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1. 发明申请

WO2011163379A3 HIGH WORKLOAD INJECTION SYSTEM 审中-公开
标题翻译：高工作注射系统
公开(公告)号：WO2011163379A3
公开(公告)日：2012-04-19
申请号：PCT/US2011041471
申请日：2011-06-22
申请人： BIOJECT INC , WILLIAMSON DANIEL E , MARSHALL JOHN R
发明人： WILLIAMSON DANIEL E , MARSHALL JOHN R
IPC分类号： B65B3/12 , A61J1/06 , A61J1/20 , A61J3/00 , B65B3/04
CPC分类号： A61M5/1782 , A61M5/24 , A61M5/30 , B65B3/003
摘要： A filling device for a needle-free injector system is provided that is adapted to sterilely deliver a predetermined amount of an injectate from a vial to a plurality of cartridges. The filling device normally includes a single-use fluid path disposed between the vial and a receiving cartridge. The fluid path may include a vial connector adapted to couple to a vial, a filler head, and a conduit connecting the vial connector and filler head. The filling device typically further includes a pump coupled to the fluid path and adapted to propel the injectate from the vial to the receiving cartridge, and a cartridge-advancing element. Activation of the cartridge-advancing element is adapted to sequentially advance empty cartridges into a position opposite the filler head. Also provided are disposable fluid path kits and methods of using the filling device.
摘要翻译：提供了一种用于无针注射器系统的填充装置，其适于将预定量的注射器从小瓶输送到多个药筒。填充装置通常包括设置在小瓶和接收盒之间的一次性流体路径。流体路径可以包括适于联接到小瓶，填充头和连接小瓶连接器和填充头的导管的小瓶连接器。填充装置通常还包括耦合到流体路径并适于将注射器从小瓶推进到接收盒的泵和盒推进元件。盒前进元件的激活适于将空墨盒顺序地提前到与填充头相对的位置。还提供了一次性流体路径套件和使用填充装置的方法。

2. 发明申请

WO2005054582A1 TRAFFIC CONTROL BARRIERS 审中-公开
标题翻译：交通控制障碍
公开(公告)号：WO2005054582A1
公开(公告)日：2005-06-16
申请号：PCT/GB2004/004419
申请日：2004-10-20
申请人： CORUS UK LIMITED , BOWERMAN, Hugh, G. , GIBBS, Lawrence, W. , TOLLOCZKO, Jurek, J., A. , WHITTON, John, H. , MARSHALL, John, R.
发明人： BOWERMAN, Hugh, G. , GIBBS, Lawrence, W. , TOLLOCZKO, Jurek, J., A. , WHITTON, John, H. , MARSHALL, John, R.
IPC分类号： E01F13/02
CPC分类号： E01F13/026 , E01F15/083 , E01F15/088
摘要： A traffic control barrier comprises at least two side-by-side elongate solid blocks whose sides are detachably connected together by one or more metallic connectors. The longitudinal axis of the or each connector extends in a direction transverse to the longitudinal axis of each block and in plan view, each block may be generally elliptical or rectangular.
摘要翻译：交通控制障碍物包括至少两个并排的细长实心块，其侧面通过一个或多个金属连接器可拆卸地连接在一起。该连接器或每个连接器的纵向轴线在横向于每个块的纵向轴线的方向上延伸，并且在平面图中，每个块可以是大致椭圆形或矩形的。

3. 发明申请

WO2011163382A2 INTRADERMAL INJECTION DEVICE 审中-公开
标题翻译：内窥镜注射装置
公开(公告)号：WO2011163382A2
公开(公告)日：2011-12-29
申请号：PCT/US2011/041476
申请日：2011-06-22
申请人： BIOJECT, INC. , WILLIAMSON, Daniel, E. , MARSHALL, John, R.
发明人： WILLIAMSON, Daniel, E. , MARSHALL, John, R.
IPC分类号： A61M5/30 , A61M5/28 , A61J1/20
CPC分类号： A61J1/2096 , A61J1/201 , A61M5/1782 , A61M5/2033 , A61M5/30 , A61M2005/202
摘要： Embodiments herein relate to the field of injections, for instance needle- free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle- free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device.
摘要翻译：本文的实施方案涉及注射领域，例如无针注射，更具体地，涉及用于弹簧驱动的肌内和皮内注射的方法和装置。在一些实施例中提供了适用于递送皮内注射的无针注射器，以及当与无针注射装置一起使用时适于作为间隔物的小瓶适配器。

4. 发明申请

WO2009070603A1 NEEDLE-FREE INJECTION DEVICE WITH AUTO-DISABLE 审中-公开
标题翻译：具有自动禁用的无针注射装置
公开(公告)号：WO2009070603A1
公开(公告)日：2009-06-04
申请号：PCT/US2008/084735
申请日：2008-11-25
申请人： BIOJECT INC. , MARSHALL, John, R. , WILLIAMSON, Daniel, E. , LANDAU, Sergio
发明人： MARSHALL, John, R. , WILLIAMSON, Daniel, E. , LANDAU, Sergio
IPC分类号： A61M5/30
CPC分类号： A61M5/30
摘要： Needle-free injection devices having a body, an actuation system, and a delivery system including a drive assembly and configured to receive a nozzle assembly. In some embodiments, the drive assembly includes a spring and a support member configured to restrict movement of the spring in a direction non- parallel to a central axis of the spring. In some embodiments, the drive assembly includes a transmission assembly configured to couple a drive source with the actuation system upon engagement of a nozzle assembly with the drive assembly. In some embodiments, the body is configured to acoustically seal an interface between the delivery system and the actuation system. In some embodiments, the body includes a gripping member selectively extendable from the body.
摘要翻译：具有主体，致动系统和输送系统的无针注射装置，其包括驱动组件并构造成接收喷嘴组件。在一些实施例中，驱动组件包括弹簧和构造成限制弹簧在不平行于弹簧的中心轴线的方向上的运动的支撑构件。在一些实施例中，驱动组件包括传动组件，该传动组件构造成在喷嘴组件与驱动组件接合时将驱动源与致动系统联接。在一些实施例中，主体构造成声音地密封输送系统和致动系统之间的界面。在一些实施例中，主体包括可选择地从主体延伸的夹持构件。

5. 发明申请

WO2004073554A2 NEEDLE-FREE INJECTION SYSTEM 审中-公开
标题翻译：无针注射系统
公开(公告)号：WO2004073554A2
公开(公告)日：2004-09-02
申请号：PCT/US2004/005176
申请日：2004-02-19
申请人： BIOJECT, INC. , LANDAU, Sergio , MARSHALL, John, R.
发明人： LANDAU, Sergio , MARSHALL, John, R.
IPC分类号： A61F
CPC分类号： B65B3/003 , A61M5/1782
摘要： The present invention provides method and apparatus for providing high throughput injections. In one embodiment the invention provides a filling device adapted to deliver injectate from a common reservoir to a plurality of disposable fluid injection assemblies and a reusable propulsion assembly adapted to receive a filled disposable fluid injection assembly and deliver an injection to a patient.
摘要翻译：本发明提供了用于提供高通量注射的方法和装置。在一个实施例中，本发明提供一种适于将注射器从公共储存器输送到多个一次性流体注射组件的填充装置和适于接收填充的一次性流体注射组件并将注射物递送给患者的可重复使用的推进组件。

6. 发明申请

WO2011163382A3 INTRADERMAL INJECTION DEVICE 审中-公开
标题翻译：内窥镜注射装置
公开(公告)号：WO2011163382A3
公开(公告)日：2012-04-12
申请号：PCT/US2011041476
申请日：2011-06-22
申请人： BIOJECT INC , WILLIAMSON DANIEL E , MARSHALL JOHN R
发明人： WILLIAMSON DANIEL E , MARSHALL JOHN R
IPC分类号： A61M5/30 , A61J1/20 , A61M5/28
CPC分类号： A61J1/2096 , A61J1/201 , A61M5/1782 , A61M5/2033 , A61M5/30 , A61M2005/202
摘要： Embodiments herein relate to the field of injections, for instance needle- free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle- free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device.
摘要翻译：本文的实施方案涉及注射领域，例如无针注射，更具体地，涉及用于弹簧驱动的肌内和皮内注射的方法和装置。在一些实施例中提供了适用于递送皮内注射的无针注射器，以及当与无针注射装置一起使用时适于作为间隔物的小瓶适配器。

7. 发明申请

WO2011163379A2 HIGH WORKLOAD INJECTION SYSTEM 审中-公开
标题翻译：高工作注射系统
公开(公告)号：WO2011163379A2
公开(公告)日：2011-12-29
申请号：PCT/US2011/041471
申请日：2011-06-22
申请人： BIOJECT, INC. , WILLIAMSON, Daniel, E. , MARSHALL, John, R.
发明人： WILLIAMSON, Daniel, E. , MARSHALL, John, R.
IPC分类号： B65B3/12 , B65B3/04 , A61J3/00 , A61J1/06 , A61J1/20
CPC分类号： A61M5/1782 , A61M5/24 , A61M5/30 , B65B3/003
摘要： A filling device for a needle-free injector system is provided that is adapted to sterilely deliver a predetermined amount of an injectate from a vial to a plurality of cartridges. The filling device normally includes a single-use fluid path disposed between the vial and a receiving cartridge. The fluid path may include a vial connector adapted to couple to a vial, a filler head, and a conduit connecting the vial connector and filler head. The filling device typically further includes a pump coupled to the fluid path and adapted to propel the injectate from the vial to the receiving cartridge, and a cartridge-advancing element. Activation of the cartridge-advancing element is adapted to sequentially advance empty cartridges into a position opposite the filler head. Also provided are disposable fluid path kits and methods of using the filling device.
摘要翻译：提供了一种用于无针注射器系统的填充装置，其适于将预定量的注射器从小瓶输送到多个药筒。填充装置通常包括设置在小瓶和接收盒之间的一次性流体路径。流体路径可以包括适于联接到小瓶，填充头和连接小瓶连接器和填充头的导管的小瓶连接器。填充装置通常还包括耦合到流体路径并适于将注射器从小瓶推进到接收盒的泵和盒推进元件。盒前进元件的激活适于将空墨盒顺序地提前到与填充头相对的位置。还提供了一次性流体路径套件和使用填充装置的方法。

8. 发明申请

WO2004073554A3 NEEDLE-FREE INJECTION SYSTEM 审中-公开
标题翻译：无针注射系统
公开(公告)号：WO2004073554A3
公开(公告)日：2004-11-25
申请号：PCT/US2004005176
申请日：2004-02-19
申请人： BIOJECT INC , LANDAU SERGIO , MARSHALL JOHN R
发明人： LANDAU SERGIO , MARSHALL JOHN R
IPC分类号： A61M5/178 , B65B3/00 , B65B1/04
CPC分类号： B65B3/003 , A61M5/1782
摘要： The present invention provides method and apparatus for providing high throughput injections. In one embodiment the invention provides a filling device adapted to deliver injectate from a common reservoir to a plurality of disposable fluid injection assemblies and a reusable propulsion assembly adapted to receive a filled disposable fluid injection assembly and deliver an injection to a patient.
摘要翻译：本发明提供了用于提供高通量注射的方法和装置。在一个实施例中，本发明提供了一种填充装置，其适于将注射液从公共容器递送至多个一次性流体注射组件，以及适于接收填充的一次性流体注射组件并且将注射递送至患者的可再用推进组件。

9. 发明申请

WO2009070605A1 NEEDLE-FREE INJECTION DEVICE WITH NOZZLE AUTO-DISABLE 审中-公开
标题翻译：无喷嘴自动注射装置，带有喷嘴自动禁用
公开(公告)号：WO2009070605A1
公开(公告)日：2009-06-04
申请号：PCT/US2008/084737
申请日：2008-11-25
申请人： BIOJECT INC. , LANDAU, Sergio , WILLIAMSON, Daniel, E. , MARSHALL, John, R.
发明人： LANDAU, Sergio , WILLIAMSON, Daniel, E. , MARSHALL, John, R.
IPC分类号： A61M5/50
CPC分类号： A61M5/30 , A61M5/31511 , A61M5/5066
摘要： A nozzle assembly for a needle-free injection device. The nozzle assembly includes a nozzle body including an injectate chamber and one or more outlet orifices and a plunger configured to move through the injectate chamber toward the one or more outlet orifices. In some embodiments, the plunger includes a first portion and a second portion removably joined by a frangible region. In some embodiments, the plunger includes extensions configured to couple the plunger to a drive assembly of a needle-free injection device.
摘要翻译：用于无针注射装置的喷嘴组件。喷嘴组件包括喷嘴主体，喷嘴主体包括注射室和一个或多个出口孔以及配置成朝向一个或多个出口孔移动通过注射室的柱塞。在一些实施例中，柱塞包括可拆卸地由易碎区域连接的第一部分和第二部分。在一些实施例中，柱塞包括构造成将柱塞耦合到无针注射装置的驱动组件的延伸部。

10. 发明申请

WO2003103752A1 NEEDLE-FREE INJECTION SYSTEM 审中-公开
标题翻译：无针注射系统
公开(公告)号：WO2003103752A1
公开(公告)日：2003-12-18
申请号：PCT/US2003/016446
申请日：2003-05-22
申请人： BIOJECT INC. , WILLIAMSON, Dan , LANDAU, Sergio , MARSHALL, John R.
发明人： WILLIAMSON, Dan , LANDAU, Sergio , MARSHALL, John R.
IPC分类号： A61M5/30
CPC分类号： A61M5/30
摘要： A needle-free injection device (22) includes a user-grippable housing (26) and a syringe assembly (28) movably secured to the housing (26). The syringe assembly (28) is configured to expel injectable fluid out of a nozzle (30) upon application of pressurized gas to the syringe assembly (28). The injection device (22) also includes a pressurized gas delivery mechanism (64) disposed within the housing (26) and configured to selectively apply pressurized gas to the syringe assembly (28). The pressurized gas delivery mechanism (64) is at least partly actuated by pressing the nozzle (30) onto an injection site so that the syringe assembly (28) moves relative to the housing (26).
摘要翻译：无针注射装置（22）包括可移动地固定到壳体（26）的用户可抓握的壳体（26）和注射器组件（28）。注射器组件（28）构造成在将注射液体施加到注射器组件（28）上时将可注射流体排出喷嘴（30）。注射装置（22）还包括设置在壳体（26）内的加压气体输送机构（64），并构造成选择性地将加压气体施加到注射器组件（28）。加压气体输送机构（64）至少部分地通过将喷嘴（30）压到注射部位来致动，使得注射器组件（28）相对于壳体（26）移动。

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