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1. 发明申请

WO2019041024A1 FGL2 ANTIBODIES AND BINDING FRAGMENTS THEREOF AND USES THEREOF 审中-公开
公开(公告)号：WO2019041024A1
公开(公告)日：2019-03-07
申请号：PCT/CA2018/050527
申请日：2018-05-03
申请人： LEVY, Gary , KHATTAR, Ramzi , CHRUSCINSKI, Andrzej , VANDERHYDEN, Barbara , MCCLOSKEY, Curtis
发明人： LEVY, Gary , KHATTAR, Ramzi , CHRUSCINSKI, Andrzej , VANDERHYDEN, Barbara , MCCLOSKEY, Curtis
IPC分类号： C07K16/28 , A61K39/395 , A61K47/68 , C07K16/18 , C07K16/30 , G01N33/53 , G01N33/574 , C07K16/36
摘要： The disclosure is directed to antibodies and binding fragments thereof that specifically bind FGL2. The disclosure is also directed to uses of the antibodies and binding fragments thereof for treating cancer.

2. 发明申请

WO2010124171A2 SYSTEM AND METHOD FOR INFORMATION DELIVERY INCLUDING DELIVERY VIA VIDEO-BASED KEYED OR TAGGED CONTENT 审中-公开
标题翻译：用于信息传递的系统和方法，包括基于视频键盘或标签内容的传送
公开(公告)号：WO2010124171A2
公开(公告)日：2010-10-28
申请号：PCT/US2010032180
申请日：2010-04-23
申请人： TELEGENT SYSTEMS INC , SHENG SAMUEL , BYDELEY DAVID , LEVY GARY , WANG QING
发明人： SHENG SAMUEL , BYDELEY DAVID , LEVY GARY , WANG QING
IPC分类号： H04N7/08 , H04N7/00
CPC分类号： H04N7/088 , H04H20/38 , H04H60/33 , H04H60/65 , H04H60/73 , H04N21/2353 , H04N21/4622 , H04N21/4667 , H04N21/472 , H04N21/858
摘要： An interactive device/system of and method for delivery, receipt and/or decoding of and/or response to keyed or tagged video content provided in connection with one or more video broadcasts (for example, television or streaming video). Responsive thereto, the system and method may deliver and/or receive video and/or audio information. Such delivery and/or receipt of video and/or audio information may be responsive to content embedded in the broadcast but not visually observed, responsive to broadcast content that is visually observed and then parsed and correlated with a predetermined response, and responsive to a user/operator instruction, input and/or request. The interactive video receiving device may determine a video-based broadcast is an interactive video-based broadcast, wherein, the device automatically provides interaction options and or based on a response by the user/viewer to the video-based broadcast, the video receiving device transmits "interest-level" data (i.e., data which is representative of the viewer's level of interest to the video-based broadcast) to obtain additional information regarding the video-based broadcast. Other inventions are also disclosed.
摘要翻译：用于与一个或多个视频广播（例如，电视或流式视频）相关联地提供的关键或标记的视频内容的交付，接收和/或解码和/或响应的交互设备/系统和方法。响应于此，系统和方法可以传送和/或接收视频和/或音频信息。视频和/或音频信息的这种传送和/或接收可以响应于在视频观察并随后被解析并与预定响应相关联并且响应于用户的广播内容而广播内容而不是视觉上观察到的内容 /操作员指令，输入和/或请求。交互式视频接收设备可以确定基于视频的广播是基于视频的交互式广播，其中，设备自动地提供交互选项，或者基于用户/观看者对基于视频的广播的响应，视频接收设备发送“利益级别”数据（即，代表观看者对基于视频的广播感兴趣的级别的数据），以获得关于基于视频的广播的附加信息。还公开了其它发明。

3. 发明申请

WO2003074068A2 USE OF SOLUBLE FGL2 AS AN IMMUNOSUPPRESSANT 审中-公开
标题翻译：使用可溶性FGL2作为免疫抑制剂
公开(公告)号：WO2003074068A2
公开(公告)日：2003-09-12
申请号：PCT/CA2003/000273
申请日：2003-02-28
申请人： TRILLIUM THERAPEUTICS INC. , LEVY, Gary
发明人： LEVY, Gary
IPC分类号： A61K38/00
CPC分类号： C12N9/647 , A61K38/00 , G01N2333/4753
摘要： Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a soluble fgl2 protein or a nucleic acid encoding a soluble fgl2 protein. The methods are useful in preventing graft rejection, autoimmune disease, and allergies.
摘要翻译：公开了用于诱导免疫抑制的方法和组合物。该方法涉及施用有效量的可溶性fgl2蛋白或编码可溶性fgl2蛋白的核酸。这些方法可用于预防移植排斥，自身免疫疾病和过敏。

4. 发明申请

WO2003066848A1 PORCINE FGL2 审中-公开
公开(公告)号：WO2003066848A1
公开(公告)日：2003-08-14
申请号：PCT/CA2003/000153
申请日：2003-02-07
申请人： TRILLIUM THERAPEUTICS INC. , LEVY, Gary , GHANEKAR, Anand , GRANT, David, R.
发明人： LEVY, Gary , GHANEKAR, Anand , GRANT, David, R.
IPC分类号： C12N9/64
CPC分类号： C07K16/18 , A01K2217/075 , A61K38/00 , C07K16/40 , C12N9/6424 , C12N9/647 , G01N33/6893 , G01N33/86 , G01N2500/04
摘要： The present invention relates to porcine fgl2 gene and protein and methods of modulating the gene and protein. The methods are useful in preventing thrombosis associated with the xenotransplantation of porcine organs or tissues.
摘要翻译：本发明涉及猪fgl2基因和蛋白质以及调节基因和蛋白质的方法。该方法可用于预防与猪器官或组织的异种移植相关的血栓形成。

5. 发明申请

WO2010124171A3 SYSTEM AND METHOD FOR INFORMATION DELIVERY INCLUDING DELIVERY VIA VIDEO-BASED KEYED OR TAGGED CONTENT 审中-公开
公开(公告)号：WO2010124171A3
公开(公告)日：2010-10-28
申请号：PCT/US2010/032180
申请日：2010-04-23
申请人： TELEGENT SYSTEMS, INC. , SHENG, Samuel , BYDELEY, David , LEVY, Gary , WANG, Qing
发明人： SHENG, Samuel , BYDELEY, David , LEVY, Gary , WANG, Qing
IPC分类号： H04N7/08 , H04N7/00
摘要： An interactive device/system of and method for delivery, receipt and/or decoding of and/or response to keyed or tagged video content provided in connection with one or more video broadcasts (for example, television or streaming video). Responsive thereto, the system and method may deliver and/or receive video and/or audio information. Such delivery and/or receipt of video and/or audio information may be responsive to content embedded in the broadcast but not visually observed, responsive to broadcast content that is visually observed and then parsed and correlated with a predetermined response, and responsive to a user/operator instruction, input and/or request. The interactive video receiving device may determine a video-based broadcast is an interactive video-based broadcast, wherein, the device automatically provides interaction options and or based on a response by the user/viewer to the video-based broadcast, the video receiving device transmits "interest-level" data (i.e., data which is representative of the viewer's level of interest to the video-based broadcast) to obtain additional information regarding the video-based broadcast. Other inventions are also disclosed.

6. 发明申请

WO2003074068A3 USE OF SOLUBLE FGL2 AS AN IMMUNOSUPPRESSANT 审中-公开
公开(公告)号：WO2003074068A3
公开(公告)日：2003-09-12
申请号：PCT/CA2003/000273
申请日：2003-02-28
申请人： TRILLIUM THERAPEUTICS INC. , LEVY, Gary
发明人： LEVY, Gary
IPC分类号： C12N9/64
摘要： Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a soluble fgl2 protein or a nucleic acid encoding a soluble fgl2 protein. The methods are useful in preventing graft rejection, autoimmune disease, and allergies.

7. 发明申请

WO2006086127A1 INTERCHANGEABLE RECEIVE INPUTS FOR BAND AND SYSTEM SWAPPABILITY IN COMMUNICATION SYSTEMS AND RELATED METHODS 审中-公开
标题翻译：通信系统中带宽和系统可交换的可接收接收输入及相关方法
公开(公告)号：WO2006086127A1
公开(公告)日：2006-08-17
申请号：PCT/US2006/001653
申请日：2006-01-19
申请人： SILICON LABORATORIES INC. , KERTH, Donald, A. , SRINIVASAN, Vishnu, S. , LEVY, Gary, B. , MITCHELSON, Brett, O. , GARLEPP, Eric, R. , TUTTLE, G., Tyson
发明人： SRINIVASAN, Vishnu, S. , LEVY, Gary, B. , MITCHELSON, Brett, O. , GARLEPP, Eric, R. , TUTTLE, G., Tyson
IPC分类号： H03G5/24 , H04B1/06
CPC分类号： H04B1/006
摘要： Interchangeable high band low-noise-amplifiers (LNAs) and low band low-noise-amplifiers (LNAs) and related methods are disclosed that greatly enhance the efficiency of designing handsets for different combinations of frequency bands. The input signals to particular pins on a receiver or transceiver integrated circuit (IC) are swappable such that multiple frequency bands can be input to the same input pins thereby allowing for simplified system design. Efficient programmable techniques are also disclosed for controlling a swap mode within communication ICs. These interchangeable or band swappable input paths, for example, can be utilized to allow interchangeability between high band (PCS, DCS) and low band (GSM, E-GSM) inputs for cellular communications. In this way, for example, handset manufacturers can build a single printed circuit board (PCB) that can be utilized for cellular communications in the United States of America, where 850 MHz (GSM) and 1900 MHz (PCS) bands are utilized, and in Europe, wherein 900 MHz (E-GSM) and 1800 MHz (DCS) bands are utilized.
摘要翻译：公开了可互换的高频带低噪声放大器（LNA）和低频带低噪声放大器（LNA）及相关方法，这大大提高了针对不同频带组合设计手机的效率。接收器或收发器集成电路（IC）上的特定引脚的输入信号是可交换的，使得可以将多个频带输入到相同的输入引脚，从而允许简化的系统设计。还公开了有效的可编程技术来控制通信IC内的交换模式。例如，这些可互换或频带可交换的输入路径可用于允许用于蜂窝通信的高频带（PCS，DCS）和低频（GSM，E-GSM）输入之间的互换性。以这种方式，例如，手机制造商可以构建可用于在美国使用850MHz（GSM）和1900MHz（PCS）频带的美国的蜂窝通信的单个印刷电路板（PCB），以及在欧洲，其中使用900MHz（E-GSM）和1800MHz（DCS）频带。

8. 发明申请

WO2011050459A1 METHODS AND USES FOR TREATING HEPATIC ISCHEMIA AND REPERFUSION INJURY 审中-公开
标题翻译：方法和用于治疗HEPATIC ISCHEMIA和REPERFUSION INJURY的用途
公开(公告)号：WO2011050459A1
公开(公告)日：2011-05-05
申请号：PCT/CA2010/001689
申请日：2010-10-27
申请人： VERITAS THERAPEUTICS INC. , LEVY, Gary , SELZNER, Markus
发明人： LEVY, Gary , SELZNER, Markus
IPC分类号： A61K39/395 , A61K31/7088 , A61P9/10 , G01N33/53
CPC分类号： G01N33/5064 , A61K31/7088 , A61K2039/505 , C07K16/40 , C07K2317/76 , G01N2333/75
摘要： The present disclosure provides a method of treating or preventing hepatic ischemia and reperfusion injury in an animal comprising administering an effective amount of an FGL2-FcγRIIB inhibitor to an animal in need thereof. Also provided herein are uses, compositions and screening assays for FGL2- FcγRIIB inhibitors useful in treating hepatic ischemia and reperfusion injury.
摘要翻译：本公开内容提供了在动物中治疗或预防肝缺血和再灌注损伤的方法，包括向有需要的动物施用有效量的FGL2-FcγRIIB抑制剂。本文还提供了可用于治疗肝缺血和再灌注损伤的FGL2-FcγRIIB抑制剂的用途，组合物和筛选试验。

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