AND THEIR SLIMMING, HYPOGLYCAEMIC, HYPOLIPIDAEMIC PROPERTIES 审中-公开
标题翻译：活性物质中的CHIOS和CHITOSANS及其沉淀，高分子化合物，高分子性质
公开(公告)号：WO2008010172A2
公开(公告)日：2008-01-24
申请号：PCT/IB2007/052803
申请日：2007-07-13
申请人： SIRC SPA NATURAL & DIETETIC FOODS , MEZZINA, Cosmo , SCAPAGNINI, Giovanni , VOLPATO, Ivo , BIZZINI, Bernard , FRANCHI, Giovanni
发明人： MEZZINA, Cosmo , SCAPAGNINI, Giovanni , VOLPATO, Ivo , BIZZINI, Bernard , FRANCHI, Giovanni
IPC分类号： C08B37/08 , A23L1/308
CPC分类号： C08L5/08 , A23L29/275 , A23L33/17 , A23V2002/00 , C08B37/003 , A23V2200/332 , A23V2200/328 , A23V2250/542
摘要： A process for activating D-glucosamine polymers chosen from among chitins, chitosans and crosslinked chitosans and the activated D-glucosamine polymers obtained from the said process. The activation process comprises the following stages: a) treating the polymers with an 0.5 to 3 N solution of a strong base, and b) heating the suspension to a temperature of between 80 and 11O0C and maintaining said temperature for between 2 and 10 minutes. A diet supplement including a nutritional preparation including the said activated polymers. The said diet supplements and nutritional preparations are to be used for the treatment of obesity, hyperlipidaemia, hyperglycaemia and diabetes.
摘要翻译：一种用于激活选自壳多糖，壳聚糖和交联的壳聚糖中的D-葡糖胺聚合物的方法和从所述方法获得的活化的D-葡糖胺聚合物。活化过程包括以下步骤：a）用0.5-3N的强碱溶液处理聚合物，和b）将悬浮液加热到80-110℃的温度，并保持所述温度2至10分钟。一种饮食补充剂，包括包含所述活化聚合物的营养制剂。所述饮食补充剂和营养制剂将用于治疗肥胖，高脂血症，高血糖症和糖尿病。

9. 发明申请

WO2008007321A2 CROSS-LINKED CHITOSAN AND PROCESS TO CROSS-LINK 审中-公开
标题翻译：交叉链接的CHITOSAN和交叉过程
公开(公告)号：WO2008007321A2
公开(公告)日：2008-01-17
申请号：PCT/IB2007052659
申请日：2007-07-06
申请人： SIRC SPA NATURAL & DIETETIC FO , MEZZINA COSMO , SCAPAGNINI GIOVANNI , VOLPATO IVO , BIZZINI BERNARD , FRANCHI GIOVANNI
发明人： MEZZINA COSMO , SCAPAGNINI GIOVANNI , VOLPATO IVO , BIZZINI BERNARD , FRANCHI GIOVANNI
IPC分类号： C08B37/08
CPC分类号： C08B37/003
摘要： Chitosans in crosslinked form wherein the crosslink derives from the reaction of said chitosans with a crosslinker chosen from among the group of aliphatic aldehydes. Chitosan crosslinking process comprising the following stages: 1) suspend chitosan in a buffer solution having a pH that ranges between 7.5 and 9.5, preferably between 8.0 and 9.0, and more preferably between 8.1 and 8.3 (suspension 1); 2) place suspension (1) in contact with an aliphatic aldehyde as crosslinker and leave to react for 1 to 24 hours at a temperature of between 15° and 40°C (suspension 2); and possibly: 3) treat suspension (2) with an organic amine compound.
摘要翻译：交联形式的壳聚糖，其中交联衍生自所述壳聚糖与选自脂族醛的交联剂的反应。壳聚糖交联方法包括以下步骤：1）将壳聚糖悬浮在pH范围为7.5至9.5，优选8.0至9.0，更优选8.1至8.3（悬浮液1）的缓冲溶液中; 2）将悬浮液（1）与脂肪族醛作为交联剂接触，并在15〜40℃（悬浮液2）的温度下反应1〜24小时。并且可能：3）用有机胺化合物处理悬浮液（2）。

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