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    • 2. 发明申请
    • ANIMAL MODELS CARRYING TUMORS EXPRESSING HUMAN PROSTATE CANCER-SPECIFIC ANTIGEN AND METHOD FOR ANALYZING PREVENTION AND TREATMENT EFFICACY OF DENDRITIC CELLS-DERIVED IMMUNOTHERAPEUTICS USING THE ABOVE
    • 携带肿瘤的动物模型表达人前列腺癌特异性抗原和分析预防和治疗使用上述细胞衍生的免疫球蛋白的治疗效果的方法
    • WO2006126864A1
    • 2006-11-30
    • PCT/KR2006/002028
    • 2006-05-27
    • CREAGENE INCLEE, Dong SungLEE, Woo BokJEON, Choon JuBAE, Yong Soo
    • LEE, Dong SungLEE, Woo BokJEON, Choon JuBAE, Yong Soo
    • A01K67/027
    • A01K67/0271A01K2227/105A01K2267/0331
    • The present invention relates to a method for analyzing the prevention and treatment efficacy of a dendritic cell- derived immunotherapeutic for prostate cancer using an animal model carrying tumors expressing a human prostate cancer- specific antigen, which comprises the steps of : (a) (a') administering to a normal animal other than human dendritic cells to be analyzed, or (a") administering to a normal animal other than human a cancer cell line expressing the human prostate cancer-specific antigen to induce cancer in the normal animal; (b) (b' ) administering to the animal the cancer cell line expressing the human prostate cancer-specific antigen to induce cancer in the animal when the step (a' ) is performed in the step (a) , or (b") administering to the animal with cancer dendritic cells to be analyzed when the step (a") is performed in the step (a) ; and (c) determining the prevention and treatment efficacy of the dendritic cells as immunotherapeutics for prostate cancer by measuring the formation or growth of cancer cells originated from the cancer cell line in the animal.
    • 本发明涉及使用携带表达人前列腺癌特异性抗原的肿瘤的动物模型分析树突状细胞衍生的前列腺癌免疫治疗剂的预防和治疗功效的方法,其包括以下步骤:(a)(a) 对于待分析的人树突细胞以外的正常动物施用,或(a)向表达人前列腺癌特异性抗原的癌细胞系的除人之外的正常动物施用以在正常动物中诱导癌症的(a“) b)(b')在步骤(a')或(b“)中施用步骤(a')或(b”)时向动物施用表达人前列腺癌特异性抗原的癌细胞系以在动物中诱导癌症 在步骤(a“)中在步骤(a)中进行分析的具有癌症树突状细胞的动物;和(c)通过测定来确定树突状细胞作为前列腺癌的免疫治疗剂的预防和治疗功效 环绕来自动物的癌细胞系的癌细胞的形成或生长。
    • 4. 发明申请
    • COMPOSITION OF SKIN EXTERNAL APPLICATION CONTAINING GINSENG FRUIT EXTRACTS
    • 含有金山果实提取物的皮肤外用剂组合物
    • WO2008147148A1
    • 2008-12-04
    • PCT/KR2008/003069
    • 2008-05-30
    • AMOREPACIFIC CORPORATIONPARK, Chan-WoongYEOM, Myeong HoonLEE, Jin YoungJEON, Hee YoungLEE, Sang JunCHO, Nam HoonLEE, Dong Sung
    • PARK, Chan-WoongYEOM, Myeong HoonLEE, Jin YoungJEON, Hee YoungLEE, Sang JunCHO, Nam HoonLEE, Dong Sung
    • A23L1/307
    • A23L1/3002A23L33/105A23V2002/00A61K8/97A61K36/258A61K2800/522A61Q19/02A61Q19/08A23V2250/2124A23V2200/318A23V2200/332
    • Disclosed herein is a. skin external composition containing ginseng berry extract. More specifically, disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract having the specific components and compositions, among the above- ground parts of ginseng, and thus promotes the production of collagen in the skin, shows an MMP-I inhibitory effect and, at the same time, has skin-aging inhibitory and wrinkle-reducing effects, resulting from antioxidant effects and DNA damage-protecting effects. Also disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract, which has a skin whitening effect resulting from the effects of inhibiting melanin production and reducing pigmentation caused by UV radiation, the effects of relieving dry skin symptoms and atopic symptoms by inducing and maintaining the normal differentiation of skin keratinocytes, the effect of relieving acne and skin troubles by the regulation of sebum secretion and an anti-inflammatory effect, and makes complexion ruddy through the improvement of peripheral blood circulation to make the skin clean and clear. Also disclosed is a food composition for reducing and preventing obesity, which contains, as an active ingredient, ginseng berry extract, which increases the expression of a carnitine palmitoyl transterase-1 (CPT-I) gene, serves to transport fatty acids into mitochondria in fatty acid oxidation and promotes fat oxidation.
    • 本文公开的是 皮肤外用组合物含人参浆果提取物。 更具体地,公开了皮肤外用组合物,其含有作为活性成分的具有人参的上述地面部分中的具体成分和组成的人参浆果提取物,从而促进皮肤中的胶原蛋白的产生, MMP-1抑制作用,同时具有由抗氧化作用和DNA损伤保护作用产生的皮肤衰老抑制和皱纹减轻作用。 还公开了一种皮肤外用组合物,其含有作为活性成分的人参浆果提取物,其具有由抑制黑色素产生和减少由紫外线辐射引起的色素沉着的作用而产生的皮肤美白效果,减轻干性皮肤症状的效果和 通过诱导和维持皮肤角质形成细胞的正常分化,减轻痤疮和皮肤麻烦的作用,通过调节皮脂分泌和抗炎作用而产生特应性症状,并通过改善外周血液循环使肤色变红,使皮肤清洁 并清楚 还公开了用于减少和预防肥胖的食物组合物,其含有作为活性成分的人参果实提取物,其增加肉碱棕榈酰转氨酶-1(CPT-1)基因的表达,用于将脂肪酸运输到线粒体中 脂肪酸氧化并促进脂肪氧化。
    • 5. 发明申请
    • DEVICE FOR PROCESSING MATERIALS BY LASER BEAM
    • 激光加工材料的装置
    • WO2008111705A1
    • 2008-09-18
    • PCT/KR2007/002925
    • 2007-06-15
    • SNU PRECISION CO., LTD.PAHK, Heui JaeKIM, Tai WookLEE, Dong SungSHIN, Ng Hyun
    • PAHK, Heui JaeKIM, Tai WookLEE, Dong SungSHIN, Ng Hyun
    • B23K26/00
    • B23K26/067
    • Disclosed is a laser processing device for processing a surface of an object with laser beams. The laser processing device includes: a laser beam generating unit for projecting laser beams; and a micromirror device having a plurality of micromirrors, the micromirrors being configured to reflect and transfer at least a part of laser beams projected from the laser beam generating unit to the surface of the object in a pattern for processing the surface of the object in a desired shape. The micromirrors of the micromirror device are capable of selectively switching the light path of the laser beams projected from the laser beam generating unit. According to the present invention, a surface of an object can be either two-dimensionally or three-dimensionally processed in a desired shape with laser beams.
    • 公开了一种用激光束处理物体表面的激光加工装置。 激光加工装置包括:激光束产生单元,用于投射激光束; 以及具有多个微镜的微反射镜装置,所述微镜被配置为将以从所述激光束产生单元投影的至少一部分激光束以用于处理所述物体的表面的图案的形式反射并传送到所述物体的表面 所需形状。 微镜器件的微镜能够选择性地切换从激光束产生单元投影的激光束的光路。 根据本发明,物体的表面可以用激光束二维或三维地加工成所需的形状。