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1. 发明申请

WO2013039717A3 METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES 审中-公开
标题翻译：标记含有硫酸的蛋白质和肽的方法
公开(公告)号：WO2013039717A3
公开(公告)日：2014-05-08
申请号：PCT/US2012053376
申请日：2012-08-31
申请人： UNIV WAKE FOREST HEALTH SCIENCES , FURDUI CRISTINA M , TSANG ALLEN W , QIAN JIANG
发明人： FURDUI CRISTINA M , TSANG ALLEN W , QIAN JIANG
IPC分类号： G01N33/00 , G01N24/00
CPC分类号： G01N33/58 , C07C69/738 , C07K1/1077 , C07K1/13 , G01N1/30 , G01N33/64 , Y10T436/18
摘要： A method of labeling a sulfenic acid (-SOH) group of a cysteine residue in a protein or peptide, comprises contacting said protein or peptide with a beta-ketoester to covalently couple said beta-ketoester to said cysteine residue and form a beta-ketoester-labeled cysteine residue in said protein or peptide.
摘要翻译：标记蛋白质或肽中的半胱氨酸残基的亚磺酸（-SOH）基团的方法包括使所述蛋白质或肽与β-酮酯接触以将所述β-酮酯共价连接到所述半胱氨酸残基并形成β-酮酯标记的所述蛋白质或肽中的半胱氨酸残基。

2. 发明申请

WO2009108504A3 UNIVERSAL LANGUAGE INPUT 审中-公开
标题翻译：通用语言输入
公开(公告)号：WO2009108504A3
公开(公告)日：2009-10-22
申请号：PCT/US2009033834
申请日：2009-02-11
申请人： GOOGLE INC , QIAN JIANG , ZHANG LEI
发明人： QIAN JIANG , ZHANG LEI
IPC分类号： G06F17/30
CPC分类号： G06F17/289 , G06F17/30669
摘要： Systems, methods, and apparatuses including computer program products for universal language input are provided. In one implementation, a method is provided. The method includes using a first application or operating system component to detect user input to an application interface of a second application. The method also includes, as input is detected in the application interface, automatically using the first application to provide one or more translations of the input including, sending the input to a translation model, receiving translated input from the translation model, and sending the translated input to the application interface of the second application.
摘要翻译：提供了包括用于通用语言输入的计算机程序产品的系统，方法和装置。在一个实现中，提供了一种方法。该方法包括使用第一应用或操作系统组件来检测对第二应用的应用接口的用户输入。该方法还包括当在应用程序界面中检测到输入时，自动使用第一应用程序提供输入的一个或多个翻译，包括将输入发送到翻译模型，从翻译模型接收翻译输入，并发送翻译的输入到第二个应用程序的应用程序界面。

3. 发明申请

WO2013039717A2 METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES 审中-公开
标题翻译：标记含有硫酸的蛋白质和肽的方法
公开(公告)号：WO2013039717A2
公开(公告)日：2013-03-21
申请号：PCT/US2012/053376
申请日：2012-08-31
申请人： WAKE FOREST UNIVERSITY HEALTH SCIENCES , FURDUI, Cristina M. , TSANG, Allen W. , QIAN, Jiang
发明人： FURDUI, Cristina M. , TSANG, Allen W. , QIAN, Jiang
IPC分类号： C12N9/00 , C07K1/13
CPC分类号： G01N33/58 , C07C69/738 , C07K1/1077 , C07K1/13 , G01N1/30 , G01N33/64 , Y10T436/18
摘要： A method of labeling a sulfenic acid (-SOH) group of a cysteine residue in a protein or peptide, comprises contacting said protein or peptide with a beta-ketoester to covalently couple said beta-ketoester to said cysteine residue and form a beta-ketoester-labeled cysteine residue in said protein or peptide.
摘要翻译：标记蛋白质或肽中的半胱氨酸残基的亚磺酸（-SOH）基团的方法包括使所述蛋白质或肽与β-酮酯接触以将所述β-酮酯共价连接到所述半胱氨酸残基并形成β-酮酯标记的所述蛋白质或肽中的半胱氨酸残基。

4. 发明申请

WO2012170970A2 ELEMENT CONTAINING THERMALLY STABLE POLYCRYSTALLINE DIAMOND MATERIAL AND METHODS AND ASSEMBLIES FOR FORMATION THEREOF 审中-公开
标题翻译：包含热稳定的多晶金刚石材料的元件及其形成方法及组件
公开(公告)号：WO2012170970A2
公开(公告)日：2012-12-13
申请号：PCT/US2012041778
申请日：2012-06-09
申请人： HALLIBURTON ENERGY SERV INC , ATKINS BRIAN , ANDERLE SETH G , ARFELE ROBERT W , LADI RAM L , LINFORD BRANDON PAUL , WIGGINS JASON KEITH , NGUYEN KEVIN DUY , QIAN JIANG , BERTAGNOLLI KENNETH EUGENE , SCOTT SHAWN CASEY , MUKHOPADHYAY DEBKUMAR , VAIL MICHAEL ALEXANDER
发明人： ATKINS BRIAN , ANDERLE SETH G , ARFELE ROBERT W , LADI RAM L , LINFORD BRANDON PAUL , WIGGINS JASON KEITH , NGUYEN KEVIN DUY , QIAN JIANG , BERTAGNOLLI KENNETH EUGENE , SCOTT SHAWN CASEY , MUKHOPADHYAY DEBKUMAR , VAIL MICHAEL ALEXANDER
IPC分类号： E21B10/46 , C09K3/14
CPC分类号： C22C26/00 , B22F2999/00 , C22C2204/00 , E21B10/5735 , C22C1/08 , C22C1/1094 , B22F2003/244
摘要： The disclosure provides a super abrasive element containing a substantially catalyst-free thermally stable polycrystalline diamond (TSP) body having pores and a contact surface, a base adjacent the contact surface of the TSP body; and an infiltrant material infiltrated in the base and in the pores of the TSP body at the contact surface. The disclosure additionally provides earth-boring drill bits and other devices containing such super abrasive elements. The disclosure further provides methods and mold assemblies for forming such super abrasive elements via infiltration and hot press methods
摘要翻译：本公开提供了一种含有基本上无催化剂的热稳定多晶金刚石（TSP）体的超级研磨元件，其具有孔和接触表面，邻近TSP体的接触表面的基底; 以及在接触表面浸渍在TSP体的基体和孔中的渗透材料。本公开另外提供了钻孔钻头和包含这种超级研磨元件的其它装置。本公开进一步提供了通过渗透和热压法形成这种超级研磨元件的方法和模具组件

5. 发明申请

WO2008030644A2 LOCAL SEARCH USING ADDRESS COMPLETION 审中-公开
标题翻译：本地搜索使用地址完成
公开(公告)号：WO2008030644A2
公开(公告)日：2008-03-13
申请号：PCT/US2007/069756
申请日：2007-05-25
申请人： GOOGLE INC. , QIAN, Jiang
发明人： QIAN, Jiang
IPC分类号： G06F17/00
CPC分类号： G06F17/3087
摘要： A local search server receives queries for information about businesses from clients. The local search server searches a local information database for information about a business and reports the information about the business to the client that requested it. Sometimes, the database lacks complete information for the business. For example, the database might be missing the street number for the business. The local search server obtains the missing information by interfacing with a search engine and searching for hosted documents about the business. The local search server receives snippets of text from the documents. The local search server applies one or more heuristics to the text snippets to determine the missing information. The missing information is saved in the local information database.
摘要翻译：本地搜索服务器从客户端接收有关企业信息的查询。本地搜索服务器在本地信息数据库中搜索有关业务的信息，并向请求的客户端报告有关业务的信息。有时，数据库缺少业务的完整信息。例如，数据库可能缺少该业务的街道号码。本地搜索服务器通过与搜索引擎连接并搜索关于业务的托管文档来获取丢失的信息。本地搜索服务器从文档中接收文本片段。本地搜索服务器将一个或多个启发式应用于文本片段，以确定缺少的信息。缺少的信息保存在本地信息数据库中。

6. 发明申请

WO2013101352A1 METHOD AND SYSTEM FOR GENERATING A MULTI-DIMENSIONAL SURFACE MODEL OF A GEOMETRIC STRUCTURE 审中-公开
标题翻译：用于产生几何结构的多维表面模型的方法和系统
公开(公告)号：WO2013101352A1
公开(公告)日：2013-07-04
申请号：PCT/US2012/065201
申请日：2012-11-15
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , CARBONERA, Carlos , VYLKOV, Vasily , STARKS, Daniel R. , QIAN, Jiang , VOTH, Eric, J.
发明人： CARBONERA, Carlos , VYLKOV, Vasily , STARKS, Daniel R. , QIAN, Jiang , VOTH, Eric, J.
IPC分类号： G06F17/50 , G06F17/00
CPC分类号： G06T17/20 , G06T2200/08 , G06T2210/12 , G06T2210/41
摘要： [A method of generating a multi-dimensional surface model of a geometric structure is provided. The method comprises acquiring a set of location data points comprising a plurality of location data points corresponding to respective locations on the surface of a region of the geometric structure. The method further comprises defining a bounding box containing each location data point of the set of location data points, and constructing a voxel grid based on the bounding box, wherein the voxel grid comprises a plurality of voxels. The method still further comprises extracting a multi-faceted surface model from certain of the plurality of voxels of the voxel grid using, for example, an alpha-hull approximation technique. The method may further comprise one or more of decimating and smoothing the surface of the multi-faceted surface model. A system comprising a processing apparatus for performing the aforedescribed method is also provided.
摘要翻译：提供了一种产生几何结构的多维表面模型的方法。该方法包括获取一组位置数据点，该位置数据点包括对应于几何结构区域的表面上的相应位置的多个位置数据点。所述方法还包括定义包含所述一组位置数据点中的每个位置数据点的边界框，以及基于所述边界框构建体素网格，其中所述体素网格包括多个体素。该方法还包括使用例如α壳体近似技术从体素网格的多个体素中的某些特征提取多面表面模型。该方法还可以包括对多面表面模型的表面进行抽取和平滑处理的一个或多个。还提供了一种包括用于执行上述方法的处理装置的系统。

7. 发明申请

WO2012128948A1 POLYCRYSTALLINE DIAMOND COMPACT INCLUDING A CARBONATE-CATALYZED POLYCRYSTALLINE DIAMOND BODY AND APPLICATIONS THEREFOR 审中-公开
标题翻译：多晶金刚石，包括碳酸钙催化的多晶金刚石体及其应用
公开(公告)号：WO2012128948A1
公开(公告)日：2012-09-27
申请号：PCT/US2012/028051
申请日：2012-03-07
申请人： US SYNTHETIC CORPORATION , QIAN, Jiang , BERTAGNOLLI, Kenneth, E. , GONZALEZ, Jair, J. , COOLEY, Craig, H.
发明人： QIAN, Jiang , BERTAGNOLLI, Kenneth, E. , GONZALEZ, Jair, J. , COOLEY, Craig, H.
IPC分类号： B22F5/00 , C22C26/00 , B24D18/00 , C09K3/14 , E21B10/46
CPC分类号： C22C26/00 , B22F5/00 , C09K3/1409 , E21B10/567 , F16C33/043 , F16C33/26 , F16C2206/04 , F16C2352/00
摘要： In an embodiment, a polycrystalline diamond compact ("PDC") includes a substrate and a pre-sintered polycrystalline diamond ("PCD") table bonded to the substrate. The pre-sintered PCD table includes an upper surface, a back surface bonded to the substrate, and at least one lateral surface extending between the upper surface and the back surface. The pre-sintered PCD table includes a region including at least a residual amount of at least one interstitial constituent disposed in at least a portion of the interstitial regions thereof, and a bonding region. The at least one interstitial constituent includes at least one metal carbonate and/or at least one metal oxide. The region extends inwardly from the upper surface and the at least one lateral surface.
摘要翻译：在一个实施方案中，多晶金刚石复合体（“PDC”）包括基底和与基底结合的预烧结多晶金刚石（“PCD”）台。预烧结PCD台包括上表面，与基底结合的后表面，以及在上表面和后表面之间延伸的至少一个侧表面。预烧结PCD表包括至少包括设置在其间隙区域的至少一部分中的至少一个间隙成分的剩余量的区域和接合区域。至少一种间隙成分包括至少一种金属碳酸盐和/或至少一种金属氧化物。该区域从上表面和至少一个侧表面向内延伸。

8. 发明申请

WO2010124424A1 SHORT POINT-OF-INTEREST TITLE GENERATION 审中-公开
标题翻译：短期利益标题生成
公开(公告)号：WO2010124424A1
公开(公告)日：2010-11-04
申请号：PCT/CN2009/000475
申请日：2009-04-29
申请人： GOOGLE INC. , QIAN, Jiang , ZHOU, Vincent , ZHENG, Bo , ZHENG, Yu
发明人： QIAN, Jiang , ZHOU, Vincent , ZHENG, Bo , ZHENG, Yu
IPC分类号： G06F17/30
CPC分类号： G06F17/2745
摘要： Short POI titles are generated by removing unnecessary administrative area prefixes from existing POI titles and replacing necessary administrative area prefixes with shorter aliases. Administrative area prefixes are identified and analyzed to determine whether they are necessary. The analysis includes determining (1) whether the remainders with the prefixes excluded include a common suffix as a prefix, and (2) whether the remainders are unique in an applicable metropolis area. If a remainder does not include as a prefix a common suffix and is unique in the applicable metropolis area, the corresponding prefix is determined unnecessary and removed from the existing POI title to generate a short POI title. Otherwise, the corresponding prefix is determined necessary and replaced with a shorter alias to generate a short POI title.
摘要翻译：通过从现有POI标题中删除不必要的管理区域前缀，并用较短的别名替换必要的管理区域前缀来生成简短的POI标题。对行政区域前缀进行识别和分析，以确定它们是否必要。分析包括确定（1）排除前缀的余数是否包括作为前缀的公共后缀，以及（2）在适用的大都会区域中剩余部分是否是唯一的。如果余数不包括作为前缀的公共后缀，并且在适用的大都市区域中是唯一的，则相应的前缀被确定为不必要的并且从现有POI标题中移除以生成短的POI标题。否则，相应的前缀被确定为必需，并用较短的别名替换以生成短的POI标题。

9. 发明申请

WO2010039346A1 POLYCRYSTALLINE DIAMOND, POLYCRYSTALLINE DIAMOND COMPACT, METHOD OF FABRICATING SAME, AND VARIOUS APPLICATIONS 审中-公开
标题翻译：多晶金刚石，多晶金刚石，其制造方法及各种应用
公开(公告)号：WO2010039346A1
公开(公告)日：2010-04-08
申请号：PCT/US2009/054398
申请日：2009-08-20
申请人： US SYNTHETIC CORPORATION , BERTAGNOLLI, Kenneth, E. , QIAN, Jiang , WIGGINS, Jason , VAIL, Michael, A. , MUKHOPADHYAY, Debkumar
发明人： BERTAGNOLLI, Kenneth, E. , QIAN, Jiang , WIGGINS, Jason , VAIL, Michael, A. , MUKHOPADHYAY, Debkumar
IPC分类号： C22C26/00
CPC分类号： C04B37/001 , B21C3/025 , B24D18/0009 , C04B2237/36 , C04B2237/363 , C22C26/00 , E21B10/567 , F16C17/02 , F16C17/04 , F16C33/043 , F16C33/26 , F16C2206/04 , F16C2206/82 , F16C2220/20 , F16C2240/40 , F16C2240/48 , F16C2352/00 , G01N27/72 , G01N27/80 , Y10T428/24058 , Y10T428/24997 , Y10T428/25 , Y10T428/252 , Y10T428/30
摘要： Embodiments of the invention relate to polycrystalline diamond ("PCD") exhibiting enhanced diamond-to-diamond bonding. In an embodiment, PCD includes a plurality of diamond grains defining a plurality of interstitial regions. A metal-solvent catalyst occupies at least a portion of the plurality of interstitial regions. The plurality of diamond grains and the metal-solvent catalyst collectively exhibit a coercivity of about 115 Oersteds ("Oe") or more and a specific magnetic saturation of about 15 Gauss cm3/grams ("G cm 3 /g") or less. Other embodiments are directed to polycrystalline diamond compacts ("PDCs") employing such PCD, methods of forming PCD and PDCs, and various applications for such PCD and PDCs in rotary drill bits, bearing apparatuses, and wire-drawing dies.
摘要翻译：本发明的实施方案涉及显示增强的金刚石与金刚石结合的多晶金刚石（“PCD”）。在一个实施例中，PCD包括限定多个间隙区域的多个金刚石晶粒。金属溶剂催化剂占据多个间隙区域的至少一部分。多个金刚石晶粒和金属 - 溶剂催化剂共同表现出约115奥斯特（“Oe”）或更高的矫顽力和约15高斯cm 3 /克（“G cm 3 / g”）或更小的特定磁饱和度。其他实施方案涉及采用这种PCD的多晶金刚石压块（“PDC”），形成PCD和PDC的方法，以及用于旋转钻头，轴承装置和拉丝模具中的这种PCD和PDC的各种应用。

10. 发明申请

WO2013012919A1 POLYCRYSTALLINE DIAMOND COMPACT INCLUDING A CARBONATE-CATALYSED POLYCRYSTALLINE DIAMOND TABLE AND APPLICATIONS THEREFOR 审中-公开
标题翻译：多晶金刚石，包括碳酸钙催化的多晶金刚石表及其应用
公开(公告)号：WO2013012919A1
公开(公告)日：2013-01-24
申请号：PCT/US2012/047191
申请日：2012-07-18
申请人： US SYNTHETIC CORPORATION , QIAN, Jiang , MCMURRAY, Eugene, C. , MUKHOPADHYAY, Debkumar , WIGGINS, Jason, K. , VAIL, Michael, A. , BERTAGNOLLI, Kenneth, E.
发明人： QIAN, Jiang , MCMURRAY, Eugene, C. , MUKHOPADHYAY, Debkumar , WIGGINS, Jason, K. , VAIL, Michael, A. , BERTAGNOLLI, Kenneth, E.
IPC分类号： B22F7/06 , C22C26/00 , E21B10/567 , B23B27/00
CPC分类号： B24D3/10 , B22F7/062 , B22F2005/001 , B24D18/0009 , C22C26/00 , E21B10/54 , E21B10/56 , E21B10/567 , F16C33/043 , F16C33/108 , F16C2352/00 , Y10T408/89
摘要： In an embodiment, a polycrystalline diamond compact includes a substrate and a preformed polycrystalline diamond table bonded to the substrate. The table includes bonded diamond grains defining interstitial regions. The table includes an upper surface, a back surface bonded to the substrate, and at least one lateral surface extending therebetween. The table includes a first region extending inwardly from the upper surface and the lateral surface. The first region exhibits a first interstitial region concentration and includes at least one interstitial constituent disposed therein, which may be present in at least a residual amount and includes at least one metal carbonate and/or at least one metal oxide. The table includes a second bonding region adjacent to the substrate that extends inwardly from the back surface. The second bonding region exhibits a second interstitial region concentration that is greater than the first interstitial region concentration and includes a metallic infiltrant therein.
摘要翻译：在一个实施例中，多晶金刚石致密体包括基底和结合到基底的预成型多晶金刚石台。该表包括定义间隙区域的结合金刚石颗粒。桌子包括上表面，与表面粘合的后表面，以及在其间延伸的至少一个侧表面。桌子包括从上表面和侧表面向内延伸的第一区域。第一区域表现出第一间隙区域浓度并且包括至少一个置于其中的间隙成分，其可以以至少残留量存在并且包括至少一种金属碳酸盐和/或至少一种金属氧化物。桌子包括与衬底相邻的第二接合区域，其从后表面向内延伸。第二结合区域表现出比第一间隙区域浓度大的第二间隙区域浓度，并且其中包括金属渗透剂。

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