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1. 发明申请

WO2007064117A1 AFFINITY CHROMATOGRAPHY MICRODEVICE AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：亲和色谱微型装置及其制造方法
公开(公告)号：WO2007064117A1
公开(公告)日：2007-06-07
申请号：PCT/KR2006/005022
申请日：2006-11-27
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Dae-Sik , YOON, Hyun-Cheol , CHUNG, Kwang-Hyo , PYO, Hyeon-Bong , CHOI, Chang-Auck
发明人： LEE, Dae-Sik , YOON, Hyun-Cheol , CHUNG, Kwang-Hyo , PYO, Hyeon-Bong , CHOI, Chang-Auck
IPC分类号： G01N30/64 , G01N30/02
CPC分类号： G01N30/6095 , B01L3/502707 , B01L2200/147 , B01L2300/0636 , B01L2300/0645 , B01L2300/0877 , B01L2300/1827 , B82Y30/00 , B82Y40/00 , G01N30/02 , B01D15/3804
摘要： An affinity chromatography microdevice includes a top board and a bottom board. The top board includes an inlet and an outlet through which microfluid flows, and a reaction chamber for limiting the flow of the microfluid for reaction. The bottom board includes a microelectrode for independently controlling a micro-temperature, and a thermosensitive polymer matrix formed on the microelectrode. The thermosensitive polymer matrix is contracted or expanded according to temperature change.
摘要翻译：亲和层析微装置包括顶板和底板。顶板包括微流体流过的入口和出口，以及用于限制用于反应的微流体流动的反应室。底板包括用于独立控制微温度的微电极和形成在微电极上的热敏聚合物基体。热敏聚合物基体根据温度变化而收缩或膨胀。

2. 发明申请

WO2009072715A1 MICRO-SCALED ANIMAL CELL INCUBATOR AND PRODUCTION METHOD THEREOF 审中-公开
标题翻译：微量级动物细胞培养物及其生产方法
公开(公告)号：WO2009072715A1
公开(公告)日：2009-06-11
申请号：PCT/KR2008/003741
申请日：2008-06-27
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , CHOI, Yo Han , CHUNG, Kwang Hyo , LEE, Dae Sik , KIM, Sang Hee , JEONG, Min Suk , JUN, Chi Hoon , JUNG, Moon Youn , PARK, Seon Hee
发明人： CHOI, Yo Han , CHUNG, Kwang Hyo , LEE, Dae Sik , KIM, Sang Hee , JEONG, Min Suk , JUN, Chi Hoon , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： C12M3/00
CPC分类号： C12M23/20 , B01L3/5027 , B01L7/00 , C12M23/16 , C12M41/12 , Y10T29/49124
摘要： There is provided a cell culture technology for culturing an animal cell in a separate microstructure. The micro-scaled animal cell incubator includes a lower glass substrate having fine hot wires processed with a metal and formed in an upper surface thereof; a first PDMS film attached onto the lower glass substrate to form two or more liquid and solid storage spaces in a position corresponding to the fine hot wires of the lower glass substrate and gas flow channels coupled respectively to the liquid and solid storage spaces to allow generated gases to flow therethrough; a gas-permeable PDMS thin film attached onto the gas flow channels of the PDMS film to pass the generated gases therethrough; a second PDMS film attached onto the PDMS thin film and having a culture medium storage space for storing a culture medium; and an upper glass substrate attached onto the second PDMS film and having fine hot wires formed in a lower surface thereof, the fine hot wires being covered by the PDMS film. The micro-scaled animal cell incubator may be useful to control a temperature of a culture medium to a suitable temperature level, as well as to self-supply gases required for the animal cell culture in a microstructure.
摘要翻译：提供了用于在单独的微结构中培养动物细胞的细胞培养技术。微型动物细胞培养箱包括具有用金属加工并形成在其上表面的细微热丝的下玻璃基板; 附着在下玻璃基板上的第一PDMS膜，以形成两个或更多个液体和固体存储空间，该液体和固体储存空间位于对应于分别与液体和固体储存空间相连的下部玻璃基板和气体流动通道的细微热线的位置，以允许产生气体流过其中; 透气的PDMS薄膜，附着在PDMS薄膜的气流通道上，以使产生的气体通过; 附着在PDMS薄膜上并具有用于储存培养基的培养基存储空间的第二PDMS膜; 以及附着在第二PDMS膜上并具有形成在其下表面上的精细热丝的上玻璃基板，细的热丝被PDMS膜覆盖。微量级动物细胞培养箱可用于将培养基的温度控制到合适的温度水平，以及自动供应在微结构中动物细胞培养所需的气体。

3. 发明申请

WO2008069551A1 MICRO FLUIDIC TRANSPORTATION DEVICE AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：微流体运输装置及其制造方法
公开(公告)号：WO2008069551A1
公开(公告)日：2008-06-12
申请号：PCT/KR2007/006254
申请日：2007-12-04
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Dae-Sik , MAENG, Sung-Lyul , LUO, Jack , MILNE, Bill
发明人： LEE, Dae-Sik , MAENG, Sung-Lyul , LUO, Jack , MILNE, Bill
IPC分类号： B81B7/00
CPC分类号： F04B19/006 , B01L3/502707 , B01L3/50273 , B01L2300/0816 , B01L2400/0439 , B01L2400/0496 , F04F7/00 , Y10T29/42 , Y10T137/86027
摘要： Provided is a micro fluidic transportation device capable of controlling discontinuous transportation of micro droplets using surface acoustic wave (SAW), and a method for manufacturing the same. The micro fluidic transportation device which includes: a substrate; a piezoelectric layer formed on the substrate; an inter digitated transducer (IDT) electrode formed on the piezoelectric layer for energy conversion by generating a surface acoustic wave (SAW); and a fluid passage formed on the piezoelectric thin layer.
摘要翻译：提供一种能够使用表面声波（SAW）控制微滴的不连续输送的微流体输送装置及其制造方法。微流体输送装置，包括：基板; 形成在基板上的压电层; 通过产生表面声波（SAW）在压电层上形成用于能量转换的数字化换能器（IDT）电极; 以及形成在压电薄层上的流体通道。

4. 发明申请

WO2008069554A1 BIOCHIP READER 审中-公开
标题翻译：生物阅读器
公开(公告)号：WO2008069554A1
公开(公告)日：2008-06-12
申请号：PCT/KR2007/006257
申请日：2007-12-04
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Dae-Sik , SOHN, Mi-Jin , CHUNG, Kwang-Hyo , PYO, Hyeon-Bong , PARK, Seon-Hee
发明人： LEE, Dae-Sik , SOHN, Mi-Jin , CHUNG, Kwang-Hyo , PYO, Hyeon-Bong , PARK, Seon-Hee
IPC分类号： G01N33/483 , B81C1/00
CPC分类号： G01N21/8483
摘要： Provided is a biochip reader which can analyze an optical detection result obtained from a biochip or strip chip, and transmit and receive the analysis result in a bio-microelectromechanical system (bio-MEMS) field. The reader for reading a target chip inserted thereinto includes: a light emitter including a three-color light emitting elements; a light receiver configured to receive light generated in the light emitter, reflected or refracted by the target chip, or transmitted through the target chip, and convert the received light into an electric signal; an analyzer configured to drive the light emitter in a switching manner when the target chip is inserted, and analyze the electric signal transmitted from the light emitter; a storage unit configured to store a program to be executed by the analyzer and temporarily store an analysis result outputted from the analyzer; and a display unit configured to display the analysis result.
摘要翻译：提供了一种生物芯片读取器，其可以分析从生物芯片或条形芯片获得的光学检测结果，并且在生物微机电系统（bio-MEMS）领域中发送和接收分析结果。用于读取插入其中的目标芯片的读取器包括：包括三色发光元件的发光器; 光接收器，被配置为接收在所述光发射器中产生的光，由所述目标芯片反射或折射，或者透过所述目标芯片，并将所接收的光转换为电信号; 分析器，配置为当目标芯片插入时以开关方式驱动发光器，并分析从发光器发送的电信号; 存储单元，被配置为存储由分析器执行的程序，并临时存储从分析器输出的分析结果; 以及显示单元，被配置为显示分析结果。

5. 发明申请

WO2009061017A1 BIO LAB-ON-A-CHIP AND METHOD OF FABRICATING AND OPERATING THE SAME 审中-公开
公开(公告)号：WO2009061017A1
公开(公告)日：2009-05-14
申请号：PCT/KR2007/005655
申请日：2007-11-09
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Dae Sik , PARK, Rae Man , MAENG, Sung Lyul , JUNG, Moon Youn , PARK, Seon Hee
发明人： LEE, Dae Sik , PARK, Rae Man , MAENG, Sung Lyul , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： G01N33/48
CPC分类号： G01N33/54366 , B01L3/502707 , B01L3/50273 , B01L2200/0673 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/089 , B01L2300/161 , B01L2400/0436 , B01L2400/0496 , G01N33/5438
摘要： Disclosed is a bio lab-on-a-chip. The bio lab-on-a-chip is provided on a piez)electric thin film on a substrate, and includes a sensing unit to sense a bio signal and a fluidic control unit which controls a transfer of a microfluid adjacent to the sensing unit. Provided is also a method of fabricating the bio lab-on-a-chip. The method includes the steps of forming a piez)electric thin film, forming a sensing unit to sense a bio signal of a microfluid on the piez)electric thin film, and forming a fluidic control unit located adjacent to the sensing unit.
摘要翻译：公开了一种生物实验室芯片。芯片上的生物实验室被提供在基板上的压电薄膜上，并且包括用于感测生物信号的感测单元和控制与感测单元相邻的微流体传输的流体控制单元。还提供了一种制造生物芯片实验室的方法。该方法包括形成压电薄膜的步骤，形成感测单元以感测压电薄膜上的微流体的生物信号，以及形成位于感测单元附近的流体控制单元。

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