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1. 发明申请

WO2014150574A1 METHOD FOR REMOVING DUST FROM SEEDS 审中-公开
标题翻译：从种子中去除粪便的方法
公开(公告)号：WO2014150574A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/023666
申请日：2014-03-11
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , DAMMEN, Michael K. , MEYER, Timothy P.
发明人： DAMMEN, Michael K. , MEYER, Timothy P.
IPC分类号： A01C1/00 , A01C1/06
CPC分类号： A01C1/06 , A01C1/00
摘要： Embodiments of a technique are provided for removing dust from treated seeds. The method includes applying a treatment to a number of seeds at a seed treatment station (10) and at least partially drying the seeds at the treatment station (10). The partially dried seeds may then be conveyed through a conveying station (20) from the treatment station (10) to an output area (30). Air may be directed through an inlet of the conveying station (20), where the directed air is configured to remove non-seed particles from the seeds. Furthermore, air may be filtered through an outlet of the conveying station (20) to capture the removed non-seed particles using a filtering system. In some cases, an initial temperature of the air may be controlled to optimize the dust removal process, such as by heating and/or chilling the air.
摘要翻译：提供了用于从处理过的种子去除灰尘的技术的实施例。该方法包括在种子处理站（10）处对许多种子进行处理并且在处理站（10）处至少部分地干燥种子。然后可将部分干燥的种子通过输送站（20）从处理站（10）输送到输出区域（30）。空气可以被引导通过输送站（20）的入口，其中定向空气被配置为从种子去除非种子颗粒。此外，可以通过输送站（20）的出口过滤空气，以使用过滤系统捕获去除的非种子颗粒。在一些情况下，可以控制空气的初始温度以优化除尘过程，例如通过加热和/或冷却空气。

2. 发明申请

WO2013116547A1 IMPLANTABLE DEVICE AND METHODS FOR DIAGNOSING HEART FAILURE USING BIOMARKER PANEL DATA 审中-公开
标题翻译：使用生物标记面板数据诊断心脏失败的可植入设备和方法
公开(公告)号：WO2013116547A1
公开(公告)日：2013-08-08
申请号：PCT/US2013/024189
申请日：2013-01-31
申请人： CARDIAC PACEMAKERS, INC. , STOLEN, Craig, M. , MEDICAL UNIVERSITY OF SOUTH CAROLINA , MEYER, Timothy, E. , SETH, Milan , SPINALE, Francis, G. , WOLD, Nicholas, David
发明人： STOLEN, Craig, M. , MEYER, Timothy, E. , SETH, Milan , SPINALE, Francis, G. , WOLD, Nicholas, David
IPC分类号： A61N1/362 , G01N33/68
CPC分类号： A61B5/14546 , A61B5/14503 , A61B5/4836 , A61B5/686 , A61B5/6869 , A61B5/7282 , A61N1/3627 , A61N1/36557 , A61N1/3956 , G01N33/6893 , G01N2800/32 , G01N2800/325 , G01N2800/326 , G01N2800/50
摘要： Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data and related medical devices and methods, amongst other things. An embodiment can include an implantable medical device including a processor, the implantable medical device configured to diagnose a patient based at least in part on quantified levels of one or more of a panel of biomarkers. The panel of biomarkers including at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. An embodiment can include a method of screening patients. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include analyzing the quantified levels. In an embodiment, the disclosure can include a method of diagnosing a patient. Other embodiments are also included herein.
摘要翻译：本公开的实施例涉及用于利用生物标志物面板数据的系统和方法以及相关的医疗装置和方法。实施例可以包括可植入医疗装置，其包括处理器，所述可植入医疗装置被配置为至少部分地基于面板生物标志物中的一个或多个的量化水平来诊断患者。生物标志物组包括选自CRP，SGP-130，sIL-2R，sTNFR-II，IFNg，BNP，sST2，MMP-2，MMP-9，TIMP-1，TIMP-2， TIMP-4。一个实施方案可以包括筛选患者的方法。该方法可以包括定量患者生物样品中一组或多种生物标志物的水平。该方法还可以包括分析量化水平。在一个实施例中，本公开可以包括诊断患者的方法。本文还包括其它实施例。

3. 发明申请

WO2010021825A1 METHOD AND SYSTEM FOR DATA DRIVEN MANAGEMENT OF INDIVIDUAL SEEDS 审中-公开
标题翻译：个体种子数据驱动管理方法与系统
公开(公告)号：WO2010021825A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/052472
申请日：2009-07-31
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , COPE, Jason, M. , HOEKSTRA, John, C. , DIMOND, James, D. , BECKER, Steven, M. , BOWEN, David, E. , MEYER, Timothy, P. , HUNTER, James, L. , STOTT, Barry, L. , STEENHOEK, Loren , KELSICK, Jason, J. , SMITH, David, C. , MONGAN, Joshua L.
发明人： COPE, Jason, M. , HOEKSTRA, John, C. , DIMOND, James, D. , BECKER, Steven, M. , BOWEN, David, E. , MEYER, Timothy, P. , HUNTER, James, L. , STOTT, Barry, L. , STEENHOEK, Loren , KELSICK, Jason, J. , SMITH, David, C. , MONGAN, Joshua L.
IPC分类号： A01H1/00
CPC分类号： A01C1/00
摘要： A method for managing seed includes non-destructively sampling individual seeds to assist in providing evaluation data for each of the individual seeds, storing the evaluation data and seed identifiers associated with each of the individual seeds in a data store, selecting a subset of seed for planting at least partially based on the evaluation data, and planting the subset of seed. A system for management of seed on an individual seed basis includes an evaluation subsystem for evaluating individual non-destructively sampled seeds to provide evaluation data for the seeds, a selection subsystem for selecting a subset of the individual seeds at least partially based on the evaluation data, and a planting subsystem for planting the subset of individual seeds.
摘要翻译：用于管理种子的方法包括非破坏性地采样个体种子以帮助提供每个个体种子的评估数据，将评估数据和与每个个体种子相关联的种子识别符存储在数据存储器中，为种子种子选择子集至少部分地基于评估数据进行种植，并种植种子子集。用于在个体种子基础上管理种子的系统包括用于评估单独的非破坏性采样的种子以提供种子的评估数据的评估子系统，用于至少部分地基于评估数据选择个体种子子集的选择子系统以及用于种植个体种子子集的种植子系统。

4. 发明申请

WO2010033430A1 AUTOMATED RESEARCH PLANTING SYSTEM, METHOD, AND APPARATUS 审中-公开
标题翻译：自动研究系统，方法和装置
公开(公告)号：WO2010033430A1
公开(公告)日：2010-03-25
申请号：PCT/US2009/056652
申请日：2009-09-11
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , GOLDMAN, Daniel, M. , HUNTER, James, L. , JOHNSON, David, L. , MEYER, Timothy, P. , SCHROEDER, Lyndon, J. , WILHELM, Timothy, J.
发明人： GOLDMAN, Daniel, M. , HUNTER, James, L. , JOHNSON, David, L. , MEYER, Timothy, P. , SCHROEDER, Lyndon, J. , WILHELM, Timothy, J.
IPC分类号： A01B79/00 , A01C21/00
CPC分类号： A01B79/005 , A01C21/005
摘要： The present invention provides an automated research seed planting system (100), method, and apparatus (102). The system, method, and apparatus may include a planter configured for planting a research plot and comprising a seed package assembly handling device (104) configured to receive a seed package assembly (200) containing a research seed sample, and a controller (103) configured to communicate with the seed package assembly handling device (104). The controller (103) is configured to automatically control the seed package assembly handling device (104) to release the research seed sample. In various embodiments, the research seed planter (102) may include a positional data acquisition system (115) configured to acquire position data associated with one or more research seed planting events.
摘要翻译：本发明提供一种自动研究种子种植系统（100），方法和装置（102）。系统，方法和装置可以包括配置用于种植研究图并包括配置成接收包含研究种子样本的种子包装组件（200）的种子包组装处理装置（104）的种植机，以及控制器（103）被配置为与种子包组件处理装置（104）通信。控制器（103）被配置为自动控制种子包组件处理装置（104）以释放研究种子样本。在各种实施例中，研究种子播种器（102）可以包括位置数据获取系统（115），其被配置为获取与一个或多个研究种子种植事件相关联的位置数据。

5. 发明申请

WO2010011497A2 SYSTEM AND METHOD FOR COORDINATING PRODUCTION AND PROCESSING OF SEED SUPPLIES 审中-公开
标题翻译：用于协调种子生产和加工的系统和方法
公开(公告)号：WO2010011497A2
公开(公告)日：2010-01-28
申请号：PCT/US2009/049929
申请日：2009-07-08
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , HUNTER, James, L. , MEYER, Timothy, P
发明人： HUNTER, James, L. , MEYER, Timothy, P
IPC分类号： G06Q50/00 , G06F17/30
CPC分类号： G06Q10/087
摘要： A system and method for coordinating the production, processing, and utilization of seed is provided. In various embodiments, the method and system aggregate seed inventory data, identify seed requests, and query the seed requests against the seed supply information. If the query results in a match a seed source can be automatically identified. Further, identified seed can be automatically allocated to the identified seed request from the identified seed source.
摘要翻译：提供了一种协调种子生产，加工和利用的系统和方法。在各种实施例中，方法和系统聚合种子库存数据，识别种子请求，并针对种子供应信息查询种子请求。如果查询结果匹配，种子源可以自动识别。此外，所识别的种子可以从所识别的种子源自动分配给所识别的种子请求。

6. 发明申请

WO2009038748A2 SEED TESTING METHOD AND APPARATUS 审中-公开
标题翻译：种子测试方法和装置
公开(公告)号：WO2009038748A2
公开(公告)日：2009-03-26
申请号：PCT/US2008/010872
申请日：2008-09-19
申请人： KAMTERTER II, L.L.C. , PETERSEN, Christopher, Lee , EASTIN, John, Alvin , MEYER, Timothy, Raymond
发明人： PETERSEN, Christopher, Lee , EASTIN, John, Alvin , MEYER, Timothy, Raymond
IPC分类号： C12M1/34 , C12Q1/00
CPC分类号： A01C1/025 , G01N33/0098
摘要： To provide an accelerated aging seed testing kit system, a single sheet of plastic or other suitable formable sheet material is pressed into the shape of a compartment base having recesses for mounting a seed holder. A seed holder that includes a seed support and a seed support holder is formed. The seed support holder is formed of a single sheet of plastic having radially extending tabs that fit into the recesses of the container to support the seed support above the bottom of the test kit. A bypass channel for addition of an aqueous solution used in the prescribed test condition is provided in the seed holder. A lid is formed out of one piece of plastic having a bendable tab to serve as a port and the openings and connecting points of the lid and seed holder are positioned so they can only fit together in one orientation having the port above the bypass channel. The saturated cold germination test kit includes a compartment base, a lid and a holder for an oxygen scavenger. The base is water and airtight and includes a liquid gas exchange control trough around its perimeter. It is sized to house a high moisture holding seed planting surface pack at the bottom so seeds can be placed on top of the surface to imbibe and initiate pre- germination mechanisms. The lid has an edge that fits into a trough that houses a gas barrier liquid in the base to form an airtight seal and has an attachable compartment for an oxygen scavenger so the kit may be placed together in an airtight configuration with the oxygen scavenger inside to provide an anaerobic atmosphere for performing the saturated cold germination test in a cool location.
摘要翻译：为了提供加速老化种子测试试剂盒系统，将单片塑料或其它合适的可成形片材压制成具有用于安装种子保持器的凹部的隔室基座的形状。形成种子保持器，其包括种子支架和种子支撑架。种子支撑保持器由具有径向延伸的突片的单片塑料形成，所述突出部配合到容器的凹部中以将种子支撑件支撑在测试套件的底部之上。在种子保持器中提供用于添加在规定测试条件下使用的水溶液的旁路通道。盖子由一片塑料制成，具有可弯曲的接头以用作端口，并且盖子和种子保持器的开口和连接点被定位成使得它们只能在具有旁通通道上方的端口的一个取向上装配在一起。饱和冷发芽试验试剂盒包括隔室基座，盖子和用于除氧剂的保持器。基座是水和气密的，并且包括围绕其周边的液体气体交换控制槽。它的大小适合于在底部放置高含水量的种子种植面包，因此可将种子放置在表面顶部以吸收并启动发芽前机制。盖子具有一个边缘，该边缘装配在槽中，该槽在基座中容纳阻气液体以形成气密密封，并且具有用于除氧剂的可附接隔间，因此该试剂盒可以以气密构造放置在一起，而氧清除器内部提供厌氧气氛，在阴凉的地方进行饱和冷发芽试验。

7. 发明申请

WO2013116544A1 SYSTEMS AND METHODS FOR CONTROLLING A CARDIAC RESYNCHRONISATION DEVICE/THERAPY USING BIOMARKER PANEL DATA 审中-公开
标题翻译：用于控制使用生物标记面板数据的心脏再生装置/治疗的系统和方法
公开(公告)号：WO2013116544A1
公开(公告)日：2013-08-08
申请号：PCT/US2013/024185
申请日：2013-01-31
申请人： CARDIAC PACEMAKERS, INC. , STOLEN, Craig M. , MEDICAL UNIVERSITY OF SOUTH CAROLINA , MEYER, Timothy E. , SETH, Milan , SPINALE, Francis G. , WOLD, Nicholas David
发明人： STOLEN, Craig M. , MEYER, Timothy E. , SETH, Milan , SPINALE, Francis G. , WOLD, Nicholas David
IPC分类号： A61N1/362 , G01N33/68
CPC分类号： G01N33/6893 , A61B5/0031 , A61B5/076 , A61B5/14503 , A61B5/14546 , A61B5/686 , A61N1/3627 , A61N1/36557 , A61N1/3956 , G01N2800/52 , G06F19/00
摘要： Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data with respect to medical devices and methods, amongst other things. In an embodiment, a medical system is included having an external programmer device; and an implantable medical device, the implantable medical device configured to communicate with the programmer through a telemetry interface. The external programmer device can be configured to receive data regarding levels of one or more of a panel of biomarkers in a biological sample of a patient; the panel of biomarkers including at least one selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-n, IFNg, BNP, sST2, MMP-2, MMP-9, TEVIP-1, TEVIP-2, and TIMP-4. The external programmer device can be configured to process the data regarding the levels of one or more of the panel of biomarkers. In an embodiment, a method of predicting the likelihood of response to CRT therapy in included. Other embodiments are also included herein.
摘要翻译：本公开的实施例涉及用于利用关于医疗装置和方法的生物标志物面板数据的系统和方法。在一个实施例中，包括具有外部编程器装置的医疗系统; 以及可植入医疗装置，所述可植入医疗装置被配置为通过遥测接口与所述编程器进行通信。外部编程器装置可以被配置为接收关于患者的生物样品中生物标志物组中的一个或多个的水平的数据; 所述生物标志物组包括选自CRP，SGP-130，sIL-2R，sTNFR-n，IFNg，BNP，sST2，MMP-2，MMP-9，TEVIP-1，TEVIP-2，和TIMP-4。外部编程器装置可被配置为处理关于生物标志物的一个或多个面板的水平的数据。在一个实施例中，预测包括对CRT治疗的可能性的预测方法。本文还包括其它实施例。

8. 发明申请

WO2011153127A1 INTEGRATING SENSORS AND BIOMARKER ASSAYS TO DETECT WORSENING HEART FAILURE 审中-公开
标题翻译：整合传感器和生物标记测试以检测心脏衰竭
公开(公告)号：WO2011153127A1
公开(公告)日：2011-12-08
申请号：PCT/US2011/038514
申请日：2011-05-31
申请人： CARDIAC PACEMAKERS, INC. , THAKUR, Pramodsingh, Hirasingh , PATANGAY, Abhilash , STOLEN, Craig , MEYER, Timothy
发明人： THAKUR, Pramodsingh, Hirasingh , PATANGAY, Abhilash , STOLEN, Craig , MEYER, Timothy
IPC分类号： A61B5/085 , A61N1/37
CPC分类号： A61B5/0205 , A61B5/0022 , A61B5/0031 , A61B5/02 , A61B5/08 , A61B7/00 , A61B2505/07 , A61N1/3627 , A61N1/36521 , A61N1/3702 , A61N1/37258 , G06F19/00
摘要： Physiological sensor data can be combined with external biomarker assays, such as a bedside assay for B-type natriuretic peptide (BNP), to improve the sensitivity and specificity of heart failure detection.
摘要翻译：生理传感器数据可与外部生物标志物检测结合，如B型利尿钠肽（BNP）的床边检测，以提高心力衰竭检测的灵敏度和特异性。

9. 发明申请

WO2009064400A1 SYSTEM FOR NEURAL THERAPY 审中-公开
标题翻译：神经系统治疗
公开(公告)号：WO2009064400A1
公开(公告)日：2009-05-22
申请号：PCT/US2008/012681
申请日：2008-11-12
申请人： CARDIAC PACEMAKERS, INC. , SHUROS, Allan C. , STOLEN, Craig , MEYER, Timothy , RUBLE, Stephen
发明人： SHUROS, Allan C. , STOLEN, Craig , MEYER, Timothy , RUBLE, Stephen
IPC分类号： A61N1/34 , A61N1/36 , A61N1/08
CPC分类号： A61N1/08 , A61N1/36071 , A61N1/36114
摘要： This document discusses, among other things, a system and method for calculating a neural stimulation energy at an external patient management (EPM) system using received information about a chemical characteristic indicative of a physiological state of a subject.
摘要翻译：本文件尤其涉及使用接收到的关于指示受试者的生理状态的化学特性的信息来计算外部患者管理（EPM）系统的神经刺激能量的系统和方法。

10. 发明申请

WO2008006063A2 SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR AUTOMATED HIGH-THROUGHPUT SEED SAMPLE ALIQUOT PREPARATION, TREATMENT, AND DISPERSAL 审中-公开
标题翻译：用于自动高通量样品样品制备，处理和分散的系统，方法和计算机程序产品
公开(公告)号：WO2008006063A2
公开(公告)日：2008-01-10
申请号：PCT/US2007072945
申请日：2007-07-06
申请人： PIONEER HI BRED INT , HOOD FRED C , HUNTER JAMES L , MEYER TIMOTHY P , SCHROEDER LYNDON J
发明人： HOOD FRED C , HUNTER JAMES L , MEYER TIMOTHY P , SCHROEDER LYNDON J
CPC分类号： A01C1/00
摘要： A system, method, and computer program product for separating a seed aliquot from a bulk sample and preparing the seed aliquot for downstream research purposes is provided. The system embodiments may comprise a counter device, which is configured to receive at least a portion of the bulk sample and to separate the seed aliquot from the portion of the bulk sample, and a packaging device, which is configured to receive the separated seed aliquot and to dispense the aliquot into an aliquot container. Other embodiments may include a conveyor system for advancing the bulk sample and/or seed aliquot along a conveyance path that may be determined from a research protocol received from an input source. Various embodiments of the present invention may maintain an identity of the seed aliquot as it is advanced along the conveyance path and may selectively subject the seed aliquot to a variety of processing steps in accordance with the research protocol with little or no manual control or supervision.
摘要翻译：提供了一种用于从种子样品中分离种子等分试样并制备用于下游研究目的的种子等分试样的系统，方法和计算机程序产品。系统实施例可以包括对抗装置，其被配置为接收批量样品的至少一部分并且将种子等分试样与批量样品的部分分离，以及包装装置，其被配置为接收分离的种子等分试样并将等分试样分配到等分试样容器中。其他实施例可以包括用于沿着可以根据从输入源接收的研究协议确定的输送路径推进大块样品和/或种子等分试样的输送机系统。本发明的各种实施方案可以沿着输送路径保持种子等分试样的身份，并且可以根据研究方案将种子等分试样选择性地对待各种处理步骤，而很少或没有手动控制或监督。

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